Panthera pardus (leopard): 109276748 Help Entry 109276748         CDS       T06062                                  Symbol FASN Name (RefSeq) fatty acid synthase isoform X1   KO K00665   fatty acid synthase, animal type [EC:2.3.1.85] Organism ppad  Panthera pardus (leopard) Pathway ppad00061   Fatty acid biosynthesis ppad01100   Metabolic pathways ppad01212   Fatty acid metabolism ppad04152   AMPK signaling pathway ppad04910   Insulin signaling pathway ppad04936   Alcoholic liver disease Module ppad_M00082   Fatty acid biosynthesis, initiation ppad_M00083   Fatty acid biosynthesis, elongation Brite KEGG Orthology (KO) [BR:ppad00001]  09100 Metabolism   09103 Lipid metabolism    00061 Fatty acid biosynthesis     109276748 (FASN)  09130 Environmental Information Processing   09132 Signal transduction    04152 AMPK signaling pathway     109276748 (FASN)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     109276748 (FASN)  09160 Human Diseases   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     109276748 (FASN)  09180 Brite Hierarchies   09181 Protein families: metabolism    01004 Lipid biosynthesis proteins [BR:ppad01004]     109276748 (FASN)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:ppad04147]     109276748 (FASN) Enzymes [BR:ppad01000]  2. Transferases   2.3  Acyltransferases    2.3.1  Transferring groups other than aminoacyl groups     2.3.1.85  fatty-acid synthase system      109276748 (FASN) Lipid biosynthesis proteins [BR:ppad01004]  Fatty acid synthase   Animal type    109276748 (FASN) Exosome [BR:ppad04147]  Exosomal proteins   Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)    109276748 (FASN)   Exosomal proteins of breast milk    109276748 (FASN)   Exosomal proteins of colorectal cancer cells    109276748 (FASN)   Exosomal proteins of bladder cancer cells    109276748 (FASN) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Acyl_transf_1 ketoacyl-synt Thioesterase KR Ketoacyl-synt_C KAsynt_C_assoc FAS_pseudo-KR ADH_zinc_N_2 ADH_zinc_N PKS_DH_N PP-binding Methyltransf_12 adh_short PS-DH Methyltransf_23 Methyltransf_11 Methyltransf_31 Thiolase_N ACP_SdgA_C Methyltransf_25 Motif Other DBs NCBI-GeneID:  109276748 NCBI-ProteinID:  XP_019321387 LinkDB All DBs Position Unknown AA seq 2546 aa AA seqDB search MEDVVIAGMSGKLPESENMEEFWANLIGGVDMVTDDDRRWKAGLYGLPKRTGKLKDLSKF DASFFGVHPKQAHTMDPQLRLLLEVTYEAILDGGINPATLRGTHTGVWVGVSGSEASEAL SRDPETLLGYSMVGCQRAMMANRLSFFFDFKGPSIALDTACSSSLLALQNAYQAIRRGEC PAAIVGGLNILLKPNTSVQFMKLGMLSPDGTCKAFDESGDGYCRAEAVVAVLLTKKSLAR RVYATILNAGTNTDGCKEQGVTFPSGEAQEQLIRSLYEPAGLSPESLEYIEAHGTGTKVG DPQELNGIAQVLCPSRQEPLLIGSTKSNMGHPEPASGLAALAKVLLSLEHGLWAPNLHFR SPNTEIPALQDGRLQVVQQPLPVRGGNVCINSFGFGGSNVHVILQPNPRLPSAPTRHASL PRLLRASGRTPEAVHCLLEQGHRHSQDLAFVSMLNDIAAIPPTAMPFRGYTVLGGKGGSQ EVQQVAAGKRPLWFICSGMGAQWCGMGLSLMRLGSFRDSILRSDEAVKPLGLQVSELLLS TDEATFDDIVHAFVSLTAIQIALIDLLNSMGLRPDGIIGHSLGEVACGYADGCLSQEEAI LAAYWRGQCIKETNIPPGTMAAVGLSWEECKQRCPPGVVPACHNSEDTVTISGPQAEVAA FVAELKQEGVFAKEVRTGGMAFHSYFMDSIAPTLLQALKKVIREPRPRSARWLSTSIPEA QWQGSLARTFSAEYNVNNLVSPVLFQEALWHVPGDAVVLEIAPHALLQAVLKRGLKSSCT IIPLMKKDQRDNLEFFLSNVGKLHLLGFDVNPNGLLPPVEFPVPRGTPLISPHIKWDHSQ TWDVPTAKDFPSGSSGSSASTVCNISVSPESPDHYLVDHCIDGRVLFPATGYLCLVWKTL ARTLSQNMEQVPVVFEDVTLHQATVLPKTGTVPLEVRLLQASRTFEVSENGNLIVSGKVY QWEDPDAKLFDSRDGPDTTDPTATFRLSQRDVYKELRLRGYDYGPHFQGILEANLEGNAG RLLWKNNWVTFLDTMLQTSILGLAQCGLRLPTRITSVRIDPATHQHRVYSLLGGAQVVNV VVNSCLNSTVAGGVLISGLHASMAPRRQQEQFAPILEKFCFTPHTEEGLLAGDTALQEGL QLCRGLARALQTKVAQQGLKMVVSGLDGAQAPQEPPKQGLPRLLAAACQLQLNGGLQLEL GQLLAQQRPLLQDDPLLSGLLASPALKACVDTALENMPSLKMKVVEVLAGDGHLYSHVPA LLNTQPMLQLEYTATDRHPQALEAVQAKLQQHGIAQGQWDPADPAPGSLGSADLLLCNCA VASLGDPATAVGNMGAALKEGGFLLLHALLKGHPLGETVAFLTCPEPRQGQQSLLSQDEW ESLFAGASLHLVALKRSFYGSVLFLCRRPVLQDSPVFLPVEDPSFQWVNSLKNILADSSQ QPVWLTATSCPDSGVVGLVNCLRREPGGHRIRCILVSNLSSTSRTPSLDPGSSELQKVLR GDLVMNVYRDGAWGAFRHFPLERGLPEEQTEHAFVNVLTRGDLSSIRWVCSPLRHTQLTG PGVQLCAVHYASLNFRDIMLATGKLSPDAIPGKWALRNCLLGMEFSGRDASGKRVMGLVP AEGLATSVLLSQDFLWEVPSSWTLEEAASVPVVYTTAYYSLVVRGRMQPGETVLIHSGSG GVGQAAIAIALSLGCRVFTTVGSAEKRAYLQARFPQLDDTSFANSRDTSFEQHVLRHTAG KGVDLVLNSLAEEKLQASVRCLAQHGRFLEIGKFDLSNNHLLGMAVFLKNVTFHGVLLDS LMDEGGNSWQEVAALLKAGIRDGVVQPLKCTVFPKDRVEDAFRYMAQGKHIGKVVIQVRR GPGSPGSPRSPRSSPRGSARARLLLGLQVRREEPEAVLRETGPALMAAVSRTYCPAHKSY VITGGLGGFGLELAQWLVLRGARKLVLTSRSGIRTGYQAKQVREWRRQGIQVLVSTSNAS SLDGAQSLIDEATQLGPVGGVFNLAVVLRDAMLENQTPELFQDVNRPKYSGTVNLDRVTR TACPELDYFVAFSSVSCGRGNAGQTNYGFANSTMERVCEKRQHDGLPGLAIQWGAIGDVG IILESMGSNDTVIGGTLPQRIASCLEVLDLFLNQPHPVLSSFVLAEKKATAHDDGSGQQD PMEAVAHILGIRDLATVNLDSSLADLGLDSLMGVEVRQMLEREHDLVMSMRDIRQLTLRK LQELSSKAGTANELAAPTPKEDTPAGQQAQLNLSTLLVNPEGPTLTRLNSVQSSERPLFL VHPIEGSITVFHSLASKLSIPTYGLQCTRAAPLDSIQSLAAYYIECIRQVQPEGPYRIAG YSYGACVAFEMCSQLQAAQQGPTPAHNSLFLFDGSHAYVLAYTQSYRAKLTPGCEAEAEA EAMCFFLQQFTDMEHNRVLETLLPLEGLEERVAATVDLITRSHAGLDPRELSFAARSFYH KLRAAEQYTPRATYHGNVTLLRAKTGSVYGEGLGADYNLSQVCDGKVSVHVIEGDHRTLL EGSGLETILSIIHSSLAEPRVSVREG NT seq 7641 nt NT seq  +upstreamnt  +downstreamnt atggaggacgttgtgattgctggcatgtccgggaagctgcccgagtcggagaacatggag gagttctgggccaacctcatcggcggcgtggacatggtgacagacgatgacaggaggtgg aaggcaggactctacggcctgcccaagcgtaccggcaagctaaaggacctgtccaagttc gatgcctccttcttcggggtccacccaaagcaggctcacacgatggacccccagctgcgc ttgctactggaggtcacctacgaggccatcctggatggaggcatcaacccggctaccctg cgagggacacacacaggcgtctgggtgggcgtgagtggctcggaggcctcagaggctctg agccgagaccccgagactctcctgggctacagcatggtgggctgccagagggctatgatg gccaaccgcctctcctttttctttgattttaaagggcccagcatcgctctggacacagcc tgctcctccagcctgctggcccttcagaacgcctaccaggccatccgcaggggagagtgc cccgcagccatcgtgggcggcctcaacatcctgctcaagcccaacacctccgtgcagttc atgaagctcggcatgctgagccccgacggaacctgcaaggccttcgacgagtccggggac ggctactgccgtgcggaggccgtggtggccgtcctgctgaccaagaagtccctggcccgg cgtgtgtatgccaccatcctcaacgccggcaccaacacggacggctgcaaggagcaaggt gtgaccttcccctccggggaggcgcaagaacagctcatccgctcgctgtacgagccggct gggttgagcccagagtccctcgagtatatcgaagcccacggcacagggaccaaggtgggg gacccccaggagctgaacggtatcgcccaagtcctgtgtccctcccgccaggagcccctg ctgatcgggtccaccaagtcgaacatggggcacccggagcccgcttcagggctcgcggct ctggccaaggtgctgctgtccctggagcatgggctctgggcccccaacctgcacttccgg agcccgaacaccgagatccctgcgctccaggacggacggctgcaggtggtgcagcagccc ctgcccgtccgcggaggcaacgtgtgtatcaattcgttcggcttcggcggctccaacgtg cacgtcattctccagcccaatccgcggctgccctcggcccccacccggcacgcctctctg ccccgtctgctgcgggccagcggacgcaccccggaggccgtgcactgcctgctggagcaa ggccaccggcacagccaggacctggccttcgtgagcatgctcaatgacatcgcagccatc ccccccaccgccatgcccttccggggctacaccgtgctgggtggcaagggcggcagccag gaggtacagcaggtggccgctggcaagcgtccgctctggttcatctgctcggggatgggc gcacagtggtgcgggatgggattgagcctcatgcgcctgggcagcttccgggactccatc ctgcgctccgacgaggccgtgaagcccttgggactgcaggtgtctgagctgctgctgagc acagatgaggccacctttgatgacatcgtccacgccttcgtgagcctcaccgccatccag atcgccctcatagacctgctgaactccatgggtctgcggcccgacggaatcatcgggcac tccctgggtgaggtggcctgtggctacgcagatggctgcctttctcaggaggaggccatc ctcgccgcctactggaggggccagtgcatcaaggagaccaacatcccaccggggaccatg gcggccgtcggcttgtcctgggaggagtgtaagcagcgctgcccccctggtgtcgtgccc gcctgccacaactctgaggacacagtgaccatctcgggaccgcaggccgaggtggctgca ttcgtggcggagctgaagcaggagggtgtgtttgccaaggaggtgcggacgggcggcatg gccttccactcctacttcatggactccatcgcccccacattgcttcaggccctcaagaag gtgatccgggagccgcggccccgctcggcacgctggctcagtacctccatccccgaggcc cagtggcagggcagcctggcccgcacgttctcggcggagtataacgtcaacaatctggtg agccccgtgctgttccaggaggcgctgtggcatgtgcccggggacgccgtggtgttggag atcgccccccacgccctgctgcaggccgtcctcaagagaggcctgaagtccagctgtacc atcattcctctgatgaagaaggaccaaagagacaacctggagttcttcctcagcaacgtg ggcaagttgcatctgctgggcttcgatgtcaaccccaatggcctgcttccacccgtggag ttcccggtgccccggggcactcctctcatctcccctcacatcaagtgggaccacagtcag acctgggacgtccccaccgccaaggacttccccagcggctccagtggctcctctgcctcc accgtctgcaacatcagcgtcagccctgaatcccctgaccactacctggtggaccactgc atcgacggccgcgtcctcttccccgccaccggctacctgtgcctggtctggaagactctg gcacggaccttgagtcaaaacatggaacaagtacccgtggtgtttgaggacgtgacactg caccaggctactgtcctacccaagaccgggaccgtgcccctggaagtgcggctcctacag gcttcccgtaccttcgaggtgtctgagaacggcaacctgatagtgagcgggaaggtttac cagtgggaggaccccgatgccaagctgttcgacagccgggacggcccggacaccacggac cccacagctacgttccgcctgagccagagggacgtgtacaaagagttgaggctgcgtggc tatgactacggccctcattttcaaggcatcctcgaggccaacctcgaaggcaacgcgggc cggctgctgtggaagaacaactgggtgacgttcctggacaccatgctgcagacatccatc ctgggcctggcccagtgcggcctgcgtctgcccacccgcatcacctctgtccgcatcgac cccgccacccaccagcacagggtgtactcgctgctgggcggggcccaagtggtcaacgtg gtggtgaacagttgtctgaacagcacggtggccggcggcgtcctcatctcgggcctccac gcctcgatggccccacggcggcagcaggagcagtttgcgcccatcctggagaagttctgt ttcacgccgcacacggaggaggggctcctggctggagacacggccctgcaggaggggctg cagctgtgcagggggctggcacgggcgctgcagaccaaggtggcccagcaggggctgaag atggtggtgtctgggctggacggggcccaggccccccaggagcctccaaagcaaggcctg ccccggctgctggcggccgcctgccagctgcagctcaacggcggcctccagctggagctg ggccagctgctggcccaacagaggcccctgctgcaggacgaccccctgctcagcggcctc ctcgcttccccggcgctcaaagcctgcgtggacacagccctggagaacatgcccagcctc aagatgaaggtcgtggaggtgctggctggcgatggccacctgtattctcacgtcccggcg ctgcttaacacccagcccatgctgcagctggagtacacggccactgaccgccaccctcag gccctggaggccgtgcaggccaagctgcagcagcacggcatagcccagggccagtgggac cctgcagaccccgcccctggcagcctgggctcagctgatctcctcctgtgtaactgtgcg gtggccagcctcggtgacccggccacggccgttggcaacatgggggccgctctcaaggag ggcggcttcctgctgctgcacgctctgctcaaaggacacccccttggagagacggtcgcc ttcctcacctgccccgagccgcggcaaggccagcagagcctcctaagccaggacgagtgg gagagtctgtttgccggggcgtccctgcacctggtggccctgaagaggtccttctacggc tctgtgctcttcctgtgccgtcggccggtcctacaggacagccctgtcttcctgcctgtg gaggaccccagtttccagtgggtgaactccctgaagaacattttggccgactcctcccag cagcccgtgtggctaacagccaccagctgccccgactcaggcgtcgtgggcttggtgaac tgtctccgcagagagcctggcgggcaccggattcggtgcatcctggtgtccaacctcagc agcacgtcccgcacccccagtttggaccccggctcctcggagctgcagaaggtgctacgg ggggacctcgtgatgaatgtctaccgagacggggcctggggggccttccgccatttcccc ctggagcgcggcctgccagaggagcagaccgagcacgccttcgtgaacgtcctcacgcgg ggggacctctcctccatccgctgggtctgctcccctctgcgtcacacccagctcaccggc cccggcgtccagctctgtgccgtccactatgcctccctcaacttcagagatatcatgctg gccacgggcaagctgtcccctgacgccatcccagggaagtgggccctccgcaactgtttg ctgggcatggagttctctggccgagacgccagcggcaagcgtgtcatggggctggtgccc gctgaaggcctggctacctccgtcctgctctctcaggacttcctgtgggaggtgccctcc agctggaccctagaggaggcggcttcggtgcctgtggtctacaccaccgcctactactcg ctggtggtgcgggggcgcatgcagcccggggagacggtgctcatccactcaggctcgggc ggcgtgggccaggccgccatcgccatcgccctcagcctgggctgccgcgtcttcactacc gtggggtcagccgagaagcgggcgtacctccaggccaggttcccccagctcgacgacacc agcttcgccaactcccgggacacgtcctttgaacagcacgtgctgcggcacacagcaggg aagggtgtggacctggtcctgaattctctggcagaagaaaagctacaggccagcgtgcgg tgcctggcccagcacggccggttcctggaaatcggcaaattcgacctttcgaacaaccac ctgctgggcatggccgtcttcctgaagaacgtgaccttccacggggtcctgctggattcg ctcatggatgaaggcgggaacagctggcaggaggtggctgcgctgctgaaggcgggcatc cgggacggcgtggtgcagcccctcaagtgcaccgtgttccccaaggaccgggtggaggac gccttccgctacatggcccaagggaaacacatcggcaaagtggtcatccaggtgaggagg gggcccggctcccccggctccccccgctccccccgctccagccccaggggcagcgctcga gcacggctgctgctcggactgcaggtgcgcagggaggagccggaggcggtgctgcgggag acgggtcccgccctgatggccgccgtgtccaggacctactgcccggcccacaagagctat gtcatcaccgggggcctgggcggcttcggcctggagctggcccagtggcttgtgctgcga ggggcccggaaactcgtgctgacctctcgctctgggatccgcacaggctaccaggccaag caggtccgtgagtggaggcgccagggcatacaggtcctggtgtccaccagcaacgccagc tcgctggatggggcccagagcctcatcgatgaggccacgcagctggggcccgtgggaggc gtctttaacctggccgtggtcctgagagacgccatgctggagaaccaaacccctgagctc tttcaggacgtcaacaggcccaagtacagcggcaccgtgaacctggacagggtgacccga actgcgtgccccgagctggactactttgtggccttctcctccgtgagctgcgggcgcggc aacgccggccagaccaactatggcttcgccaactccaccatggagcgcgtgtgtgagaag cgccagcacgacggcctcccgggcctcgccattcagtggggcgccatcggtgacgtgggc atcatcctggagtccatgggctccaacgatacggtcatcggcgggacgctgccgcagcgg attgcctcctgcttggaggtgctggacctcttcctgaaccagccccaccccgtcctgagc agctttgtgctggccgagaagaaggccactgcccacgatgacggcagtggccagcaggac ccgatggaggccgtggcccacatcctgggcatccgagacttggccaccgtcaacctggac agctcgctggcagacctgggtctggactcgctcatgggcgtggaggtgcgccagatgttg gagcgcgagcacgacctggtgatgtccatgcgggacatccggcagctcacgctccggaag ttgcaggagctttcctcgaaggctggcacagccaatgagctggcagcccccacacccaag gaggacacccctgccggccagcaggcccagctgaacctcagcaccctgctggtgaacccc gagggcccgaccttgacacggctcaactcggtgcagagctctgagcgccccctgttcctg gtgcaccccatcgagggctccatcactgtgttccacagcctggcgtccaagctcagcatc cccacctacggcctacagtgcactcgagccgcgcccctggacagcatccagagcctggcc gcctactacatcgagtgcatcaggcaggtgcagccggaggggccctaccgcatcgccggc tattcctacggggcctgcgtggccttcgagatgtgctcgcagctgcaggccgcgcagcag ggccccacccccgcgcacaacagcctcttcttgttcgacggttcgcacgcctatgtgctg gcctacacgcagagctaccgcgcgaagctcacccctggctgtgaggccgaggccgaggcc gaggccatgtgcttcttcctgcaacagttcaccgacatggaacacaacagggtgctggag acgctgctgcccctcgagggcctggaggagcgcgtggcggccaccgtggacttgatcacg cgcagccacgcgggcctggacccccgcgagctgagcttcgcggcgcgctccttctaccac aagctgcgcgcggccgagcagtacaccccccgggccacctaccacggcaacgtgacgctg ctgcgcgccaagacgggcagcgtgtacggcgagggcctgggcgccgactacaacctgtcc caggtgtgcgacggcaaggtgtccgtgcacgtgatcgagggggaccaccgcacgctgctg gagggcagcggcctggagactatcctcagcatcatccacagctccctggccgagccgcgc gtcagcgtccgggagggctaa

DBGET integrated database retrieval system