Pan paniscus (bonobo): 100982406 Help Entry 100982406         CDS       T02283                                  Symbol IRS2 Name (RefSeq) insulin receptor substrate 2   KO K07187   insulin receptor substrate 2 Organism pps  Pan paniscus (bonobo) Pathway pps04022   cGMP-PKG signaling pathway pps04068   FoxO signaling pathway pps04081   Hormone signaling pps04140   Autophagy - animal pps04152   AMPK signaling pathway pps04211   Longevity regulating pathway pps04213   Longevity regulating pathway - multiple species pps04910   Insulin signaling pathway pps04920   Adipocytokine signaling pathway pps04923   Regulation of lipolysis in adipocytes pps04930   Type II diabetes mellitus pps04931   Insulin resistance pps04932   Non-alcoholic fatty liver disease pps04935   Growth hormone synthesis, secretion and action pps05010   Alzheimer disease pps05206   MicroRNAs in cancer Brite KEGG Orthology (KO) [BR:pps00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     100982406 (IRS2)    04022 cGMP-PKG signaling pathway     100982406 (IRS2)    04152 AMPK signaling pathway     100982406 (IRS2)   09133 Signaling molecules and interaction    04081 Hormone signaling     100982406 (IRS2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     100982406 (IRS2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     100982406 (IRS2)    04923 Regulation of lipolysis in adipocytes     100982406 (IRS2)    04920 Adipocytokine signaling pathway     100982406 (IRS2)    04935 Growth hormone synthesis, secretion and action     100982406 (IRS2)   09149 Aging    04211 Longevity regulating pathway     100982406 (IRS2)    04213 Longevity regulating pathway - multiple species     100982406 (IRS2)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     100982406 (IRS2)   09164 Neurodegenerative disease    05010 Alzheimer disease     100982406 (IRS2)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     100982406 (IRS2)    04932 Non-alcoholic fatty liver disease     100982406 (IRS2)    04931 Insulin resistance     100982406 (IRS2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  IRS PH PH_11 MEKK4_N Motif Other DBs NCBI-GeneID:  100982406 NCBI-ProteinID:  XP_034792863 LinkDB All DBs Position 14:complement(111245626..111277310) Genome browser AA seq 1340 aa AA seqDB search MASPPRQGPPGPASGDGPNLNNNNNNNNHSVRKCGYLRKQKHGHKRFFVLRGPGAGGDEA TAGGGSAPQPPRLEYYESEKKWRSKAGAPKRVIALDCCLNINKRADAKHKYLIALYTKDE YFAVAAENEQEQEGWYRALTDLVSEGRAAAGDAPPTAAPAASCSASLPGALGGSAGAAGA EDSYGLVAPATAAYREVWQVNLKPKGLGQSKNLTGVYRLCLSARTIGFVKLNCEQPSVTL QLMNIRRCGHSDSFFFIEVGRSAVTGPGELWMQADDSVVAQNIHETILEAMKALKELFEF RPRSKSQSSGSSATHPISVPGARRHHHLVNLPPSQTGLVRRSRTDSLAATPPAAKCSSCR VRTASEGDGGAAAGAAAAGARPVSVAGSPLSPGPVRAPLSRSHTLSGGCGGRGSKVALLP AGGALQHSRSMSMPVAHSPPAATSPGSLSSSSGHGSGSYPPPPGPHPPLPHPLHHGPGQR PSSGSASASGSPSDPGFMSLDEYGSSPGDLRAFCSHRSNTPESIAETPPARDGGGGGEFY GYMTMDRPLSHCGRPYRRVSGDAAQDLDRGLRKRTYSLTTPARQRPVPQPSSASLDEYTL MRATFSGSAGRLCPSCPASSPKVAYHPYPEDYGDIEIGSHRSSSSNLGADDGYMPMTPGA ALAGSGSGSCRSDDYMPMSPASVSAPKQILQPRAAAAAAVPSAGPAGPAPTSAAGRTFPA SGGGYKASSPAESSPEDSGYMRMWCGSKLSMEHADGKLLPNGDYLNVSPSDAVTTGTPPD FFSAALHPGGEPLRGVPGCCYSSLPRSYKAPYTCGGDSDQYVLMSSPVGRILEEERLEPQ AAPGPSQAASAFGAGPTQPPHPVVPSPVRPSGGLGGGRPEGFLGQRGRAVRPTRLSLEGL PSLPSMHEYPLPPEPKSPGEYINIDFGEPGARLSPPAPPLLASAASSSSLLSASSPASSL GSGTPGTSSDSRQRSPLSDYMNLDFSSPKSPKPGAPSGHPVGSLDGLLSPEASSPYPPLP PRPSASPSSSLQPPPPPPPPGELYRLPPASAVATAQGPGAASSLSSDTGDNGDYTEMAFG VAATPPQPIAAPPKPEAARVASPTSGVKRLSLMEQVSGIEAFLQASQPPDPHRGAKVIRA DPQGGRRRHSSETFSSTTTVTPVSPSFAHNPKRHNSASVENVSLRKSSEGGVGVGPGGGD EPPTSPRQLQPAPPLAPQGRPWTPGQPGGLVGCPGSGGSPMRRETSAGFQNGLNYIAIDV REEPGLPPQPQPQPPPLPQPGDKSSWGRTRSLGGLISAVGVGSTGGGCGGPGPGALPPAN TYASIDFLSHHLKEATVVKE NT seq 4023 nt NT seq  +upstreamnt  +downstreamnt atggcgagcccgccgcggcaggggccgcccgggccggcgagcggagacggccccaacctc aacaacaacaacaacaacaacaaccacagcgtgcgcaagtgcggctacctgcgcaagcag aagcacggccacaagcgcttcttcgtgctgcgcgggcccggcgcgggcggcgacgaggcg acggcgggcggggggtcggcgccgcagccgccgcggctcgagtactacgagagcgagaaa aagtggcggagcaaggcaggcgcgccgaaacgggtgatcgctctcgactgctgcctgaac atcaacaagcgcgccgacgccaagcacaagtacctgatcgccctctacaccaaggacgag tacttcgccgtggccgccgagaacgagcaggagcaggagggctggtaccgcgcgctcacc gacctggtcagcgagggccgcgcggccgccggagacgcgccccccaccgccgcgcccgcc gcgtcctgcagcgcctccctgcccggcgccctgggcggctctgccggcgccgccggggcc gaggacagctacgggctggtggctcccgccacggccgcctaccgtgaggtgtggcaggtg aacctgaagcccaagggtctgggccagagcaagaacctgacgggggtgtaccgtctgtgc ctgtcggcgcgcaccatcggcttcgtgaagctcaactgcgagcagccgtcggtgacgctg cagctcatgaacatccgccgctgcggccactcggacagcttcttcttcatcgaggtgggc cgctcggctgtcacaggccccggcgagctgtggatgcaggcggacgactcggtggtggcg cagaacatccacgagaccatcctggaggccatgaaggcgctcaaggagctcttcgagttc cggccgcgcagtaagagccaatcgtcggggtcgtcggccacgcaccccatcagcgtcccc ggcgcgcgccgccaccaccacctggtcaacctgccccccagccagacgggcctggtgcgc cgctcgcgcaccgacagcctggccgccaccccgccggcggccaagtgcagctcgtgccgg gtgcgcaccgccagcgagggcgacggcggcgcggcggcgggagcggcggccgcgggcgcc aggccggtgtcggtggctgggagccctctgagccccgggccggtgcgcgcgcccctgagc cgctcgcacaccctgagcggcggctgcggcggccgcgggagcaaggtggcgctgctgccg gcagggggcgcgctgcaacacagccgctccatgtccatgcccgtggcgcactcgccgccc gccgccaccagccccggctccctgtcgtccagcagcggccacggctcgggctcctacccg ccgccgcccggcccgcacccgcctctgccgcatccgctgcaccacggccccggccagcgg ccctccagcggcagcgcctccgcctcaggctcccccagcgaccccggcttcatgtccctg gacgagtacggctccagcccaggcgacttgcgcgctttctgcagccaccgaagcaacacg cccgagtccatcgcggagacgcccccggcccgagatggcggcggcggcggtgagttctac gggtacatgaccatggacaggcccctgagccactgtggccgcccctaccgccgggtctcg ggggacgcggcccaggacctggaccgagggctgcgcaagaggacctactccctgaccacg ccagcccggcagcggccggtgccccagccctcctctgcctcgctggatgaatacaccctg atgcgggccaccttctcgggcagcgcgggtcgcctctgcccgtcctgccccgcgtcctct cccaaggtggcctaccacccctacccagaggactacggagacatcgagatcggctcccac aggagctccagcagcaatctgggggcagacgacggctacatgcccatgacccccggcgcg gccctcgcgggcagtgggagcggcagctgcaggagcgacgactacatgcccatgagcccc gccagcgtgtccgcccccaagcagatcttgcagcccagggcagccgccgccgccgccgtg ccctctgcggggcctgcggggccagcacccacctctgcggcgggcaggacattcccggcg agtgggggcggctacaaggccagctcgcccgccgagagctcccccgaggacagtgggtac atgcgcatgtggtgcggttccaagctgtccatggagcatgcagatggcaagctgctgccc aacggggactacctcaacgtgtcccccagcgacgcggtcaccacgggcaccccgcccgac ttcttctccgcagccctgcaccccggcggggagccgctcaggggcgttcccggctgctgc tacagctccttgccccgctcctacaaggccccctacacctgcggcggggacagcgaccag tacgtgctcatgagctcccccgtggggcgcatcctggaggaggagcgtctggagcctcag gccgcgccagggcccagccaggcagccagcgccttcggggccggccccacgcagccccct caccctgtagtgccttcgcccgtgcggcctagcggcggcctaggcggcggccgcccggag ggcttcttgggccagcgcggccgggcggtgaggcccacgcgcctgtccctggaggggctg cccagcctgcccagcatgcacgagtatccactgccaccggagcccaagagccccggcgag tacatcaacatcgactttggcgagcccggggcccgcctgtcgccgcccgcgcctcccctg ctggcgtcggcggcctcgtcctcctcgctcttgtccgccagcagcccggcctcgtcgctg ggctcaggcaccccgggcaccagcagcgacagccggcagcggtctccgctctccgactac atgaacctcgacttcagctcccccaagtctcctaagccgggcgccccgagcggccacccc gtgggctccttggacggcctcctgtcccccgaggcctcctccccgtatccgccgttgccc ccgcgtccgtccgcgtccccgtcgtcgtctctgcagccgccgccaccgccgccgcccccg ggggagctgtaccgcctgccccccgcctcggccgttgccaccgcccagggcccgggcgcc gcctcatcgttgtcctcggacaccggggacaatggtgactacaccgagatggcttttggt gtggccgccaccccgccgcaacctatcgcggcccccccgaagccagaagctgcccgcgtg gccagcccgacgtcgggcgtgaagaggctgagcctcatggagcaggtgtcgggaatcgag gccttcctgcaggccagccagcccccggacccccaccgcggcgccaaggtcatccgcgca gacccgcaggggggccgccgccgccacagttccgagaccttctcctccaccacgacggtc acccccgtgtccccgtccttcgcccacaaccccaagcgccacaactcggcctccgtggaa aatgtctctctcaggaaaagcagcgagggcggcgtgggtgtcggccctggagggggcgac gagccgcccacctccccacgacagttgcagccggcgccccctttggcaccgcagggccgg ccgtggaccccgggtcagcccgggggcttggtcggttgtcctgggagcggtggatcgcca atgcgcagagagacctctgccggcttccagaatggtctcaactacatcgccatcgacgtg agggaggagcccgggctgccaccccagccgcagccgcagccgccgccgcttcctcagccg ggagacaagagctcctggggtcggacccgaagcctcgggggtctcatcagcgctgtgggc gtcggcagcaccggcggcgggtgcggggggccgggtcccggtgccctgccccctgccaac acctacgccagcattgacttcttgtcccaccacttgaaggaggccaccgtcgtgaaagag tga

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