Komagataella phaffii: PAS_chr1-4_0421
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Entry
PAS_chr1-4_0421 CDS
T01092
Name
(RefSeq) Homocitrate synthase isozyme, catalyzes the condensation of acetyl-CoA and alpha-ketoglutarate
KO
K01655
homocitrate synthase [EC:
2.3.3.14
]
Organism
ppa
Komagataella phaffii
Pathway
ppa00300
Lysine biosynthesis
ppa00620
Pyruvate metabolism
ppa01100
Metabolic pathways
ppa01110
Biosynthesis of secondary metabolites
ppa01210
2-Oxocarboxylic acid metabolism
ppa01230
Biosynthesis of amino acids
Module
ppa_M00030
Lysine biosynthesis, AAA pathway, 2-oxoglutarate => 2-aminoadipate => lysine
ppa_M00433
Lysine biosynthesis, 2-oxoglutarate => 2-oxoadipate
Brite
KEGG Orthology (KO) [BR:
ppa00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
PAS_chr1-4_0421
09105 Amino acid metabolism
00300 Lysine biosynthesis
PAS_chr1-4_0421
Enzymes [BR:
ppa01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.14 homocitrate synthase
PAS_chr1-4_0421
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Motif
Pfam:
HMGL-like
HCS_D2
Motif
Other DBs
NCBI-GeneID:
8197009
NCBI-ProteinID:
XP_002490551
UniProt:
C4QYE7
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Position
1:2177615..2178952
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AA seq
445 aa
AA seq
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MNSSNSKSFVMSETNGQTNGSSNGAQPQQRNPYGPHPSDFLSNVSSFQLIESTLREGEQF
ANAFFTTEKKIEIAKALDDFGVDYIELTSPVASEQSRSDCEAICKLGLKAKILTHIRCHM
DDARVAVETGVDGVDVVIGTSQFLRQFSHGKDMSYITNQAIEVIEFVKSKGIEIRFSSED
SFRSDIVDLLNIYRTVDKIGVNRVGIADTVGCANPRQVYELVKTLKSVVHCDIECHFHDD
TGCAIANAYTALEAGAKLIDVSVLGIGERNGITPLGGLMARMIAADRDYVLSKYKLHKLR
DLETLVAEAVQVNIPFNNPITGFCAFTHKAGIHAKAILANPSTYEILQPSDFGLTRYIHF
ANRLTGWNAIKSRVDQLNLHLTDAQCKEVTAKIKKMGDIRPLNIDDVDSIIKDFHADITT
PAFPPVATNNDEDVEPATKKQRLDQ
NT seq
1338 nt
NT seq
+upstream
nt +downstream
nt
atgaatagtagtaacagtaagagctttgtaatgagtgaaacgaacggtcaaactaatggc
tcctccaatggagcccaacctcagcaacgcaatccatacggacctcacccatctgacttc
ctttcaaatgtttctagcttccagttgatagagtcaaccttgagagaaggtgagcaattt
gccaatgctttcttcaccacagagaaaaagattgaaattgccaaggcgctggacgacttt
ggagtggattacatcgagttgacctctcctgtagcttctgagcagtcaagatccgactgt
gaagcaatctgcaaattaggcctcaaggctaagatcttaactcatattagatgccatatg
gacgatgctagagtggctgtggagactggtgtggatggtgttgatgttgttattggtact
tctcaatttttgagacaatttagtcacggaaaggacatgtcctacattaccaaccaagca
atcgaagtgatcgaatttgtcaagtccaagggaatcgaaatcagattttcctctgaagat
tccttccgttctgacatcgtcgaccttttgaacatctacagaaccgttgataagatcggt
gtgaacagagttggtatagctgacaccgtcggttgtgccaacccaagacaagtttacgag
ctggttaagacccttaaatctgtcgttcactgcgatattgagtgccatttccacgatgac
actggttgtgctatagcaaacgcttacacggcgttggaagctggtgccaaacttatcgac
gtctccgtgttgggtatcggtgagagaaacggtatcacccctcttggtggtttgatggct
agaatgattgccgcagacagagattacgttttatccaaatacaaactgcataaactgagg
gacttagaaaccttagttgccgaggctgttcaagtgaatatcccattcaacaacccaatt
actggtttctgtgctttcactcacaaagccggtattcatgccaaggccattctagccaat
ccatccacatacgagatcttgcaaccatctgactttggtttaactaggtatattcatttt
gccaacagattaactggctggaatgctatcaaatctcgtgtcgaccagttgaacttgcat
ttgactgatgctcagtgcaaggaggtcactgccaaaattaaaaagatgggagacatcaga
ccattgaacattgacgatgttgactctatcattaaggatttccatgctgatatcaccacc
ccagcattccctcctgttgctactaacaatgacgaggatgttgagcccgccaccaagaaa
caaagattagatcaatag
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