Panthera pardus (leopard): 109273067
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Entry
109273067 CDS
T06062
Symbol
PTK2
Name
(RefSeq) focal adhesion kinase 1 isoform X1
KO
K05725
focal adhesion kinase 1 [EC:
2.7.10.2
]
Organism
ppad
Panthera pardus (leopard)
Pathway
ppad01522
Endocrine resistance
ppad04012
ErbB signaling pathway
ppad04062
Chemokine signaling pathway
ppad04148
Efferocytosis
ppad04151
PI3K-Akt signaling pathway
ppad04360
Axon guidance
ppad04370
VEGF signaling pathway
ppad04510
Focal adhesion
ppad04670
Leukocyte transendothelial migration
ppad04810
Regulation of actin cytoskeleton
ppad04935
Growth hormone synthesis, secretion and action
ppad05100
Bacterial invasion of epithelial cells
ppad05135
Yersinia infection
ppad05146
Amoebiasis
ppad05163
Human cytomegalovirus infection
ppad05165
Human papillomavirus infection
ppad05170
Human immunodeficiency virus 1 infection
ppad05200
Pathways in cancer
ppad05202
Transcriptional misregulation in cancer
ppad05205
Proteoglycans in cancer
ppad05208
Chemical carcinogenesis - reactive oxygen species
ppad05222
Small cell lung cancer
ppad05417
Lipid and atherosclerosis
ppad05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ppad00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
109273067 (PTK2)
04370 VEGF signaling pathway
109273067 (PTK2)
04151 PI3K-Akt signaling pathway
109273067 (PTK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
109273067 (PTK2)
09144 Cellular community - eukaryotes
04510 Focal adhesion
109273067 (PTK2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
109273067 (PTK2)
09150 Organismal Systems
09151 Immune system
04670 Leukocyte transendothelial migration
109273067 (PTK2)
04062 Chemokine signaling pathway
109273067 (PTK2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
109273067 (PTK2)
09158 Development and regeneration
04360 Axon guidance
109273067 (PTK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
109273067 (PTK2)
05202 Transcriptional misregulation in cancer
109273067 (PTK2)
05205 Proteoglycans in cancer
109273067 (PTK2)
05208 Chemical carcinogenesis - reactive oxygen species
109273067 (PTK2)
09162 Cancer: specific types
05222 Small cell lung cancer
109273067 (PTK2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
109273067 (PTK2)
05163 Human cytomegalovirus infection
109273067 (PTK2)
05165 Human papillomavirus infection
109273067 (PTK2)
09171 Infectious disease: bacterial
05135 Yersinia infection
109273067 (PTK2)
05100 Bacterial invasion of epithelial cells
109273067 (PTK2)
09174 Infectious disease: parasitic
05146 Amoebiasis
109273067 (PTK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
109273067 (PTK2)
05418 Fluid shear stress and atherosclerosis
109273067 (PTK2)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
109273067 (PTK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ppad01001
]
109273067 (PTK2)
01009 Protein phosphatases and associated proteins [BR:
ppad01009
]
109273067 (PTK2)
Enzymes [BR:
ppad01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
109273067 (PTK2)
Protein kinases [BR:
ppad01001
]
Non-receptor tyrosine kinases
FAK family
109273067 (PTK2)
Protein phosphatases and associated proteins [BR:
ppad01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
109273067 (PTK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Focal_AT
Pkinase
FERM_C_FAK1
FERM_N_2
FERM_M
Kinase-like
Haspin_kinase
FERM_F2
GIT1_C
ABC1
Motif
Other DBs
NCBI-GeneID:
109273067
NCBI-ProteinID:
XP_019315277
Ensembl:
ENSPPRG00000003723
LinkDB
All DBs
Position
Unknown
AA seq
1155 aa
AA seq
DB search
MLVELAGREALRPAGAVCMEKSGCGPFPVCWAKDYDRYIAPSKIMAAAYLDPNLNHTPNS
STKTHLGTGVERSPGAMERVLKVFHYFENSSEPATWASIIRHGDATDVRGIIQKIVDSHK
VKHVACYGFRLSHLRSEEVHWLHLDMGVSNVREKYELAHPPEEWKYELRIRYLPKGFLNQ
FTEDKPTLNFFYQQVKSDYMSEIADRVDQDIALKLGCLEIRRSYWEMRGNALEKKSNYEV
LEKDVGLKRFFPRSLLDSVKAKTLRKLIQQTFRQFANLNREESILKFFEILSPVYRFDKE
CFKCALGSSWIISVELAIGPEEGISYLTDKGCSPTHLADFNQVQTIQYSNSEDKDRKGTL
QLKIAGAPEPLTVTAPSLTIAENMADLIDGYCRLVNGATQSFIIRPQKEGERALPSIPKL
ANSEKQGVRTHAVSVSGIYPDITHSAARALTWASRSVPSLGALATSPSPLTLLSPCPTSL
LLETDDYAEIIDEEDTYTMPSKSYGIDEARDYEIQRERIELGRCIGEGQFGDVHQGVYMS
PENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLVGVITENPVWIIMELCT
LGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLG
DFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPF
QGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEE
KVQQEERMRMESRRQVTVSWDSGGSDEAPPKPSRPGYPSPRSSEGFYPSPQHMVQTNHYQ
VSGYPGSHGVTATAGSIYPGQASLLDQTDSWNHRPQEISMWQPNVEDSAALDLRGIGQVL
PTQLVEERLIRQQQEMEEDQRWLEKEERFLVILKPDVRLSRGSIDREDGSLQGPTGNQHI
YQPVGKPDPAAPPKKPPRPGAPGHLGSLASLSSPGDSYNEGVKPWRLQPQEISPPPTANL
DRSNDRVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETLPVLPA
STHREIEMAQKLLNSDLGELINKMKLAQRCAMTSLQQDHKKQMLTAAHALAVDAKNLLDV
IDQARLRALGHARPR
NT seq
3468 nt
NT seq
+upstream
nt +downstream
nt
atgttggtggaactggcgggccgagaggccctgagaccagcaggtgccgtctgtatggag
aagagcggctgtggtccatttccagtgtgttgggctaaagattatgacagatacatagca
ccaagcaaaataatggcagctgcttaccttgacccaaacttgaatcacaccccgaattcg
agtaccaagacccatctgggtaccggagtggaacgttcccccggggcaatggagcgagtg
ttgaaggtctttcattattttgagaacagcagtgagccagccacttgggccagtattatc
aggcacggagatgctactgatgtcaggggcatcattcagaagatagtggacagtcacaaa
gtaaagcacgtggcctgctatggatttcgcctcagtcacctgcggtcagaggaggttcac
tggctccatttggatatgggtgtctccaatgtgagggagaagtatgaacttgcacaccca
ccagaggagtggaaatatgaattgagaattcgttatttgccaaaaggatttctaaaccag
tttactgaagacaagccaactctgaatttcttctatcaacaggtgaaaagtgactacatg
tcggagatagctgaccgggtggaccaggacatcgctttgaagctgggctgcctagaaata
cggcgctcgtattgggagatgcgaggcaacgcgctagagaagaagtccaactatgaggtg
ttagaaaaagatgttggtttgaagcgattttttcctaggagtttactggattctgtcaag
gccaaaacactaagaaaactgatccagcagacatttagacagttcgccaacctgaacaga
gaagagagcattctgaaattctttgagatcctctccccagtgtaccgatttgataaagag
tgcttcaagtgtgccctcggttcaagctggattatttcagtggaactggcgatcggccca
gaagaaggaatcagttacctcacggacaagggctgcagccccacacatctggccgacttc
aatcaagtgcagaccattcagtattccaacagcgaagacaaggacaggaaaggaacgctg
cagctgaaaatcgcgggcgcccccgagcctctgacagtgacagcaccgtccctgaccatc
gccgagaatatggctgacctgatagatgggtactgccggctggtgaacggagccacgcag
tcctttatcatcaggccccagaaagaaggtgaacgggctttgccatcaataccaaagctg
gccaacagcgagaagcaaggcgtgcggacacacgcggtctccgtgtcaggcatctaccct
gacatcactcacagcgcagccagagccctgacgtgggcttctaggtctgtgccatcactg
ggagcactggccacctctccctcacccctcactcttttgtcaccctgcccaacctcattg
ctcctcgaaaccgacgactatgctgagattatagacgaagaagatacctacaccatgccc
tcaaaaagctatggaatagacgaagccagggactacgagattcaaagagaaaggatcgag
cttggacggtgcatcggggaaggccagtttggggacgtccaccaaggcgtctacatgagt
ccagagaatccggctttggcggtcgcaattaaaacatgtaaaaactgtacttcggacagc
gtgcgagagaaattccttcaagaagccttaacgatgcgccagtttgaccacccccacatc
gtgaagctggtcggtgtcatcacggagaaccccgtctggataatcatggagttgtgcacg
cttggagagctgaggtcgtttctgcaagtgaggaagtacagtttggatctcgcgtctttg
atcctgtatgcctatcagcttagtacagctctggcgtatctggagagcaaaagattcgtg
cacagggacattgctgctcggaatgttctggtgtcctcaaacgattgcgtaaaattagga
gactttggattatcccggtatatggaagacagtacttactacaaagcttccaaaggaaag
ttgcctattaaatggatggctccagagtccatcaactttcgacgttttacctcagccagt
gacgtgtggatgtttggtgtgtgtatgtgggagatactgatgcatggtgtgaagccgttt
caaggagtgaagaacaatgatgtgatcggtcgaatcgagaacggggagagattaccaatg
cctccaaattgccctcccaccctctacagccttatgacgaaatgctgggcctatgacccc
agcaggcggccccggttcactgagctcaaagctcagctcagcaccatcctggaggaggag
aaggttcagcaagaagaacgaatgaggatggaatcccgaagacaggtcacagtgtcctgg
gactccggagggtccgacgaagcgccacccaagcccagcagacctggttaccccagtccg
cggtccagcgaaggattttatcccagtccccagcacatggtacagaccaatcattaccag
gtgtctggctatcctggttcacatggggtcacagccacggctggcagcatctacccgggt
caggcatctcttttggaccagacggactcatggaatcacagaccacaggagatatcgatg
tggcagcccaacgtggaggactctgcggccctggacctgcgcgggatcgggcaggtgctg
cccacccagctggtggaagagcggctgatccggcagcagcaggaaatggaggaggaccag
cgctggctcgagaaagaggagagattcctggtcatcctgaaacccgacgtgcggctctct
cgaggcagcatcgacagggaggacgggagtcttcagggcccgacgggaaaccaacacatc
tatcagcctgtgggtaaaccagatcccgcagctccgccaaagaaaccgccgcggcctgga
gcccccggtcacctgggcagcctcgccagcctcagcagccccggggacagttacaacgag
ggcgtcaagccatggaggcttcagccccaggaaatcagccccccgcccactgccaacctg
gaccggtccaacgacagggtgtacgagaatgtgacgggcctggtgaaggctgtcatcgaa
atgtccagcaagatccagccagcccccccggaggagtacgttcccatggtgaaggaagtc
ggcctggccctgcggacattactggccaccgtggacgagacccttccagtcctgccagcc
agcactcaccgagagatcgagatggcccagaagctgttgaactccgacctgggcgagctc
atcaacaagatgaagctggcccagcggtgcgccatgaccagcctacagcaggaccacaag
aagcagatgctgaccgccgcccacgccctggccgtggacgccaagaacttactcgacgtc
atcgaccaggccagactgagggcactcggacacgcgaggccgcgctga
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integrated database retrieval system
