Panthera pardus (leopard): 109258507
Help
Entry
109258507 CDS
T06062
Symbol
BRCA1
Name
(RefSeq) breast cancer type 1 susceptibility protein isoform X1
KO
K10605
breast cancer type 1 susceptibility protein [EC:
2.3.2.27
]
Organism
ppad
Panthera pardus (leopard)
Pathway
ppad01524
Platinum drug resistance
ppad03440
Homologous recombination
ppad03460
Fanconi anemia pathway
ppad04120
Ubiquitin mediated proteolysis
ppad04151
PI3K-Akt signaling pathway
ppad05206
MicroRNAs in cancer
ppad05224
Breast cancer
Brite
KEGG Orthology (KO) [BR:
ppad00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
109258507 (BRCA1)
09124 Replication and repair
03440 Homologous recombination
109258507 (BRCA1)
03460 Fanconi anemia pathway
109258507 (BRCA1)
09130 Environmental Information Processing
09132 Signal transduction
04151 PI3K-Akt signaling pathway
109258507 (BRCA1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
109258507 (BRCA1)
09162 Cancer: specific types
05224 Breast cancer
109258507 (BRCA1)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
109258507 (BRCA1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
ppad01009
]
109258507 (BRCA1)
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
ppad04121
]
109258507 (BRCA1)
03036 Chromosome and associated proteins [BR:
ppad03036
]
109258507 (BRCA1)
03400 DNA repair and recombination proteins [BR:
ppad03400
]
109258507 (BRCA1)
Enzymes [BR:
ppad01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.27 RING-type E3 ubiquitin transferase
109258507 (BRCA1)
Protein phosphatases and associated proteins [BR:
ppad01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
109258507 (BRCA1)
Ubiquitin system [BR:
ppad04121
]
Ubiquitin ligases (E3)
Single Ring-finger type E3
Other single Ring-finger type E3
109258507 (BRCA1)
Multi subunit type E3
BRCC complex
109258507 (BRCA1)
Chromosome and associated proteins [BR:
ppad03036
]
Eukaryotic type
Centrosome formation proteins
Centrosome duplication proteins
Regulators of centriole replication
109258507 (BRCA1)
DNA repair and recombination proteins [BR:
ppad03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
BRCA1-core complex
109258507 (BRCA1)
BRCA1-A complex
109258507 (BRCA1)
BRCA1-B complex
109258507 (BRCA1)
BRCA1-C complex
109258507 (BRCA1)
BRCA complex
109258507 (BRCA1)
FA (Fanconi anemia) pathway
Downstream FA components
109258507 (BRCA1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
BRCT_assoc
BRCT
zf-C3HC4
zf-C3HC4_2
zf-RING_UBOX
zf-C3HC4_4
zf-C3HC4_3
zf-RING_2
zf-RING_5
RING_XB3-XBAT31
BRCT_2
zf-Nse
zf-RING_6
zf-ANAPC11
zf-RING_10
zf-rbx1
RTT107_BRCT_5
Prok-RING_4
Motif
Other DBs
NCBI-GeneID:
109258507
NCBI-ProteinID:
XP_019290872
Ensembl:
ENSPPRG00000023630
UniProt:
A0A9V1EX31
LinkDB
All DBs
Position
Unknown
AA seq
1874 aa
AA seq
DB search
MDLSADRVEEVQSVLNAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQRKGPSQ
CPLCKNDITKRSLQESTRFSQLVEELLNIIHAFELDTGLQFANSYNFSKKENNSPEHLKE
EVSIIQSMGYRNRAKRLRQSEPENPSLQETSLSVQLSNFGIVRSLRTKQQIQPQNKSVYI
ELGSDSSEDTVNKASYFSVGDEELLGITPQGARAEASLNPAKKASCEFSEEITNIEHRQP
SNKDLTTTEKHATEKHPEKYQGISVSNLHVEPCATNTHASSLQHENSSLLLTKDRMNVEK
AEFCNESKQPGVARSQQSRWAESKETRNDRQTPNTEKKVVLNADPLCRRKLSKQKSPCSD
SPRDSQDVPWITLNSSIQKVNEWFSRSDEMLTSDDSHDGGSESNPGVAGAVEVPNEVDGY
SGSSEKIDLMASDPHDALICESERVHTKPVESNIEDKIFGKTYRRKASLPNLSHTSEDLI
IGACAIEPQITQAHPLTNKTKRKRRSTAGLHPEDFIKKVDLAIVQKTPEKLIEGTDRIGQ
NGHVMNITNNDPENGTKGDYVQKEKNAKPTESLEKESAFRTKAEPISSSISNMESELNSH
SSRAPKENRLRRKSSTRHMRALELVVNRNPSPPDHTELQIDSCSSSEEMVKRKSSEQMLV
RHSKTLQLVENKEPAPGAKKRNKPNEQINKRLASNTFPELNLTNIPGVFTNCSSSNTLQE
FVNPGIQREELEESRGTIHVSDRTRDPKELVSSGGRSLQTERSIESTSISLVPDTDYGTQ
DSISLLEADTLGKAKTAPNQHVSLCAVIENPKEATHGCSKDTRNGTEGFTDPLRREDNHT
QETSIEMEENELDTQYLYNTFKVSKRQSFALFSNPGNPEKECATVWARSTSLRKQSPKVA
LEYEQKEENQGKKQSEIKHVQAVRATAGFSAVSQKVEKPGDYAKCSIKGVPGLCQSSQFR
GNETELFIANNHDISKNPYHIPPLSPIRSSVNAVCKKNLSEEKFEQRSMSPERAVGNESV
IQSTVSTISQNNIRENTFKEVSSSSVNEVGSSANEVGSSINEVGSSGENIQTELGRNRGP
KLSAMLRLGLMQPEVYEQSLPISNCKCPEMKRQGENEGVVQSVNADFSPCLISDNVEQPM
ESSRASQVCSETPNDLLNGAEIKGKISFAESAKERSAVFGKSVQKGEFRRSPSPLDHTHL
AQGHQTETRKLQSSEENVSSEEEELPCFQHLLFGKATSIPSQSTSHNAIATEGLSKKTGA
NLESLKDSLHDCSNQVTSAKESQEHHLSEEARCSGSLFSSQCSASEDSAVNTNTQDPFLM
FDPPSKQVRHQSKNVDVLSDEELVSYDDEREPGLEEDNHEEEQSVDSNLGEAASGYESET
SLSEDCSGVSSQSDILTTQQRDTMQDNLIKLQQEMAELEAVLEQHESQPSNSSPALITDS
YAPEDLFNPEQNTSEKAVLTSEKSSDCLISQNPESLSADKFQVSLDSSTSKTKEPGMRRS
SPSQSRLLDTKQCVHSHSSSLQSTNCLSQKELIKVVDGEELQLTKSEPRDFMEQSYMPRQ
DLEGTPYFESGISLFSDDPESDLSVDRAPEPVHVSSMPTSTSALKLPQFQVEESAKSTAA
VHITNTAGYNKREDIEGKEKPETMSSTKRVNKRISMVASGLTPKELVLVQKFARRHQITL
TNVISEETTHVIMKTDAEFVCERTLKYFLGIAGGKWVVSYFWVTQSIKERKMLDEHDFEV
RGDVVNGRNHQGPKRARESRDRKIFGGLEICCYGPFTNMPTDQLEWMVRLCGASVVKRPS
LFTLSKATHPVVVVQPDAWTEDSGFHAIGQMCEAPVVTREWVLDSVALYQCQELDTYLIP
QIPRATADLSQPCV
NT seq
5625 nt
NT seq
+upstream
nt +downstream
nt
atggatttatctgcagatcgtgttgaagaagtacaaagtgtccttaatgctatgcagaaa
atcttagagtgtccaatctgtctggagttgatcaaagagcctgtttccacaaagtgtgat
cacatattttgcaaattttgtatgctgaaacttctcaaccagaggaaagggccttcacag
tgtcctttgtgtaagaatgatataaccaaaagaagcctacaggaaagtacaagatttagt
caacttgttgaagagctgttgaacatcattcatgcttttgagcttgacacaggattgcag
tttgcaaacagctataacttttcaaaaaaggaaaataactctcctgagcatctgaaggag
gaggtttctattatccaaagtatgggctatcgaaaccgtgctaaaagacttcgacagagt
gaacctgaaaaccctagcttgcaggaaaccagtcttagtgtccaactctctaactttgga
attgtgagatctctgaggacaaagcagcagatacaaccacagaataagtctgtctacatt
gaattgggatctgattcttctgaagatacagtgaataaggcaagttatttcagtgtggga
gatgaagaattgttaggaatcacccctcaaggagccagagctgaagccagtttgaatcct
gcaaaaaaggcctcttgtgaattttctgaggagataacaaatattgaacatcgtcaaccc
agtaataaagatttgaccaccactgagaagcatgcaactgaaaagcatccagaaaagtat
cagggtatttctgtttcaaacttgcatgtggagccatgtgccacaaatactcatgccagc
tcattacagcatgagaacagcagtttattactcactaaagacagaatgaatgtagaaaag
gctgaattctgtaatgaaagcaaacagcctggcgtagcaaggagccaacagagcagatgg
gctgaaagtaaggaaacacgtaatgataggcagactcccaacacagagaaaaaagtagtt
ctgaatgctgatcccctgtgtaggagaaaactgagtaagcagaaatctccatgctctgac
agtcctagagattcccaagatgtaccttggataacactgaatagtagcatacagaaagtt
aacgagtggttttccagaagtgatgaaatgttaacttctgatgactcacatgatggggga
tctgaatcgaatcctggagtagctggtgcagtagaagttccaaatgaagtggatggatat
tctggttcttctgagaaaatagacttaatggccagtgatcctcatgatgctttgatatgt
gaaagtgaaagagtccacaccaaaccagtagagagtaatattgaagataaaatatttggg
aaaacctatcggaggaaggcaagccttcctaatttgagccacacaagtgaagatctcatt
ataggagcatgtgctatagaacctcagataacacaagcccatcccctcacaaataaaaca
aagcgtaaaaggagatctacagcaggccttcatcctgaggattttatcaagaaagtagat
ttggccattgttcaaaagactcctgaaaagctaattgagggaactgatcgaatagggcaa
aatggtcatgtgatgaatataacaaataatgatcctgagaatgggacaaaaggtgattat
gttcagaaagagaaaaatgctaagccaacagaatcattggaaaaagaatctgcttttaga
accaaagctgaaccaataagcagcagtataagtaatatggaatcagaattaaatagccac
agttcaagggcacctaaggagaacaggctgaggaggaagtcctctaccaggcacatgcgt
gcgctggaattagtagtcaatagaaatccaagcccacctgatcataccgaactacagatt
gatagctgttctagcagtgaagagatggtgaaaagaaaaagttcggaacaaatgctagtc
agacacagcaaaacacttcaactcgtggaaaataaagaacctgcacctggagccaagaag
cgtaacaagccaaatgaacaaataaataaaagacttgccagtaacacttttccagagcta
aatttaacaaacatacctggggtttttactaactgttcaagttctaatacacttcaagag
tttgtcaaccctggcattcaaagagaagaactagaagagagccgaggaacgattcacgtg
tctgataggaccagagatcccaaagagctggtatcgagtggaggaagaagtttgcaaact
gaaagatctatagagagtaccagtatttcattggtacctgataccgattatggcactcag
gatagtatctcattactggaagctgacaccctagggaaggcaaaaacagcaccaaatcaa
catgtgagtctgtgtgcagtaattgaaaaccccaaggaagctacccatggttgttccaaa
gatactagaaatggcacagagggttttacagatcctctgagacgtgaagataaccatact
caggagacaagtatagaaatggaagagaatgaacttgatacgcagtatttatacaatacg
ttcaaggtttcaaaacgtcagtcatttgctctgttttcaaatccaggaaatccagaaaag
gaatgtgctacagtctgggcccgttccacgtccttaaggaaacaaagtccaaaagttgct
cttgaatatgaacaaaaagaagaaaatcagggaaagaaacagtctgaaatcaagcacgtg
caggcagtccgtgcaactgcaggcttttctgcagtcagtcagaaagtggagaagccaggt
gattatgccaaatgtagcataaaaggagtccctgggctctgtcagtcatctcagttcaga
ggcaatgaaactgaactctttattgcaaataaccatgacatttcaaaaaatccttatcat
ataccaccactttctcccatcagatcatctgttaatgctgtatgtaagaaaaacctgtca
gaggaaaagtttgagcagcgttcaatgtcacctgaaagagcagtgggaaatgagagcgtc
attcaaagtacagtgagcacaattagccaaaataacattagagaaaacacttttaaagaa
gttagctcaagcagtgttaatgaagtaggttccagtgctaatgaagtaggctctagcatt
aatgaagtaggttccagtggtgaaaacattcaaacagaactgggtagaaaccgaggacct
aagttaagtgctatgctcaggttaggtcttatgcaacctgaagtctatgagcaaagtctt
cctataagtaattgtaaatgtccagaaatgaaaaggcaaggagaaaatgaaggagtagtt
cagtctgttaatgcagatttttctccatgtctaatttccgataatgtagaacaacctatg
gaaagtagccgtgcttctcaggtttgttctgagacacccaatgatctattaaatggtgct
gaaataaagggaaaaatcagctttgctgaaagtgctaaggaaagatctgctgtttttggc
aagagtgtccagaaaggagaattcagaaggagccctagccctttagaccatacacatctg
gctcagggtcaccaaacagagaccaggaagttacagtcctcagaagagaacgtgtctagt
gaggaggaagagcttccctgcttccaacacttactatttggtaaagcaaccagtatacct
tctcagtctaccagccataatgccattgccacggagggtctgtctaagaaaacaggggcg
aacctagaatcattgaaggatagcttacatgactgcagtaaccaggtaacatcagcaaag
gagtcccaggaacatcaccttagtgaggaagcgaggtgttccggtagcttattttcttca
cagtgcagtgcatcggaagactcggctgttaatacaaatacccaggatcctttcttgatg
tttgatcctccttccaaacaagtgaggcatcagtccaaaaatgtggacgttctgagtgat
gaggaattggtttcatatgatgatgaaagggaacctggcctggaagaggataatcacgaa
gaagagcagagtgtggattcaaacttaggtgaagcggcatctgggtatgagagtgaaaca
agcctctctgaagactgttcaggggtgtcctctcagagtgatattttaaccactcagcag
agggataccatgcaagacaacctgatcaagctccagcaggaaatggccgaactggaagcc
gtgttagagcagcacgagagccagccttctaacagctcccctgccctcataacagattct
tatgcccctgaggacctgttcaatccggaacaaaacacatcagagaaagcagtattaact
tcagagaaaagtagtgactgccttataagccagaatcccgaaagcctctctgctgacaaa
tttcaagtatctctggatagttccaccagtaaaactaaagaaccgggaatgagaaggtct
tctccttctcaatcacggctgttagatactaagcagtgtgtgcacagccactcaagcagt
cttcagagcacaaactgcctgtctcagaaggagctaattaaggttgtcgatggggaggag
ctacaactgactaagtcagagccccgagatttcatggagcagtcttatatgccaagacaa
gatctggagggaaccccttacttcgaatctggaatcagcctcttctctgatgaccctgag
tctgatctctctgtggacagagccccagaaccggttcatgttagcagcatgccaacttca
acctctgccttgaaattaccccaatttcaagttgaagaatcagccaagagtacagctgct
gttcatattactaatactgctgggtataataagagggaagacattgagggcaaggagaag
ccagaaacgatgtcttcaacaaaaagagtcaacaaaagaatatctatggtggcatcaggc
ttgactccaaaagaattggtgcttgtgcagaagtttgccagaagacaccaaatcacctta
actaatgtaatttctgaagagactactcatgtcattatgaaaacagatgctgagtttgtg
tgtgaacggacactgaaatattttctgggtattgcaggaggaaaatgggtagttagctat
ttctgggtgacccagtccattaaagaaagaaagatgctagatgagcatgattttgaagtc
agaggagatgttgtcaatggaagaaaccaccagggtccgaagcgagcaagagaatcccgg
gacagaaagatcttcgggggcctagaaatctgttgctatgggccctttaccaacatgccc
acagatcaactagagtggatggtgcgcctctgtggggcttctgtggtgaagaggccttcg
ttattcactctcagcaaggctactcacccagttgtggtcgtgcaaccggatgcctggaca
gaggacagtggcttccatgcgattgggcagatgtgtgaggcacctgtggtgacccgagag
tgggtattggacagtgtagccctctaccagtgccaggagctggacacctacctgatcccc
cagattcccagagctactgctgacctcagccagccatgtgtgtag
DBGET
integrated database retrieval system
