Panthera pardus (leopard): 109263394 Help Entry 109263394         CDS       T06062                                  Symbol HK2 Name (RefSeq) hexokinase-2 isoform X1   KO K00844   hexokinase [EC:2.7.1.1] Organism ppad  Panthera pardus (leopard) Pathway ppad00010   Glycolysis / Gluconeogenesis ppad00051   Fructose and mannose metabolism ppad00052   Galactose metabolism ppad00500   Starch and sucrose metabolism ppad00520   Amino sugar and nucleotide sugar metabolism ppad00524   Neomycin, kanamycin and gentamicin biosynthesis ppad01100   Metabolic pathways ppad01200   Carbon metabolism ppad01250   Biosynthesis of nucleotide sugars ppad04066   HIF-1 signaling pathway ppad04910   Insulin signaling pathway ppad04930   Type II diabetes mellitus ppad04973   Carbohydrate digestion and absorption ppad05230   Central carbon metabolism in cancer Module ppad_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate ppad_M00549   UDP-Glc biosynthesis, Glc => UDP-Glc ppad_M01015   GDP-Man biosynthesis, Man => GDP-Man Brite KEGG Orthology (KO) [BR:ppad00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     109263394 (HK2)    00051 Fructose and mannose metabolism     109263394 (HK2)    00052 Galactose metabolism     109263394 (HK2)    00500 Starch and sucrose metabolism     109263394 (HK2)   09107 Glycan biosynthesis and metabolism    00520 Amino sugar and nucleotide sugar metabolism     109263394 (HK2)   09110 Biosynthesis of other secondary metabolites    00524 Neomycin, kanamycin and gentamicin biosynthesis     109263394 (HK2)  09130 Environmental Information Processing   09132 Signal transduction    04066 HIF-1 signaling pathway     109263394 (HK2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     109263394 (HK2)   09154 Digestive system    04973 Carbohydrate digestion and absorption     109263394 (HK2)  09160 Human Diseases   09161 Cancer: overview    05230 Central carbon metabolism in cancer     109263394 (HK2)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     109263394 (HK2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:ppad04131]     109263394 (HK2) Enzymes [BR:ppad01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.1  hexokinase      109263394 (HK2) Membrane trafficking [BR:ppad04131]  Autophagy   Mitophagy    Other mitophagy associated  proteins     109263394 (HK2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Hexokinase_2 Hexokinase_1 Motif Other DBs NCBI-GeneID:  109263394 NCBI-ProteinID:  XP_019298379 Ensembl:  ENSPPRG00000007681 UniProt:  A0A9V1F9M0 LinkDB All DBs Position Unknown AA seq 917 aa AA seqDB search MIASHLLAYFFTELNHDQVQKVDQYLYHMRLSDENLLEISQRFRKEMEKGLGATTHPTAS VKMLPTFVRSTPDGTEHGEFLALDLGGTNFRVLRVRVTDNGLQKVEMENQIYAIPEDLMR GSGTQLFDHIAECLANFMDKLQIKDKKLPLGFTFSFPCVQTKLDESFLVSWTKGFKSSGV EGKDVVTLIRKAIQRRGDFDIDIVAVVNDTVGTMMTCGYDDQNCEIGLIVGTGSNACYME EMRHIDMVEGDEGRMCINMEWGAFGDDGILDDFRTEFDQEIDMGSLNPGKQLFEKMISGM YMGELVRLILVKMAKEELLFGGKLSPGLLATGHFETKDVSDIEGEKDGIRKAREVLVRLG IDPTQEDCVATHRVCQIVSTRSASLCAATLAAVLRRIKENKGEERLRSTIGVDGSVYKKH PHFAKRLHKTVRRLVPDCDVRFLRSEDGSGKGAAMVTAVAYRLADQHRARQNTLESLKLN REQLLEVKKRMKVEMERGLSKETHAIAPVKMLPTYVCATPDGTEKGDFLALDLGGTNFRV LLVRVRNGKRRGVEMHNKIYSIPQEVMHGTGDELFDHIVQCIADFLEYMGMKGVSLPLGF TFSFPCQQNSLDESILLKWTKGFKASGCEGEDVVTLLKEAIHRREEFDLDVVAVVNDTVG TMMTCGYEDPHCEIGLIVGTGSNACYMEEMRNVELVEGEEGRMCVNMEWGAFGDNGCLDD FRTEFDVAVDELSLNPGKQRFEKMISGMYLGEIVRNILIDFTKRGLLFRGRISERLKTRG IFETKFLSQIESDCLALLQVRAILHHLGLESTCDDSIIVKEVCTVVARRAAQLCGAGMAA VVDKIRENRGLDTLKVTVGVDGTLYKLHPHFAKVMHETVKDLAPKCDVSFLESEDGSGKG AALITAVACRIREAGQR NT seq 2754 nt NT seq  +upstreamnt  +downstreamnt atgatcgcctcacatctgctcgcctacttcttcacggagctcaaccatgaccaagtgcag aaggtggaccagtatctctaccacatgcgtctttctgatgagaaccttctggagatctct cagcggttccgcaaggagatggagaaagggcttggagccaccacccaccccactgcttca gtgaaaatgctgcccacctttgtgaggtctactccagatgggacagaacatggagagttt ctggctctggaccttggggggaccaacttccgtgtgcttcgtgtaagagtaacagacaat gggctccagaaggtcgagatggagaaccagatctatgccatccctgaggacctcatgcga ggcagcggcacccagctgtttgaccacattgctgaatgcctggctaacttcatggacaag ctacaaatcaaagacaagaagctccccttgggttttactttctcattcccctgtgtccaa acgaagctagatgagagtttcctagtctcctggaccaaggggttcaagtccagtggcgtg gaaggcaaagacgtggttactctgatccggaaggccatccagaggagaggggactttgat attgatattgtggccgtggtgaatgacacagttgggaccatgatgacctgtggttatgat gaccagaattgtgagattggtctcattgtgggcacgggcagcaacgcctgctacatggaa gagatgcgccacattgacatggtggagggcgacgaggggcggatgtgtatcaacatggag tggggggcctttggggacgacggcatacttgatgacttccgcactgagtttgatcaggag atcgacatgggctccctgaaccctgggaagcaactatttgagaagatgatcagtgggatg tatatgggtgaactggtgagacttatcctggtgaagatggccaaggaggagctgcttttt ggggggaagctcagcccagggctcctcgccactggccactttgagaccaaagacgtttca gatattgaaggggagaaggacggcatccggaaggcccgtgaggtgctagtgcggctgggc atagacccgacgcaggaggactgtgtggccactcaccgggtgtgccagatcgtgtccaca cgctcagccagcctgtgtgcagccaccctggcagccgtgctgcggcgcatcaaggagaac aagggcgaggagaggctgcgctccaccattggggttgatggttctgtctacaagaagcac cctcatttcgccaagcgtcttcacaagacggttcggcgcctggtgcccgactgcgacgtc cgtttcctgcgttccgaggatggcagtggcaagggggcagccatggtgacggcagtggcc taccggctggctgaccaacacagagcccgccagaataccctggagtctctgaagctgaac cgtgagcagctgctggaggttaagaagaggatgaaggtagaaatggagcgaggtctgagc aaggagacccacgccattgcccccgtcaagatgctgcccacctacgtgtgtgccacccct gatggcacagagaaaggtgacttcctggccttggaccttgggggtaccaatttccgggtc ctgctggtgcgtgtgaggaatgggaagaggcgcggagtggagatgcacaacaagatctac tctatcccacaggaggtcatgcatggcacaggggatgagctctttgaccacatcgtccag tgcatcgccgacttccttgagtacatgggcatgaagggcgtgtccctgcctctgggtttc accttctccttcccctgccagcagaacagcctggatgagagcatcctcctcaagtggact aaaggcttcaaggcatcgggctgcgagggagaggatgtggtcaccctgctgaaggaagcc attcaccggcgagaggagtttgacctggatgtggtcgccgtggtgaatgacacagttggg acgatgatgacctgtggctatgaagaccctcactgtgaaatcggcctcattgttggcacg ggcagcaacgcctgctacatggaggagatgcggaacgtggagctggtggaaggggaggag ggccggatgtgtgtcaacatggagtggggggccttcggggacaacgggtgcctggacgac ttccgcacggaatttgatgtggctgtggatgagctttctctcaaccctggcaaacagagg tttgagaaaatgatcagtggcatgtatttgggcgagattgtccgtaacatcctcatcgat ttcaccaagcgtgggctgctcttccgtggccgcatctcagaacgactcaagacaagagga atctttgaaactaagttcctgtctcagattgagagtgactgcctagccctgctgcaggtc cgcgccatcctgcaccacctggggctcgagagcacctgtgacgacagcatcatcgtgaaa gaggtgtgcacggtggtggcacggcgggcggcccagctctgtggtgcgggcatggccgcc gtggtggacaaaatacgagaaaaccgtgggctggacaccctcaaagtgacagtaggcgtg gatgggaccctctacaagctacatcctcactttgccaaagtcatgcatgagacggtgaaa gacctggctccgaaatgtgatgtgtccttcctggagtcagaggatggcagcgggaagggg gcagctctcatcactgctgtggcctgccgcatccgtgaggctggacagcgatag

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