Plecotus auritus (brown big-eared bat): 308243574
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Entry
308243574 CDS
T11911
Symbol
ERBB3, AC0HY7_010407
Name
(RefSeq) receptor tyrosine-protein kinase erbB-3
KO
K05084
receptor tyrosine-protein kinase erbB-3 [EC:
2.7.10.1
]
Organism
pots Plecotus auritus (brown big-eared bat)
Pathway
pots01521
EGFR tyrosine kinase inhibitor resistance
pots04010
MAPK signaling pathway
pots04012
ErbB signaling pathway
pots04020
Calcium signaling pathway
pots04151
PI3K-Akt signaling pathway
pots05205
Proteoglycans in cancer
pots05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
pots00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
308243574 (ERBB3)
04012 ErbB signaling pathway
308243574 (ERBB3)
04020 Calcium signaling pathway
308243574 (ERBB3)
04151 PI3K-Akt signaling pathway
308243574 (ERBB3)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
308243574 (ERBB3)
05205 Proteoglycans in cancer
308243574 (ERBB3)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
308243574 (ERBB3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pots01001
]
308243574 (ERBB3)
Enzymes [BR:
pots01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
308243574 (ERBB3)
Protein kinases [BR:
pots01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
308243574 (ERBB3)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Furin-like
Pkinase
TM_ErbB1
Kinase-like
Motif
Other DBs
NCBI-GeneID:
308243574
NCBI-ProteinID:
XP_080515335
LinkDB
All DBs
Position
3:complement(170334828..170352901)
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AA seq
1339 aa
AA seq
DB search
MRANRALQVLGFLLSLARGSEVGNSQSVCPGTLNGLSVTGDAENQYQTLHKQYERCEVVM
GNLEIVLTGHNADLSFLQWIREVTGYVLVAMNEFSTLPLPNLRVVRGTQVYDGKFAIFVM
LNYNTNSSHALRQLGFTQLTEILSGGVYIEKNDKLCHMDTIDWRDIVRDRDAEIVVKDNG
RSCASCHAVCNGRCWGPGPKDCQTLTKTICAPQCNGHCFGPDPNQCCHDECAGGCSGPQD
TDCFACRLFNDSGACVRQCPQPLVYNKLTFQLEPNPHTKYQYGGVCVASCPHNFVVDQTS
CVRACPPDKMEVDKNGLKICEPCGGLCPKACEGTGSGSRFQTVDSSNIDGFVNCTKILGN
LDFLITGLNGDPWHKIPALDPEKLNVFRTVREITGYLNIQSWPPHMHNFSVFSNLTTIGG
RSLYNRGFSLLIMKNLNITSLGFRSLKEISAGRIYISANRQLCYHHSLNWTRLLRGPSEE
RLDIKHNRPRRDCVAEGKVCDPLCSSGGCWGPGPGQCLSCRNYSRGGVCVTHCNFLNGEP
REFAHEAECFSCHPECQPMEGTATCNGSGSDACAQCAHFRDGPHCVSSCPSGVLGAKGPI
YKFPDAQNECRPCHENCTQGCNGPDLQDCLGQTQVMISKTHLAMALAVVVGLVVVFVVLS
SIILYWRGRRIQNKRAMRRYLERGESIEPLDPSEKANKVLARIFKETELRKLKVLGSGVF
GTVHKGVWIPEGESIKIPVCIKVIEDKSGRQSFQAVTDHMLAIGSLDHAHIVRLLGLCPG
SSLQLVTQYLPLGSLLDHVRQHRGSLGPQLLLNWGVQIAKGMYYLEEHGMVHRNLAARNV
LLKSTSQVQVADFGVADLLPPDDKQLLHSEAKTPIKWMALESIHFGKYTHQSDVWSYGVT
VWELMTFGAEPYAGLRLAEVPDLLEKGERLAQPQICTIDVYMVMVKCWMIDENIRPTFKE
LANEFTRMARDPPRYLVIKRESGPGIPPGAEPPALTNKELEEVELEPELDLDLDLEAEED
NLATTLGSALSLPVGTLTWPRGSQSLISPSSGYMPMNQSNLGEACQEPVGCGGGERCPRP
ASLHPMPRGRLISESSEGHVTGSEAELQEKVSMCRSRSRSPRPRGDSAYHSQRHSLLTPV
TPLSPPGLEEEDVNGYVMPDAHLKGTPSSREGTLSSVGLNSVLGTEEEDEDEEYEYMNRR
RRHSPPRPPRPSSLEELGYEYMDVGSDLSASLGSTQSCPLHPVPIMPTAGTTPDEDYEYM
NKRRGGGGAGGDYAAMGACPAAEQGYEEMKAFQGPGHHAPQVHYARLKTLRSLEATDSAF
DNPDYWHSRLFPKANAQRT
NT seq
4020 nt
NT seq
+upstream
nt +downstream
nt
atgagggcgaaccgggctctgcaggtgctgggcttcctcctcagcctggcccggggctcc
gaggtgggcaactcgcagtcagtgtgtcccgggactttgaatggtctgagtgtgactggc
gatgctgagaaccagtaccagacactgcacaagcagtacgagaggtgtgaggtggtgatg
gggaacctggagattgtgctcacaggacacaacgctgacctctccttcctgcagtggatt
cgagaagtgaccggctatgtcctcgtggccatgaatgagttctccactctgccactgccc
aatctccgagtggtgcgggggacccaggtgtacgacgggaagtttgccatctttgtcatg
ttgaactacaacaccaactccagccacgctctgcgccagctcggctttacccagctcaca
gagattctgtccgggggcgtgtatattgagaagaatgataaactttgtcacatggacaca
attgactggagggacatcgtgagggaccgagacgccgagatcgtggtgaaggacaatggc
aggagctgtgcgtcgtgtcatgcggtctgcaatgggcgatgctggggtcccggtccaaaa
gactgccagacattgaccaagaccatctgtgcgccgcagtgtaacggtcactgctttggg
cccgaccccaaccagtgctgccatgatgagtgtgcagggggctgctcaggccctcaggac
accgactgctttgcctgccggctcttcaatgacagtggagcctgtgtacgacagtgccca
cagcctcttgtctacaacaagctgacgttccagctggaacccaaccctcacaccaagtat
cagtatggaggagtctgtgtagccagctgtccccataactttgtggtggaccagacgtca
tgtgtcagagcctgtcctcctgacaagatggaagtggataaaaatggactcaagatatgt
gaaccttgtggggggctgtgccccaaagcttgtgagggcaccggctctgggagccgattc
cagactgtggactcgagcaacattgatgggtttgtgaactgcaccaagatcctgggcaac
ctggactttctcatcactggcctcaatggagacccttggcacaagatccctgctttggac
cctgagaagctcaatgtcttccggacagtacgggagatcacgggctacctgaacattcag
tcctggcctccccacatgcacaacttcagtgtcttttccaacctgacgaccatcgggggc
agaagcctctacaaccggggcttctcattgttgatcatgaagaacttgaacataacatct
ctgggcttccgatccttgaaagaaataagtgctgggcgtatctacataagtgccaatcgg
cagctctgctaccaccattctcttaactggaccaggctgcttcgagggccttctgaagag
agactagacatcaagcataatcggccccgcagagactgcgtggcagagggcaaagtgtgt
gacccactctgctcctctgggggatgctggggcccaggccctggtcagtgcctatcctgt
cgaaactacagccgaggaggtgtctgtgtgacccactgcaactttctgaatggggagcct
cgtgagtttgcccatgaggctgaatgcttctcctgtcacccggaatgccagcccatggag
ggcactgccacatgcaatggctcgggctctgatgcttgtgcccagtgtgcccattttcga
gatgggccccactgtgtgagcagctgcccctctggagtgctgggtgccaagggccccatc
tacaagttcccagatgctcagaatgaatgtcggccttgccatgagaactgcacccagggg
tgtaatgggcctgacctgcaagactgtttaggccaaacacaggtgatgatcagcaaaacg
catttggcaatggctttagcagtggtggtaggattggtagtggttttcgtggtcctgagc
agcattatcctctattggcgtgggcgtcggattcagaataagagggctatgaggcgctac
ttggaacggggtgagagcatagagcctctggatcccagtgagaaggctaacaaagtcttg
gccagaatcttcaaggagacagagctgaggaagcttaaagtacttggctcaggcgtcttt
ggaactgtgcacaagggagtgtggattcctgagggtgaatcaataaagatcccagtctgc
attaaagtcattgaggataagagtggacggcaaagttttcaagctgtgacggatcatatg
ctggccattggcagcctagaccatgctcacattgtacggctgctaggactgtgcccaggg
tcatctctgcagcttgtcactcaatacttgcctctgggatccctgctggatcatgtgaga
caacaccgggggtcactggggccacagctgctgctcaattggggagtacaaattgccaag
ggtatgtactaccttgaggagcatggtatggttcataggaacttagctgcccgaaatgtg
ctactaaagtcaaccagtcaggttcaggtggcagattttggggtggctgacctgctgccc
cctgatgataaacagctgctacacagtgaggccaagactccaattaagtggatggccctc
gagagtatccactttgggaaatacacacaccagagcgacgtctggagctatggtgtgaca
gtttgggagctgatgacttttggggcagagccctatgcagggctgcggttggctgaagta
ccagacctgctggagaagggagagcgattggcacagccccagatctgtaccattgatgtc
tacatggtcatggtcaagtgttggatgattgatgagaacattcgcccaacctttaaagaa
ctagccaatgagttcaccaggatggcccgagacccaccacggtatctggtcataaagaga
gagagtggacctggaatcccccctggggcagagccccctgctctgacaaacaaggaactg
gaggaagtagagctggagccagaactagacctagacctggacttggaggcagaggaggac
aacctggcaacaacactaggctctgccctgagcctgccagttggaacacttacttggcca
cgtgggagccagagccttataagtccatcatctgggtatatgcctatgaaccagagtaat
cttggggaagcttgccaggagcctgtaggttgtgggggtggtgaacggtgcccccgtcca
gcctctctgcacccaatgccacggggacgcctgatatcagagtcatctgagggccatgtg
acaggctctgaagctgagctccaggagaaggtgtccatgtgtagaagccggagccggagc
ccgcggccacgtggagacagtgcctaccattcccagcgccacagcctgcttactcctgtc
accccactctccccaccagggttagaggaagaggatgtcaatggttatgtcatgccagat
gcacacctcaaaggtactccatcctcgcgggaaggcacgctttcttctgtgggtctcaat
tctgtcctgggtacggaagaagaagatgaagatgaggagtatgaatacatgaaccggagg
agaaggcacagtccacctcgtcccccaaggccaagttccctcgaggagctgggttatgag
tacatggatgtgggatcagacctcagtgcttccctgggcagcacacagagttgcccgctc
caccctgtgcccatcatgcctactgctggcacaactccagatgaggactatgaatatatg
aataagcgacgtggtggaggaggtgctgggggggattatgcagccatgggggcctgccca
gcagctgaacaagggtatgaagagatgaaagccttccaggggcctggacaccatgctccc
caagtccattatgcccgcctcaaaacgctacgtagcttagaagccactgactctgccttt
gataacccggattactggcatagcaggcttttccccaaggctaatgcccagagaacataa
DBGET
integrated database retrieval system
