Pan paniscus (bonobo): 100981028
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Entry
100981028 CDS
T02283
Symbol
HSD17B4
Name
(RefSeq) peroxisomal multifunctional enzyme type 2 isoform X1
KO
K12405
(3R)-3-hydroxyacyl-CoA dehydrogenase / 3a,7a,12a-trihydroxy-5b-cholest-24-enoyl-CoA hydratase / enoyl-CoA hydratase 2 [EC:1.1.1.-
4.2.1.107
4.2.1.119
]
Organism
pps
Pan paniscus (bonobo)
Pathway
pps00120
Primary bile acid biosynthesis
pps01040
Biosynthesis of unsaturated fatty acids
pps01100
Metabolic pathways
pps01212
Fatty acid metabolism
pps04146
Peroxisome
Module
pps_M00104
Bile acid biosynthesis, cholesterol => cholate/chenodeoxycholate
pps_M00861
beta-Oxidation, peroxisome, VLCFA
pps_M00862
beta-Oxidation, peroxisome, tri/dihydroxycholestanoyl-CoA => choloyl/chenodeoxycholoyl-CoA
Brite
KEGG Orthology (KO) [BR:
pps00001
]
09100 Metabolism
09103 Lipid metabolism
00120 Primary bile acid biosynthesis
100981028 (HSD17B4)
01040 Biosynthesis of unsaturated fatty acids
100981028 (HSD17B4)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
100981028 (HSD17B4)
Enzymes [BR:
pps01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.107 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase
100981028 (HSD17B4)
4.2.1.119 enoyl-CoA hydratase 2
100981028 (HSD17B4)
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Gene cluster
GFIT
Motif
Pfam:
MFE-2_hydrat-2_N
MaoC_dehydratas
adh_short
adh_short_C2
SCP2
KR
Alkyl_sulf_C
FAS1_DH_region
AbrB-like
Motif
Other DBs
NCBI-GeneID:
100981028
NCBI-ProteinID:
XP_003826755
Ensembl:
ENSPPAG00000041825
UniProt:
A0A2R9CB89
LinkDB
All DBs
Position
4:114729320..114816784
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AA seq
809 aa
AA seq
DB search
MALGRQVLPASGVTLNYISQDSKGAARSALIFLPEIGKSLTLVPPPPFPASSCPAVGVQR
LCLFVCVSLQALFMDSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKG
VGKGSLAADKVVEEIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRS
FARISDEDWDIIHRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAA
KLGLLGLANSLAIEGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCH
DSCEENGGLFEVGAGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQS
IQESTGSIIEVLSKIDSEGGVSANHTSRATSTATSGFTGAIGQKLPPFSYAYTELEAIMY
ALGVGASIKDPKDLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHG
EQYLELYKPLPRAGKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSG
GFGGKRTSDKVKVAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFD
KPILHGLCTFGFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQ
TKVQETGDIVISNAYVDLAPTSDTSAKTPSEGEKLQSTLVFEEIGRRLKDIGPEVVKKVN
AVFEWHITKGGNIGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQK
AFFSGRLKARGNIMLSQKLQMILKDYAKL
NT seq
2430 nt
NT seq
+upstream
nt +downstream
nt
atggcccttggaaggcaagtccttccagcgagtggagtcactcttaactacatttcccag
gattccaagggagccgcgcgctctgcgctcatcttcctaccagaaattggcaagtcactg
accctcgtcccgcccccgccattccccgcctcctcctgtcccgcagtcggcgtccagcgg
ctctgcttgttcgtgtgtgtgtcgttgcaggccttattcatggactcaccgctgaggttc
gacgggcgggtggtactggtcaccggcgcgggggcaggattgggccgagcctatgccctg
gcttttgcagaaagaggagcgttagttgttgtgaatgatttgggaggggacttcaaagga
gttggtaaaggctccttagctgctgataaggttgttgaagaaataagaaggagaggtgga
aaagcagtggccaactatgattcagtggaagaaggagagaaggttgtgaagacagccctg
gatgcttttggaagaatagatgttgtggtcaacaatgctggaattctgagggatcgttcc
tttgctaggataagtgatgaagactgggatataatccacagagttcatttgcggggttca
ttccaagtgacacgggcagcatgggaacacatgaagaaacagaagtatggaaggattatt
atgacttcatcagcttcaggaatatatggcaactttggccaggccaattatagtgctgca
aagttgggtcttctgggccttgcaaattctcttgcaattgaaggcaggaaaagcaacatt
cattgtaacaccattgctcctaatgcgggatcacggatgactcagacagttatgcctgaa
gatcttgtggaagccctgaagccagagtatgtggcaccccttgtcctttggctttgtcac
gacagttgtgaggagaatggtggcttgtttgaggttggagcaggatggattggaaaatta
cgctgggagcggactcttggagctattgtaagacaaaagaatcacccaatgactcctgag
gcagtcaaggctaactggaagaagatctgtgactttgagaatgccagcaagcctcagagt
atccaagaatcaactggcagtataattgaagttctgagtaaaatagattcagaaggagga
gtttcagcaaatcatactagtcgtgcaacgtctacagcaacatcaggatttactggagct
attggccagaaactccctccattttcttatgcttatacggaactggaagctattatgtat
gcccttggagtgggagcatcaatcaaggatccaaaagatttgaaatttatttatgaagga
agttctgatttctcctgtttgcccaccttcggagttatcataggtcagaaatctatgatg
ggtggaggattagcagaaattcctggactttcaatcaactttgcaaaggttcttcatgga
gagcagtacttagagttatataaaccacttcccagagcaggaaaattaaaatgtgaagca
gttgttgctgatgtcctagataaaggatccggtgtagtgattattatggatgtctattct
tattctgagaaggaacttatatgccacaatcagttctctctctttcttgttggctctgga
ggctttggtggaaaacggacatcagacaaagtcaaggtagctgtagccatacctaataga
cctcctgatgctgtacttacagataccacctctcttaatcaggctgctttgtaccgcctc
agtggagactggaatcccttacacattgatcctaactttgctagtctagcaggttttgac
aagcccatattacatggattatgtacatttggattttctgccaggcgtgttttacagcag
tttgcagataatgatgtgtcaagattcaaggcaattaaggctcgttttgcaaaaccagta
tatccaggacaaactctacaaactgagatgtggaaggaaggaaacagaattcattttcaa
accaaggtccaagaaactggagacattgtcatttcaaatgcatatgtggatcttgcacca
acatctgatacttcagctaagacaccctctgagggcgagaagcttcagagtacccttgta
tttgaggaaataggacgccgcctaaaggatattgggcctgaggtggtgaagaaagtaaat
gctgtatttgagtggcatataaccaaaggcggaaatattggggctaagtggactattgac
ctgaaaagtggttctggaaaagtgtaccaaggccctgcaaaaggtgctgctgatacaaca
atcatactttcagatgaagatttcatggaggtggtcctgggcaagcttgaccctcagaag
gcattctttagtggcaggctgaaggccagagggaacatcatgctgagccagaaacttcag
atgattcttaaagactatgccaagctctga
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