Phocoena phocoena (harbor porpoise): 136137568 Help Entry 136137568         CDS       T11058                                  Symbol IRS2 Name (RefSeq) insulin receptor substrate 2   KO K07187   insulin receptor substrate 2 Organism pphc  Phocoena phocoena (harbor porpoise) Pathway pphc04022   cGMP-PKG signaling pathway pphc04068   FoxO signaling pathway pphc04081   Hormone signaling pphc04140   Autophagy - animal pphc04152   AMPK signaling pathway pphc04211   Longevity regulating pathway pphc04213   Longevity regulating pathway - multiple species pphc04910   Insulin signaling pathway pphc04920   Adipocytokine signaling pathway pphc04923   Regulation of lipolysis in adipocytes pphc04930   Type II diabetes mellitus pphc04931   Insulin resistance pphc04932   Non-alcoholic fatty liver disease pphc04935   Growth hormone synthesis, secretion and action pphc05010   Alzheimer disease pphc05206   MicroRNAs in cancer Brite KEGG Orthology (KO) [BR:pphc00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     136137568 (IRS2)    04022 cGMP-PKG signaling pathway     136137568 (IRS2)    04152 AMPK signaling pathway     136137568 (IRS2)   09133 Signaling molecules and interaction    04081 Hormone signaling     136137568 (IRS2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     136137568 (IRS2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     136137568 (IRS2)    04923 Regulation of lipolysis in adipocytes     136137568 (IRS2)    04920 Adipocytokine signaling pathway     136137568 (IRS2)    04935 Growth hormone synthesis, secretion and action     136137568 (IRS2)   09149 Aging    04211 Longevity regulating pathway     136137568 (IRS2)    04213 Longevity regulating pathway - multiple species     136137568 (IRS2)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     136137568 (IRS2)   09164 Neurodegenerative disease    05010 Alzheimer disease     136137568 (IRS2)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     136137568 (IRS2)    04932 Non-alcoholic fatty liver disease     136137568 (IRS2)    04931 Insulin resistance     136137568 (IRS2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  IRS PH PH_11 MEKK4_N Motif Other DBs NCBI-GeneID:  136137568 NCBI-ProteinID:  XP_065752017 LinkDB All DBs Position 18:complement(77603035..77679492) Genome browser AA seq 1439 aa AA seqDB search MASPPMNGRPGPAGGDGPNLNLNHNNNNNNSGVRKCGYLRKQKHGHKRFFVLRGPGAGGD EAAAAATAGGGPAPQPPRLEYYESEKKWRSKAGAPKRVIALDCCLNINKRADAKHKYLIA LYTKDEYFAVAAENEQEQEGWYRALTDLVSEGRAIAGDAPPAAAAAAPSASCSASLPGAL GGSAGAAVAAAADDSYGLVAPATAAYREVWQVNLKPKGLGQSKNLTGVYRLCLSARTIGF VKLNCEQPSVTLQLMNIRRCGHSDSFFFIEVGRSAVTGPGELWMQADDSVVAQNIHETIL EAMKALKELFEFRPRSKSQSSGSSATHPISVPGARRHHHLVNLPPSQTGLVRRSRTDSLA ATPPAAKCNSCRVRTASEGDGGVAAGAGDGGVAAGAGAAAGRPVSVAGSPLSPGPVRAPL SRSHTLSGGCGGRASKVTLAPAGGALQHSRSMSMPVAHSPPAAATSPGSLSSSSGHGSGS YPPPPGPHPHMQHPLHPQRPSSGSASASGSPSDPGFMSLDEYGSSPGDLRTFCSLRSNTP ESIAETPPARDGSGGDLYGYMTMDRPLSHCGRPYRRVSGDGAQDLDRGLRKRTYSLTTPA RQRPVPQPSSASLDEYTLMRATFSGSSGRLCPSCPASSPKVAYHPYPEDYGDIEIGSHRS SSSNLGTDDGYMPMTPGVALAGGGGSCKSDDYMPMSPTSVSAPKQILQPRAAVAALPPTG AAGPTPASTASRAFPGSGGGYKTSSPAESSPEDSGYMRMWCGGSKLSVESAADGRLLPNG DYLNMSPGDAGASSTPPDFFSAALHAGGGGEMLRGVPGYCYSSLPRSYKAAYTCNGDNDQ YVLMSSPVGRILEEERLESTAGPGSTQPAGAFAAGAGGGGGHPQPPHPVVPSPGRPGGNG SGRLEGFLGQRCRATRPTRLSLEGLQTLPRMHEYPLPPEPKSPGEYINIDFGEAGARLSP PAPPLLASAASSSSLLSAGSPASSLGSGTPGTSGDSRQRSPLSDYMNLDFSSPKSPQPGG QAGDPVGSLDALLSPEASAYPPLPPRPAAPSSALQLAPPPPPPGELYRLPPAPPCQGLGA ASSPSSGAGDSGDYTEMAFGVAATPPQPIAAPPKPDGARVSSPMSGLKRLSLMDQVSGVE AFLQASQPPDPHRGAKVIRADPQGGRRRHSSETFSSTTTVTPVSPSFAHNPKRHNSASVE NVSLRKSGEGGGGSVLGGGDEPPTSPRQLPPPLHPQARPWTPSQPGGLVGCPGGSGSPMR RETSAGFQNGLNYIAIDVRDEPGLSPSPQQHPQTGDKSAWGRTRSLGGLIGAVGAGSTGG VCVGPGPGALPSASTYASLDFLTHHLKEATVVKGRGELCPVQAVASSARDADRDSSSIRD LIALAGLRGEVEDGLASGPGALSGGLQLDWDACWLVPGHRELPLAAGSGDHSPLVAAGC NT seq 4320 nt NT seq  +upstreamnt  +downstreamnt atggcgagcccgccgatgaacgggcgccccgggccggcgggtggcgacggccccaacctc aacctcaaccacaacaacaacaacaacaacagcggcgtgcgcaagtgcggctacctgcgc aagcagaagcacggccacaagcgcttcttcgtgctgcgcggacccggagcgggcggcgac gaggcggcggcggcggcgacagcgggcggggggccggcgccgcagccgccgcggctcgag tactacgagagcgagaagaagtggcggagcaaagcgggcgccccgaagcgggtcatcgcg ctcgactgctgcctgaacatcaacaagcgcgccgacgccaagcacaagtacctgatcgcc ctctacaccaaggacgagtacttcgcagtggcggccgagaacgagcaggagcaggagggc tggtaccgcgcgctcaccgacctggtcagcgagggccgagcgatcgccggcgacgcgccc cccgccgccgccgccgccgccccctccgcgtcctgcagcgcctccctgcccggcgccctt ggcggctcggccggcgccgccgtcgccgccgcggccgatgacagctacgggctggtggcg cccgccacggccgcctaccgtgaggtgtggcaagtgaacctgaagcccaaaggcctgggc cagagcaagaacctgacgggcgtgtaccgcctgtgcttgtcggcgcgcaccatcggcttc gtgaagctcaactgcgagcagccgtcggtgacgctgcagctgatgaacatccgccgctgc ggccactcggacagcttcttcttcatcgaggtgggccgctcggccgtcacgggccccggt gagttgtggatgcaggcagacgactcggtggtggcgcagaacatccacgagaccatcctg gaggccatgaaggcgctcaaggagctcttcgagtttcggccgcgcagcaagagccagtcg tccggctcgtcggccacgcaccccatcagcgtccccggcgcgcgtcgccaccaccacctg gtcaacctgccccccagccagacgggcctggtgcgccgctcgcgcacggacagcttggcc gccacaccgccggccgccaagtgcaactcttgccgggtgcgcacggccagcgagggcgac ggcggcgtggcggcgggggccggcgacggcggcgtggcggcgggggccggcgcggcggcc ggcaggccggtgtcggtggcggggagccccctgagcccggggccggtgcgcgcgcccctg agccgctcgcacaccctgagcggcggctgcggcggccgcgcgagtaaggtgacgctggcg ccggcagggggcgccctgcagcacagccgctccatgtccatgcccgtggcgcactcgccc ccggcggccgccaccagccccggcagcctgtcgtccagcagcgggcacggctcgggctcc tacccgccgcccccgggcccgcacccgcacatgcagcaccccctgcacccccagcgaccc tccagcggcagcgcctcggcctcgggctcccccagcgaccctggcttcatgtccctggac gagtacggctcgagccctggggacctgagaaccttctgcagtctcaggagcaacacgccc gagtccatcgccgagacgcccccagccagggacggcagcgggggcgacctgtacgggtac atgaccatggaccgtcccctgagccactgcggccgaccctaccgcagagtctccggggat ggggcccaggacttggacagggggctgaggaagaggacctactccctgaccacgcctgcc cggcagcggccggtgccccagccctcctccgcgtccctggatgaatacaccctgatgcgg gccaccttctccggcagctcaggccgcctctgcccgtcgtgccccgcgtcctcccccaaa gtggcctaccacccctaccccgaggattacggcgacatcgagatcgggtcgcacaggagc tccagcagtaacctgggcacggacgacggctacatgcccatgacccccggcgtggccctc gcgggcggcggcgggagttgcaagagcgacgactacatgcccatgagccccaccagcgtg tccgccccgaagcagattctgcagccgcgcgccgccgtcgcggccttgccccccacggga gccgcggggcccacgcccgcgtctaccgccagcagggccttcccggggagcgggggaggc tacaagaccagctccccggccgagagctccccggaggacagcgggtacatgcgcatgtgg tgcggaggctccaagctgtccgtagagagcgccgccgacggcaggctgcttccaaacggg gactacctcaatatgtcccccggcgacgcgggagcctcgagcaccccgcccgacttcttc tcggccgccctgcacgccggcggcggcggggagatgctccggggcgtccctggctactgt tacagctccctgccgcgctcctacaaggccgcctacacctgcaacggggacaacgaccag tacgtgctcatgagctcccccgtggggcgcattctggaggaggagcggctggagtcgacg gccggcccggggtccacgcagccagccggcgccttcgcggccggggcagggggcggcggc ggccacccgcagccaccccacccggtggtgccttcgcccgggaggcccggtggcaacggc agcggccgcctggagggtttcctgggccagcgctgccgggccacgcggcccacgcgcctg tcccttgaggggctgcagaccctgccccgcatgcacgagtatcccctgccgcccgagccc aagagcccgggcgagtacatcaacatcgacttcggcgaggcgggcgcgcggctgtcgccg cccgcgcccccgctgctggcttcggccgcctcgtcgtcgtcgctgctgtccgccggcagc ccggcctcgtcgctgggctcgggcaccccgggcacaagcggcgacagccggcagcgttcc ccgctctccgactacatgaacctcgacttcagctcgcccaagtcaccccagccgggcggc caagccggggaccctgtgggctccctggacgccctcctgtcccccgaggcctccgcgtac ccgccgctgcccccgcgccccgccgccccctcctcggccctgcagctggcgcccccgccg cccccgcccggagagctgtatcgcctgcctccggcaccaccctgccagggccttggcgcg gcctcctctccatcctccggggcgggcgacagcggcgactacactgagatggccttcggc gtggctgccacgccgccgcaaccgatcgccgcgcccccgaagcccgacggggcccgcgtg agcagccccatgtccggtctgaagaggctaagcctcatggaccaggtgtcgggggtcgag gccttcctgcaagccagccagcccccagacccgcaccgcggggccaaggtcatccgcgcg gacccgcaagggggccgccgccgccacagctcggagaccttctcctcgaccaccactgtg acccccgtgtccccgtccttcgcccacaaccccaagcgccacaactcggcctcagtggag aacgtgtctctcaggaaaagtggtgaagggggcggcggcagcgtcctgggtggcggtgac gagcctcctacgtccccccgccagttgccgccgccgctccacccgcaggcgcggccctgg acgccgagccagcccgggggcttggtcggctgccccgggggcagtggctcgccgatgcgc cgggagacttctgctggcttccagaacggcctcaactacatcgccatcgacgtgagggac gagcccgggctgtcgccgtcccctcagcagcatcctcagacgggagacaagagcgcctgg ggccggacccggagcctcgggggtctcatcggcgcggtaggggccggcagcaccggcggg gtgtgtgtagggcccggccctggcgccctgccctccgccagcacctacgccagcctcgac ttcttgacgcatcacctgaaagaggccacggtcgtgaaaggtaggggtgaactgtgccca gtgcaggcggtggcttcctctgcacgggatgcggaccgagactcctcaagcatcagagac ctcatcgctctggcagggctgcgaggagaggtggaggatggtctggccagtggtccaggc gccctgagcgggggtctgcagttggactgggatgcttgctggctggtgccaggccacaga gagctgcccctggctgctgggtctggggaccacagcccgctggtggcggccggctgttag

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