Pongo pygmaeus (Bornean orangutan): 129020410
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Entry
129020410 CDS
T10128
Symbol
LCK
Name
(RefSeq) tyrosine-protein kinase Lck isoform X1
KO
K05856
lymphocyte cell-specific protein tyrosine kinase [EC:
2.7.10.2
]
Organism
ppyg Pongo pygmaeus (Bornean orangutan)
Pathway
ppyg04064
NF-kappa B signaling pathway
ppyg04380
Osteoclast differentiation
ppyg04517
IgSF CAM signaling
ppyg04650
Natural killer cell mediated cytotoxicity
ppyg04658
Th1 and Th2 cell differentiation
ppyg04659
Th17 cell differentiation
ppyg04660
T cell receptor signaling pathway
ppyg05135
Yersinia infection
ppyg05166
Human T-cell leukemia virus 1 infection
ppyg05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
ppyg05340
Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:
ppyg00001
]
09130 Environmental Information Processing
09132 Signal transduction
04064 NF-kappa B signaling pathway
129020410 (LCK)
09133 Signaling molecules and interaction
04517 IgSF CAM signaling
129020410 (LCK)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
129020410 (LCK)
04660 T cell receptor signaling pathway
129020410 (LCK)
04658 Th1 and Th2 cell differentiation
129020410 (LCK)
04659 Th17 cell differentiation
129020410 (LCK)
09158 Development and regeneration
04380 Osteoclast differentiation
129020410 (LCK)
09160 Human Diseases
09161 Cancer: overview
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
129020410 (LCK)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
129020410 (LCK)
09171 Infectious disease: bacterial
05135 Yersinia infection
129020410 (LCK)
09163 Immune disease
05340 Primary immunodeficiency
129020410 (LCK)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ppyg01001
]
129020410 (LCK)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
ppyg03036
]
129020410 (LCK)
Enzymes [BR:
ppyg01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
129020410 (LCK)
Protein kinases [BR:
ppyg01001
]
Non-receptor tyrosine kinases
SRC family
129020410 (LCK)
Chromosome and associated proteins [BR:
ppyg03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
129020410 (LCK)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2
SH3_1
SH3_2
SH3_9
ABC1
SH2_1
Haspin_kinase
SH3_16
SH3_3
Motif
Other DBs
NCBI-GeneID:
129020410
NCBI-ProteinID:
XP_054320661
LinkDB
All DBs
Position
1:complement(198475593..198510210)
Genome browser
AA seq
509 aa
AA seq
DB search
MGCGCSSHPEDDWMENIDVCENCHYPIVPLDGKGKLSIRNGSEVRDPLVTYEGSNPPASP
LQDNLVIALHSYEPSHDGDLGFEKGEQLRILEQSGEWWKAQSLTTGQEGFIPFNFVAKAN
SLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKH
YKIRNLDNGGFYISPRITFSGLHELVRHYTNASDGLCTRLSRPCQTQKPQKPWWEDEWEV
PRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRL
VRLYAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNY
IHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIK
SDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVCPDNCPEELYQLMRLCWKER
PEDRPTFDYLRSVLEDFFTATEGQYQPQP
NT seq
1530 nt
NT seq
+upstream
nt +downstream
nt
atgggctgtggctgcagctcacacccggaagatgactggatggaaaacattgatgtgtgt
gagaactgccattatcccatagtcccactggatggcaagggcaagctgtccatccgaaat
ggctctgaggtgcgggacccactggttacctacgaaggctccaatccaccggcttcccca
ctgcaagacaacctggttatcgccctgcacagctatgagccctctcacgacggagacctg
ggctttgagaagggggaacagctccgcatcctggagcagagcggcgagtggtggaaggcg
cagtccctgaccacgggtcaggaaggcttcatccccttcaattttgtggccaaagcgaac
agcctggagcccgaaccctggttcttcaagaaccttagccgcaaggacgcggagcggcag
ctcctggcgcccgggaacactcacggctccttcctcatccgggagagcgagagcaccgcg
ggatcgttttcactgtcggtccgggacttcgaccagaaccagggagaggtggtgaaacat
tacaagatccgtaatctggacaacggtggcttctacatctccccccgaatcactttttcc
ggcctgcatgaactggtccgccattacaccaatgcttcagatgggctctgtacacggttg
agccgcccctgccagacccagaagccccagaagccgtggtgggaggacgagtgggaggtt
cccagggagacgctgaagctggtggagcggctgggggctggacagttcggggaggtgtgg
atggggtactacaacgggcacacgaaggtggcggtgaagagcctgaagcagggcagcatg
tccccggacgccttcctggccgaggccaacctcatgaagcagctgcaacaccagcggctg
gttcggctctacgctgtggtcacccaggagcccatctacatcatcactgaatacatggag
aacgggagtctagtggattttctcaagaccccttcaggcatcaagttgaccatcaacaaa
ctcctggacatggcagcccaaattgcagaaggcatggcattcattgaagagcggaattat
attcatcgtgaccttcgggctgccaacattctggtgtctgacaccctgagctgcaagatt
gcagactttggcctagcacgcctcattgaggacaacgagtacacagctagggagggggcc
aagtttcccattaagtggacagcaccagaagccattaactatgggacattcaccatcaag
tcggatgtgtggtcttttgggatcctgctgacggaaattgtcacccatggccgcatccct
tacccagggatgaccaacccggaggtgattcagaacctggagcgaggctaccgcatggtg
tgccctgacaactgtccagaggagctgtaccaactcatgaggctgtgctggaaggagcgc
ccagaggaccggcccacctttgactacctgcgcagtgtgctggaggacttcttcacggcc
acagagggccagtaccagcctcagccttga
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