Komagataella phaffii: PAS_chr2-1_0089
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Entry
PAS_chr2-1_0089 CDS
T01092
Name
(RefSeq) Component of the mitochondrial alpha-ketoglutarate dehydrogenase complex, which catalyzes a key step
KO
K00164
2-oxoglutarate dehydrogenase E1 component [EC:
1.2.4.2
]
Organism
ppa
Komagataella phaffii
Pathway
ppa00020
Citrate cycle (TCA cycle)
ppa00785
Lipoic acid metabolism
ppa01100
Metabolic pathways
ppa01110
Biosynthesis of secondary metabolites
ppa01200
Carbon metabolism
ppa01210
2-Oxocarboxylic acid metabolism
Module
ppa_M00009
Citrate cycle (TCA cycle, Krebs cycle)
ppa_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
ppa00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
PAS_chr2-1_0089
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
PAS_chr2-1_0089
Enzymes [BR:
ppa01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
PAS_chr2-1_0089
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Motif
Pfam:
E1_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-GeneID:
8198485
NCBI-ProteinID:
XP_002490970
UniProt:
C4QZL6
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Position
2:complement(156825..159830)
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AA seq
1001 aa
AA seq
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MLKSFKGISSRSSILRNAPRRLIQTRLLATDSFLQSNNANYIDEMYEQWSKDPSSVHSSW
NAYFKNLDQGVPPSRAFQAPPTLIPQPAGGIPNLVPVGNASGNSNVLTHLKAQLLVRAYQ
VRGHQKAKIDPLGISFGDDKSKPVPKELTQEFYGFTEADLDTEITLGPGILPKFAEAGHP
TMKLRDIIKACEKIYCSSYGVEYVHIPSREKCDWLRERIEIPTPYKYSVDEKRQILDRLI
WSCSFENFLSSKFPNDKRFGVEGAESVIPGMKALIDTAVENGVEDVVIGMAHRGRLNMLS
NVVRKPNESIFSEFTGSKDFDEGSGDVKYHLGMNYVRPTTSGKKVHLSLVANPSHLEAED
PVVLGRTRAIQHYKGDVGEFNKAMGILVHGDAAFAGQGIVYETMGFAALPAYSTGGTIHI
IINNQIGFTTDPRFARSTPYPSDIAKSINAPILHVNADDVESVIFNFQLAAEWRQTFHSD
VILDVVGYRKYGHNETDQPSFTQPLMYQKIAEKKQVLDIYVDKLIKEGSFTLDDINEHKQ
WVWNTLEEAFTKSVEYKPTSREWLTTPWEGFKSPKELASEVLPHLPTSVERGVVERIGDT
ISSWPEGFEVHRNLKRILKNRKDSIQKGEGIDWSTGEALAFGSLVIEGYHVRISGQDVER
GTFSQRHAVLHDQNSEKVYIPLKHLSKVQSDFGISNSSLSEYGCMGFEYGYSLTSPDALV
MWEAQFGDFANTAQVIIDQFLAAGESKWKQRSGVVLSLPHGYDGQGSEHSSARLERYLQL
CNEDPRVYPSPEKLERQHQDCNMQVAYPTTPANLFHLLRRQMHRQFRKPLILLFSKKLLR
HPLARSNIEDFIGESSFQWIIEDSELGKTINDKEGIKRLVLCSGQVHSSLHKKRADIGDK
ETAVLKIEQLHPFPFEQLKNAIDSYPSLDEIVWCQEEPLNMGSYAFSAPRIVTVLEQTEK
YKDYNLRYAGRNPAAAVAVGTKSMHVAQEEAFLDDVFQIQN
NT seq
3006 nt
NT seq
+upstream
nt +downstream
nt
atgttaaaatcattcaaaggcatctcctccaggagcagcatcttgaggaatgctcccaga
cgattgatccagaccagattattggccaccgattcatttttgcagtcaaataacgccaac
tacattgatgaaatgtacgaacaatggtccaaggacccgtcatctgttcactcgtcgtgg
aacgcttatttcaagaacttagaccagggcgtccccccatctcgtgccttccaagcacca
ccaaccttgattccacagccagctggtggtattcccaacttggtgcctgtaggtaacgca
agtggcaactccaatgttttgacgcatttgaaagctcagctgttggttcgtgcttatcag
gtcagaggtcaccaaaaggctaaaattgaccccttgggaatctcctttggtgacgacaag
tccaaaccagtgccaaaggaactgactcaggaattttatggttttaccgaggcagacttg
gacactgagattactctcggaccaggtattcttcctaagttcgccgaggctggacacccc
acaatgaaactacgtgatattattaaggcatgtgagaaaatctactgttcatcctacggt
gttgagtatgttcatatcccttcaagagagaagtgtgactggctcagagagagaattgaa
attccaaccccttacaagtactccgtcgatgagaagagacaaattcttgacagacttatc
tggtcttgttcttttgaaaactttctgagttccaaattccccaacgacaagagatttggt
gttgaaggtgccgagtctgtcattccaggtatgaaggctctgatcgacactgccgttgaa
aacggtgttgaggatgtagtcattggtatggcccaccgtggtcgtctgaacatgttgtca
aacgttgtcagaaaacccaatgagtctatcttctccgagttcactggttctaaagatttc
gatgaaggatctggtgacgtgaaataccatttgggtatgaattacgttcgtccaactaca
tccggtaagaaagtccacctttccttggttgccaatccttctcatttggaggcagaagat
cccgttgttttgggtagaactagagctatccagcactacaagggagatgttggtgaattc
aacaaggctatgggtattttggtccacggtgatgctgcttttgccggtcagggtatcgtt
tacgaaactatgggtttcgctgccttaccagcttattctactggtggtaccatccatatc
attattaacaaccaaattggtttcacaacggatccacgttttgctagatccactccttac
ccatctgatattgccaaatcaatcaatgctccaattttgcatgttaatgctgacgacgtt
gagtcagttattttcaacttccaattggcagctgaatggagacagactttccactccgat
gttattttggatgttgttggctaccgtaaatacggtcacaacgaaactgaccagccttct
ttcacccagcctttgatgtaccagaagattgctgagaagaagcaagtgctcgatatttac
gttgacaagttaatcaaggagggatcattcactctagatgacatcaatgaacacaagcaa
tgggtttggaacacattagaagaagcatttaccaagtctgttgagtacaaacccacctcc
agagaatggttaacaacaccttgggagggattcaagtctccaaaagaattggcttctgaa
gtattgcctcacttgccaacctctgtggaaaggggcgtagttgagagaatcggtgacacc
atctcttcttggcctgaaggatttgaggttcacagaaatttgaagcgtatcttaaagaat
agaaaagattccattcaaaaaggtgagggtattgactggtctactggtgaagctcttgcc
tttggaagtttggttattgaaggttatcatgtcagaatttccggccaagatgttgaaaga
ggaaccttctcccaacgtcacgccgttcttcacgaccaaaactccgaaaaagtctacatt
cctctcaaacatctaagtaaagttcaatccgacttcggtatttctaactcttccctttca
gaatacggatgtatgggttttgagtatggttactcactgacctcacctgatgctttggtt
atgtgggaagctcaatttggtgacttcgctaacactgctcaagttattattgatcaattc
cttgccgctggtgaatctaaatggaagcagagatccggtgttgtcctttctttgccccat
ggttacgatggtcaaggttccgagcactcttctgcccgtttagaacgttacttgcagctt
tgtaatgaagacccaagagtttatccatctcctgagaagctggagagacaacatcaagat
tgtaacatgcaagttgcttatccaaccactccagccaatctgttccatctgttgagacgt
caaatgcaccgtcaattcagaaagcctttaattttgctcttttcgaagaagttgttgcgt
cacccattggccagatctaacattgaagatttcattggagaatctagtttccaatggata
attgaggattctgagctgggcaaaaccatcaatgacaaggagggtattaagcgattagtt
ctttgttctggtcaagttcattcttctttgcacaagaagcgtgctgatattggcgacaaa
gagaccgctgtattgaagattgaacaactgcacccattcccattcgaacaattgaagaac
gccattgatagctacccatctttggatgagattgtttggtgtcaggaagaaccattgaac
atgggttcttacgcattttctgcaccaaggatagtaaccgtattggaacagaccgagaag
tacaaggattacaacctgcgctatgctggtagaaacccagcagctgctgttgccgttggt
actaagtcgatgcacgttgctcaagaagaggctttcttggacgatgtcttccaaatccaa
aattaa
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