Panthera pardus (leopard): 109264617
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Entry
109264617 CDS
T06062
Symbol
RET
Name
(RefSeq) proto-oncogene tyrosine-protein kinase receptor Ret
KO
K05126
proto-oncogene tyrosine-protein kinase Ret [EC:
2.7.10.1
]
Organism
ppad
Panthera pardus (leopard)
Pathway
ppad04010
MAPK signaling pathway
ppad04020
Calcium signaling pathway
ppad04151
PI3K-Akt signaling pathway
ppad05200
Pathways in cancer
ppad05216
Thyroid cancer
ppad05223
Non-small cell lung cancer
ppad05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
ppad00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
109264617 (RET)
04020 Calcium signaling pathway
109264617 (RET)
04151 PI3K-Akt signaling pathway
109264617 (RET)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
109264617 (RET)
05230 Central carbon metabolism in cancer
109264617 (RET)
09162 Cancer: specific types
05216 Thyroid cancer
109264617 (RET)
05223 Non-small cell lung cancer
109264617 (RET)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ppad01001
]
109264617 (RET)
Enzymes [BR:
ppad01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
109264617 (RET)
Protein kinases [BR:
ppad01001
]
Receptor tyrosine kinases (RTK)
RET family
109264617 (RET)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
RET_CLD1
RET_CLD4
RET_CLD3
Pkinase
RET_CRD
Cadherin
RIO1
Cadherin_FAT4_N
Pkinase_fungal
ABC1
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
109264617
NCBI-ProteinID:
XP_019300571
Ensembl:
ENSPPRG00000001685
UniProt:
A0A9V1FDH5
LinkDB
All DBs
Position
Unknown
AA seq
1117 aa
AA seq
DB search
MAKATATAGAARLRLLLLLPLLGEAPLGLYFARDAYWEKLYVDQPAGMPLLYVHALRDMP
EEVPTFRLGQHLYGIAYRARLHENDWIRIEEDTGLLYLNRSLDHSTWDKLSIRNGGFPVL
TIYLQVFLSPTSLREGECQWPGCARVYFSFVNTSFPACGSLKPQELCFPETGVSFRIREN
RPPGTFHQFRLLPVQFLCPNISVAYRLLEGENLPFHCAPDSLEVSTRWPLDRELREKYEL
VAACTVRVGARKEEVVMVPFPVTVYDEDDSAPTFLGGIDTASAVVEFKRKEGTVVAKIRV
FDADVVPASGELLKRYTNTLLSGDAWVLQTFRIEHSPNETLAQANGSFVRATVHDYRLVL
NRSLPISENRSLQLTVLVNDSDFQGPGEGTLFLHFNVSVLPVSLHLPSTYTFTVSRRARR
FAQIGKVCVENCQEFSGIHMQYRLQLSSTNCSVLGVVTSAEDTTGNLFVNDTEALQRPDC
SQLRYTVVAVDRPTRKQTQALLVVTVEGTYVAEEPGCPLSCAVSKRRPECEECGGLGSLT
GRCEWRQGDGKGITRNFSTCSPSIKTCPDGHCDAVESRNVNICPQDCLRGGSIIGGHEPG
ERWGIKAGFGICNCFPEEKKCFCEPEDSQEPLCDELCRTVIAAAVLFSFVVSMLLSTFCI
HRYHKNAHKPPIASAEMTFRRPAQAFPVSYSSSGARRPSMDSMENQVSVDAFKIPEDPKW
EFPRKNLVLGKTLGEGEFGKVVKATAFRLKGKAGYTTVAVKMLKENASPSELRDLLSEFN
LLKQVNHPHVIKLYGACSQDGPLFLIVEYAKYGSLRGFLRESRKAGPGYVGSGGSRSSSY
LDNPEERALTMGDLISFAWQISRGMRYLAEMKLVHRDLAARNVLVAEGRKMKISDFGLSR
DVYEEDSYVKRSKGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPP
ERLFNLLKTGYRMERPDNCSEEMYGLMLQCWKQEPDKRPVFADISKDLEKMMVKNRDYLD
LAASTPSDSLLYDDGLSEEETPLVDCNNAPLPRALPSTWIENKLYGMSDPNWPEESPVPL
TRADGTNTVCPRYANDSVYANWMVSPSAAQLMDAFDS
NT seq
3354 nt
NT seq
+upstream
nt +downstream
nt
atggcgaaggcgacggcgacggccggcgccgcgaggctgcggttgctgctgctgctgccg
ctgctcggcgaagctccgctgggactctacttcgccagggatgcttactgggagaaactc
tacgtggaccagccagccggcatgcccctgctctacgtccatgccctgcgggacatgccg
gaggaggtgcccaccttccgcctgggccagcacctctacggcatcgcctaccgtgcaagg
ctgcatgagaacgactggattcgcatcgaggaggacactggccttctctaccttaaccgg
agcctggatcacagcacctgggacaagctcagcatccgcaatggcggcttccctgtgctc
accatctacctccaggtcttcctgtcacctacatccctgcgtgagggcgagtgccaatgg
cccggctgtgcccgtgtgtacttctcctttgtcaacacctccttcccggcttgtggttcc
ctcaaaccccaggagctctgctttcctgagacaggtgtctccttccgcatcagagagaat
aggcctcccggcactttccaccagttccgcctgctgcctgtgcagttcctctgccccaac
atcagcgtggcctacaggctcctagaaggtgagaacctgcccttccactgcgccccggac
agcctggaggtgagcacgcgctggcccctggatcgcgagctgcgggagaagtacgagctg
gtggctgcttgcacggtgcgcgtcggcgcacgcaaggaggaggtggtgatggtgcccttc
cccgtgaccgtgtatgatgaggacgactcggcgcccaccttcctcgggggcatcgacacc
gccagcgctgtggtggagttcaagaggaaggagggcactgtggtggccaaaatacgtgtc
ttcgatgcagacgtggtgccagcatccggggagctcctgaagcgatacacaaacacacta
ctctctggggatgcctgggtcctccagacattccgtatcgagcactcccccaacgagacc
ttggcccaggccaacggcagctttgtgcgggcaactgtgcatgactacaggctggttctc
aaccggagcctccccatctcggagaaccgctccctgcagctgaccgtgctggtcaatgac
tcggacttccagggccccggggagggcaccctcttcctccacttcaacgtgtccgtgctg
cctgtcagcttgcacttgcccagcacctacaccttcactgtgagcaggcgggcccgccgc
tttgcccagattgggaaagtctgtgtggaaaactgccaggagttcagcggcatccacatg
cagtacaggctgcagctctccagcaccaactgcagtgtcctgggggtggtcacctcagca
gaggacaccacagggaaccttttcgtgaacgacacagaagccctgcagcggcccgattgc
tctcaactccggtacacggtagtggctgtcgaccggccaacccgcaagcagacccaggcc
ctgctggttgtcaccgtggaggggacatatgtggctgaggagccaggctgccccctgtcc
tgtgcagtcagcaagagacgccctgaatgtgaggagtgcggcggcctgggctctctgacg
ggcaggtgcgagtggagacagggagatggcaaaggaatcaccaggaacttctccacctgc
tcccccagcatcaagacctgccccgatggccactgtgatgccgtggagagcagaaatgtc
aacatctgcccccaggactgcctccggggcggcagcatcattggtgggcatgagccaggg
gagcgctgggggattaaagctggcttcggtatctgcaactgtttcccagaagagaagaag
tgcttctgcgaacctgaagacagccaggagccgctgtgtgacgagctctgccgcacggtg
atcgcagccgctgtgctcttctccttcgtcgtctccatgctgctctccaccttctgcatc
caccgctaccacaagaacgcccacaagccacccattgcctctgctgagatgaccttccgc
cggcctgcccaggccttcccggtcagctactcctcgtccggcgcccgccggccctctatg
gactccatggagaaccaggtctctgtggacgccttcaagatcccggaggatccaaagtgg
gaattccctcgaaagaacttggttcttgggaaaaccctgggagaaggcgaatttggaaaa
gtggttaaggcgacagccttccggctaaaaggcaaagcagggtacacaaccgtggccgtg
aagatgctgaaagagaacgcttccccaagtgagctgcgggacctgctgtcagagttcaac
ctcctgaagcaggtcaaccacccacatgtcatcaagctgtacggggcctgcagccaggac
ggcccgctcttcctcattgtggagtatgccaagtacggttccctgcggggcttcctccga
gagagccgcaaggcggggcccggctacgtgggcagcggaggcagccgcagctccagctac
ctggacaaccccgaggagcgggccctgaccatgggcgacctcatctccttcgcctggcag
atctctcgggggatgcggtacctggctgagatgaagcttgtccatcgggacttggcagcc
agaaatgtcctggtagctgaggggcggaagatgaagatttcggattttggcctgtcccga
gacgtttatgaagaggattcctatgtaaagaggagcaagggtcggattccagtcaaatgg
atggcaattgagtctcttttcgatcatatctacaccacccaaagtgatgtgtggtccttt
ggtgtcctgctgtgggagattgtgactctggggggcaacccctaccccgggatccctccg
gagcggcttttcaacctcctgaagacaggctaccggatggagaggcccgacaactgcagt
gaggagatgtacggtctcatgctgcagtgttggaagcaggaaccagacaagaggccagtg
tttgctgacatcagcaaagacctggaaaagatgatggttaagaacagagactacttggac
ctggctgcctccaccccatccgactccctgctttatgacgacggcctctcggaggaggag
acgcccctggtggactgtaataatgctcccctccctcgagccctcccctccacgtggatt
gaaaacaaactctatggcatgtcagacccgaactggcctgaagagagtcctgtaccactc
acgagagctgatggcactaacactgtgtgtccaagatatgcaaatgatagtgtatatgct
aactggatggtttcaccctcagcggcacaattaatggacgcatttgatagttaa
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integrated database retrieval system
