Panthera pardus (leopard): 109247962
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Entry
109247962 CDS
T06062
Symbol
JAK3
Name
(RefSeq) LOW QUALITY PROTEIN: tyrosine-protein kinase JAK3
KO
K11218
Janus kinase 3 [EC:
2.7.10.2
]
Organism
ppad
Panthera pardus (leopard)
Pathway
ppad04062
Chemokine signaling pathway
ppad04151
PI3K-Akt signaling pathway
ppad04217
Necroptosis
ppad04550
Signaling pathways regulating pluripotency of stem cells
ppad04630
JAK-STAT signaling pathway
ppad04658
Th1 and Th2 cell differentiation
ppad04659
Th17 cell differentiation
ppad05161
Hepatitis B
ppad05162
Measles
ppad05166
Human T-cell leukemia virus 1 infection
ppad05169
Epstein-Barr virus infection
ppad05200
Pathways in cancer
ppad05203
Viral carcinogenesis
ppad05223
Non-small cell lung cancer
ppad05340
Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:
ppad00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
109247962 (JAK3)
04151 PI3K-Akt signaling pathway
109247962 (JAK3)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
109247962 (JAK3)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
109247962 (JAK3)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
109247962 (JAK3)
04659 Th17 cell differentiation
109247962 (JAK3)
04062 Chemokine signaling pathway
109247962 (JAK3)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
109247962 (JAK3)
05203 Viral carcinogenesis
109247962 (JAK3)
09162 Cancer: specific types
05223 Non-small cell lung cancer
109247962 (JAK3)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
109247962 (JAK3)
05161 Hepatitis B
109247962 (JAK3)
05162 Measles
109247962 (JAK3)
05169 Epstein-Barr virus infection
109247962 (JAK3)
09163 Immune disease
05340 Primary immunodeficiency
109247962 (JAK3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ppad01001
]
109247962 (JAK3)
Enzymes [BR:
ppad01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
109247962 (JAK3)
Protein kinases [BR:
ppad01001
]
Non-receptor tyrosine kinases
JAK family [OT]
109247962 (JAK3)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
SH2_1
FERM_F1
Jak1_Phl
ABC1
Kdo
Kinase-like
FERM_C_FAK1
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
109247962
NCBI-ProteinID:
XP_019272779
LinkDB
All DBs
Position
Unknown
AA seq
1125 aa
AA seq
DB search
MAPPSEETPLIPQRSCSLSSSEAGALHVLLPPRGPGPPQRLSFSFGDHSAEELCVWAAKA
SGILPVYHSLFALATEDLSYWYPPSHIFSVEDASTQVLLYRLRFYFPNWFGLEKCHRFGL
RKDLASAVLDLPVLEHLFAQHRNDLVSGRLAVGLSLKEQGECLSLAVLDLARMAREQAQQ
PEELLKTVSYKACLPPDLRDLIQGLSFVTRKRIRRTVRRALGRVTACQADRHSLMAKYIM
DLERLDPARAAETFLVSLPGAAGGQDAPGLLRVAGDSGIHWSPGGHEALQPFCDFPEIVD
ISIKQAPRVGPAGEHRLVTVTRTDNQILEAEFPGLPAALSFVALVDGYFRLTSDSRHFFC
KEVAPPRLLEEVAEQCHGPITLDFAINKLKTRGSLPGSYVLRRSPQDFDSFLLTVCVQTP
LGPDYKGCLIRCDPTGTFSLAGLGRPHSSLRELLAACWDAGLHVDGVALNLTSCCAPRPK
EKSNLIVVRRGCSAPTSSLVWPQSQCQLSQMTFHKIPADSLEWHENLGHGSFTKIYRGCR
HEAVDGEARETEVLLKVMDAKHRNCMESFLEAASLMSQVSYQHLVLLHGVCMAGDSVMVQ
EFVRLGALDTYLRKSGPLVPASWKLQVIKQLAYALNYLEDKGLPHGNVSARKVLLAREGA
DGNLPFIKLSDPGVSPTVLSLEMLTDRIPWVAPECLQEARTLGLEADKWGFGATVWEVFS
GIPMPISTLDPAKKLQFYEERQHLPAPKWMELATLIQQCMAYEPGQRPSFRAIIRDLNSL
ITSDYELLSDPTPGALAPRDGLWNGAQLYACQDPTIFEERHLKYISQLGKGNFGSVELCR
YDPLGDNTGALVAVKQLQHSGPDQQRDFQREIQILKALHSDFIVKYRGVSYGPGRQSLRL
VMEYLPSGCLRDFLQRHRARLDASRLLLYASQICKGMEYLGSRRCVHRDLAARNILVESE
THVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSFGVVLYEL
FTYGSKNCSPSAEFLRMMGCERDVPALCRLLELLAEGQRLPAPPACPGEVHELMKLCWAP
SPQDRPTFSALGPQLDTLWSGSRGVAXSEVATLWASRFTEIPTGQ
NT seq
3378 nt
NT seq
+upstream
nt +downstream
nt
atggcgcctccaagtgaggagacacccctgatccctcagcgttcctgcagcctctcatct
tcagaggctggtgccctgcacgtgctgctgccccctcggggccccggacccccacaacgc
ctgtccttctcctttggggaccattcagctgaagaactatgtgtttgggctgctaaggcc
agtggcatcctgcctgtgtaccactccctctttgctctggccacggaggacctgtcctac
tggtaccccccgagccacatcttctccgtggaggatgcaagcacccaagtcctgctctac
aggctccgcttttacttccccaactggtttgggttggagaaatgccaccgcttcgggctg
cggaaggacttggccagtgccgtccttgacctgccagtcctggagcatctcttcgcccag
caccgaaatgacctggtgagcggccgcctcgccgtgggcctcagtctcaaggagcagggt
gaatgtctcagcctggcagtgctggacctggctcggatggcccgtgagcaggctcagcag
cctgaggagctgctgaagaccgtcagctacaaggcctgcctgccccccgatctgcgcgac
ctgatccagggcctgagcttcgtgacgcggaagcgtatccggaggactgtgcgccgggcc
ctgggccgcgtgaccgcctgccaggctgacaggcactcgctcatggccaagtacatcatg
gacctggagaggctggacccggccagggccgccgagaccttcctcgtgagcctccccggg
gctgccggtggccaggatgctccggggctgctccgagtggctggtgacagcggcatccac
tggagtccgggaggacacgaggccctccagcccttctgcgactttccagaaattgtggac
atcagcatcaagcaggcgcctcgtgttggccccgccggggagcaccgcctggtcaccgtc
accaggacggacaaccagatcctggaggccgagttcccggggctgcccgctgccctgtcc
ttcgtggcgctcgtggacggctacttccggctgacttccgactccaggcacttcttctgc
aaggaggttgcgccgccgcggctgctggaggaggtggccgagcagtgccacggtcccatc
accctggattttgccatcaacaagctcaagacccggggctcccttcccggctcctatgtt
ctccgccgcagcccccaggatttcgacagcttcctcctcactgtctgcgtccagaccccc
ctgggtcctgattacaagggctgcctcatccggtgtgaccccacgggaaccttctccctg
gctggcctcggccggccccacagcagtcttcgagagctcttggcagcctgctgggatgct
gggctgcacgtggatggggttgcgctgaacctcacctcctgctgcgcccccagacccaaa
gaaaagtccaacctgatcgtggtacggagaggttgcagcgctcccacgtcatcccttgtt
tggccccaatcccagtgccagctgagtcagatgacgtttcacaagatccctgctgacagc
ctggagtggcatgagaacctgggtcatgggtccttcaccaagatttaccgaggttgtcgc
catgaggctgtggacggggaagcccgggagacagaggtgctactcaaagtgatggatgcc
aagcacagaaactgcatggagtccttcctggaagcagcgagcctgatgagccaagtgtcg
tatcagcacctcgtgttgctccacggcgtgtgcatggctggagacagtgtcatggtgcag
gaattcgtgcgcctgggagccctggatacatatctgcgcaagtctggccccctggtacca
gccagctggaagctgcaggtgatcaaacagctggcctatgccctcaactatctggaagac
aaaggcctcccccatggcaatgtctcagcccggaaggtgctcttggctcgggagggggct
gacgggaacctgcccttcatcaagttgagtgaccctggtgtcagccccactgtgctgagc
ctggagatgctcactgacaggatcccctgggtggcccctgagtgtctccaggaggcccgg
acccttggcttggaagctgacaagtggggtttcggtgccacagtctgggaagtgttcagc
gggatcccgatgcccatcagtaccctggatcctgccaagaagctccagttttacgaggaa
cggcagcaccttcctgcccccaagtggatggagctggccacactgatccaacagtgcatg
gcctatgagccaggccagaggccctccttccgcgccatcatccgtgacctgaacagcctc
atcacttcagattatgagctcctctcagaccccacacctggtgccttggcgccccgtgat
gggctgtggaatggcgcccagctctacgcctgccaggaccctaccatttttgaggagagg
catctcaagtacatctcacagctgggcaagggcaactttggcagcgtggagctgtgccgc
tatgacccgctgggcgacaacacgggcgccctagtggctgtgaagcagcttcagcacagc
gggcccgaccagcagagggacttccagcgggagatccagatcctcaaagccctccacagc
gacttcattgtcaagtaccgcggtgtcagctatggcccgggccgccagagcctgcggctg
gtgatggagtacctgcccagcggctgcctgcgcgacttcctgcagcgacaccgcgcgcgc
ctcgacgccagccgcctgctcctctacgcctcgcagatctgcaagggcatggagtacctg
ggctcccgccgctgcgtgcaccgcgacctggcggcccgtaacatcctggtggagagcgag
acgcacgtcaagatcgccgactttggcctcgccaagctgctgccgctcgacaaagactac
tacgtggtccgcgagcccggccagagccccatcttctggtatgccccagagtccctctct
gacaacatcttctcgcgccagtcggacgtctggagcttcggggtcgtcctgtacgagctt
ttcacctacggcagcaagaattgcagcccctcagccgagttcctccgtatgatgggatgt
gagcgagacgtccccgccctctgccgcctcctggagctgctggctgagggccagaggctg
cccgcgcctcccgcctgccccggtgaggttcatgagctcatgaagctgtgctgggccccg
agcccgcaagaccggccaacattcagtgccctgggcccccagctggatacactgtggagt
ggaagccggggggtagcatagagcgaagttgccactctctgggcttcccgcttcacagag
atccccacggggcaatga
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