Pimephales promelas (fathead minnow): 120466714
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Entry
120466714 CDS
T08155
Symbol
hsd3b1
Name
(RefSeq) hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
KO
K00070
3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:
1.1.1.145
5.3.3.1
]
Organism
pprm
Pimephales promelas (fathead minnow)
Pathway
pprm00140
Steroid hormone biosynthesis
pprm01100
Metabolic pathways
Module
pprm_M00107
Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
pprm_M00110
C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
pprm_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
pprm00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
120466714 (hsd3b1)
Enzymes [BR:
pprm01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
120466714 (hsd3b1)
5. Isomerases
5.3 Intramolecular oxidoreductases
5.3.3 Transposing C=C bonds
5.3.3.1 steroid Delta-isomerase
120466714 (hsd3b1)
BRITE hierarchy
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Ortholog
Paralog
GFIT
Motif
Pfam:
3Beta_HSD
Epimerase
NAD_binding_4
Polysacc_synt_2
GDP_Man_Dehyd
NAD_binding_10
KR
NmrA
RmlD_sub_bind
adh_short
Motif
Other DBs
NCBI-GeneID:
120466714
NCBI-ProteinID:
XP_039511232
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All DBs
Position
Unknown
AA seq
373 aa
AA seq
DB search
MALSGEVCVVTGACGFLGETLIRLLLKEKLAEIRLLDRNIRSELIQSLDDCRGETKVNVF
EGDIRDRDLLRRACKGAVLVFHTASLIDVIGAVEYSELYGVNVKGTQLLLETCIQENVAS
FIYTSSIEVAGPNGRGDPIINGDEDTPYSPSLKFSYSKTKQEAEQICLQANGELLRNGGQ
LATCALRPMYIYGPGCRFTLGHMRDGIRNGNVLLRTSRREAKVNPVYVGNAALAHLQAGR
ALRDPQKRAVMGGNFYYISDNTPPVSYSDFNYAVLSPLGFGIQERPILPFPLLYLLSFLM
ELLHVVLRPFLRFTPPLNRQLLTMLNTPFSFSYQKAHRDFGYCPHYDWEEARKRTTDWLA
SVLPTERQQINLK
NT seq
1122 nt
NT seq
+upstream
nt +downstream
nt
atggctctgtcaggagaagtgtgtgtggtgacaggagcctgcgggtttttgggagaaacc
ctgatcagactgttgctgaaagagaagctggctgagatccgactgctggatagaaacatc
cgatctgagctaatacagtctcttgatgattgcaggggggagactaaagtgaatgttttt
gagggggatatcagggaccgtgatctgctcagaagagcctgtaaaggagcagttcttgtt
tttcacacggcatctctcatcgatgtcattggagcagttgaatacagtgaattatatgga
gtcaatgttaaaggaacacaactgctgctggagacctgcatccaagaaaacgtagcctcc
ttcatttatactagcagcattgaggtggctggtcccaatggccgcggtgatccaatcatt
aacggcgatgaggacaccccctactcccccagtcttaagtttagctacagcaaaaccaag
caggaggctgaacagatttgccttcaggccaatggagagctgctccgcaatggaggccag
ctggctacttgtgcattgcggcccatgtacatctatggaccaggctgtcgatttacttta
ggccacatgagggatggaatccgcaatggaaacgtgctgctgagaacatcaagacgggag
gcaaaagtgaatcctgtatacgtgggaaacgcagccctggcacatctacaagctggtcgg
gcactcagagatcctcagaaaagggccgtaatgggtggaaatttctattacatctcagac
aacacaccacctgtcagctactctgacttcaactatgctgttctttcaccattaggcttt
gggatacaagaaaggcccattttgccctttccacttctatatcttctgtcattcctcatg
gaattactgcatgttgtgctccgacccttcctgaggttcactccacccttaaataggcag
ttactgaccatgttaaacacaccatttagtttctcatatcaaaaagctcacagggatttc
ggatattgcccacattatgactgggaagaggcacgcaagcgcactaccgattggctagca
tctgtcttacccacagagagacagcaaattaacttgaaataa
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