Pan paniscus (bonobo): 100972035
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Entry
100972035 CDS
T02283
Symbol
JAK3
Name
(RefSeq) tyrosine-protein kinase JAK3 isoform X2
KO
K11218
Janus kinase 3 [EC:
2.7.10.2
]
Organism
pps
Pan paniscus (bonobo)
Pathway
pps04062
Chemokine signaling pathway
pps04151
PI3K-Akt signaling pathway
pps04217
Necroptosis
pps04550
Signaling pathways regulating pluripotency of stem cells
pps04630
JAK-STAT signaling pathway
pps04658
Th1 and Th2 cell differentiation
pps04659
Th17 cell differentiation
pps05161
Hepatitis B
pps05162
Measles
pps05166
Human T-cell leukemia virus 1 infection
pps05169
Epstein-Barr virus infection
pps05200
Pathways in cancer
pps05203
Viral carcinogenesis
pps05223
Non-small cell lung cancer
pps05340
Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:
pps00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
100972035 (JAK3)
04151 PI3K-Akt signaling pathway
100972035 (JAK3)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
100972035 (JAK3)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
100972035 (JAK3)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
100972035 (JAK3)
04659 Th17 cell differentiation
100972035 (JAK3)
04062 Chemokine signaling pathway
100972035 (JAK3)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100972035 (JAK3)
05203 Viral carcinogenesis
100972035 (JAK3)
09162 Cancer: specific types
05223 Non-small cell lung cancer
100972035 (JAK3)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
100972035 (JAK3)
05161 Hepatitis B
100972035 (JAK3)
05162 Measles
100972035 (JAK3)
05169 Epstein-Barr virus infection
100972035 (JAK3)
09163 Immune disease
05340 Primary immunodeficiency
100972035 (JAK3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pps01001
]
100972035 (JAK3)
Enzymes [BR:
pps01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
100972035 (JAK3)
Protein kinases [BR:
pps01001
]
Non-receptor tyrosine kinases
JAK family [OT]
100972035 (JAK3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
SH2_1
FERM_F1
Jak1_Phl
Kinase-like
ABC1
Kdo
FERM_C_FAK1
SH2
LRR_RI_capping
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
100972035
NCBI-ProteinID:
XP_034800756
Ensembl:
ENSPPAG00000040942
LinkDB
All DBs
Position
20:complement(22681699..22713145)
Genome browser
AA seq
1167 aa
AA seq
DB search
MTVAQETKGPTQEGAEWDFPLAASWLCPPFEGPGSLPARQVALMAPPSEETPLIPQRSCS
LLSTEAGALHVLLPARGPGPPQRLSFSFGDHLAEDLCVQAAKASGILPVYHSLFALATED
LSCWFPPSHIFSVEDASTQVLLYRIRFYFPNWFGLEKCHRFGLRKDLASAILDLPVLEHL
FAQHRSDLVSGRLPMGLSLKEQGECLSLAVLDLARMAREQAQRPGELLKTVSYKACLPPS
LRDLIQGLSFVTRRRIRRTVRRALRRVAACQADRHSLMAKYIMDLERLDPAGAAETFHVG
LPGALGGHDGLGLLRVAGDGGIAWTQGEQEVLQPFCDFPEIVDISIKQAPRVGPAGEHRL
VTVTRTDNQILEAEFPGLPEALSFVALVDGYFRLTTDSQHFFCKEVAPPRLLEEVAEQCH
GPITLDFAINKLKTGGSHPGSYVLRRSPQDFDSFLLTVCVQTPLGPDYKGCLIRRSPTGT
FLLVGLSRPHSSLRELLATCWDGGLHVDGVAVTLTSCCIPRPKEKSNLIVVQRGHSPPTS
SLVQPQSQYQLSQMTFHKIPADSLEWHENLGHGSFTKIYRGCRHEVVDGEARKTEVLLKV
MDAKHKNCMESFLEAASLMSQVSYRHLVLLHGVCMAGDSTMVQEFVHLGAIDMYLRKRGH
LVPASWKLQVVKQLAYALNYLEDKGLPHGNVSARKVLLAREGADGSPPFIKLSDPGVSPA
VLSLEMLTDRIPWVAPECLREAQTLSLEADKWGFGATVWEVFSGVTMPISALDPAKKLQF
YEDRQQLPAPKWTELALLIQQCMAYEPVQRPSFRAVIRDLNSLISSDYELLSDPTPGALA
PRDGLWNGAQLYACQDPTIFEERHLKYISQLGKGNFGSVELCRYDPLGDNTGALVAVKQL
QHSGPDQQRDFQREIQILKALHSDFIVKYRGVSYGPGRQSLRLVMEYLPSGCLRDFLQRH
RARLDASRLLLYSSQICKGMEYLGSRRCVHRDLAARNILVESEAHVKIADFGLAKLLPLD
KDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSFGVVLYELFTYCDKSCSPSAEFLRM
MGCERDVPALCRLLELLEEGQRLPAPPACPAEVHELMKLCWAPSPQDRPSFSALGPQLDM
LWSGSRGCETHAFTAHPEGKHHSLSFS
NT seq
3504 nt
NT seq
+upstream
nt +downstream
nt
atgacagtggctcaggaaaccaaggggcccacacaggaaggagccgagtgggactttcct
ctcgctgcctcctggctctgccctcccttcgaaggtccagggtccctgcccgctaggcaa
gttgcactcatggcacctccaagtgaagagacgcccctgatccctcagcgttcatgcagc
ctcttgtccacggaggctggtgccctgcatgtgctgctgcccgctcggggccccgggccc
ccccagcgcctatctttctcctttggggaccacttggctgaggacctgtgcgtgcaggct
gccaaggccagcggcatcctgcctgtgtaccactccctctttgctctggccacggaggac
ctgtcctgctggttccccccgagccacatcttctccgtggaggatgccagcacccaagtc
ctgctctacaggattcgcttttacttccccaattggtttgggctggagaagtgccaccgc
ttcgggctacgcaaggatttggccagtgctatccttgacctgccagtcctggagcacctc
tttgcccagcaccgcagtgacctggtgagtgggcgcctccccatgggcctcagtctcaag
gagcagggtgagtgtctcagcctggccgtgttggacctggcccggatggcgcgagagcag
gcccagcggccgggagagctgctgaagactgtcagctacaaggcctgcctacccccaagc
ctgcgcgacctgatccagggcctgagcttcgtgacgcggaggcgtattcggaggacggtg
cgcagagccctgcgccgcgtggccgcctgccaggcagaccggcactcgctcatggccaag
tacatcatggacctggagcggctggatccagccggggccgccgagaccttccacgtgggc
ctccctggggcccttggtggccacgacgggctggggctgctccgcgtggctggtgacggc
ggcatcgcctggacccagggagaacaggaggtcctccagcccttctgcgactttccagaa
atcgtagacattagcatcaagcaggccccgcgcgttggcccggccggagagcaccgcctg
gtcactgttaccaggacagacaaccagattttagaggccgagttcccagggctgcccgag
gctctgtcgttcgtggcgctcgtggacggctacttccggctgaccacggactcccagcac
ttcttctgcaaggaggtggcaccgccgaggctgctggaggaagtggccgagcagtgccac
ggccccatcactctggactttgccatcaacaagctcaagactgggggctcacatcctggc
tcctatgttctccgccgcagcccccaggactttgacagcttcctcctcactgtctgtgtc
cagaccccccttggtcctgattataagggctgcctcatccggcgcagccccacaggaacc
ttccttctggttggcctcagccgaccccacagcagtcttcgagagctcctggcaacctgc
tgggatggggggctgcacgtagatggggtggcagtgaccctcacttcctgctgtatcccc
agacccaaagaaaagtccaacctgatcgtggtccagagaggtcacagcccacccacatca
tccttggttcagccccaatcccaataccagctgagtcagatgacatttcacaagatccct
gctgacagcctggagtggcatgagaacctgggccatgggtccttcaccaagatttaccgg
ggctgtcgccatgaggtggtggatggggaggcccgaaagacagaggtgctgctgaaggtg
atggatgccaagcacaagaactgcatggagtcattcctggaagcagcgagcttgatgagc
caagtgtcgtaccggcatctcgtgctgctccacggcgtgtgcatggctggagacagcacc
atggtgcaggaatttgtacacctgggggccatagacatgtatctgcgaaaacgtggccac
ctggtgccagccagctggaagctgcaggtggtcaaacagctggcctacgccctcaactat
ctggaggacaaaggcctcccccatggcaatgtctctgcccggaaggtgctcctggctcgg
gagggggctgatgggagcccgcccttcatcaagctgagtgaccctggggtcagccctgct
gtgttaagcctggagatgctcaccgacaggatcccctgggtggcccccgagtgtctccgg
gaggcccagacacttagcttggaagctgacaagtggggcttcggcgccacggtctgggaa
gtgtttagtggcgtcaccatgcccatcagcgccctggatcctgctaagaaactccaattt
tatgaggaccggcagcagctgccggcccccaagtggacagagctggccctgctgattcaa
cagtgcatggcctatgagccggtccagaggccctccttccgagccgtcattcgtgacctc
aatagcctcatctcttcagactatgagctcctctcagaccccacacctggtgccctggca
cctcgtgatgggctgtggaatggtgcccagctctatgcctgccaagaccccacgatcttc
gaggagagacacctcaagtacatctcacagctgggcaagggcaactttggcagtgtggag
ctgtgccgctatgacccgctaggcgacaatacaggtgccctggtggccgtgaaacagctg
cagcacagcgggccagaccagcagagggactttcagcgggagattcagatcctcaaagca
ctgcacagtgatttcattgtcaagtatcgtggtgtcagctatggcccgggccgccagagc
ctgcggctggtcatggagtacctgcccagcggctgcttgcgcgacttcctgcagcggcac
cgcgcgcgcctcgatgccagccgcctccttctctattcctcgcagatctgcaagggcatg
gagtacctgggctcccgccgctgcgtgcaccgcgacctggccgcccgaaacatcctcgtg
gagagcgaggcacacgtcaagatcgctgacttcggcctagctaagctgctgccgcttgac
aaagactactacgtggtccgcgagccgggccagagccccattttctggtatgcccccgaa
tccctctcggacaacatcttctctcgccagtcagacgtctggagcttcggggtcgtcctg
tacgagctcttcacctactgcgacaaaagctgcagcccctcggccgagttcctgcggatg
atgggatgtgagcgggatgtccccgccctctgccgcctcttggaactgctggaggagggc
cagaggctgccggcgcctcctgcctgccctgctgaggttcacgagctcatgaagctgtgc
tgggcccctagcccacaggaccggccatcattcagcgccctgggcccccagctggacatg
ctgtggagcggaagccgggggtgtgagactcatgccttcactgctcacccagagggcaaa
caccactccctgtccttttcatag
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