KEGG   Pteronotus mesoamericanus (Parnell's mustached bat): 129075823
Entry
129075823         CDS       T09558                                 
Symbol
CDK4
Name
(RefSeq) cyclin-dependent kinase 4
  KO
K02089  cyclin-dependent kinase 4 [EC:2.7.11.22]
Organism
ppam  Pteronotus mesoamericanus (Parnell's mustached bat)
Pathway
ppam01522  Endocrine resistance
ppam04110  Cell cycle
ppam04115  p53 signaling pathway
ppam04151  PI3K-Akt signaling pathway
ppam04218  Cellular senescence
ppam04530  Tight junction
ppam04660  T cell receptor signaling pathway
ppam04933  AGE-RAGE signaling pathway in diabetic complications
ppam04934  Cushing syndrome
ppam05160  Hepatitis C
ppam05162  Measles
ppam05163  Human cytomegalovirus infection
ppam05164  Influenza A
ppam05165  Human papillomavirus infection
ppam05166  Human T-cell leukemia virus 1 infection
ppam05167  Kaposi sarcoma-associated herpesvirus infection
ppam05169  Epstein-Barr virus infection
ppam05200  Pathways in cancer
ppam05203  Viral carcinogenesis
ppam05212  Pancreatic cancer
ppam05214  Glioma
ppam05218  Melanoma
ppam05219  Bladder cancer
ppam05220  Chronic myeloid leukemia
ppam05222  Small cell lung cancer
ppam05223  Non-small cell lung cancer
ppam05224  Breast cancer
ppam05225  Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:ppam00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    129075823 (CDK4)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    129075823 (CDK4)
   04115 p53 signaling pathway
    129075823 (CDK4)
   04218 Cellular senescence
    129075823 (CDK4)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    129075823 (CDK4)
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    129075823 (CDK4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    129075823 (CDK4)
   05203 Viral carcinogenesis
    129075823 (CDK4)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    129075823 (CDK4)
   05225 Hepatocellular carcinoma
    129075823 (CDK4)
   05214 Glioma
    129075823 (CDK4)
   05220 Chronic myeloid leukemia
    129075823 (CDK4)
   05218 Melanoma
    129075823 (CDK4)
   05219 Bladder cancer
    129075823 (CDK4)
   05224 Breast cancer
    129075823 (CDK4)
   05222 Small cell lung cancer
    129075823 (CDK4)
   05223 Non-small cell lung cancer
    129075823 (CDK4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    129075823 (CDK4)
   05160 Hepatitis C
    129075823 (CDK4)
   05164 Influenza A
    129075823 (CDK4)
   05162 Measles
    129075823 (CDK4)
   05163 Human cytomegalovirus infection
    129075823 (CDK4)
   05167 Kaposi sarcoma-associated herpesvirus infection
    129075823 (CDK4)
   05169 Epstein-Barr virus infection
    129075823 (CDK4)
   05165 Human papillomavirus infection
    129075823 (CDK4)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    129075823 (CDK4)
   04934 Cushing syndrome
    129075823 (CDK4)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    129075823 (CDK4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ppam01001]
    129075823 (CDK4)
Enzymes [BR:ppam01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.22  cyclin-dependent kinase
     129075823 (CDK4)
Protein kinases [BR:ppam01001]
 Serine/threonine kinases: CMGC group
  CDK family
   129075823 (CDK4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr APH Kdo ABC1 Haspin_kinase Kinase-like
Other DBs
NCBI-GeneID: 129075823
NCBI-ProteinID: XP_054435982
LinkDB
Position
Unknown
AA seq 303 aa
MATPRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGAGGGLPISTVREVALL
RRLEAFEHPNVVRLMDVCATARTDRETKVTLVFEHVDQDLRTYLDKAPPPGLPVETIKDL
MRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWY
RAPEVLLQSTYATPVDLWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPR
DVSLPRGAFSPRGPRPVQSMIPEMEESGAQLLLEMLTFNPHKRISAFRALQHSYLQKAEG
NPE
NT seq 912 nt   +upstreamnt  +downstreamnt
atggctactcctcgatatgagccagtggcggagattggtgttggtgcctatgggacggtg
tacaaggcccgtgatccccacagtggccactttgtggccctcaagagcgtgagagtcccc
aatggaggaggtgctggagggggccttcccatcagtacagttcgtgaggtggccttactg
aggcggctggaagcttttgagcatcccaatgttgtccggctgatggacgtctgtgccacc
gcccgcactgaccgggagaccaaagtgaccctggtgtttgagcatgtggaccaagatcta
aggacgtatctggacaaggcacccccaccaggcttgccagtggaaaccattaaggatctg
atgcgccagtttctaagaggcctggatttccttcatgccaactgcattgttcaccgggac
ctgaagccagagaacattctggtgacaagtggtgggacggtcaagctggctgactttggc
ctggccagaatctacagctaccagatggcacttacacctgtggttgttacgctctggtac
cgtgctccggaagttcttctgcagtctacgtatgcaacacctgtggacttgtggagtgtt
ggctgtatctttgcagagatgtttcgtcgaaagcctctcttctgtggaaactctgaagcg
gatcaattaggcaaaatctttgacctgattgggctgcccccagaggatgactggccccga
gatgtgtctctgccccgaggagccttttcccccagagggccccgcccagtgcagtccatg
atacctgagatggaggagtctggagcacagctgctgctggagatgctgacttttaaccca
cataagcgaatctctgccttccgagccctgcagcactcttatctacaaaaggcagaaggt
aacccagaatga

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