Pongo pygmaeus (Bornean orangutan): 129025041
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Entry
129025041 CDS
T10128
Symbol
EIF2AK3
Name
(RefSeq) eukaryotic translation initiation factor 2-alpha kinase 3 isoform X1
KO
K08860
eukaryotic translation initiation factor 2-alpha kinase 3 [EC:
2.7.11.1
]
Organism
ppyg Pongo pygmaeus (Bornean orangutan)
Pathway
ppyg04137
Mitophagy - animal
ppyg04140
Autophagy - animal
ppyg04141
Protein processing in endoplasmic reticulum
ppyg04210
Apoptosis
ppyg04932
Non-alcoholic fatty liver disease
ppyg05010
Alzheimer disease
ppyg05012
Parkinson disease
ppyg05014
Amyotrophic lateral sclerosis
ppyg05020
Prion disease
ppyg05022
Pathways of neurodegeneration - multiple diseases
ppyg05160
Hepatitis C
ppyg05162
Measles
ppyg05168
Herpes simplex virus 1 infection
ppyg05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ppyg00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
129025041 (EIF2AK3)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
129025041 (EIF2AK3)
04137 Mitophagy - animal
129025041 (EIF2AK3)
09143 Cell growth and death
04210 Apoptosis
129025041 (EIF2AK3)
09160 Human Diseases
09172 Infectious disease: viral
05160 Hepatitis C
129025041 (EIF2AK3)
05162 Measles
129025041 (EIF2AK3)
05168 Herpes simplex virus 1 infection
129025041 (EIF2AK3)
09164 Neurodegenerative disease
05010 Alzheimer disease
129025041 (EIF2AK3)
05012 Parkinson disease
129025041 (EIF2AK3)
05014 Amyotrophic lateral sclerosis
129025041 (EIF2AK3)
05020 Prion disease
129025041 (EIF2AK3)
05022 Pathways of neurodegeneration - multiple diseases
129025041 (EIF2AK3)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
129025041 (EIF2AK3)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
129025041 (EIF2AK3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ppyg01001
]
129025041 (EIF2AK3)
Enzymes [BR:
ppyg01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
129025041 (EIF2AK3)
Protein kinases [BR:
ppyg01001
]
Serine/threonine kinases: Other
PEK family [OT]
129025041 (EIF2AK3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
PQQ_2
Kinase-like
Kdo
ABC1
OATP
Motif
Other DBs
NCBI-GeneID:
129025041
NCBI-ProteinID:
XP_054328476
LinkDB
All DBs
Position
12:45715508..45789822
Genome browser
AA seq
1113 aa
AA seq
DB search
MERAISPGLLVRALLLLLLGFAARTVAAGRARGLPAPTAEAAFGLGAAAAPTSATRVPAA
GAVAAAEVTVEDGEALPAAAGEQEPRGPEPDDETELRPRGRSLVIISTLDGRISALDPEN
HGKKQWDLDVGSGSLVSSSLSKPEVFGNKMIIPSLDGDLFQWDRDRESMETVPFTVESLL
ESSYKFGDDVVLVGGKSLTTYGLSAYSGKVRYICSALGCRQWDSDEMEQEEDILLLQRTQ
KTVRAVGPRSGNEKWNFSVGHFELRYIPDMETRAGFIESTFKPNENTEESKIISDVEEQE
AAIMDIVIKVSVADWKVMAFSKKGGHLEWEYQFCTPIASAWLLKDGKVIPISLFDDTSYT
SNDDVLEDEEDIVEAARGATENSVYLGMYRGQLYLQSSVRISEKFPSSPKALESVNNENA
IIPLPTIKWKPLIHSPSRTPVLVGSDEFDKCLSNDKFSHEEYSNGALSILQYPYDNGYYL
PYYKRERNKRSTQITVRFLDNPNYNKNIRKKDPVLLLHWWKEIVATILFCIIATTFIVRR
LFHPHPHRQRKESETQCQTENKYDSVSGEANDSSWNDIKNSGYISRYLTDFEPIQCLGRG
GFGVVFEAKNKVDDCNYAIKRIRLPNRELAREKVMREVKALAKLEHPGIVRYFNAWLEAP
PEKWQEKMDEIWLKDESTDWPLSSPSPMDAPSVKIRRMDPFSTKEHTEIIAPSPQRSRSF
SVGISCDQTSSSESQFSPLEFSGMDHEDTSESVDAAYNLQDSCLTDCDVEDGTMDGNHEG
HSFELCPSEASPYVRSRERTSSSIVFEDSGCDNASSKEEPKTNRLYIGNHCANKLTAFKP
TSSKSSEATLSISPPRPTTLSLDLTKNTTEKLQPSSPKVYLYIQMQLCRKENLKDWMNGR
CTIEERERSMCLHIFLQIAEAVEFLHSKGLMHRDLKPSNIFFTMDDVVKVGDFGLVTAMD
QDEEEQTVLTPMPAYARHTGQVGTKLYMSPEQIHGNSYSHKVDIFSLGLILFELLYPFST
QMERVRTLTDVRNLKFPPLFTQKYPCEYVMVQDMLSPSPMERPEATNIIENAVFEDLDFP
GKTVLRQRSRSLSSSGTKHSRQSNNSHSPLPSN
NT seq
3342 nt
NT seq
+upstream
nt +downstream
nt
atggagcgcgccatcagcccggggctgctggtacgggcgctgctgctgctgctgctgggg
ttcgcggcaaggacggtggccgcggggcgcgcccgtggcctcccagcgccgacggcggag
gcggcgttcggcctcggggcggccgctgctcccacctcagcgacgcgagtaccggcggcg
ggcgccgtggctgcggccgaggtgactgtggaggacggtgaggcgctgccggcagccgcg
ggcgagcaggagccgcggggtcctgaaccagacgatgagacagagttgcgaccgcgcggc
aggtcattagtaattatcagcactttagatgggagaatttctgccttggatcctgaaaat
catggtaaaaagcagtgggatttggatgtgggatccggttccttggtgtcatccagcctt
agcaaaccagaggtatttgggaataagatgatcattccttccctggatggagacctcttc
cagtgggaccgagaccgtgagagcatggaaacagttcctttcacagttgaatcacttctt
gaatcttcttataaatttggagatgatgttgttttggttggaggaaaatctctcactaca
tatggactcagtgcatatagtggaaaggtgaggtatatctgttcagctctgggttgtcgc
caatgggatagtgatgaaatggaacaagaggaagacatcctgcttctacagcgtacccaa
aaaactgttagagctgttggacctcgcagtggcaatgagaagtggaatttcagtgttggc
cactttgaacttcggtatattccagacatggaaacgagagccggatttattgaaagcacc
tttaagcccaatgagaacacagaagagtctaaaattatttcagatgtggaagaacaggaa
gctgccataatggacatagtgataaaggtttcggttgctgactggaaagttatggcattc
agtaagaagggaggacatctggaatgggagtaccagttttgtactccaattgcatctgcc
tggttacttaaggatgggaaagtcattcccatcagtctttttgatgatacaagttataca
tctaatgatgatgttttagaagatgaagaagacattgtagaagctgccagaggagccaca
gaaaacagtgtttacttgggaatgtatagaggccagctgtatctgcagtcatcagtcaga
atttcagaaaagtttccttcaagtcccaaggctttggaatctgtcaataatgaaaacgca
attattcctttgccaacaatcaaatggaaacccttaattcattctccttccagaactcct
gtcttggtaggatctgatgaatttgacaaatgtctcagtaatgataagttttctcatgaa
gaatatagtaatggtgcactttcaatcttgcagtatccatatgataatggttattatcta
ccatactacaagagggaaaggaacaaacgaagcacacagattacagtcagattcctcgac
aacccaaattacaacaagaatatccgcaaaaaggatcctgttcttctcttacactggtgg
aaagaaatagttgcaacaattttgttttgtatcatagcaacaacgtttattgtgcgcagg
cttttccatcctcatcctcacaggcaaaggaaggagtcagaaactcagtgtcaaactgaa
aataaatatgattctgtaagtggtgaagccaatgacagtagctggaatgacataaaaaac
tctggatatatatcacgatatctaactgattttgagccaattcaatgcctgggacgtggt
ggctttggagttgtttttgaagctaaaaacaaagtagatgactgcaattatgctatcaag
aggatccgtctccccaatagggaattggctcgggaaaaggtaatgcgagaagttaaagcc
ttagccaagcttgaacacccaggcattgttaggtatttcaatgcctggcttgaagcacca
ccagagaagtggcaagaaaagatggatgaaatttggctgaaagacgaaagcacagactgg
ccactcagctctcctagcccaatggatgcaccatcagttaaaatacgcagaatggatcct
ttctctacaaaagaacatactgaaatcatagctccttcaccacaaagaagcaggtctttt
tcagtagggatttcctgtgaccagacaagttcatctgagagccagttctcaccactggaa
ttctcaggaatggaccatgaggacaccagtgagtcagtggatgcagcatacaacctccag
gacagttgccttacagactgtgatgtggaagatggtactatggatggcaatcatgagggg
cactcctttgaactttgtccttctgaagcttctccttatgtaaggtcaagggagagaacc
tcctcttcaatagtatttgaagattctggctgtgataatgcttccagtaaagaagagccg
aaaactaatcgattgtatattggcaaccattgtgctaataaactaactgctttcaagccc
accagtagcaaatcttctgaagctacattgtctatttctcctccgagaccaaccacttta
agtttagatctcactaaaaacaccacagaaaaactccagcccagttcaccaaaggtgtat
ctttacattcaaatgcagctgtgcagaaaagaaaacctcaaagactggatgaatggacga
tgtaccatagaggagagagagaggagcatgtgtctgcacatcttcctgcagatcgcagag
gcagtggagtttcttcacagtaaaggactgatgcacagggacctcaagccatccaacata
ttctttacaatggatgatgtggtcaaagttggagactttgggttagtgactgcaatggac
caggatgaggaagagcagacggttctgacaccaatgccagcttatgccagacacacagga
caagtagggaccaaactgtatatgagcccagagcagattcatggaaacagctattctcat
aaagtggacatcttttctttaggcctgattctatttgaattgctgtacccattcagcact
cagatggagagagtcaggaccttaactgatgtaagaaatctcaaatttccaccattattt
actcagaaatatccttgtgagtatgtgatggttcaagacatgctctctccatcccctatg
gaacgacctgaagctacaaacatcattgaaaatgctgtatttgaggacttggactttcca
ggaaaaacagtgctcagacagaggtctcgctccttgagttcatcgggaacaaaacattca
agacagtccaacaactcccatagccctttgccaagcaattag
DBGET
integrated database retrieval system
