| Entry |
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| Symbol |
PTK2
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| Name |
(RefSeq) focal adhesion kinase 1 isoform X7
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| KO |
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| Organism |
pps Pan paniscus (bonobo)
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| Pathway |
| pps04670 | Leukocyte transendothelial migration |
| pps04810 | Regulation of actin cytoskeleton |
| pps04935 | Growth hormone synthesis, secretion and action |
| pps05100 | Bacterial invasion of epithelial cells |
| pps05163 | Human cytomegalovirus infection |
| pps05170 | Human immunodeficiency virus 1 infection |
| pps05202 | Transcriptional misregulation in cancer |
| pps05208 | Chemical carcinogenesis - reactive oxygen species |
| pps05418 | Fluid shear stress and atherosclerosis |
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| Brite |
KEGG Orthology (KO) [BR:pps00001]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
100989953 (PTK2)
04370 VEGF signaling pathway
100989953 (PTK2)
04151 PI3K-Akt signaling pathway
100989953 (PTK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
100989953 (PTK2)
09144 Cellular community - eukaryotes
04510 Focal adhesion
100989953 (PTK2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
100989953 (PTK2)
09150 Organismal Systems
09151 Immune system
04670 Leukocyte transendothelial migration
100989953 (PTK2)
04062 Chemokine signaling pathway
100989953 (PTK2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
100989953 (PTK2)
09158 Development and regeneration
04360 Axon guidance
100989953 (PTK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100989953 (PTK2)
05202 Transcriptional misregulation in cancer
100989953 (PTK2)
05205 Proteoglycans in cancer
100989953 (PTK2)
05208 Chemical carcinogenesis - reactive oxygen species
100989953 (PTK2)
09162 Cancer: specific types
05222 Small cell lung cancer
100989953 (PTK2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
100989953 (PTK2)
05163 Human cytomegalovirus infection
100989953 (PTK2)
05165 Human papillomavirus infection
100989953 (PTK2)
09171 Infectious disease: bacterial
05135 Yersinia infection
100989953 (PTK2)
05100 Bacterial invasion of epithelial cells
100989953 (PTK2)
09174 Infectious disease: parasitic
05146 Amoebiasis
100989953 (PTK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100989953 (PTK2)
05418 Fluid shear stress and atherosclerosis
100989953 (PTK2)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
100989953 (PTK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:pps01001]
100989953 (PTK2)
01009 Protein phosphatases and associated proteins [BR:pps01009]
100989953 (PTK2)
Enzymes [BR:pps01000]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
100989953 (PTK2)
Protein kinases [BR:pps01001]
Non-receptor tyrosine kinases
FAK family
100989953 (PTK2)
Protein phosphatases and associated proteins [BR:pps01009]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
100989953 (PTK2)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
7:complement(158052611..158397828)
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| AA seq |
1116 aa
MLLELAGQEALKPAGAIYMEKSGCSPFPVCWDKEYDRYLASSKIMAAAYLDPNLNHTPNS
STKTHLGTGMERSPGAMERVLKVFHYFESNSEPTTWASIIRHGDATDVRGIIQKIVDSHK
VKHVACYGFRLSHLRSEEVHWLHVDMGVSSVREKYELAHPPEEWKYELRIRYLPKGFLNQ
FTEDKPTLNFFYQQVKSDYMLEIADQVDQEIALKLGCLEIRRSYWEMRGNALEKKSNYEV
LEKDVGLKRFFPKSLLDSVKAKTLRKLIQQTFRQFANLNREESILKFFEILSPVYRFDKE
CFKCALGSSWIISVELAIGPEEGISYLTDKGCNPTHLADFTQVQTIQYSNSEDKDRKGML
QLKIAGAPEPLTVTAPSLTIAENMADLIDGYCRLVNGASQSFIIRPQKEGERALPSIPKL
ANSEKQGMRTHAVSVSGVSHCQHKVKKARRFLPLVFCSHDPPSTDEISGDETDDYAEIID
EEDTYTMPSKSYGIDEARDYEIQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKT
CKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRK
YSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDST
YYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRI
ENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKAQQEERMRMES
RRQATVSWDSGGSDEAPPKPSRPGYPSPRSSEGFYPSPQHMVQTNHYQVSGYPGSHGITA
MAGSIYPGQASLLDQTDSWNHRPQEIAMWQPNVEDSTVLDLRGIGQVLPTHLMEERLIRQ
QQEMEEDQRWLEKEERFLIGNQHIYQPVGKPDPAAPPKKPPRPGAPGHLGSLASLSSPAD
SYNEGVKLQPQEISPPPTANLDRSNDKVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKE
VGLALRTLLATVDETIPLLPASTHREIEMAQKLLNSDLGELINKMKLAQQYVMTSLQQEY
KKQMLTAAHALAVDAKNLLDVIDQARLKMLGQTRPH |
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| NT seq |
3351 nt +upstreamnt +downstreamnt
atgttgttggaactggcaggccaagaggccctgaaaccagcaggtgccatctatatggag
aaaagcggatgtagtccatttccagtgtgttgggataaagaatatgacagatacctagca
tctagcaaaataatggcagctgcttaccttgaccccaacttgaatcacacgccaaattcg
agtactaagactcacctgggtactggtatggaacgttctcctggtgcaatggagcgagta
ttaaaggtctttcattattttgaaagcaatagtgagccaaccacctgggccagtattatc
aggcatggagatgctactgatgtcaggggcatcattcagaagatagtggacagtcacaaa
gtaaagcatgtggcctgctatggattccgcctcagtcacctgcggtcagaggaggttcac
tggcttcacgtggatatgggcgtctccagtgtgagggagaagtatgagcttgctcaccca
ccagaggagtggaaatatgaattgagaattcgttatttgccaaaaggatttctaaaccag
tttactgaagataagccaactttgaatttcttctatcaacaggtgaagagcgattatatg
ttagagatagctgatcaagtggaccaggaaattgctttgaagttgggttgtctagaaata
cggcgatcatactgggagatgcggggcaatgcactagaaaagaagtctaactatgaagta
ttagaaaaagatgttggtttaaagcgattttttcctaagagtttactggattctgtcaag
gccaaaaccctaagaaaactgatccaacaaacatttagacaattcgccaaccttaataga
gaagaaagtattctgaaattctttgagatcctgtctccagtctacagatttgataaggaa
tgcttcaagtgtgctcttggttcaagctggattatttcagtggaactggcaatcggccca
gaagaagggatcagttacctaacggacaagggctgcaatcccacacatcttgctgacttc
actcaagtgcaaaccattcagtattcaaacagtgaagacaaggacagaaaaggaatgcta
caactaaaaatagcaggtgcacccgagcctctgacagtgacggcaccatccctaaccatt
gcggagaatatggctgacctaatagatgggtactgccggctggtgaatggagcctcgcag
tcatttatcatcagaccccagaaagaaggtgaacgggctttgccatcaataccaaagttg
gccaacagcgaaaagcaaggcatgcggacacacgccgtctctgtgtcaggagtcagtcac
tgccaacataaagttaagaaagctaggcgctttctccctttggtcttctgttcccatgat
cctccttctacggatgaaattagtggggacgaaacagatgattatgctgagattatagat
gaagaagatacttacaccatgccctcaaaaagctatggaatagatgaagccagggattat
gagattcaaagagaaagaatagaacttggacgatgtattggagaaggccaatttggagat
gtacatcaaggcatttatatgagtccagagaatccagcattggcggttgcaattaaaaca
tgtaaaaactgtacttcggacagcgtgagagagaaatttcttcaagaagccttaacaatg
cgtcagtttgaccatcctcatattgtgaagctgattggagtcatcacagagaatcctgtc
tggataatcatggagctgtgcacacttggagagctgaggtcatttttgcaagtaaggaaa
tacagtttggatctagcatctttgatcctgtatgcctatcagcttagtacagctcttgca
tatctagagagcaaaagatttgtacacagggacattgctgctcggaatgttctggtgtcc
tcaaatgattgtgtaaaattaggagactttggattatcccgatatatggaagatagtact
tactacaaagcttccaaaggaaaattgcctattaaatggatggctccagagtcaatcaat
tttcgacgttttacctcagctagtgacgtatggatgtttggtgtgtgtatgtgggagata
ctgatgcatggtgtgaagccttttcaaggagtgaagaacaatgatgtaatcggtcgaatt
gaaaatggggaaagattaccaatgcctccaaattgtcctcctaccctctacagccttatg
acgaaatgctgggcctatgaccccagcaggcggcccaggtttactgaacttaaagctcag
ctcagcacaatcctggaggaagagaaggctcagcaagaagagcgcatgaggatggagtcc
agaagacaggccacagtgtcctgggactccggagggtctgatgaagcaccgcccaagccc
agcagaccgggttatcctagtccaaggtccagcgaaggattttatcccagcccacagcac
atggtacaaaccaatcattaccaggtttctggctaccctggttcacatggaatcacagcc
atggctggcagcatctatccaggtcaggcatctcttttggaccaaacagattcatggaat
catagacctcaggagatagcaatgtggcagcccaatgtggaggactctacagtattggac
ctgcgagggattgggcaagtgttgccaacccatctgatggaagagcgtctaatccgacag
caacaggaaatggaagaagatcagcgctggctggaaaaagaggaaagatttctgattgga
aaccaacatatatatcagcctgtgggtaaaccagatcctgcagctccaccaaagaaaccg
cctcgccctggagctcccggtcatctgggaagccttgccagcctcagcagccctgctgac
agctacaacgagggtgtcaagcttcagccccaggaaatcagcccccctcctactgccaac
ctggaccggtcgaatgataaggtgtacgagaatgtgacgggcctggtgaaagctgtcatc
gagatgtccagtaaaatccagccagccccaccagaggagtatgtccctatggtgaaggaa
gtcggcttggccctgaggacgttattggccactgtggatgagaccattcccctcctacca
gccagcacccaccgagagattgagatggcacagaagctgttgaactctgacctgggtgag
ctcatcaacaagatgaaactggcccagcagtatgtcatgaccagcctccagcaagagtac
aaaaagcaaatgctgactgctgctcacgccctggctgtggatgccaaaaacttactcgat
gtcattgaccaagcaagactgaaaatgcttgggcagacgagaccacactga |
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