Pteronotus mesoamericanus (Parnell's mustached bat): 129074836
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Entry
129074836 CDS
T09558
Symbol
JAK3
Name
(RefSeq) tyrosine-protein kinase JAK3
KO
K11218
Janus kinase 3 [EC:
2.7.10.2
]
Organism
ppam
Pteronotus mesoamericanus (Parnell's mustached bat)
Pathway
ppam04062
Chemokine signaling pathway
ppam04151
PI3K-Akt signaling pathway
ppam04217
Necroptosis
ppam04550
Signaling pathways regulating pluripotency of stem cells
ppam04630
JAK-STAT signaling pathway
ppam04658
Th1 and Th2 cell differentiation
ppam04659
Th17 cell differentiation
ppam05161
Hepatitis B
ppam05162
Measles
ppam05166
Human T-cell leukemia virus 1 infection
ppam05169
Epstein-Barr virus infection
ppam05200
Pathways in cancer
ppam05203
Viral carcinogenesis
ppam05223
Non-small cell lung cancer
ppam05340
Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:
ppam00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
129074836 (JAK3)
04151 PI3K-Akt signaling pathway
129074836 (JAK3)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
129074836 (JAK3)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
129074836 (JAK3)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
129074836 (JAK3)
04659 Th17 cell differentiation
129074836 (JAK3)
04062 Chemokine signaling pathway
129074836 (JAK3)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
129074836 (JAK3)
05203 Viral carcinogenesis
129074836 (JAK3)
09162 Cancer: specific types
05223 Non-small cell lung cancer
129074836 (JAK3)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
129074836 (JAK3)
05161 Hepatitis B
129074836 (JAK3)
05162 Measles
129074836 (JAK3)
05169 Epstein-Barr virus infection
129074836 (JAK3)
09163 Immune disease
05340 Primary immunodeficiency
129074836 (JAK3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ppam01001
]
129074836 (JAK3)
Enzymes [BR:
ppam01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
129074836 (JAK3)
Protein kinases [BR:
ppam01001
]
Non-receptor tyrosine kinases
JAK family [OT]
129074836 (JAK3)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
SH2_1
FERM_F1
Jak1_Phl
Kinase-like
ABC1
Kdo
FERM_M
SH2
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
129074836
NCBI-ProteinID:
XP_054434689
LinkDB
All DBs
Position
Unknown
AA seq
1104 aa
AA seq
DB search
MAPPSEETPLISQRSCSLSSSETGALHVLLPPRGPGPPQRLSFSFGDHSAEELCVQAAKA
SGILPVYHSLFALAVEDLSCWFPPSHIFSVEDVGTQVLVYRLRFYFPDWFGLEKCHRFGL
RKDLASAILDLPVLEHLFAQHRHDLVSGRLSVGLSLKEQGECLSLAVLDLARMACEQAQR
PEELLKTISYKTCLPPSLRDLIQGLSFVTRRRIRRRVRQALCRVATCQVDRHSLMVKYIM
DLERLDPTRATETFLVGLPGAAGGQDASGLLRVSGGSGITWSPGPQEVFQPFCDFPEIVD
ISIKQAPRVGPAGEHRLVTVTRTDNQILEAEFPGLPAALSFVALVDGYFRLTTDSRHYFC
KEVAPPRLLEEVAQQCHGPITLDFAINKLKTEGSLPGSYVLRRSPQDFNSFLLTVCVQTP
LGPDYKGCLIRCDPTGTFSLAGLGRPHSSLRELLAACWEGGLHVDGVALNLTFCCTPRPK
EKSNLIVVRRGCSPPTSSPVQPHAGCQLSQMTFHKIPVDSLEWHENLGHGSFTKIYRGCR
HEPVDGEPRKTEVLLKVLDAKHKNCTESFLEAASLMSQVSYQHLVLLHGVCMAGDSIMVQ
EFVHLGALDTYLRKCGHLVPASWKLQVIKQLAYALNYLEDKGLIHGNVSARKVLLAREGS
DGSLPFIKLSDPGVSPTVLSLEMLTDRIPWVAPECLQEARTLGLEADKWGFGATVWEVFS
GVTMPISTMDPAKKLQFYEERQQLPAPKWMELALLIQQCMTYEPGHRPSFRAVIRDLNNL
ITSDYELLSDPTPGALAPRDGLWNGAQFYASQDPTIFEERHLKYISQLGKGNFGSVELCR
YDPLGDNTGALVAVKQLQHSGPDQQRDFQREIQILKALHSDFIVKYRGVSYGPGRQSLRL
VMEYLPSGCLRDFLQRHRARLDASRLLLYASQICKGMEYLGSRRCVHRDLAARNILVESE
THVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSFGVVLYEL
FTYSDKSCSPSTEFLRMMGCERDVPALCRLLDLLAEGQRLPAPPACPSEVHELMKLCWAP
SPQDRPSFSTLGPQLDALWSGSRG
NT seq
3315 nt
NT seq
+upstream
nt +downstream
nt
atggcgcctccgagcgaggagacgcccctgatctctcagcgatcttgcagcctctcgtct
tcagagactggtgccttgcatgtgctgctgccccctcggggccctgggccccctcagcgc
ctctccttctcctttggggaccactcagctgaagaactgtgtgttcaggctgctaaggcc
agtggcatcctgcccgtgtaccactccctctttgctctggccgtggaagacctgtcctgc
tggtttcccccaagccacatcttctccgtggaggatgtgggcacccaggtccttgtctac
aggctccgcttttacttccctgactggtttgggctagagaagtgtcaccgattcgggctt
cgaaaggacttggccagtgccatccttgacctgccagtcctggaacacctattcgcccag
caccgccacgacctggtgagcggccgcctctccgtgggcctcagcctcaaggagcagggc
gaatgtctgagcctggctgtgctggacctggcccggatggcctgtgagcaggcccagcgg
ccagaggagctgctgaagaccatcagctacaagacctgcctgcctcccagtctgcgcgac
ctgatccagggcctgagctttgttacacggaggcgcatccggaggagggtgcgccaggcc
ctgtgccgcgtggcgacctgtcaggttgacaggcactcactcatggtcaagtacatcatg
gacctggagcgactggacccgaccagggctaccgagaccttcctcgtgggcctccccggg
gctgctggtggtcaggacgcatcggggttgctccgcgtgtctggtggtagcggcattacc
tggagtccaggaccacaggaggtcttccagcctttctgcgactttccagaaatcgtggac
atcagcatcaagcaggccccgcgcgttggcccggctggggaacaccgcctggtcaccgtc
accaggacagacaaccagatcctggaggctgagttcccggggctgccagccgcgttgtct
ttcgtggcgcttgtcgacggctacttccggctgaccaccgactctcggcactacttctgc
aaggaggtggcgcctccgcggctccttgaggaggtggcgcagcagtgccacggccccatc
accctggattttgccatcaacaaactcaagactgagggctcccttcctggctcctatgtt
ctccgtcgcagcccccaggatttcaacagcttcctcctcactgtttgtgtccagaccccc
ctgggccccgattacaagggctgcctcatccggtgcgaccccacaggaaccttttccttg
gctggccttggccgaccccacagcagtcttcgagagctactggcagcctgctgggagggc
gggctgcatgtagatggggttgcactgaacctcaccttctgttgcacccctagacccaaa
gaaaagtccaatctgattgtagtccggagaggctgcagtccacccacatcatcccctgtt
cagccccacgcgggatgccagctgagtcagatgaccttccacaagatccctgttgacagc
ctggagtggcatgagaacctgggtcatggatccttcaccaagatttaccggggctgtcgc
catgagcctgtggacggggagcctcggaagacagaggtgctgctcaaagtgttggacgca
aaacacaagaactgcacggagtcattcctggaagcggcgagcttgatgagccaagtgtca
taccagcatctcgtgttgcttcatggcgtgtgcatggccggagacagcatcatggtgcag
gaatttgtacacctgggagcattggacacatatctacgtaagtgtggccatctggtgcca
gccagctggaagctgcaggtaatcaaacagctggcctacgccctcaactatctggaggac
aaaggcctcatccatggcaatgtctcggcccgtaaggtgctcttggctcgggaggggtct
gatgggagcctgcccttcatcaagctgagtgatcctggtgtcagtcccactgtgctaagc
ctcgagatgctcactgacaggatcccctgggtggcccctgaatgtctccaggaggcccgg
acacttggcttggaagctgacaagtggggctttggtgccacagtctgggaggtgttcagc
ggtgtcacaatgccaatcagtaccatggaccctgccaagaagctccagttttatgaggaa
cggcagcagctgcctgcccccaagtggatggagctggccctactgatccaacagtgcatg
acctacgagccaggccacaggccctcctttcgtgctgtcatccgtgatctgaacaacctc
attacgtcagattacgaactcctctcagaccccacacctggtgctctggcgccccgtgat
gggctgtggaatggcgcccagttctatgccagccaggaccccaccatctttgaggagaga
cacctcaagtacatttcacagctgggcaagggcaactttggcagcgtggaactgtgccgc
tatgacccactgggagacaacacaggagccctggtggctgtgaagcagctgcagcacagc
gggccagaccagcagagggacttccagcgggagatccagatcctcaaagccctgcacagc
gactttattgtcaagtatcgtggtgtcagctatggcccaggccgccagagcctgaggctg
gtcatggaatacctacccagtggctgcctgcgggacttcctgcagcggcaccgcgcacgc
ctggatgccagccgcctgctcctctatgcctcgcagatctgcaagggcatggagtacctg
ggctcccgccgctgtgtgcaccgcgacctggcagcgcgtaacatcctggtggagagcgag
acgcacgtcaagatcgctgactttggcctcgcgaagctgctgccactggataaagattat
tacgttgtccgcgagccgggccaaagccccatcttctggtacgccccggagtccctctca
gacaacatcttctcgcgccagtcggacgtctggagctttggggtcgttctgtatgagcta
ttcacctacagtgacaagagctgcagcccttccactgagttcctgcggatgatgggatgc
gagcgagatgtgccggctctctgccgcctcctggaccttctggcagagggccagaggctg
cctgcacctccagcctgccctagtgaggttcatgagctcatgaagctgtgctgggctccc
agcccacaagaccggccatccttcagcaccctgggcccccagctggatgcactgtggagt
gggagccgggggtag
DBGET
integrated database retrieval system
