Pongo pygmaeus (Bornean orangutan): 129021880
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Entry
129021880 CDS
T10128
Symbol
PSEN2
Name
(RefSeq) presenilin-2 isoform X1
KO
K04522
presenilin 2 [EC:3.4.23.-]
Organism
ppyg Pongo pygmaeus (Bornean orangutan)
Pathway
ppyg04330
Notch signaling pathway
ppyg04722
Neurotrophin signaling pathway
ppyg05010
Alzheimer disease
ppyg05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
ppyg00001
]
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
129021880 (PSEN2)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
129021880 (PSEN2)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
129021880 (PSEN2)
05022 Pathways of neurodegeneration - multiple diseases
129021880 (PSEN2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
ppyg01002
]
129021880 (PSEN2)
Peptidases and inhibitors [BR:
ppyg01002
]
Aspartic peptidases
Family A22: presenilin family
129021880 (PSEN2)
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SSDB
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Gene cluster
GFIT
Motif
Pfam:
Presenilin
Motif
Other DBs
NCBI-GeneID:
129021880
NCBI-ProteinID:
XP_054323822
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All DBs
Position
1:complement(22637536..22663001)
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AA seq
448 aa
AA seq
DB search
MLTFMASDSEEEVCDERTSLMSAESPTPRSCQEGRQGPEDGENTAQWRSQENEEDGEEDP
DRYICSGVPGRPPGLEEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQLI
YTPFTEDTPSVGQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRCYKFIHGWLIMSSLMLL
FLFTYIYLGEVLKTYNVAMDYPTLLLTVWNFGAVGMVCIHWKGPLVLQQAYLIMISALMA
LVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVW
TVGMAKLDPSSQGALQLPYDPEMEEDSYDSFGEPSYPEVFEPPLTGYPGEELEEEEERGV
KLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALPISI
TFGLIFYFSTDNLVRPFMDTLASHQLYI
NT seq
1347 nt
NT seq
+upstream
nt +downstream
nt
atgctcacattcatggcctctgacagcgaggaagaagtgtgtgatgagcggacgtcccta
atgtcagccgagagccccacgccgcgctcctgccaggagggcaggcagggcccagaggac
ggagagaacactgcccagtggagaagccaggagaatgaggaggacggtgaggaggaccct
gaccgctacatctgtagtggggttcccgggcggccgccaggcctggaggaagagctgacc
ctcaaatacggggcgaagcacgtgatcatgttgtttgtgcctgtcactctgtgcatgatc
gtggtggtagccaccatcaagtctgtgcgcttctacacagagaagaatggacagctcatc
tacacgccattcactgaggacacgccctcggtgggccagcgcctcctcaactccgtgctg
aacaccctcatcatgatcagcgtcatcgtggttatgaccatcttcttggtggtgctctac
aagtaccgctgctacaagttcatccatggctggttgatcatgtcttcactgatgctgctg
ttcctcttcacttatatctaccttggggaagtgctcaagacctacaatgtggccatggac
taccccaccctcttgctgactgtctggaacttcggggcagtgggcatggtgtgcatccac
tggaagggccccctggtgctgcagcaggcttacctcatcatgatcagtgcgctcatggcc
ttggtgttcatcaagtacctcccagagtggtccgcgtgggtcatcctgggtgccatctct
gtgtacgatctggtggctgtgctgtgtcccaaagggcctctgagaatgctggtagaaact
gcccaggagagaaacgagcccatattccctgccctgatatactcatctgccatggtgtgg
acggtcggcatggcgaagctggacccctcctctcagggtgccctccagctcccctacgac
ccggagatggaagaagactcctatgacagttttggggagccttcataccccgaagtcttt
gagcctcccttgactggctacccaggggaggagctggaggaagaggaggaaaggggcgtg
aagctcggcctcggagacttcatcttctacagtgtgctggtgggcaaggcggcggccacg
ggcagcggggactggaataccacgctggcctgcttcgtggccatcctcattggcttgtgt
ctgaccctcctgctgcttgctgtgttcaagaaggcgctgcccgccctccccatctccatc
acgttcgggctcatcttttacttctccacggacaacctggtgcggccattcatggacacc
ctggcctcccatcagctctacatctga
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