Phocoena phocoena (harbor porpoise): 136135469
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Entry
136135469 CDS
T11058
Symbol
ITCH
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
pphc Phocoena phocoena (harbor porpoise)
Pathway
pphc04120
Ubiquitin mediated proteolysis
pphc04144
Endocytosis
pphc04330
Notch signaling pathway
pphc04668
TNF signaling pathway
pphc04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
pphc00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
136135469 (ITCH)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
136135469 (ITCH)
04668 TNF signaling pathway
136135469 (ITCH)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
136135469 (ITCH)
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
136135469 (ITCH)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
pphc04131
]
136135469 (ITCH)
04121 Ubiquitin system [BR:
pphc04121
]
136135469 (ITCH)
Enzymes [BR:
pphc01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
136135469 (ITCH)
Membrane trafficking [BR:
pphc04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
136135469 (ITCH)
Ubiquitin system [BR:
pphc04121
]
Ubiquitin ligases (E3)
HECT type E3
136135469 (ITCH)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
136135469
NCBI-ProteinID:
XP_065749414
LinkDB
All DBs
Position
15:63343703..63414903
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AA seq
862 aa
AA seq
DB search
MSDSGSQLGSMGSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVTVDGQSKKTEKCNNT
NSPKWKQPLTVIVTPVSKLHFRVWSHQTLKSDVLLGTAALDIYETLKSNNMKLEEVVVTL
QLVGDKEPTETIGDLSVCLDGLQLESEVIANGETTCSESASQNDDGSRPKDETRASTNGS
DHPEDAGSGENRRVNGNNSPSLSNGGFKPSRPPRPSRPPPPTPRRPASVNGSPSATSESD
GSSTGSLPPTNTNSNTSEGATSGLIIPLTISGGSGPRPLNPVPQAPLPPGWEQRVDQHGR
VYYVDHIEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQWQ
LQRSQLQGAMQQFNQRFIYGNQDLFATSQNKEFDPLGPLPPGWEKRTDNNGRVYFVNHNT
RITQWEDPRNQGQLNEKPLPEGWEMRFTVDGIPYFVDHNRRTTTYIDPRTGKSALDNGPQ
IAYVRDFKAKVQYFRFWCQQLAMPQHIKITVTRKTLFEDSFQQIMSFSPQDLRRRLWVIF
PGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFI
GRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECGL
EMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGF
NEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYTRTSKQIMWFWQFVKEIDN
EKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYK
SYEQLKEKLLFAIEETEGFGQE
NT seq
2589 nt
NT seq
+upstream
nt +downstream
nt
atgtctgacagtggatcacagcttggttcaatgggtagcctgaccatgaaatcacaactt
cagataactgtcatttcagcgaaacttaaagaaaataaaaagaattggtttgggccaagt
ccttatgtggaagtcacagtagatggacagtcaaagaagacagaaaaatgcaacaatacg
aacagtcccaaatggaagcaacctcttacagttatcgtcacccctgtgagtaaattacat
tttcgtgtgtggagtcaccagacattgaaatctgatgttttgttgggaactgctgcatta
gatatctatgaaacattaaagtcaaacaatatgaaacttgaggaagtagttgtgacttta
cagcttgtaggtgacaaagaaccaacagagacaataggagatttgtcagtttgtcttgat
gggctgcagctagagtctgaagttattgctaatggtgaaactacatgttcagaaagtgct
tcacagaatgatgatggctccagacccaaggatgaaacaagagcgagcacaaatggatca
gaccatcctgaggatgcagggtctggtgaaaataggagggtcaatgggaacaattctcca
tcactctcaaatggcggttttaaaccttctaggcctccaagaccttcacgaccacctcca
cctaccccacgtagaccagcatctgtcaatggctcaccatctgccacttctgaaagtgat
ggctctagtacaggctctctcccaccaacgaatacaaattcaaatacatctgaaggagca
acatctggattaataattcctcttactatatctggaggttcaggccctaggccattaaat
cctgtacctcaagctcccctcccacccggttgggagcagagagtggaccagcatggacga
gtttactatgtagatcatattgaaaaaagaacaacgtgggatagaccagaacctctacct
cctggctgggaacggcgggttgacaacatgggacgtatttattatgttgaccatttcaca
agaacaacgacgtggcagaggccaacattggaatccgtccggaactatgaacagtggcag
ctccaacgtagtcagcttcaaggagctatgcagcagtttaaccagaggttcatttatggg
aatcaagacttgtttgctacatcacaaaataaagaatttgatcccctgggtcccctgcca
cctggatgggagaagagaacggacaacaatggtagagtatattttgtcaaccacaatact
cgtattacacaatgggaagaccccagaaatcaaggtcaattaaatgaaaagcccttacct
gaaggctgggaaatgaggttcacagtagatggaattccatattttgtggaccacaataga
agaacaaccacctatatagatccccgcactggaaaatctgccttagacaatggaccccag
atagcctatgtacgggacttcaaggcaaaggttcagtatttccggttctggtgtcagcaa
ctggccatgccacagcacataaagattacagtgacaagaaaaacattgtttgaggattcc
tttcagcagataatgagcttcagtccccaagatctgcgaagacgtttgtgggtgattttt
ccaggagaagaaggtttagattatggaggtgtagcaagagaatggttctttcttttgtca
catgaggtgttgaacccaatgtattgcctgtttgaatatgcagggaaggataattactgc
ttgcagataaaccccgcttcttacatcaatccagatcacctgaaatattttcgttttatt
ggcaggtttattgctatggctctgttccatgggaaattcatagacacaggtttttctttg
ccattctataagcgtatcttgaacaaaccagttggtctcaaggatttagaatctattgat
ccagaattttacaattctctcatctgggttaaagaaaacaatattgaggaatgtggtttg
gaaatgtatttttccgtcgataaagaaattttaggtgaaatcaagagtcatgatttgaaa
cccaatggtggcaatattcttgtaacagaagaaaataaagaggaatatatcagaatggta
gctgaatggaggttgtctcgcggtgttgaagaacagacacaagctttctttgagggcttt
aatgaaattcttccccagcagtatttgcagtactttgatgcaaaggaattagaggttctt
ttatgtggaatgcaagagattgatttgaatgactggcaaagacatgccatctaccgtcat
tacactaggacaagcaaacaaatcatgtggttttggcagtttgttaaagaaatcgataat
gagaagagaatgagacttttgcagtttgttactggaacctgccgattgccagttggcgga
tttgctgacctcatggggagcaatgggccacagaaattctgcattgaaaaagttgggaaa
gaaaattggttgcctagaagtcatacctgttttaaccgcctggacctgccaccctacaag
agctatgagcaactgaaggaaaagctgttatttgctattgaagaaacagaaggatttgga
caagagtga
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