KEGG   Pan paniscus (bonobo): 100976294
Entry
100976294         CDS       T02283                                 
Symbol
CDK4
Name
(RefSeq) cyclin-dependent kinase 4 isoform X2
  KO
K02089  cyclin-dependent kinase 4 [EC:2.7.11.22]
Organism
pps  Pan paniscus (bonobo)
Pathway
pps01522  Endocrine resistance
pps04110  Cell cycle
pps04115  p53 signaling pathway
pps04151  PI3K-Akt signaling pathway
pps04218  Cellular senescence
pps04530  Tight junction
pps04660  T cell receptor signaling pathway
pps04933  AGE-RAGE signaling pathway in diabetic complications
pps04934  Cushing syndrome
pps05160  Hepatitis C
pps05162  Measles
pps05163  Human cytomegalovirus infection
pps05164  Influenza A
pps05165  Human papillomavirus infection
pps05166  Human T-cell leukemia virus 1 infection
pps05167  Kaposi sarcoma-associated herpesvirus infection
pps05169  Epstein-Barr virus infection
pps05200  Pathways in cancer
pps05203  Viral carcinogenesis
pps05212  Pancreatic cancer
pps05214  Glioma
pps05218  Melanoma
pps05219  Bladder cancer
pps05220  Chronic myeloid leukemia
pps05222  Small cell lung cancer
pps05223  Non-small cell lung cancer
pps05224  Breast cancer
pps05225  Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    100976294 (CDK4)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    100976294 (CDK4)
   04115 p53 signaling pathway
    100976294 (CDK4)
   04218 Cellular senescence
    100976294 (CDK4)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    100976294 (CDK4)
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    100976294 (CDK4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100976294 (CDK4)
   05203 Viral carcinogenesis
    100976294 (CDK4)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    100976294 (CDK4)
   05225 Hepatocellular carcinoma
    100976294 (CDK4)
   05214 Glioma
    100976294 (CDK4)
   05220 Chronic myeloid leukemia
    100976294 (CDK4)
   05218 Melanoma
    100976294 (CDK4)
   05219 Bladder cancer
    100976294 (CDK4)
   05224 Breast cancer
    100976294 (CDK4)
   05222 Small cell lung cancer
    100976294 (CDK4)
   05223 Non-small cell lung cancer
    100976294 (CDK4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100976294 (CDK4)
   05160 Hepatitis C
    100976294 (CDK4)
   05164 Influenza A
    100976294 (CDK4)
   05162 Measles
    100976294 (CDK4)
   05163 Human cytomegalovirus infection
    100976294 (CDK4)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100976294 (CDK4)
   05169 Epstein-Barr virus infection
    100976294 (CDK4)
   05165 Human papillomavirus infection
    100976294 (CDK4)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    100976294 (CDK4)
   04934 Cushing syndrome
    100976294 (CDK4)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    100976294 (CDK4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pps01001]
    100976294 (CDK4)
Enzymes [BR:pps01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.22  cyclin-dependent kinase
     100976294 (CDK4)
Protein kinases [BR:pps01001]
 Serine/threonine kinases: CMGC group
  CDK family
   100976294 (CDK4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr
Other DBs
NCBI-GeneID: 100976294
NCBI-ProteinID: XP_034791446
Ensembl: ENSPPAG00000036900
LinkDB
Position
10:36588715..36592775
AA seq 247 aa
MATSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVALL
RRLEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKVV
TLWYRAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPED
DWPRDVSLPRGAFPPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSYLH
KDEGNPE
NT seq 744 nt   +upstreamnt  +downstreamnt
atggctacctctcgatatgagccagtggctgaaattggtgtcggtgcctatgggacagtg
tacaaggcccgtgatccccacagtggccactttgtggccctcaagagtgtgagagtcccc
aatggaggaggaggtggaggaggccttcccatcagcacagttcgtgaggtggctttactg
aggcgactggaggcttttgagcatcccaatgttgtccggctgatggacgtctgtgccaca
tcccgaactgaccgggagatcaaggtaaccctggtgtttgagcatgtagaccaggaccta
aggacatatctggacaaggcacccccaccaggcttgccagccgaaaccatcaaggttgtt
acactctggtaccgagctcccgaagttcttctgcagtccacatatgcaacacctgtggac
atgtggagtgttggctgtatctttgcagagatgtttcgtcgaaagcctctcttctgtgga
aactcagaagccgaccagttgggcaaaatctttgacctgattgggctgcctccagaggat
gactggcctcgagatgtatccctgccccgtggagcctttccccccagagggccccgccca
gtgcagtcggtggtacctgagatggaggagtcgggagcacagctgctgctggaaatgctg
acttttaacccacacaagcgaatctctgcctttcgagctctgcagcactcttatctacat
aaggatgaaggtaatccggagtga

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