Penicillium oxalicum: POX_c03793
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Entry
POX_c03793 CDS
T09521
Name
(RefSeq) Histidine biosynthesis trifunctional protein
KO
K14152
phosphoribosyl-ATP pyrophosphohydrolase / phosphoribosyl-AMP cyclohydrolase / histidinol dehydrogenase [EC:
3.6.1.31
3.5.4.19
1.1.1.23
]
Organism
pou
Penicillium oxalicum
Pathway
pou00340
Histidine metabolism
pou01100
Metabolic pathways
pou01110
Biosynthesis of secondary metabolites
pou01230
Biosynthesis of amino acids
Module
pou_M00026
Histidine biosynthesis, PRPP => histidine
Brite
KEGG Orthology (KO) [BR:
pou00001
]
09100 Metabolism
09105 Amino acid metabolism
00340 Histidine metabolism
POX_c03793
Enzymes [BR:
pou01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.23 histidinol dehydrogenase
POX_c03793
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.19 phosphoribosyl-AMP cyclohydrolase
POX_c03793
3.6 Acting on acid anhydrides
3.6.1 In phosphorus-containing anhydrides
3.6.1.31 phosphoribosyl-ATP diphosphatase
POX_c03793
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Gene cluster
GFIT
Motif
Pfam:
Histidinol_dh
PRA-CH
PRA-PH
Motif
Other DBs
NCBI-GeneID:
74436087
NCBI-ProteinID:
XP_049970238
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Position
III:complement(886977..889756)
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AA seq
868 aa
AA seq
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MATPFLVAYPSNPTSGLSLKQIAYFGRVLVKVSTLAEVEQFLRQNFRQLDVYVDATAISS
TGDLVDILNAGAAKILITLDQLTVLSQEQSVPSSRLLVSAATESQIDSLQQWIASDATER
NDVSVATPAVSTAASKLNISTDSSRLFTVLDNQAVSEDAIGEVAQKGAIAILSSETLTVE
RDAAGQISAAKLIAARAVTDQSNGLYATSVTDERGSCLGVVWSSDESIAEALRTGTGVYQ
SRKRGLWYKGQSSGDTQELIRIGYDCDADCLVFVVKQTGRGFCHLGTDSCFGTSTGLSRL
QKTLLARKADAPAGSYTARLFNEPKLVEAKIMEEAEELCRATTKEEIAFEAADLFYFALT
KCTAAGVSLEDIERNLDLKSLKVKRRKGDAKGPWAEKAGLAPASTTEAASAPAPAPAPVV
EQETRMEMKRVYTSETPITEVKEFLKRPAQKSNDAIVALVKPIIQDVRDGGDAAVLKYTH
KFERATSLTSPVIKAPFPAELMKLTPDVQEAIDVSIGNIQRFHTAQKSSNDTLRMETMPG
VVCSRFSRPIERVGLYVPGGTAVLPSTAMMLGVPAMVAGCQKIVLASPPRADGSISPEIV
YVAHKVGAESIVLAGGAQAVAAMAYGTESVTKVDKILGPGNQFVTAAKMFVSNDTSAGVS
IDMPAGPSEVLVIADKTANPAFVASDLLSQAEHGVDSQVILIAVDLNEEQLRAIEDEVDT
QAKALPRVDIVRGSLAHSVTFVVRDINEAMILSNEYAPEHLILQVDQPEAVVEQVFNAGS
VFIGPWTPESVGDYSAGVNHSLPTYGYAKQYSGVNLGSYLKHITSSNLTADGLLKLAKTV
ETLAAVEGLDAHKRAVSIRVAQMNKDRL
NT seq
2607 nt
NT seq
+upstream
nt +downstream
nt
atggccacacccttcctggtcgcctacccctccaaccccacctccggcctctctctaaag
cagattgcctactttggccgagtgctggtcaaggtgtcaactcttgcggaggtggagcag
ttcttgcgccagaatttcagacagctcgatgtctacgtcgatgcgacagccatctcctcc
accggagatctcgtggatatcctcaatgccggggccgccaagattctcatcactctggac
caattgaccgtcctttcccaggagcagtccgtcccctcttcaaggctactggtctccgcc
gccacagaatcccagatcgattccttgcagcaatggattgcttcagacgccaccgaacgg
aacgatgtcagcgtggccacacccgcggtttccactgcggcgagcaagttgaacatcagt
acagactcatctcgcctgttcacagtgttggataaccaggctgtttctgaggatgccatc
ggcgaggtcgcacaaaagggagccattgccatcctgtcttcggagacattgactgtggag
cgtgatgcggcaggtcagatctctgcggccaagttgattgccgcgcgcgcagtgaccgac
cagtcaaacggtctctatgctacatccgtgacagacgagcgaggctcatgtctcggagtg
gtctggagcagtgacgagagtattgcagaggcgctccgcaccggaaccggggtataccag
agtcggaagcgtggtctgtggtacaagggtcaatccagtggcgacactcaggagttgatt
cgcattggctatgactgtgacgcagactgcctggtctttgtggtgaagcagactggacga
ggtttctgccaccttggcaccgactcgtgttttggcacctccaccggcctgtcgcgtctt
caaaagacccttctcgcccgcaaggccgatgctccggctggatcgtacactgctcgcctg
ttcaatgaacccaagctcgtcgaagctaaaatcatggaggaggctgaggagctgtgtcga
gccacgaccaaggaggagatcgcttttgaggctgccgatctcttctactttgccctgacc
aagtgtacggccgctggcgtctctttggaggacatcgagcgcaacctggacctcaagagc
ctcaaggtgaagcggcgcaagggcgacgccaagggtccttgggccgagaaggctggcctg
gcgccggcctcgaccacggaagccgcctcagcgcctgctcccgcccctgctcccgtcgtt
gagcaagaaacgcgcatggagatgaagcgtgtctatacttccgaaacccccatcaccgag
gtcaaggaattcttgaagcgtcctgcgcaaaagtccaacgatgccattgtggcgttggta
aagcccatcatccaggatgtgcgcgatggcggcgacgctgctgtcctcaagtacacccac
aagtttgagagggcgacctcgctcacctcgcctgtgatcaaggctcctttccccgccgag
ctgatgaagctaacacccgatgtgcaagaggccatcgacgtgagcatcggcaacatccag
cgattccacaccgcgcagaagagcagcaatgataccctgaggatggagaccatgcccggc
gtcgtttgctctcgcttctcgcggccgattgagcgcgtcggattgtatgtccccggcggc
acggccgtgctgccttccaccgctatgatgctgggtgttccagccatggttgccggctgc
cagaagatcgtgcttgcctcccctccccgggcggacggtagcatttcacccgagatcgtc
tacgtcgctcacaaggtcggtgcggagagcattgttttggccggtggtgcccaggccgtg
gctgcgatggcttacggcaccgagtccgtcaccaaggtcgacaagatccttggccctggc
aaccagtttgtgactgcggcgaagatgtttgtctccaacgacacctctgccggtgtgagc
attgacatgcctgccggccctagtgaggttcttgtcattgccgataagaccgccaatccc
gcctttgttgcctccgacctcttgagccaggctgagcacggtgttgactctcaggtcatc
ctgatcgccgtcgatctcaatgaggaacagctgcgggcaattgaggatgaggttgacacg
caggctaaggcgcttccccgagtggacattgtccgcgggtctctggcccactcggtcacc
ttcgtggtccgtgatatcaacgaagccatgattctcagcaatgagtatgcccctgagcac
ttgatcctccaagtcgatcagccagaggccgtcgtcgagcaagtcttcaatgctggcagc
gtgttcatcggtccctggacccccgagagcgtcggtgactactctgccggtgtgaaccac
tctctccccacctacggctacgccaagcaatactccggtgtcaaccttggctcgtatctc
aagcacatcacaagctctaacctcactgcggatggtctgctgaagctcgccaagacggtc
gagaccctggccgccgttgaaggcctagacgcccacaagcgggctgtcagcatccgcgtt
gcgcagatgaacaaggaccgcttgtaa
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