Pongo pygmaeus (Bornean orangutan): 129009931
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Entry
129009931 CDS
T10128
Symbol
PTPN11
Name
(RefSeq) tyrosine-protein phosphatase non-receptor type 11 isoform X1
KO
K07293
tyrosine-protein phosphatase non-receptor type 11 [EC:
3.1.3.48
]
Organism
ppyg Pongo pygmaeus (Bornean orangutan)
Pathway
ppyg04014
Ras signaling pathway
ppyg04072
Phospholipase D signaling pathway
ppyg04148
Efferocytosis
ppyg04360
Axon guidance
ppyg04625
C-type lectin receptor signaling pathway
ppyg04630
JAK-STAT signaling pathway
ppyg04650
Natural killer cell mediated cytotoxicity
ppyg04660
T cell receptor signaling pathway
ppyg04670
Leukocyte transendothelial migration
ppyg04722
Neurotrophin signaling pathway
ppyg04920
Adipocytokine signaling pathway
ppyg04931
Insulin resistance
ppyg05168
Herpes simplex virus 1 infection
ppyg05205
Proteoglycans in cancer
ppyg05208
Chemical carcinogenesis - reactive oxygen species
ppyg05211
Renal cell carcinoma
ppyg05220
Chronic myeloid leukemia
ppyg05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
ppyg00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
129009931 (PTPN11)
04630 JAK-STAT signaling pathway
129009931 (PTPN11)
04072 Phospholipase D signaling pathway
129009931 (PTPN11)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
129009931 (PTPN11)
09150 Organismal Systems
09151 Immune system
04625 C-type lectin receptor signaling pathway
129009931 (PTPN11)
04650 Natural killer cell mediated cytotoxicity
129009931 (PTPN11)
04660 T cell receptor signaling pathway
129009931 (PTPN11)
04670 Leukocyte transendothelial migration
129009931 (PTPN11)
09152 Endocrine system
04920 Adipocytokine signaling pathway
129009931 (PTPN11)
09156 Nervous system
04722 Neurotrophin signaling pathway
129009931 (PTPN11)
09158 Development and regeneration
04360 Axon guidance
129009931 (PTPN11)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
129009931 (PTPN11)
05208 Chemical carcinogenesis - reactive oxygen species
129009931 (PTPN11)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
129009931 (PTPN11)
09162 Cancer: specific types
05220 Chronic myeloid leukemia
129009931 (PTPN11)
05211 Renal cell carcinoma
129009931 (PTPN11)
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
129009931 (PTPN11)
09167 Endocrine and metabolic disease
04931 Insulin resistance
129009931 (PTPN11)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
ppyg01009
]
129009931 (PTPN11)
Enzymes [BR:
ppyg01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.48 protein-tyrosine-phosphatase
129009931 (PTPN11)
Protein phosphatases and associated proteins [BR:
ppyg01009
]
Protein tyrosine phosphatases (PTPs)
Class I PTPs (Classical)
Non-receptor PTPs
129009931 (PTPN11)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Y_phosphatase
SH2
SH2_1
PTP-SAK
Tc-R-P
DSPc
Y_phosphatase3
PTPlike_phytase
PTP-NADK
Motif
Other DBs
NCBI-GeneID:
129009931
NCBI-ProteinID:
XP_054299494
LinkDB
All DBs
Position
10:111083862..111181406
Genome browser
AA seq
597 aa
AA seq
DB search
MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG
DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK
EAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYD
VGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETT
DKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEP
VSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEV
ERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQALLQGNTERTVW
QYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILI
DIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSK
RKGHEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQKSFR
NT seq
1794 nt
NT seq
+upstream
nt +downstream
nt
atgacatcgcggagatggtttcacccaaatatcactggtgtggaggcagaaaacctactg
ttgacaagaggagttgatggcagttttttggcaaggcctagtaaaagtaaccctggagac
ttcacactttccgttagaagaaatggagctgtcacccacatcaagattcagaacactggt
gattactatgacctgtatggaggggagaaatttgccactttggctgagttggtccagtat
tacatggaacatcacgggcaattaaaagagaagaatggagatgtcattgagcttaaatat
cctctgaactgtgcagatcctacctctgaaaggtggtttcatggacacctctctgggaaa
gaagcagagaaattattaactgaaaaaggaaaacatggtagttttcttgtacgagagagc
cagagccaccctggagattttgttctttctgtgcgcactggtgatgacaaaggggagagc
aatgacggcaagtctaaagtgacccatgttatgattcgctgtcaggaactgaaatacgac
gttggtggaggagaacggtttgattctttgacagatcttgtggaacattataagaagaat
cctatggtggaaacattgggtacagttctacaactgaagcagccccttaacacgactcgt
ataaatgctgctgaaatagaaagcagagttcgagaactaagcaaattagctgagaccaca
gataaagtcaaacaaggcttttgggaagaatttgagacactacaacaacaggagtgcaaa
cttctctacagccgaaaagagggtcaaaggcaagaaaacaaaaacaaaaatagatataaa
aacatcctgccctttgatcataccagggttgtcctacacgatggtgaccccaatgagcct
gtttcagattacatcaatgcaaatatcatcatgcctgaatttgaaaccaagtgcaacaat
tcaaagcccaaaaagagttacattgccacacaaggctgcctgcaaaacacggtgaacgac
ttttggcggatggtgttccaagaaaactcccgagtgattgtcatgacaacgaaagaagtg
gagagaggaaagagtaaatgtgtcaaatactggcctgatgagtatgctctaaaagaatat
ggcgtcatgcgtgttaggaacgtcaaagaaagtgccgctcatgactatacgctaagagaa
cttaaactttcaaaggttggacaagctctactccaggggaatacggagagaacggtctgg
caataccactttcggacctggccggaccacggagtgcccagcgaccccgggggcgtgctg
gacttcctggaggaggtgcaccataagcaggagagcatcatggatgcagggccggtcgtg
gtgcactgcagtgctggaattggccggacagggacgttcattgtgattgatattcttatt
gacatcatcagagagaaaggtgttgactgcgacattgatgttcccaaaaccatccagatg
gtgcggtctcagaggtcagggatggtccagacagaagcacagtaccgatttatctatatg
gcggtccagcattatattgaaacactacagcgcaggattgaagaagagcagaaaagcaag
aggaaaggtcacgaatatacaaatattaagtattctctagcggaccagacgagtggagat
cagagccccctcccgccttgtactccaacgccaccctgtgcagaaatgagagaagacagt
gctagagtctatgaaaacgtgggcctgatgcaacagcagaaaagtttcagatga
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