Panthera pardus (leopard): 109279193 Help Entry 109279193         CDS       T06062                                  Symbol TRAF6 Name (RefSeq) TNF receptor-associated factor 6   KO K03175   TNF receptor-associated factor 6 [EC:2.3.2.27] Organism ppad  Panthera pardus (leopard) Pathway ppad04010   MAPK signaling pathway ppad04064   NF-kappa B signaling pathway ppad04120   Ubiquitin mediated proteolysis ppad04140   Autophagy - animal ppad04144   Endocytosis ppad04380   Osteoclast differentiation ppad04620   Toll-like receptor signaling pathway ppad04621   NOD-like receptor signaling pathway ppad04622   RIG-I-like receptor signaling pathway ppad04657   IL-17 signaling pathway ppad04722   Neurotrophin signaling pathway ppad04936   Alcoholic liver disease ppad05132   Salmonella infection ppad05133   Pertussis ppad05135   Yersinia infection ppad05140   Leishmaniasis ppad05142   Chagas disease ppad05145   Toxoplasmosis ppad05152   Tuberculosis ppad05160   Hepatitis C ppad05161   Hepatitis B ppad05162   Measles ppad05168   Herpes simplex virus 1 infection ppad05169   Epstein-Barr virus infection ppad05170   Human immunodeficiency virus 1 infection ppad05171   Coronavirus disease - COVID-19 ppad05200   Pathways in cancer ppad05222   Small cell lung cancer ppad05235   PD-L1 expression and PD-1 checkpoint pathway in cancer ppad05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:ppad00001]  09120 Genetic Information Processing   09123 Folding, sorting and degradation    04120 Ubiquitin mediated proteolysis     109279193 (TRAF6)  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     109279193 (TRAF6)    04064 NF-kappa B signaling pathway     109279193 (TRAF6)  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     109279193 (TRAF6)    04140 Autophagy - animal     109279193 (TRAF6)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     109279193 (TRAF6)    04621 NOD-like receptor signaling pathway     109279193 (TRAF6)    04622 RIG-I-like receptor signaling pathway     109279193 (TRAF6)    04657 IL-17 signaling pathway     109279193 (TRAF6)   09156 Nervous system    04722 Neurotrophin signaling pathway     109279193 (TRAF6)   09158 Development and regeneration    04380 Osteoclast differentiation     109279193 (TRAF6)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     109279193 (TRAF6)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     109279193 (TRAF6)   09162 Cancer: specific types    05222 Small cell lung cancer     109279193 (TRAF6)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     109279193 (TRAF6)    05161 Hepatitis B     109279193 (TRAF6)    05160 Hepatitis C     109279193 (TRAF6)    05171 Coronavirus disease - COVID-19     109279193 (TRAF6)    05162 Measles     109279193 (TRAF6)    05168 Herpes simplex virus 1 infection     109279193 (TRAF6)    05169 Epstein-Barr virus infection     109279193 (TRAF6)   09171 Infectious disease: bacterial    05132 Salmonella infection     109279193 (TRAF6)    05135 Yersinia infection     109279193 (TRAF6)    05133 Pertussis     109279193 (TRAF6)    05152 Tuberculosis     109279193 (TRAF6)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     109279193 (TRAF6)    05140 Leishmaniasis     109279193 (TRAF6)    05142 Chagas disease     109279193 (TRAF6)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     109279193 (TRAF6)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     109279193 (TRAF6)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:ppad04131]     109279193 (TRAF6)    04121 Ubiquitin system [BR:ppad04121]     109279193 (TRAF6) Enzymes [BR:ppad01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.27  RING-type E3 ubiquitin transferase      109279193 (TRAF6) Membrane trafficking [BR:ppad04131]  Endocytosis   Clathrin-mediated endocytosis    Ubiquitin E3 ligases     109279193 (TRAF6) Ubiquitin system [BR:ppad04121]  Ubiquitin ligases (E3)   Single Ring-finger type E3    TRAF proteins     109279193 (TRAF6) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  TRAF-mep_MATH MATH_2 zf-TRAF TRAF6_Z2 zf-C3HC4_2 zf-C3HC4 zf-RING_UBOX zf-RING_2 zf-C3HC4_4 zf-C3HC4_3 zf-TRAF_2 zf-RING_5 U-box TRAF3_RING RING_XB3-XBAT31 Med21 DUF4455 zf-RING_11 Spc29 SlyX Laminin_I Sina_ZnF DUF16 EzrA DUF1664 Motif Other DBs NCBI-GeneID:  109279193 NCBI-ProteinID:  XP_019325681 Ensembl:  ENSPPRG00000014400 UniProt:  A0A9V1GMU7 LinkDB All DBs Position Unknown AA seq 541 aa AA seqDB search MSLLNCENSCGSSQSESGCCAAMASSCSAAAKDDSVSGTASTGNLSSSFMEETQGYDVEF DPPLESKYECPICLMALREAVQTPCGHRFCRACIIKSIRDAGHKCPVDNEILLENQLFPD NFAKREILSLMVKCPNEGCLHKMELRHLEDHQAHCEFALMNCPQCQRPFQKCQLNIHILK ECPRRQVSCVNCAALMAFEDKEIHDQNCPLANVICEYCNTMLIREQMPNHYDLDCPTAPI PCTFSTFGCHVKMQRNHLARHLQENTQSHMRMLAQAVQSLSLALPPVPQCDMPPYDSSSV SRVSTGCHPEVQNFQETIQQLEGRLVRQDHQIRELIAKMETQSMYVSELKQTIRTLEDKV VEIEAQQCNGIYIWKIGNFGMHLKSQEEEKPVVIHSPGFYTGKPGYKLCMRLHLQLPSAQ RCANYISLFVHTMQGEYDSHLPWPFQGTIRLTILDQSEAPIRQNHEEIMDAKPELLAFQR PTIPRNPKGFGYVTFMHLEALRQRTFIKDDTLLVRCEVSTRFDMGSLRREGFQPRSTDSG M NT seq 1626 nt NT seq  +upstreamnt  +downstreamnt atgagtctgctaaactgtgaaaacagctgcggatccagccagtctgagagtggctgctgt gccgccatggccagctcctgtagcgctgcggcgaaagatgacagtgtgagtggaaccgcc agcacggggaacctctccagctctttcatggaagagacccaggggtatgacgtggagttt gacccgcccctggagagcaagtatgagtgccccatctgcctgatggctctccgggaggca gtgcagacaccgtgcggccacaggttctgcagagcttgcatcatcaaatcaataagggat gcaggtcacaaatgtccagttgacaatgaaatactgctggaaaatcaactatttcctgac aattttgcaaaacgagagattctttctctgatggtgaaatgtccaaatgaaggttgtttg cacaagatggaactgaggcatcttgaggatcaccaagcacattgtgaatttgctcttatg aattgtcctcagtgccagcgtcccttccaaaaatgccaacttaacattcacattctcaag gagtgtccaaggagacaggtttcttgtgtaaactgtgctgcattgatggcatttgaagat aaagagatccacgaccagaactgtcctttggcaaatgtcatctgtgaatactgcaatacc atgctcatcagagaacagatgcctaatcattacgacctggactgtcctacagccccaatt ccatgcacattcagtacttttggttgccatgtaaagatgcagaggaatcacttggcacgc cacctgcaagagaatacccagtcgcacatgagaatgttggcccaggctgttcagagttta agccttgcgttacctcctgtacctcagtgtgatatgcctccatacgattcttcctctgtg tcccgggtttccactgggtgtcacccagaggtccagaatttccaagaaaccattcagcag ttagagggtcgccttgtaagacaagaccatcaaatccgagagctaattgctaaaatggaa actcagagcatgtacgtaagtgagctcaaacaaacgattcgaacccttgaggacaaagtt gttgaaatagaagcacagcagtgcaatgggatttacatctggaagattggcaactttggg atgcatttgaaatctcaagaagaggagaaacctgttgtcattcatagccctggattctac acaggcaaacccgggtacaaactgtgcatgcgcctgcaccttcagttaccgtcggctcag cgctgtgctaattacatatccctctttgtgcacacaatgcaaggagagtatgacagccac ctcccttggcccttccaaggtacaatccgccttacaattcttgatcagtctgaggcacct ataaggcaaaaccatgaagagatcatggatgccaaaccagagctgcttgccttccagaga cccacaatcccacggaacccaaaaggttttggctatgtgacttttatgcatctggaagcc ctgagacagagaaccttcattaaggacgatactttattagtgcgctgtgaggtctctacc cgctttgacatgggtagtctccggagggagggttttcagccacgaagtactgattcaggg atgtag

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