| Entry |
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| Symbol |
OGDH, sucA
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| Name |
2-oxoglutarate dehydrogenase E1 component [EC: 1.2.4.2]
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| Pathway |
| map01110 | Biosynthesis of secondary metabolites |
| map01120 | Microbial metabolism in diverse environments |
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| Module |
| M00009 | Citrate cycle (TCA cycle, Krebs cycle) |
| M00011 | Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate |
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| Disease |
| H01022 | Diseases of the tricarboxylic acid cycle |
| H02006 | Alpha-ketoglutarate dehydrogenase complex deficiency |
| H02562 | Yoon-Bellen neurodevelopmental syndrome |
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| Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
K00164 OGDH, sucA; 2-oxoglutarate dehydrogenase E1 component
Enzymes [BR:ko01000]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
K00164 OGDH, sucA; 2-oxoglutarate dehydrogenase E1 component
Enzymes of 2-oxocarboxylic acid metabolism [br01601.html]
2-Oxoacid oxidizing enzymes
K00164
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| Other DBs |
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| Genes |
» show all
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| Reference |
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| Authors |
Shi Q, Chen HL, Xu H, Gibson GE |
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| Title |
Reduction in the E2k subunit of the alpha-ketoglutarate dehydrogenase complex has effects independent of complex activity. |
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| Journal |
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| Sequence |
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| Reference |
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| Authors |
Repetto B, Tzagoloff A |
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| Title |
Structure and regulation of KGD1, the structural gene for yeast alpha-ketoglutarate dehydrogenase. |
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| Journal |
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| Sequence |
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| LinkDB |
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