Pan paniscus (bonobo): 100983152
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Entry
100983152 CDS
T02283
Symbol
PTEN
Name
(RefSeq) phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
KO
K01110
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:
3.1.3.16
3.1.3.48
3.1.3.67
]
Organism
pps
Pan paniscus (bonobo)
Pathway
pps00562
Inositol phosphate metabolism
pps01100
Metabolic pathways
pps01521
EGFR tyrosine kinase inhibitor resistance
pps04068
FoxO signaling pathway
pps04070
Phosphatidylinositol signaling system
pps04071
Sphingolipid signaling pathway
pps04115
p53 signaling pathway
pps04140
Autophagy - animal
pps04150
mTOR signaling pathway
pps04151
PI3K-Akt signaling pathway
pps04218
Cellular senescence
pps04510
Focal adhesion
pps04931
Insulin resistance
pps05165
Human papillomavirus infection
pps05166
Human T-cell leukemia virus 1 infection
pps05200
Pathways in cancer
pps05206
MicroRNAs in cancer
pps05208
Chemical carcinogenesis - reactive oxygen species
pps05213
Endometrial cancer
pps05214
Glioma
pps05215
Prostate cancer
pps05218
Melanoma
pps05222
Small cell lung cancer
pps05224
Breast cancer
pps05225
Hepatocellular carcinoma
pps05230
Central carbon metabolism in cancer
pps05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
pps05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
pps00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
100983152 (PTEN)
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
100983152 (PTEN)
04070 Phosphatidylinositol signaling system
100983152 (PTEN)
04071 Sphingolipid signaling pathway
100983152 (PTEN)
04151 PI3K-Akt signaling pathway
100983152 (PTEN)
04150 mTOR signaling pathway
100983152 (PTEN)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
100983152 (PTEN)
09143 Cell growth and death
04115 p53 signaling pathway
100983152 (PTEN)
04218 Cellular senescence
100983152 (PTEN)
09144 Cellular community - eukaryotes
04510 Focal adhesion
100983152 (PTEN)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100983152 (PTEN)
05206 MicroRNAs in cancer
100983152 (PTEN)
05208 Chemical carcinogenesis - reactive oxygen species
100983152 (PTEN)
05230 Central carbon metabolism in cancer
100983152 (PTEN)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
100983152 (PTEN)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
100983152 (PTEN)
05214 Glioma
100983152 (PTEN)
05218 Melanoma
100983152 (PTEN)
05215 Prostate cancer
100983152 (PTEN)
05213 Endometrial cancer
100983152 (PTEN)
05224 Breast cancer
100983152 (PTEN)
05222 Small cell lung cancer
100983152 (PTEN)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
100983152 (PTEN)
05165 Human papillomavirus infection
100983152 (PTEN)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
100983152 (PTEN)
09167 Endocrine and metabolic disease
04931 Insulin resistance
100983152 (PTEN)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100983152 (PTEN)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
pps01009
]
100983152 (PTEN)
Enzymes [BR:
pps01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.16 protein-serine/threonine phosphatase
100983152 (PTEN)
3.1.3.48 protein-tyrosine-phosphatase
100983152 (PTEN)
3.1.3.67 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase
100983152 (PTEN)
Protein phosphatases and associated proteins [BR:
pps01009
]
Protein tyrosine phosphatases (PTPs)
Class I PTPs (Dual specificity phosphatases)
Phosphatase and Tensin homologs (PTEN)
100983152 (PTEN)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PTEN_C2
Tc-R-P
PTP-SAK
DSPc
PTP-NADK
Y_phosphatase
PTPlike_phytase
Y_phosphatase3
DUF3256
Motif
Other DBs
NCBI-GeneID:
100983152
NCBI-ProteinID:
NP_001288689
Ensembl:
ENSPPAG00000029313
UniProt:
A0A024QYR5
LinkDB
All DBs
Position
8:99880836..99988640
Genome browser
AA seq
403 aa
AA seq
DB search
MTAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSK
HKNHYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVA
AIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSY
LLKNHLDYRPVALLFHKMMFETIPMFSGGTCNPQFVVCQLKVKIYSSNSGPTRREDKFMY
FEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEI
DSICSIERADNDKEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNPEAS
SSTSVTPDVSDNEPDHYRYSDTTDSDPENEPFDEDQHTQITKV
NT seq
1212 nt
NT seq
+upstream
nt +downstream
nt
atgacagccatcatcaaagagatcgttagcagaaacaaaaggagatatcaagaggatgga
ttcgacttagacttgacctatatttatccaaacattattgctatgggatttcctgcagaa
agacttgaaggcgtatacaggaacaatattgatgatgtagtaaggtttttggattcaaag
cataaaaaccattacaagatatacaatctttgtgctgaaagacattatgacactgccaaa
tttaattgcagagttgcacaatatccttttgaagaccataacccaccacagctagaactt
atcaagcccttttgtgaagatcttgaccaatggctaagtgaagatgacaatcatgttgca
gcaattcactgtaaagctggaaagggacgaactggtgtaatgatttgtgcatatttatta
catcggggcaaatttttaaaggcacaagaggccctagatttctatggggaagtaaggacc
agagacaaaaagggagtaactattcccagtcagaggcgctatgtgtattattatagctac
ctgttaaagaatcatctggattatagaccagtggcactgttgtttcacaagatgatgttt
gaaactattccaatgttcagtggcggaacttgcaatcctcagtttgtggtctgccagcta
aaggtgaagatatattcctccaattcaggacccacacgacgggaagacaagttcatgtac
tttgagttccctcagccgttacctgtgtgtggtgatatcaaagtagagttcttccacaaa
cagaacaagatgctaaaaaaggacaaaatgtttcacttttgggtaaatacattcttcata
ccaggaccagaggaaacctcagaaaaagtagaaaatggaagtctatgtgatcaagaaatc
gatagcatttgcagtatagagcgtgcagataatgacaaggaatatctagtacttacttta
acaaaaaatgatcttgacaaagcaaataaagacaaagccaaccgatacttttctccaaat
tttaaggtgaagctgtacttcacaaaaacagtagaggagccgtcaaatccagaggctagc
agttcaacttctgtaacaccagatgttagtgacaatgaacctgatcattatagatattct
gacaccactgactctgatccagagaatgaaccttttgatgaagatcagcatacacaaatt
acaaaagtctga
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