KEGG   Pongo pygmaeus (Bornean orangutan): 129018687
Entry
129018687         CDS       T10128                                 
Symbol
BCL2
Name
(RefSeq) apoptosis regulator Bcl-2
  KO
K02161  apoptosis regulator Bcl-2
Organism
ppyg  Pongo pygmaeus (Bornean orangutan)
Pathway
ppyg01521  EGFR tyrosine kinase inhibitor resistance
ppyg01522  Endocrine resistance
ppyg01524  Platinum drug resistance
ppyg04064  NF-kappa B signaling pathway
ppyg04066  HIF-1 signaling pathway
ppyg04071  Sphingolipid signaling pathway
ppyg04115  p53 signaling pathway
ppyg04140  Autophagy - animal
ppyg04141  Protein processing in endoplasmic reticulum
ppyg04151  PI3K-Akt signaling pathway
ppyg04210  Apoptosis
ppyg04215  Apoptosis - multiple species
ppyg04217  Necroptosis
ppyg04261  Adrenergic signaling in cardiomyocytes
ppyg04340  Hedgehog signaling pathway
ppyg04510  Focal adhesion
ppyg04621  NOD-like receptor signaling pathway
ppyg04630  JAK-STAT signaling pathway
ppyg04722  Neurotrophin signaling pathway
ppyg04725  Cholinergic synapse
ppyg04915  Estrogen signaling pathway
ppyg04928  Parathyroid hormone synthesis, secretion and action
ppyg04933  AGE-RAGE signaling pathway in diabetic complications
ppyg05014  Amyotrophic lateral sclerosis
ppyg05022  Pathways of neurodegeneration - multiple diseases
ppyg05132  Salmonella infection
ppyg05145  Toxoplasmosis
ppyg05152  Tuberculosis
ppyg05161  Hepatitis B
ppyg05162  Measles
ppyg05168  Herpes simplex virus 1 infection
ppyg05169  Epstein-Barr virus infection
ppyg05170  Human immunodeficiency virus 1 infection
ppyg05200  Pathways in cancer
ppyg05206  MicroRNAs in cancer
ppyg05207  Chemical carcinogenesis - receptor activation
ppyg05210  Colorectal cancer
ppyg05215  Prostate cancer
ppyg05222  Small cell lung cancer
ppyg05226  Gastric cancer
ppyg05417  Lipid and atherosclerosis
ppyg05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ppyg00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    129018687 (BCL2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04340 Hedgehog signaling pathway
    129018687 (BCL2)
   04630 JAK-STAT signaling pathway
    129018687 (BCL2)
   04064 NF-kappa B signaling pathway
    129018687 (BCL2)
   04066 HIF-1 signaling pathway
    129018687 (BCL2)
   04071 Sphingolipid signaling pathway
    129018687 (BCL2)
   04151 PI3K-Akt signaling pathway
    129018687 (BCL2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    129018687 (BCL2)
  09143 Cell growth and death
   04210 Apoptosis
    129018687 (BCL2)
   04215 Apoptosis - multiple species
    129018687 (BCL2)
   04217 Necroptosis
    129018687 (BCL2)
   04115 p53 signaling pathway
    129018687 (BCL2)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    129018687 (BCL2)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    129018687 (BCL2)
  09152 Endocrine system
   04915 Estrogen signaling pathway
    129018687 (BCL2)
   04928 Parathyroid hormone synthesis, secretion and action
    129018687 (BCL2)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    129018687 (BCL2)
  09156 Nervous system
   04725 Cholinergic synapse
    129018687 (BCL2)
   04722 Neurotrophin signaling pathway
    129018687 (BCL2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    129018687 (BCL2)
   05206 MicroRNAs in cancer
    129018687 (BCL2)
   05207 Chemical carcinogenesis - receptor activation
    129018687 (BCL2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    129018687 (BCL2)
   05226 Gastric cancer
    129018687 (BCL2)
   05215 Prostate cancer
    129018687 (BCL2)
   05222 Small cell lung cancer
    129018687 (BCL2)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    129018687 (BCL2)
   05161 Hepatitis B
    129018687 (BCL2)
   05162 Measles
    129018687 (BCL2)
   05168 Herpes simplex virus 1 infection
    129018687 (BCL2)
   05169 Epstein-Barr virus infection
    129018687 (BCL2)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    129018687 (BCL2)
   05152 Tuberculosis
    129018687 (BCL2)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    129018687 (BCL2)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    129018687 (BCL2)
   05022 Pathways of neurodegeneration - multiple diseases
    129018687 (BCL2)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    129018687 (BCL2)
   05418 Fluid shear stress and atherosclerosis
    129018687 (BCL2)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    129018687 (BCL2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    129018687 (BCL2)
   01524 Platinum drug resistance
    129018687 (BCL2)
   01522 Endocrine resistance
    129018687 (BCL2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:ppyg01009]
    129018687 (BCL2)
Protein phosphatases and associated proteins [BR:ppyg01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     129018687 (BCL2)
SSDB
Motif
Pfam: Bcl-2 BH4 Bcl-2_3 ARMH5
Other DBs
NCBI-GeneID: 129018687
NCBI-ProteinID: XP_054316366
LinkDB
Position
17:complement(78051140..78250626)
AA seq 239 aa
MAHAGTTGYDNREIVMKYIHYKLSQRGYEWDAGDVGAAPPGAATAPGIFSSQPGHTPHPA
ASRDPVARTSPLPTPAAPGAAVGPALSPAPPVVHLTLRQAGDDFSRRYRRDFAEMSSQLH
LTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEY
LNRHLHTWIQDNGGWDAFVELYGPSMRPLFDFSWLSLKTLLSLALVGACITLGAYLGHK
NT seq 720 nt   +upstreamnt  +downstreamnt
atggcgcacgctgggacaacagggtacgataaccgggagatagtgatgaagtacatccat
tataagttgtcgcagaggggctacgagtgggatgcgggagatgtgggcgccgcgcccccg
ggggccgccaccgcacccggcatcttctcctcccagcccgggcacacgcctcatccagcc
gcatcccgggacccggtcgccaggacctcgccgctgccgaccccggctgcccctggcgcc
gccgtggggcctgcgctcagcccggcgccacctgtggtccacctgaccctccgccaggcc
ggcgacgacttctcccgccgctaccgccgcgacttcgccgagatgtccagccagctgcac
ctgacgcccttcaccgcgcggggacgctttgccacggtggtggaggagctcttcagggac
ggggtgaactgggggaggattgtggccttctttgagttcggtggggtcatgtgtgtggag
agcgtcaaccgggagatgtcgcccctggtggacaacatcgccctgtggatgactgagtac
ctgaaccggcacctgcacacctggatccaggataacggaggctgggatgcctttgtggaa
ctgtacggccccagcatgcggcctctgtttgatttctcctggctgtctctgaagactctg
ctcagtttggccctggtgggagcttgcatcaccctgggtgcctatctgggccacaagtga

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