Phocoena phocoena (harbor porpoise): 136139049
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Entry
136139049 CDS
T11058
Symbol
BRCA1
Name
(RefSeq) breast cancer type 1 susceptibility protein
KO
K10605
breast cancer type 1 susceptibility protein [EC:
2.3.2.27
]
Organism
pphc Phocoena phocoena (harbor porpoise)
Pathway
pphc01524
Platinum drug resistance
pphc03440
Homologous recombination
pphc03460
Fanconi anemia pathway
pphc04120
Ubiquitin mediated proteolysis
pphc04151
PI3K-Akt signaling pathway
pphc05206
MicroRNAs in cancer
pphc05224
Breast cancer
Brite
KEGG Orthology (KO) [BR:
pphc00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
136139049 (BRCA1)
09124 Replication and repair
03440 Homologous recombination
136139049 (BRCA1)
03460 Fanconi anemia pathway
136139049 (BRCA1)
09130 Environmental Information Processing
09132 Signal transduction
04151 PI3K-Akt signaling pathway
136139049 (BRCA1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
136139049 (BRCA1)
09162 Cancer: specific types
05224 Breast cancer
136139049 (BRCA1)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
136139049 (BRCA1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
pphc01009
]
136139049 (BRCA1)
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
pphc04121
]
136139049 (BRCA1)
03036 Chromosome and associated proteins [BR:
pphc03036
]
136139049 (BRCA1)
03400 DNA repair and recombination proteins [BR:
pphc03400
]
136139049 (BRCA1)
Enzymes [BR:
pphc01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.27 RING-type E3 ubiquitin transferase
136139049 (BRCA1)
Protein phosphatases and associated proteins [BR:
pphc01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
136139049 (BRCA1)
Ubiquitin system [BR:
pphc04121
]
Ubiquitin ligases (E3)
Single Ring-finger type E3
Other single Ring-finger type E3
136139049 (BRCA1)
Multi subunit type E3
BRCC complex
136139049 (BRCA1)
Chromosome and associated proteins [BR:
pphc03036
]
Eukaryotic type
Centrosome formation proteins
Centrosome duplication proteins
Regulators of centriole replication
136139049 (BRCA1)
DNA repair and recombination proteins [BR:
pphc03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
BRCA1-core complex
136139049 (BRCA1)
BRCA1-A complex
136139049 (BRCA1)
BRCA1-B complex
136139049 (BRCA1)
BRCA1-C complex
136139049 (BRCA1)
BRCA complex
136139049 (BRCA1)
FA (Fanconi anemia) pathway
Downstream FA components
136139049 (BRCA1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
BRCT
zf-C3HC4
zf-C3HC4_2
zf-RING_UBOX
zf-C3HC4_4
zf-RING_2
zf-C3HC4_3
zf-RING_5
RING_XB3-XBAT31
BRCT_2
zf-RING_6
zf-Nse
zf-ANAPC11
zf-RING_10
zf-rbx1
Prok-RING_4
zf-RING_4
Motif
Other DBs
NCBI-GeneID:
136139049
NCBI-ProteinID:
XP_065754043
LinkDB
All DBs
Position
19:18713452..18785655
Genome browser
AA seq
859 aa
AA seq
DB search
MDFSANHVEEVQNVLNAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ
CPLCKNDVTRRSLQESTRFSQLVEELLKIIHAFELDTGLQIANSYNFSKKENNSPEHLKE
EVSIIQSMGYRNRAKRLQQSEPENPTLQGTSLSVQLSNLGIVRSLRTKQQIQPQNKSVYI
ELGSDSSEDTVNKASYFSVEDHELLEITPQGAKAEASLNRAKKAACEFSEKDITKAEHHQ
FSNKDLTTTEKHETEKHPEKYQDDDERETGWEEDNRQEEQSVDSDLGEAASEYENETSLS
EDCLGLSSQSDILTTQQRDTMQDNLLKIQQEMAELEAVLEQHGSQPSHSSPSLIADSCAS
EDLLNLEQNTSEKAVLTSEKSSEYPISRNPESLSADKFQVSPDTSTSKNKEPGMERSSPS
KLQLSDNSWYMHSHSRSLQNRNCPPQKELEVVDVEEQQLTESEAQDLMEQSSLPRQDLEG
TPYLESGISLFSDDPESDPSEDRTPEPAHVCSMPPSASALKLPQFQVVESARSPATSHTT
NTAGYNVREESVSREKPELIPSTQRGNKRISMVASGLTPKEFVLVHKFARKHHITLTNLI
TEETTHVIMKTDAEFVCERTLKYFLGIAGGRWVVSYFWVTQSIKERKMLDEHDFEVRGDV
VNGRNHQGPKRARESQDRKIFKGLEICCYGPFTNMPTDQLEWMVRLCGASVVKEPSSFTL
SQGTQPIVVVQPDAWTEGGGFHVIGQMCEAPVVTREWVLDSVALYQCQELDTYLIPQPAG
PVCVYLEWGRYGNLVPSPRLQKSLVFRPPCRGSPSGAMLFLISTCLHMLYPLLRVPFLPL
PCLANSSSTLKDLAQRIGF
NT seq
2580 nt
NT seq
+upstream
nt +downstream
nt
atggatttttctgcgaatcacgttgaagaagtacaaaatgtccttaatgctatgcagaaa
atcttagagtgtccaatctgtctggagttgatcaaagagcctgtttccacaaagtgtgat
cacatattttgcaaattttgtatgctgaaacttctcaaccagaagaaagggccttcacag
tgtcctttgtgtaagaatgatgtaaccagaagaagcctacaagaaagtacaagatttagt
caacttgttgaagagctattgaagatcattcatgcttttgagcttgacacaggattgcag
attgcaaacagttataacttttcaaaaaaggaaaataactctcctgagcatctaaaggag
gaagtttctatcattcaaagtatgggctaccgaaaccgggccaaaagacttcagcagagt
gaacctgaaaatcctaccttgcagggaaccagtcttagtgtccagctctctaaccttgga
attgtgagatctctgaggacaaagcagcagatacaacctcaaaataagtccgtctacatt
gaattgggatctgattcttctgaagatacagttaataaggccagttatttcagtgtagaa
gaccatgaattgttagaaatcacccctcaaggagccaaggctgaagctagtttgaatcgt
gcaaaaaaggctgcttgtgagttttctgagaaggacataacaaaggctgaacatcatcaa
ttcagtaataaagatttgaccaccactgagaagcatgaaactgagaagcatccagaaaag
tatcaggatgatgatgaaagggaaactggctgggaagaggataatcgccaagaagagcag
agtgtggattcagacttaggtgaagcagcatccgagtatgagaatgaaacaagcctctct
gaagactgtttggggctgtcctctcagagcgatatcttaaccactcagcagagggatacc
atgcaagataacctgctaaagatccagcaggaaatggccgaactggaagctgtgttagag
cagcacgggagccagccttctcacagctccccttccctcatagccgattcttgtgcctct
gaggacctgctaaatctggagcaaaacacatcagaaaaagcagtattaacttcagagaaa
agtagtgaatatcctataagccggaatccagaaagcctttctgctgacaagtttcaagta
tctccagatacttccaccagtaaaaataaagaaccaggaatggaaaggtcttccccttct
aaattgcagttgtcagataatagttggtatatgcacagccactcaaggagtcttcagaac
agaaactgcccacctcaaaaggagcttgaggttgttgatgtggaggagcaacagctgacg
gagtctgaggcccaggatttaatggagcagtcttctttgccaagacaagatctagaggga
accccttacctagaatctggaatcagcctcttctctgatgaccctgagtctgatccctct
gaagacagaaccccagagccagctcatgtctgcagcatgccaccctcagcctctgcactg
aaattaccccaatttcaagtagtagaatctgccaggagtccggctacatctcatactact
aatactgcagggtataatgtgagggaagaaagtgtgagcagggagaagccagagttgata
ccttcaacacaaagaggcaacaaaagaatttctatggtggcatcaggcttgaccccaaaa
gaatttgtgcttgtgcacaagtttgccagaaaacatcacatcactttaactaatctaatt
actgaagagactactcatgtcattatgaaaacagatgctgagtttgtgtgtgaacggaca
ctgaaatattttctgggaattgcaggaggaagatgggtagttagctatttctgggtgacc
cagtctattaaagaaagaaagatgctggatgagcatgattttgaagtcagaggcgatgtt
gtcaatggaagaaaccatcaaggcccaaagcgagcaagagaatcccaggacaggaagatc
ttcaagggcttagaaatctgttgctatggaccatttaccaatatgcccacagatcaacta
gagtggatggtacgtctgtgtggggcttctgtggtgaaggagccctcatcattcaccctc
agccagggtactcaaccaattgtggtcgtgcagccggatgcctggacagagggcggtggc
ttccatgtcatcgggcagatgtgtgaagcacctgtggtgacccgagagtgggtattggac
agcgtagccctctaccagtgccaggagctggacacctacctgataccccagcctgcagga
ccagtctgcgtgtacctggagtggggtcgctatggcaacctggtgccctcacccagactt
cagaaaagtcttgtcttccgccctccctgccgtggcagccccagtggtgccatgctcttc
ctcatctccacgtgtttgcacatgctgtaccctctgctcagagtgcctttcctgcccctt
ccctgcctggcaaactcctcttcaaccctcaaggacctggctcagaggataggcttctga
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