KEGG   Panthera pardus (leopard): 109262509
Entry
109262509         CDS       T06062                                 
Symbol
TLR2
Name
(RefSeq) toll-like receptor 2
  KO
K10159  toll-like receptor 2
Organism
ppad  Panthera pardus (leopard)
Pathway
ppad04145  Phagosome
ppad04151  PI3K-Akt signaling pathway
ppad04613  Neutrophil extracellular trap formation
ppad04620  Toll-like receptor signaling pathway
ppad05132  Salmonella infection
ppad05134  Legionellosis
ppad05140  Leishmaniasis
ppad05142  Chagas disease
ppad05144  Malaria
ppad05145  Toxoplasmosis
ppad05146  Amoebiasis
ppad05152  Tuberculosis
ppad05161  Hepatitis B
ppad05162  Measles
ppad05168  Herpes simplex virus 1 infection
ppad05169  Epstein-Barr virus infection
ppad05170  Human immunodeficiency virus 1 infection
ppad05171  Coronavirus disease - COVID-19
ppad05205  Proteoglycans in cancer
ppad05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
ppad05321  Inflammatory bowel disease
ppad05323  Rheumatoid arthritis
ppad05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ppad00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    109262509 (TLR2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    109262509 (TLR2)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    109262509 (TLR2)
   04620 Toll-like receptor signaling pathway
    109262509 (TLR2)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    109262509 (TLR2)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    109262509 (TLR2)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    109262509 (TLR2)
   05161 Hepatitis B
    109262509 (TLR2)
   05171 Coronavirus disease - COVID-19
    109262509 (TLR2)
   05162 Measles
    109262509 (TLR2)
   05168 Herpes simplex virus 1 infection
    109262509 (TLR2)
   05169 Epstein-Barr virus infection
    109262509 (TLR2)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    109262509 (TLR2)
   05134 Legionellosis
    109262509 (TLR2)
   05152 Tuberculosis
    109262509 (TLR2)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    109262509 (TLR2)
   05144 Malaria
    109262509 (TLR2)
   05145 Toxoplasmosis
    109262509 (TLR2)
   05140 Leishmaniasis
    109262509 (TLR2)
   05142 Chagas disease
    109262509 (TLR2)
  09163 Immune disease
   05323 Rheumatoid arthritis
    109262509 (TLR2)
   05321 Inflammatory bowel disease
    109262509 (TLR2)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    109262509 (TLR2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:ppad04131]
    109262509 (TLR2)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:ppad04147]
    109262509 (TLR2)
   04054 Pattern recognition receptors [BR:ppad04054]
    109262509 (TLR2)
   04090 CD molecules [BR:ppad04090]
    109262509 (TLR2)
   00536 Glycosaminoglycan binding proteins [BR:ppad00536]
    109262509 (TLR2)
Membrane trafficking [BR:ppad04131]
 Endocytosis
  Phagocytosis
   Toll-like receptors
    109262509 (TLR2)
Exosome [BR:ppad04147]
 Exosomal proteins
  Exosomal proteins of breast milk
   109262509 (TLR2)
Pattern recognition receptors [BR:ppad04054]
 Membrane-bound pattern recognition receptors
  Toll-like receptors
   109262509 (TLR2)
CD molecules [BR:ppad04090]
 Proteins
  109262509 (TLR2)
Glycosaminoglycan binding proteins [BR:ppad00536]
 Hyaluronan
  Cell surface receptors
   109262509 (TLR2)
SSDB
Motif
Pfam: LRR_8 LRR_4 TIR TIR_2 LRR_1 LRR_5 LRR_9 LRR_6 LRR_LRWD1 LRRCT
Other DBs
NCBI-GeneID: 109262509
NCBI-ProteinID: XP_019296772
Ensembl: ENSPPRG00000018231
UniProt: A0A9W2VEW0
LinkDB
Position
Unknown
AA seq 784 aa
MSRVLWTVWVLGAVTSLSKEVAPHQTSLSCDSTGVCEGHSRSLNSIPSGLTATVRSLDLS
NNEITYIGNSDLQGCVNLRALRLESNEINTIEEDSFFSLRSLEHLDLSYNHISNLSSSWF
RPLSSLKFLNLLGNPYKSLGQTPLFSQLTTLRILKVGNTYSFTAIQEKDFAGLTFLEELE
IDASNLQKYEPESLKSIQNISHLALRMKQPDLLLEIFVDLLSSVEHLELRDTHLNTLHFS
KASINETNTSIKKWTFRNVKITDGSFSELVKLLNYVSGVLEVEFEDCTLHGLGDFDVSDM
GKIGSVGGIETLTVRRLVIPYFYSFYDLSSVYSLTERVKRITVESSKVFLVPCLLSQHLK
SLEYLDLSDNLMVEEYLRNAACEHAWPLLQTLILRQNRLKSLEKTGETLLTLKNLINLDI
SKNSYLSMPETCQWPEKLKYLNLSNTRIYSLTRCIPWTLEILDISNNNLNSFSLTLPQLK
ELYISRNKLKTLPDASFLPMLQVMRISRNAINTFSKEQLDSFQRLTTLEAGGNNFICSCE
FLSFTREQQALAQTLTDWPHNYLCDSPFYVRGQRVQDTHLPASECHRAALVSAVCCVLFL
LILLTGVLCHRFHGLWYLKMMWAWLQAKRKPRKAPQRDLCYDAFVSYSERDSHWVENLMV
QELEHFDPPFKLCLHKRDFIPGKWIIDNIIDSIEKSHKTIFVLSENFVKSEWCKYELDFS
HFRLFDENNDAVILILLEPIEKKAIPQRFCKLRKIMNTKTYLEWPTDEAQQEGFWLNLRT
AIKS
NT seq 2355 nt   +upstreamnt  +downstreamnt
atgtcacgtgttttgtggacagtatgggtcttgggggctgtaaccagcctctccaaggaa
gtggcccctcatcagacttctctgtcctgtgactccacgggcgtctgcgagggccactcc
agatctttaaactccatcccctcaggactcacggcaactgttagaagccttgacctctcc
aacaacgagatcacctacattggcaacagtgacctgcagggctgtgtgaacctcagggct
ctgaggctggagtctaatgaaattaacacgatagaggaagattcttttttttccctgagg
agtctcgaacatttggacttatcctataatcacatatctaatttatcatcctcgtggttc
aggcccctttcttccttgaagttcttaaacttgctgggaaatccttacaaatcacttggg
caaacacctcttttttctcagctcacaactttgcgaattctgaaagtaggaaatacttac
agtttcactgcgattcaggaaaaggattttgctgggctgacttttcttgaggaacttgag
attgatgcttcaaatctccagaagtatgagccagagagtttgaagtccattcagaacatc
agccatctggcccttcgtatgaaacagcctgatttgctgctggagatttttgtagatctt
ttaagttctgtggaacatttggaactgagagatactcatttgaacactttacatttttca
aaagcatccatcaatgaaacaaatacgtcgattaaaaagtggacgtttagaaacgtgaaa
atcactgatggaagttttagcgaacttgtaaaactgttgaattatgtttctggagtgtta
gaagtagagtttgaggactgtactctccatgggcttggcgactttgacgtatctgacatg
ggcaaaattggaagtgtaggtgggatagagacattaacagtacggaggttggtcattcca
tacttctactcgttttatgatctgagtagtgtgtattcactgacagaaagagttaaaaga
atcacagtagaaagcagtaaggtgtttctggttccttgtttactttcacaacatttaaaa
tcattagaatatttggatctcagtgacaatttaatggttgaagaatacttgagaaatgca
gcctgtgagcatgcctggcccctcctacaaaccttaattttaaggcaaaatcgtttgaaa
tcattagaaaaaaccggagaaactttgcttactctgaaaaacttgattaacctggatatt
agtaagaacagttatctttctatgcctgaaacttgtcagtggccagaaaagttgaaatat
ttgaacttatccaacaccagaatatacagcttaacccgatgcatcccctggacactggaa
attttagatattagcaataacaatctcaattcattttctctgactttgccacaactcaaa
gaactttatatttccagaaataagttgaagactctaccagatgcctccttcttacccatg
ttacaggtcatgagaatcagcagaaatgcaataaacactttctctaaggagcaacttgat
tcttttcaaagactgacgactttggaagctggcggcaacaatttcatttgctcctgtgaa
ttcctgtctttcacgcgggagcagcaagcactggcccagaccctgaccgactggccacac
aattacctgtgtgactctccattctatgtgcggggccagcgggttcaggacacccatctc
ccagcttctgaatgccacagggcagctctggtgtctgccgtgtgctgtgtccttttcttg
ttgatcctgctcacgggggttctgtgccaccgtttccacgggctgtggtacctgaaaatg
atgtgggcttggctccaggccaaaaggaagcccaggaaagctccccagcgggacctctgc
tatgacgcctttgtgtcttacagcgagcgggattcccactgggtggagaaccttatggtc
caggagctggagcacttcgaccctcccttcaagttgtgtcttcacaagcgggacttcatt
cccggcaaatggattatcgacaacatcatcgactccatcgagaagagccacaagaccatc
tttgtgctttctgaaaactttgtcaagagtgagtggtgcaagtacgagctggacttctcc
cacttccgtctgtttgatgagaacaacgatgctgtcattctcattcttctggagcccatt
gagaaaaaggccatcccccagcgtttctgtaagctgcggaagataatgaacaccaagacc
tacctggagtggcccacagacgaagctcagcaggaagggttttggttaaacttgagaact
gcaataaagtcctag

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