Pongo pygmaeus (Bornean orangutan): 129010841
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Entry
129010841 CDS
T10128
Symbol
ACACB
Name
(RefSeq) acetyl-CoA carboxylase 2 isoform X1
KO
K01946
acetyl-CoA carboxylase / biotin carboxylase 2 [EC:
6.4.1.2
6.3.4.14
2.1.3.15
]
Organism
ppyg Pongo pygmaeus (Bornean orangutan)
Pathway
ppyg00061
Fatty acid biosynthesis
ppyg00620
Pyruvate metabolism
ppyg00640
Propanoate metabolism
ppyg01100
Metabolic pathways
ppyg04152
AMPK signaling pathway
ppyg04910
Insulin signaling pathway
ppyg04920
Adipocytokine signaling pathway
ppyg04922
Glucagon signaling pathway
ppyg04931
Insulin resistance
ppyg04936
Alcoholic liver disease
Brite
KEGG Orthology (KO) [BR:
ppyg00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
129010841 (ACACB)
00640 Propanoate metabolism
129010841 (ACACB)
09103 Lipid metabolism
00061 Fatty acid biosynthesis
129010841 (ACACB)
09110 Biosynthesis of other secondary metabolites
00254 Aflatoxin biosynthesis
129010841 (ACACB)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
129010841 (ACACB)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
129010841 (ACACB)
04922 Glucagon signaling pathway
129010841 (ACACB)
04920 Adipocytokine signaling pathway
129010841 (ACACB)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
129010841 (ACACB)
04931 Insulin resistance
129010841 (ACACB)
Enzymes [BR:
ppyg01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.3 Carboxy- and carbamoyltransferases
2.1.3.15 acetyl-CoA carboxytransferase
129010841 (ACACB)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.14 biotin carboxylase
129010841 (ACACB)
6.4 Forming carbon-carbon bonds
6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
6.4.1.2 acetyl-CoA carboxylase
129010841 (ACACB)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ACC_central
Carboxyl_trans
CPSase_L_D2
ACCA_BT
Biotin_carb_N
Biotin_carb_C
Biotin_lipoyl
ATP-grasp
Dala_Dala_lig_C
ATP-grasp_3
Motif
Other DBs
NCBI-GeneID:
129010841
NCBI-ProteinID:
XP_054301347
LinkDB
All DBs
Position
10:107696418..107852054
Genome browser
AA seq
2458 aa
AA seq
DB search
MVLLLCLSCLIFSCLTFSWLKIWGKMTDSKPITKSKSEANFIPSQEPFPASDNSGETPQR
NGEGHSLPNTPSQAEPASHKGPKDAGRRRNSLPPSHQKPPRNPLSSSDAAPSPELQANGT
GTQGLEAPDTDGLSSSARPQGQQAGSPSKEDKKQANIKRQLMTNFILGSFDDYSSDEDSV
ASSSRESTRKGSRASLGALSLEAYLTTGEAETRVPTMRPSMSGLHLVKRGREHKKLDLHR
DFTVASPAEFVTRFGGDRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVT
PEDLKANAEYIKMADHYVPVPGGPNNNNYANVELIVDVAKRIPVQAVWAGWGHASENPKL
PELLCKNGVAFLGPPSEAMWALGDKIASTIVAQTLQVPTLPWSGSGLTVEWTEDDLQQGK
RISVPEDVYDKGCVKDVDEGLEAAERIGFPLMIKASEGGGGKGIRKAESAEDFPILFRQV
QSEIPGSPIFLMKLAQHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIVEEAPATIAP
LAIFEFMEQCAVRLAKTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNL
PAAQLQIAMGVPLHRLKDIRLLYGESPWGVTPISFETPSIPPLARGHVIATRITSENPDE
GFKPSSGTVQELNFRSSKNVWGYFSVAATGGLHEFADSQFGHCFSWGENREEAISNMVVA
LKELSIRGDFRTTVEYLINLLETESFQNNDIDTGWLDYLIAEKVQAEKPDIMLGVVCGAL
NVADARFRTCMTDFLHSLERGQVLPADSLLNLVDVELIYGGVKYILKVARQSLTMFVLIM
NGCHIEIDAHRLNDGGLLLSYNGNSYTTYMKEEVDSYRITIGNKTCVFEKENDPTVLRSP
SAGKLTQYTVEDGGHVEAGSSYAEMEVMKMIMTLNVQESGRVKYIKRPGAVLEAGCVVAR
LELDDPSKVHPAEPFTGELPAQQTLPILGEKLHQVFHSVLENLTNVMSGFCLPEPIFSIK
LKEWVQKLMMTLRHPSLPLLELQEIMTSVAGRIPAPVEKSVRRVMAQYASNITSVLCQFP
SQQIATILDCHAATLQRKADREVFFINTQSIVQLVQRYRSGIRGYMKTVVLDLLRRYLRV
EHHFQQAHYDKCVINLREQFKPDMSQVLDCIFSHAQVAKKNQLVIMLIDELCGPDPSLSD
ELTSILNELTQLSKSEHCKVALRARQILIASHLPSYELRHNQVESIFLSAIDMYGHQFCP
ENLKKLILSETTIFDVLPTFFYHANKVVCMASLEVYVRRGYIAYELNSLQHRQLPDGTCV
VEFQFMLPSSHPNRMTVPISITNPDLLRHSTELFMDSGFSPLCQRMGAMVAFRRFEDFTR
NFDEVISCFANVPKDTPLFSEARTSLYSEDDCKSLREEPIHILNVSIQCADHLEDEALVP
ILRTFVQSKKNILVDYGLRRITFLIAQEKEFPKFFTFRARDEFAEDRIYRHLEPALAFQL
ELNRMRNFDLTAVPCANHKMHLYLGAAKVKEGVEVTDHRFFIRAIIRHSDLITKEASFEY
LQNEGERLLLEAMDELEVAFNNTSVRTDCNHIFLNFVPTVIMDPFKIEESVRYMVMRYGS
RLWKLRVLQAEVKINIRQTTTGSAVPIRLFITNESGYYLDISLYKEVTDSRSGNIMFHSF
GNKQGPQHGMLINTPYVTKDLLQAKRFQAQSLGTTYIYDFPEMFRQALFKLWSSPDKYPK
DILTYTELVLDSQGQLVEMNRLPGGNEVGMVAFKMRFKTQEYPEGRDVIVIGNDITFRIG
SFGPGEDLLYLRASEMARAEGIPKIYVAANSGARIGMAEEIKHMFHVAWVDPEDPHKGFK
YLYLTPQDYTRISSLNSVHCKHIEEGGESRYMITDIIGKDDGLGVENLRGSGMIAGESSL
AYEEIVTISLVTCRAIGIGAYLVRLGQRVIQVENSHIILTGASALNKVLGREVYTSNNQL
GGVQIMHYNGVSHITVPDDFEGVYTILEWLSYMPKDNHSPVPIITPTDPIDREIEFLPSR
APYDPRWMLAGRPHPTLKGTWQSGFFDHGSFKEIMAPWAQTVVTGRARLGGIPVGVIAVE
TRTVEVAVPADPANLDSEAKIIQQAGQVWFPDSAYKTAQAIKDFNREKLPLMIFANWRGF
SGGMKDMYDQVLKFGAYIVDGLRQYKQPILIYIPPYAELRGGSWVVIDATINPLCIEMYA
DKESRGGVLEPEGTVEIKFRKKDLIKSMRRLDPAYKKLMEQLGEPDLSDKDRKDLEGRLK
AREDLLLPIYHQVAVQFADFHDTPGRMLEKGVISDILEWKTARTFLYWRLRRLLLEDQVK
QEILQASGELSHVHIQSMLRRWFVETEGAVKAYLWDNNQVVVQWLEQHWQAGDGPRSTIR
ENITYLKHDSVLKTIRGLVEENPEVAVDCVIYLSQHISPAERAQVVHLLSTMDSPAST
NT seq
7377 nt
NT seq
+upstream
nt +downstream
nt
atggtcttgcttctttgtctatcttgtctgattttctcctgtctgaccttttcctggtta
aaaatctgggggaaaatgacggactccaagccgatcaccaagagtaaatcagaagcaaac
ttcatcccgagccaggagccctttccagcctctgataactcaggggagacaccacagaga
aatggggagggccactctctgcccaacacccccagccaggccgagccagcctcccacaaa
ggccccaaagatgccggtcggcggagaaactccctaccaccctcccaccagaagccccca
agaaaccccctttcttccagtgacgcagcaccctccccagaacttcaagccaatgggact
gggacacaaggtctggaggccccagataccgatggcctgtcctcctcagccaggccccag
ggccagcaagctggctccccctccaaagaagacaagaagcaggcaaacatcaagaggcag
ctgatgaccaacttcatcctgggctcttttgatgactactcctccgacgaggactctgtt
gccagctcatctcgtgagtctacccggaagggcagccgggccagcttgggggccctgtcc
ctggaggcttatctgaccacaggtgaagctgagacccgcgtccccactatgaggccgagc
atgtcgggactccacctggtgaagaggggacgggaacacaagaagctggacctgcacaga
gactttaccgtggcttctcccgctgagtttgtcacacgctttgggggggatcgggtcatc
gagaaggtgcttattgccaacaatgggatcgccgccgtgaagtgcatgcgctccatccgc
aggtgggcctatgagatgttccgcaatgagcgggccatccggtttgttgtgatggtgacc
cccgaggaccttaaggccaacgcagagtacatcaagatggcagatcattacgtccccgtc
ccaggagggcccaataacaacaactatgccaacgtggagctgattgtggatgttgccaag
agaatccccgtgcaggcggtgtgggctggctggggccatgcttcagaaaaccctaaactt
ccggagctgctgtgcaagaatggagttgctttcttaggccctcccagcgaggccatgtgg
gccttaggagataagatcgcctccaccattgtcgcccagacgctacaggtcccaaccctg
ccctggagtggaagcggcctgacagtggagtggacagaagatgatctgcagcagggaaaa
agaatcagtgtcccagaagatgtttatgacaagggttgtgtgaaagacgtagatgagggc
ttggaggcagcagaaagaattggttttccattgatgatcaaagcttctgaaggtggcgga
gggaagggaatccggaaggctgagagtgcggaggacttcccgatccttttcagacaagta
cagagtgagatcccaggctcgcccatctttctcatgaagctggcccagcacgcccgtcac
ctggaagttcagatcctcgctgaccagtatgggaatgctgtgtctctgtttggtcgcgac
tgctccatccagcggcggcatcagaagatcgttgaggaagcaccggccaccatcgccccg
ctggccatattcgagttcatggagcagtgtgccgtccgcctggccaagaccgtgggctat
gtgagtgcagggacagtggaatacctctatagccaggacggcagcttccacttcttggag
ctgaatcctcgcttgcaggtggaacatccctgcacagaaatgattgctgacgtcaatctg
ccggccgcccagctacagatcgccatgggcgtgccactgcaccggctgaaggatatccgg
cttctgtacggagagtcaccatggggagtgactcccatttcttttgaaaccccctcaatc
cctcccctcgcccgaggccacgtcattgccaccagaatcaccagcgaaaacccagatgag
ggttttaagccgagctccggcactgtccaggaactgaatttccggagcagcaagaacgtg
tggggttacttcagcgtggccgctactggaggcctgcacgagtttgcggattcccagttt
gggcactgcttctcctggggagagaaccgggaagaggccatttcgaacatggtggtggct
ttgaaggaactgtccatccgaggcgactttaggactaccgtggaatacctcattaacctc
ctggagaccgagagcttccagaacaacgacattgacaccgggtggttggactacctcatt
gctgagaaagtgcaggcggagaaaccagatatcatgcttggggtggtatgcggggccttg
aacgtggccgatgcgaggttcagaacgtgcatgacagatttcttacactccctggaaagg
ggccaggtcctcccagcggattcgctactgaacctcgtagatgtggaattaatttacgga
ggtgttaagtatattctcaaggtggcccggcagtctctgaccatgtttgttctcatcatg
aatggctgccacatcgagattgacgcccaccggctgaatgatggagggctcctgctctcc
tacaatgggaacagctacaccacctacatgaaggaagaggttgacagttaccgaattacc
atcggcaataagacgtgtgtgtttgagaaggagaacgatcctacggtcctgagatccccc
tcagctgggaagctgacacagtacacagtggaggatgggggccacgttgaggctgggagc
agctacgctgagatggaggtgatgaagatgatcatgaccctgaacgtgcaggaaagtggc
cgggtgaagtacatcaagcgtccaggtgctgtgctggaagcaggctgcgtggtggccagg
ctggagcttgatgacccttctaaagtccacccggctgaaccgttcacaggagaactccct
gcccagcagacactgcccatcctcggagaaaaactgcaccaggtcttccacagcgtcctg
gaaaacctcaccaacgtcatgagtggcttttgtctgccagagcccatttttagcataaag
ctgaaggagtgggtgcagaagctcatgatgaccctccggcacccgtcactgccgctgctg
gagctgcaggagatcatgactagcgtggcaggccgcatccctgcccccgtggagaagtcg
gtccgcagagtgatggcccagtatgccagcaacatcacctcggtgctgtgccagttcccc
agccagcagatagccaccatcctggactgccacgcagccaccctgcagcggaaggccgat
cgagaggtcttcttcatcaacacccagagcatcgtgcagttggtccagagataccgcagc
gggatccgcggctatatgaaaacagtggtgttggatctcctgagaagatacttgcgtgtt
gagcaccattttcagcaagcccactacgacaagtgtgtgataaacctcagggagcagttc
aagccagacatgtcccaggtgttggactgcatcttctcccacgcgcaggtggccaagaag
aaccagttggtgatcatgttgatcgatgagctgtgtggcccagacccttccctgtcggac
gagctgacctccatcctcaacgagctcactcagctgagcaaaagcgagcactgcaaagtg
gccctcagagcccggcagatcctgattgcctcccatctcccctcctacgagctgcggcat
aaccaggtggagtccattttcctgtctgccattgacatgtacggccaccagttctgcccc
gagaacctcaagaaattaatactttcggaaacaaccatctttgacgtcctgcctactttc
ttctatcatgctaacaaagtcgtgtgcatggcgtccttggaggtttacgtgcggaggggc
tacatcgcctatgagttaaacagcctgcagcaccggcagctcccggacggtacctgtgtg
gtagaattccagttcatgctgccctcctcccacccaaaccggatgactgtgcccatcagt
atcaccaaccctgacctgctgaggcacagcacagagctcttcatggacagcggcttctcc
ccactgtgccagcgcatgggagccatggtagccttcaggagattcgaggacttcaccaga
aattttgatgaagtcatctcttgctttgccaacgtgcccaaagacacccccctcttcagc
gaggcccgcacctccctgtactccgaggatgactgcaagagcctcagagaagagcccatc
cacattctgaatgtgtccatccagtgtgcagaccacctggaggatgaggcactggtgccg
attttacggacgtttgtacagtccaagaaaaatatccttgtggattatggactccgacga
atcacattcttgattgcccaagagaaagaatttcccaagtttttcacattcagagcaaga
gatgagtttgcagaagatcgcatttaccgtcacttggaacctgccctggccttccagctg
gaactcaaccggatgcgtaacttcgatctgaccgccgtgccctgtgccaaccacaagatg
cacctttacctgggtgctgccaaggtgaaggaaggggtggaagtgacggaccataggttc
ttcatccgcgccatcatcaggcactccgacctgattacaaaggaagcctccttcgaatac
ctgcagaacgagggtgagcggctgctcctggaggccatggacgagctggaggtggcgttc
aataacaccagcgtgcgaaccgactgcaaccacatcttcctcaacttcgtgcccactgtc
atcatggaccccttcaagatcgaggagtccgtgcgctacatggttatgcgctacggcagc
cggttgtggaaactccgcgtgctgcaggctgaggtcaagatcaacatccgccagaccacc
accggcagtgccgttcccatccgcctgttcatcaccaatgagtcgggctactacctggac
atcagcctctacaaagaagtgactgactccagatccggaaatatcatgtttcactccttc
ggcaacaagcaagggccccagcacgggatgctgatcaatactccctacgtcaccaaggat
ctgctccaggccaagcgattccaggcccagtccctgggaaccacctacatctatgacttc
ccggaaatgttcaggcaggctctctttaaactgtggagctccccagacaagtatcccaaa
gacatcctgacatacactgaattagtgttggactctcagggccagctggtggagatgaac
cgacttcctggtggaaatgaggtgggcatggtggccttcaaaatgaggtttaagacccag
gagtacccggaaggacgggacgtgatcgtcatcggcaacgacatcacctttcgcattgga
tcttttggccctggggaggaccttctgtacctgcgggcatccgagatggcccgggcagag
ggcattcccaaaatctacgtggcagccaacagtggcgcccgtattggcatggcagaggag
atcaaacacatgttccacgtggcttgggtggacccagaagacccccacaaaggatttaaa
tacctgtacctgactccccaagactacaccagaatcagctccctgaactccgtccactgt
aaacacatcgaggaaggaggagaatccagatacatgatcacggatatcatcgggaaggat
gatggcttgggcgtggagaatctgaggggctcaggcatgattgctggggagtcctctctg
gcttacgaagagatcgtcaccattagcttggtgacctgccgagccattgggattggggcc
tacttggtgaggctgggccagcgagtgatccaggtggagaactcccacatcatccttaca
ggagcaagtgctctcaacaaggtcctgggaagagaggtctacacatccaacaaccagctg
ggtggcgttcagatcatgcattacaatggtgtctcccacatcaccgtgccagatgacttt
gagggggtttataccatcctggagtggctgtcctatatgccaaaggataatcacagccct
gtccctatcatcacaccaactgaccccattgacagagaaattgaattcctcccatccaga
gctccctacgacccccggtggatgcttgcaggaaggcctcacccaactctgaagggaacg
tggcagagcggattctttgaccacggcagtttcaaggaaatcatggcaccctgggcacag
accgtggtaacaggacgagcaaggcttggggggattcccgtgggagtgattgctgtggag
acacggactgtggaggtggcagtccctgcagaccctgccaacctggattctgaggccaag
ataattcagcaggcaggacaggtgtggttcccagactcagcctacaaaaccgcccaggcc
atcaaggacttcaaccgggagaagttgcccctgatgatctttgccaactggagggggttc
tctggtggcatgaaagacatgtatgaccaggtgctgaagtttggagcctacatcgtggac
ggccttagacaatacaaacagcccatcctgatctatatcccaccctacgcggagctccgg
ggaggctcctgggtggtcatagacgccaccatcaacccgctgtgcatagaaatgtatgcg
gacaaagagagcagggggggtgttctggaaccagaggggacagtggagattaagttccga
aagaaagatctgataaagtcaatgagaaggctcgatccagcttacaagaagctcatggaa
cagctaggggaacctgatctctccgacaaggaccgcaaggacctggagggccggctgaaa
gctcgcgaggacctgctgctccccatctaccaccaggtggcggtgcagttcgccgacttc
cacgacacgcccggccggatgctggagaagggcgtcatatctgacatcctggagtggaag
accgcacgcaccttcctatattggcgtctgcgccgcctcctcctggaggaccaggtcaag
caggagatcctgcaggccagtggggagctgagtcacgtgcatatccagtccatgctgcgc
cgctggttcgtggagacggagggggctgtcaaggcctacttgtgggacaacaaccaggtg
gttgtgcagtggctggaacagcactggcaggcgggggatggcccgcgctccaccatccgt
gagaacatcacgtacctgaagcacgactctgtcctcaagaccatccgaggcctggttgaa
gaaaaccccgaggtggccgtggactgtgtgatatacctgagccagcacatcagcccagct
gagcgggcgcaggtcgttcacctgctgtctaccatggacagcccggcctccacctga
DBGET
integrated database retrieval system
