KEGG   Pongo pygmaeus (Bornean orangutan): 129009437
Entry
129009437         CDS       T10128                                 
Symbol
CDK4
Name
(RefSeq) cyclin-dependent kinase 4
  KO
K02089  cyclin-dependent kinase 4 [EC:2.7.11.22]
Organism
ppyg  Pongo pygmaeus (Bornean orangutan)
Pathway
ppyg01522  Endocrine resistance
ppyg04110  Cell cycle
ppyg04115  p53 signaling pathway
ppyg04151  PI3K-Akt signaling pathway
ppyg04218  Cellular senescence
ppyg04530  Tight junction
ppyg04660  T cell receptor signaling pathway
ppyg04933  AGE-RAGE signaling pathway in diabetic complications
ppyg04934  Cushing syndrome
ppyg05160  Hepatitis C
ppyg05162  Measles
ppyg05163  Human cytomegalovirus infection
ppyg05164  Influenza A
ppyg05165  Human papillomavirus infection
ppyg05166  Human T-cell leukemia virus 1 infection
ppyg05167  Kaposi sarcoma-associated herpesvirus infection
ppyg05169  Epstein-Barr virus infection
ppyg05200  Pathways in cancer
ppyg05203  Viral carcinogenesis
ppyg05212  Pancreatic cancer
ppyg05214  Glioma
ppyg05218  Melanoma
ppyg05219  Bladder cancer
ppyg05220  Chronic myeloid leukemia
ppyg05222  Small cell lung cancer
ppyg05223  Non-small cell lung cancer
ppyg05224  Breast cancer
ppyg05225  Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:ppyg00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    129009437 (CDK4)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    129009437 (CDK4)
   04115 p53 signaling pathway
    129009437 (CDK4)
   04218 Cellular senescence
    129009437 (CDK4)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    129009437 (CDK4)
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    129009437 (CDK4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    129009437 (CDK4)
   05203 Viral carcinogenesis
    129009437 (CDK4)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    129009437 (CDK4)
   05225 Hepatocellular carcinoma
    129009437 (CDK4)
   05214 Glioma
    129009437 (CDK4)
   05220 Chronic myeloid leukemia
    129009437 (CDK4)
   05218 Melanoma
    129009437 (CDK4)
   05219 Bladder cancer
    129009437 (CDK4)
   05224 Breast cancer
    129009437 (CDK4)
   05222 Small cell lung cancer
    129009437 (CDK4)
   05223 Non-small cell lung cancer
    129009437 (CDK4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    129009437 (CDK4)
   05160 Hepatitis C
    129009437 (CDK4)
   05164 Influenza A
    129009437 (CDK4)
   05162 Measles
    129009437 (CDK4)
   05163 Human cytomegalovirus infection
    129009437 (CDK4)
   05167 Kaposi sarcoma-associated herpesvirus infection
    129009437 (CDK4)
   05169 Epstein-Barr virus infection
    129009437 (CDK4)
   05165 Human papillomavirus infection
    129009437 (CDK4)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    129009437 (CDK4)
   04934 Cushing syndrome
    129009437 (CDK4)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    129009437 (CDK4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ppyg01001]
    129009437 (CDK4)
Enzymes [BR:ppyg01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.22  cyclin-dependent kinase
     129009437 (CDK4)
Protein kinases [BR:ppyg01001]
 Serine/threonine kinases: CMGC group
  CDK family
   129009437 (CDK4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr APH Kdo ABC1 Haspin_kinase Kinase-like
Other DBs
NCBI-GeneID: 129009437
NCBI-ProteinID: XP_054298312
LinkDB
Position
10:complement(55563214..55568117)
AA seq 303 aa
MATSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGAGGGLPISTVREVALL
RRLEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDL
MRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWY
RAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPR
DVSLPRGAFPPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSYLHKDEG
NPE
NT seq 912 nt   +upstreamnt  +downstreamnt
atggctacctctcgatatgagccagtggctgaaattggtgtcggtgcctatgggacagtg
tacaaggcccgtgatccccacagtggccactttgtggccctcaagagtgtgagagtcccc
aatggaggaggagctggaggaggccttcccatcagcacagttcgtgaggtggctttactg
aggcgactggaggcttttgagcatcccaatgttgtccggctgatggacgtctgtgccaca
tcccgaactgaccgggagatcaaggtaaccctggtgtttgagcatgtagaccaggaccta
aggacgtatctggacaaggcacccccaccaggcttgccagccgaaaccatcaaggatctg
atgcgccagtttctaagaggcctagatttccttcatgccaattgcatcgttcaccgagat
ctgaagccagagaacattctggtgacaagtggtggaacagtcaagctggctgactttggc
ctggccagaatctacagctaccagatggcacttacacccgtggttgttacactctggtac
cgagctcccgaagttcttctgcagtccacatatgcaacacctgtggacatgtggagtgtt
ggctgtatctttgcagagatgtttcgtcgaaagcctctcttctgtggaaactctgaagcc
gaccagttgggcaaaatctttgacctgattgggctgcctccagaggatgactggcctcga
gatgtatccctgccccgtggagcctttccccccagagggccccgcccagtgcagtcggtg
gtacctgagatggaggagtcgggagcgcagctgctgctggaaatgctgacttttaaccca
cacaagcgaatctctgcctttcgagctctgcagcactcttatctacataaggatgaaggt
aatccggagtga

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