KEGG   Plecotus auritus (brown big-eared bat): 308246996
Entry
308246996         CDS       T11911                                 
Symbol
TNF, AC0HY7_013829
Name
(RefSeq) tumor necrosis factor isoform 1
  KO
K03156  tumor necrosis factor superfamily, member 2
Organism
pots  Plecotus auritus (brown big-eared bat)
Pathway
pots01523  Antifolate resistance
pots04010  MAPK signaling pathway
pots04060  Cytokine-cytokine receptor interaction
pots04061  Viral protein interaction with cytokine and cytokine receptor
pots04064  NF-kappa B signaling pathway
pots04071  Sphingolipid signaling pathway
pots04150  mTOR signaling pathway
pots04210  Apoptosis
pots04217  Necroptosis
pots04350  TGF-beta signaling pathway
pots04380  Osteoclast differentiation
pots04612  Antigen processing and presentation
pots04620  Toll-like receptor signaling pathway
pots04621  NOD-like receptor signaling pathway
pots04622  RIG-I-like receptor signaling pathway
pots04625  C-type lectin receptor signaling pathway
pots04640  Hematopoietic cell lineage
pots04650  Natural killer cell mediated cytotoxicity
pots04657  IL-17 signaling pathway
pots04660  T cell receptor signaling pathway
pots04664  Fc epsilon RI signaling pathway
pots04668  TNF signaling pathway
pots04920  Adipocytokine signaling pathway
pots04930  Type II diabetes mellitus
pots04931  Insulin resistance
pots04932  Non-alcoholic fatty liver disease
pots04933  AGE-RAGE signaling pathway in diabetic complications
pots04936  Alcoholic liver disease
pots04940  Type I diabetes mellitus
pots05010  Alzheimer disease
pots05014  Amyotrophic lateral sclerosis
pots05020  Prion disease
pots05022  Pathways of neurodegeneration - multiple diseases
pots05132  Salmonella infection
pots05133  Pertussis
pots05134  Legionellosis
pots05135  Yersinia infection
pots05140  Leishmaniasis
pots05142  Chagas disease
pots05143  African trypanosomiasis
pots05144  Malaria
pots05145  Toxoplasmosis
pots05146  Amoebiasis
pots05152  Tuberculosis
pots05160  Hepatitis C
pots05161  Hepatitis B
pots05163  Human cytomegalovirus infection
pots05164  Influenza A
pots05165  Human papillomavirus infection
pots05166  Human T-cell leukemia virus 1 infection
pots05168  Herpes simplex virus 1 infection
pots05169  Epstein-Barr virus infection
pots05170  Human immunodeficiency virus 1 infection
pots05171  Coronavirus disease
pots05205  Proteoglycans in cancer
pots05310  Asthma
pots05321  Inflammatory bowel disease
pots05322  Systemic lupus erythematosus
pots05323  Rheumatoid arthritis
pots05330  Allograft rejection
pots05332  Graft-versus-host disease
pots05410  Hypertrophic cardiomyopathy
pots05414  Dilated cardiomyopathy
pots05417  Lipid and atherosclerosis
pots05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pots00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    308246996 (TNF)
   04350 TGF-beta signaling pathway
    308246996 (TNF)
   04064 NF-kappa B signaling pathway
    308246996 (TNF)
   04668 TNF signaling pathway
    308246996 (TNF)
   04071 Sphingolipid signaling pathway
    308246996 (TNF)
   04150 mTOR signaling pathway
    308246996 (TNF)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    308246996 (TNF)
   04061 Viral protein interaction with cytokine and cytokine receptor
    308246996 (TNF)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    308246996 (TNF)
   04217 Necroptosis
    308246996 (TNF)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    308246996 (TNF)
   04620 Toll-like receptor signaling pathway
    308246996 (TNF)
   04621 NOD-like receptor signaling pathway
    308246996 (TNF)
   04622 RIG-I-like receptor signaling pathway
    308246996 (TNF)
   04625 C-type lectin receptor signaling pathway
    308246996 (TNF)
   04650 Natural killer cell mediated cytotoxicity
    308246996 (TNF)
   04612 Antigen processing and presentation
    308246996 (TNF)
   04660 T cell receptor signaling pathway
    308246996 (TNF)
   04657 IL-17 signaling pathway
    308246996 (TNF)
   04664 Fc epsilon RI signaling pathway
    308246996 (TNF)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    308246996 (TNF)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    308246996 (TNF)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    308246996 (TNF)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    308246996 (TNF)
   05170 Human immunodeficiency virus 1 infection
    308246996 (TNF)
   05161 Hepatitis B
    308246996 (TNF)
   05160 Hepatitis C
    308246996 (TNF)
   05171 Coronavirus disease
    308246996 (TNF)
   05164 Influenza A
    308246996 (TNF)
   05168 Herpes simplex virus 1 infection
    308246996 (TNF)
   05163 Human cytomegalovirus infection
    308246996 (TNF)
   05169 Epstein-Barr virus infection
    308246996 (TNF)
   05165 Human papillomavirus infection
    308246996 (TNF)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    308246996 (TNF)
   05135 Yersinia infection
    308246996 (TNF)
   05133 Pertussis
    308246996 (TNF)
   05134 Legionellosis
    308246996 (TNF)
   05152 Tuberculosis
    308246996 (TNF)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    308246996 (TNF)
   05144 Malaria
    308246996 (TNF)
   05145 Toxoplasmosis
    308246996 (TNF)
   05140 Leishmaniasis
    308246996 (TNF)
   05142 Chagas disease
    308246996 (TNF)
   05143 African trypanosomiasis
    308246996 (TNF)
  09163 Immune disease
   05310 Asthma
    308246996 (TNF)
   05322 Systemic lupus erythematosus
    308246996 (TNF)
   05323 Rheumatoid arthritis
    308246996 (TNF)
   05321 Inflammatory bowel disease
    308246996 (TNF)
   05330 Allograft rejection
    308246996 (TNF)
   05332 Graft-versus-host disease
    308246996 (TNF)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    308246996 (TNF)
   05014 Amyotrophic lateral sclerosis
    308246996 (TNF)
   05020 Prion disease
    308246996 (TNF)
   05022 Pathways of neurodegeneration - multiple diseases
    308246996 (TNF)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    308246996 (TNF)
   05418 Fluid shear stress and atherosclerosis
    308246996 (TNF)
   05410 Hypertrophic cardiomyopathy
    308246996 (TNF)
   05414 Dilated cardiomyopathy
    308246996 (TNF)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    308246996 (TNF)
   04940 Type I diabetes mellitus
    308246996 (TNF)
   04936 Alcoholic liver disease
    308246996 (TNF)
   04932 Non-alcoholic fatty liver disease
    308246996 (TNF)
   04931 Insulin resistance
    308246996 (TNF)
   04933 AGE-RAGE signaling pathway in diabetic complications
    308246996 (TNF)
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    308246996 (TNF)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:pots04052]
    308246996 (TNF)
   00536 Glycosaminoglycan binding proteins [BR:pots00536]
    308246996 (TNF)
Cytokines and neuropeptides [BR:pots04052]
 Cytokines
  Tumor necrosis fators
   308246996 (TNF)
Glycosaminoglycan binding proteins [BR:pots00536]
 Heparan sulfate / Heparin
  Cytokines
   308246996 (TNF)
SSDB
Motif
Pfam: TNF
Other DBs
NCBI-GeneID: 308246996
NCBI-ProteinID: XP_080521611
LinkDB
Position
4:complement(<102073301..>102075037)
AA seq 231 aa
MSTESMIRDVELAEEAIPKKAGGPQGSRRCLCLSLFSFLLVAGATTLFCLLHLGVIGPQR
EEQFPMGGLPLAQTLGLSSRTPGDKPVAHVVANQQTVGQLQWQSKVANALLANGVNLTDN
QLVVPLNGLYLIYSQVLFKGKGCPHTPLLLTHTVSRFAVSYKVKINLLYAIKSPCQRETP
EGTEAMPWYEPIYLGGVFQLDKGDRLSAEINLPDYLDFSESGQVYFGIAAL
NT seq 696 nt   +upstreamnt  +downstreamnt
atgagcactgaaagcatgatccgcgacgtggagctggcggaggaggcgatccccaagaag
gcagggggcccccagggctccagacggtgcttgtgcctcagcctcttctccttcctcctc
gtggcaggagccaccacactcttctgcctgctgcacttgggggtgatcggcccccagagg
gaagagcagttccccatgggcggcctcccgctggcccagaccctcggattatcttctcga
accccaggtgacaagcctgtggcccatgttgtagcaaaccagcaaactgtggggcagctg
cagtggcagagcaaggtggccaatgcactcttggccaatggtgtcaacctgacagacaac
cagctggtggtgccattgaatgggctgtacctgatctactcccaagtcctcttcaagggc
aaaggctgccctcacacccccctcctgctcacccacaccgtcagccgctttgccgtctcc
tacaaggtgaagatcaacctcctctatgccatcaagagcccctgccagcgggagacccca
gaggggactgaggccatgccctggtacgagcccatctacctgggaggggtcttccagctg
gacaagggtgatcggctcagtgccgagatcaacctgcctgactatctcgatttttcagag
tccgggcaggtctactttgggatcgctgccctgtga

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