Komagataella phaffii: PAS_chr2-2_0137
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Entry
PAS_chr2-2_0137 CDS
T01092
Name
(RefSeq) Cystathionine beta-synthase, catalyzes the synthesis of cystathionine from serine and homocysteine
KO
K01697
cystathionine beta-synthase [EC:
4.2.1.22
]
Organism
ppa
Komagataella phaffii
Pathway
ppa00260
Glycine, serine and threonine metabolism
ppa00270
Cysteine and methionine metabolism
ppa00670
One carbon pool by folate
ppa01100
Metabolic pathways
ppa01110
Biosynthesis of secondary metabolites
ppa01230
Biosynthesis of amino acids
Module
ppa_M00338
Cysteine biosynthesis, homocysteine + serine => cysteine
Brite
KEGG Orthology (KO) [BR:
ppa00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
PAS_chr2-2_0137
00270 Cysteine and methionine metabolism
PAS_chr2-2_0137
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
PAS_chr2-2_0137
Enzymes [BR:
ppa01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.22 cystathionine beta-synthase
PAS_chr2-2_0137
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Motif
Pfam:
PALP
CBS
PTCB-BRCT
Motif
Other DBs
NCBI-GeneID:
8198715
NCBI-ProteinID:
XP_002492068
UniProt:
C4R2R4
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Position
2:2130670..2132175
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AA seq
501 aa
AA seq
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MSDNNQPLPPVSNSILEHIGKTPLVKLNRIPKILNLKPQVYAKVELFNSGGSIKDRIALR
MVEQAEKEGRIKPGYTLIEPTSGNTGIGLALVGAVKGYRTIITLPEKMSNEKVAVLKALG
AEIIRTPTEAAWDSPESHIGVARRLEKEIPNAVILDQYGNVNNPDAHFYTTGAEIWDQTN
GKVTHVVAGAGTGGTITGIAKFLKSKNPNIQIIGADPHGSILALPESLNTSNEQYKVEGI
GYDFIPEVLDREIVDTWYKTDDKDSFKLARQLISEEGILVGGSSGSALSAAVKIINDAKL
DESAVVVVVCPDSIRSYLTKFADDDWMKLNGFTEDEPAPLKRKSSFSKDTLSSYTIKDLA
LKPVVSVTIDDSIESTINILQTKGFDQLPVLKNDKLAGIVTLSQLLRLLSNKKIHLTSKV
ESAYFDFSKLENFEKSYNINKESTNKRREYQKITTSTTLAKLNKFFETSSAAIVENDKGQ
PIHIVSKVDLLSFLASKGEFN
NT seq
1506 nt
NT seq
+upstream
nt +downstream
nt
atgtcagacaacaaccaacctttgccaccggtttccaactccattctggagcacattgga
aagactccacttgttaaacttaacagaatacccaaaattcttaatttgaaaccacaggtt
tatgctaaagttgaactgttcaactcaggtggttccatcaaggaccgtattgctctgaga
atggttgagcaagctgagaaagagggtagaatcaagccagggtacacgctaattgagcca
acgtcaggtaacactggtattggtctggcattagtaggtgcagtcaagggctacagaact
attatcactcttccagagaaaatgtctaatgaaaaagttgctgtgctgaaagctctcggg
gctgaaattataagaactccaaccgaggctgcttgggattccccagagtctcacattggt
gttgcaagaaggttggagaaagaaattccaaatgctgtaatcttagaccagtatggtaat
gttaacaatccagatgcccatttctacaccactggtgcggaaatctgggatcagactaat
ggtaaagttacccacgttgttgctggtgcaggaactggaggtacgattacaggtattgcc
aaatttttgaagtctaaaaaccctaatattcaaattatcggtgctgatcctcatggttcc
attctagctcttcctgaatcattgaacactagtaatgagcaatacaaagttgaaggtatt
gggtatgactttatcccagaagttttggatagagaaattgtggacacttggtacaaaaca
gatgataaggattccttcaagctggccaggcaattgatttctgaagaaggaattctagtt
ggaggatcttccggctctgcgctttctgctgctgttaaaataatcaatgatgccaagctt
gatgaaagtgctgtagttgttgtcgtttgtccagacagtatcagatcttatctaaccaag
ttcgctgatgatgactggatgaaactcaatggattcactgaagacgagcctgcacctctc
aaaaggaagtccagcttttcaaaggacactctgtcgtcctatacgatcaaagatttggcg
ctcaaacctgtggtctctgtcaccattgacgattcaattgaatccacaattaatatcctt
caaaccaagggttttgatcagttaccagtgttgaagaacgataagcttgctggtattgtc
actctgtctcaattgttacgattactttctaataagaagattcatcttacttccaaggta
gaatctgcctactttgatttttccaagcttgaaaactttgaaaaatcttacaacattaac
aaggagtcaacaaacaagagaagagaataccagaagatcactactagcaccacgctggcc
aaattgaacaagttttttgagaccagttcagctgctatagtagaaaatgataagggtcaa
ccgatccacatcgtttccaaggttgatctgctttctttcttagcctccaaaggagagttt
aattaa
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