Pongo pygmaeus (Bornean orangutan): 129040360 Help Entry 129040360         CDS       T10128                                  Symbol ADCY1 Name (RefSeq) adenylate cyclase type 1   KO K08041   adenylate cyclase 1 [EC:4.6.1.1] Organism ppyg  Pongo pygmaeus (Bornean orangutan) Pathway ppyg00230   Purine metabolism ppyg01100   Metabolic pathways ppyg01522   Endocrine resistance ppyg04015   Rap1 signaling pathway ppyg04020   Calcium signaling pathway ppyg04022   cGMP-PKG signaling pathway ppyg04024   cAMP signaling pathway ppyg04062   Chemokine signaling pathway ppyg04072   Phospholipase D signaling pathway ppyg04081   Hormone signaling ppyg04082   Neuroactive ligand signaling ppyg04114   Oocyte meiosis ppyg04211   Longevity regulating pathway ppyg04213   Longevity regulating pathway - multiple species ppyg04261   Adrenergic signaling in cardiomyocytes ppyg04270   Vascular smooth muscle contraction ppyg04371   Apelin signaling pathway ppyg04540   Gap junction ppyg04611   Platelet activation ppyg04713   Circadian entrainment ppyg04714   Thermogenesis ppyg04720   Long-term potentiation ppyg04723   Retrograde endocannabinoid signaling ppyg04724   Glutamatergic synapse ppyg04725   Cholinergic synapse ppyg04727   GABAergic synapse ppyg04750   Inflammatory mediator regulation of TRP channels ppyg04911   Insulin secretion ppyg04912   GnRH signaling pathway ppyg04913   Ovarian steroidogenesis ppyg04914   Progesterone-mediated oocyte maturation ppyg04915   Estrogen signaling pathway ppyg04916   Melanogenesis ppyg04918   Thyroid hormone synthesis ppyg04921   Oxytocin signaling pathway ppyg04923   Regulation of lipolysis in adipocytes ppyg04925   Aldosterone synthesis and secretion ppyg04926   Relaxin signaling pathway ppyg04927   Cortisol synthesis and secretion ppyg04928   Parathyroid hormone synthesis, secretion and action ppyg04934   Cushing syndrome ppyg04935   Growth hormone synthesis, secretion and action ppyg04970   Salivary secretion ppyg04971   Gastric acid secretion ppyg04972   Pancreatic secretion ppyg04976   Bile secretion ppyg05032   Morphine addiction ppyg05142   Chagas disease ppyg05146   Amoebiasis ppyg05163   Human cytomegalovirus infection ppyg05166   Human T-cell leukemia virus 1 infection ppyg05200   Pathways in cancer ppyg05207   Chemical carcinogenesis - receptor activation ppyg05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:ppyg00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     129040360 (ADCY1)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     129040360 (ADCY1)    04371 Apelin signaling pathway     129040360 (ADCY1)    04020 Calcium signaling pathway     129040360 (ADCY1)    04072 Phospholipase D signaling pathway     129040360 (ADCY1)    04024 cAMP signaling pathway     129040360 (ADCY1)    04022 cGMP-PKG signaling pathway     129040360 (ADCY1)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     129040360 (ADCY1)    04081 Hormone signaling     129040360 (ADCY1)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     129040360 (ADCY1)   09144 Cellular community - eukaryotes    04540 Gap junction     129040360 (ADCY1)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     129040360 (ADCY1)    04062 Chemokine signaling pathway     129040360 (ADCY1)   09152 Endocrine system    04911 Insulin secretion     129040360 (ADCY1)    04923 Regulation of lipolysis in adipocytes     129040360 (ADCY1)    04912 GnRH signaling pathway     129040360 (ADCY1)    04913 Ovarian steroidogenesis     129040360 (ADCY1)    04915 Estrogen signaling pathway     129040360 (ADCY1)    04914 Progesterone-mediated oocyte maturation     129040360 (ADCY1)    04921 Oxytocin signaling pathway     129040360 (ADCY1)    04926 Relaxin signaling pathway     129040360 (ADCY1)    04935 Growth hormone synthesis, secretion and action     129040360 (ADCY1)    04918 Thyroid hormone synthesis     129040360 (ADCY1)    04928 Parathyroid hormone synthesis, secretion and action     129040360 (ADCY1)    04916 Melanogenesis     129040360 (ADCY1)    04925 Aldosterone synthesis and secretion     129040360 (ADCY1)    04927 Cortisol synthesis and secretion     129040360 (ADCY1)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     129040360 (ADCY1)    04270 Vascular smooth muscle contraction     129040360 (ADCY1)   09154 Digestive system    04970 Salivary secretion     129040360 (ADCY1)    04971 Gastric acid secretion     129040360 (ADCY1)    04972 Pancreatic secretion     129040360 (ADCY1)    04976 Bile secretion     129040360 (ADCY1)   09156 Nervous system    04724 Glutamatergic synapse     129040360 (ADCY1)    04727 GABAergic synapse     129040360 (ADCY1)    04725 Cholinergic synapse     129040360 (ADCY1)    04720 Long-term potentiation     129040360 (ADCY1)    04723 Retrograde endocannabinoid signaling     129040360 (ADCY1)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     129040360 (ADCY1)   09149 Aging    04211 Longevity regulating pathway     129040360 (ADCY1)    04213 Longevity regulating pathway - multiple species     129040360 (ADCY1)   09159 Environmental adaptation    04713 Circadian entrainment     129040360 (ADCY1)    04714 Thermogenesis     129040360 (ADCY1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     129040360 (ADCY1)    05207 Chemical carcinogenesis - receptor activation     129040360 (ADCY1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     129040360 (ADCY1)    05163 Human cytomegalovirus infection     129040360 (ADCY1)   09174 Infectious disease: parasitic    05146 Amoebiasis     129040360 (ADCY1)    05142 Chagas disease     129040360 (ADCY1)   09165 Substance dependence    05032 Morphine addiction     129040360 (ADCY1)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     129040360 (ADCY1)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     129040360 (ADCY1)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     129040360 (ADCY1) Enzymes [BR:ppyg01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      129040360 (ADCY1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N Adcy_cons_dom DUF6688 Motif Other DBs NCBI-GeneID:  129040360 NCBI-ProteinID:  XP_054350775 LinkDB All DBs Position 6:complement(40855978..41003427) Genome browser AA seq 1119 aa AA seqDB search MAGAPRGGGGGGGGAGEPGGAERAAGPSRRRGLRACDEEFACPELEALFRGYTLRLEQAA TLKALAVLSLLAGALALAELLGAPGPAPGLAKGSHPVHCVLFLALLVVTNVRSLQVPQLQ QVGQLALLFSLTFALLCCPFALGGPARGSAGAAGGPAAAEQGVWQLLLVTFVSYALLPVR SLLAIGFGLVVAASHLLVTATLVPAKRPRLWRTLGANALLFVGVNMYGVFVRILTERSQR KAFLQARSCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYIQRHD NVSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYCVSGL TQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDVWS NDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPGYGHERNSFLKTHNIETFFIVPSH RRKIFPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFSNVMTCEDDDKRRALR TASEKLRNRSSFSTNVVYTTPGTRVNRYISRLLEARQTELEMADLNFFTLKYKHVEREQK YHQLQDEYFTSAVVLTLILAALFGLVYLLIFPQSVAVLLLLVFCICFLVACVLYLHITRV QCFPGCLTIQIRTVLCIFIVVLIYSVAQGCVVGCLPWSWSSKPNSSLVVLSSGGQRTALP TLPCESTHHALLCCLVGTLPLAIFFRVSSLPKMILLSGLTTSYILVLELSGYTRTGGGAV SGRSYEPIVAILLFSCALALHARQVDIRLRLDYLWAAQAEEEREDMEKVKLDNRRILFNL LPAHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFNDFYIELDGNNMGVECLRLLNEI IADFDELMEKDFYKDIEKIKTIGSTYMAAVGLAPTSGTKAKKSISSHLSTLADFAIEMFD VLDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGRIQV TEEVHRLLRRCPYHFVCRGKVSVKGKGEMLTYFLEGRTDGNGSQIRSLGLDRKMCPYGRA GLQGRRPPVCPMPGVSVRAGLPPHSPGQYLPSAAAGKEA NT seq 3360 nt NT seq  +upstreamnt  +downstreamnt atggcgggggcgccgcgcggcggaggcggcggcggaggcggcgcgggcgagcccgggggc gccgagcgggcggccgggccaagccgccggcgcgggctccgggcgtgcgacgaggagttc gcttgcccagaactggaggcgctgttccgtggctacacgctgcggctggagcaggcggcc acgctgaaggcgctggccgttctcagcctgctggcgggcgcgctggcgctggcggagctg ctgggcgcgccggggcccgcgcccggcctggccaagggctcgcacccggtgcactgcgtc ctcttcctggcgctgctcgtggtaaccaatgtccggtccctgcaggtgccccagctgcag caggtcggccagctggcgctgctcttcagcctcaccttcgcgctgctctgctgtcctttc gcgctgggcggccccgcccggggttccgccggggccgctggggggccagcggccgccgaa caaggggtttggcagctccttttggtcaccttcgtgtcctatgccttgctgcccgtgcgc agcctgctggccatcggctttgggctcgtggtggctgcgtcgcacttgctggtcacagcc accttggtccctgccaagcgcccacgtctctggaggacgcttggcgccaatgccttgctc ttcgtcggtgtgaacatgtatggggtctttgtgcggattctgactgagcgttcgcagagg aaggcgttcctgcaggcccggagctgcatcgaggaccgactgaggctggaggatgagaac gagaagcaggagcggctgctcatgagcctcctgccccggaacgttgccatggagatgaag gaggacttcctgaagccccctgagaggattttccacaagatttacatccagaggcatgac aatgtgagcatcctgtttgctgacatcgtgggtttcacaggcttggcatcccagtgcaca gcccaggagctggtgaaactcctcaatgagctctttggcaagttcgacgaattagccacg gagaaccactgtcgccgcatcaagattctcggggactgctactactgcgtgtcgggcctc acccagcccaagactgaccatgcccactgctgtgtggagatgggactcgacatgatagat accatcacatccgtggctgaagccaccgaggtggacctgaacatgcgtgtgggtctgcac acgggcagggtcctctgtggtgtcctgggcttgcgcaagtggcagtacgacgtgtggtcc aatgatgtgaccttggccaatgtcatggaagccgctggcctgccagggaaggttcatatc acaaagacgaccctagcgtgcttgaatggggactacgaggtagaaccaggttacggacat gagaggaacagtttcttgaaaactcataacatcgaaaccttttttattgtgccatcccat cgccgaaagatatttccaggcctgattctctcagatataaaaccggccaaaagaatgaag ttcaagaccgtctgctacctgctggtgcagctcatgcactgccggaaaatgttcaaggcc gagatccccttctccaacgtcatgacctgtgaggacgatgacaagcggagggcattaaga acagcctcagaaaaactcagaaaccgctcatctttttctaccaacgttgtctacaccacc ccgggcactcgcgtcaacaggtacatcagccgcctcttagaagcccgccagacagagctg gagatggcagacctgaacttctttaccctgaagtacaaacatgtcgaacgggagcaaaag taccaccagcttcaggacgagtatttcaccagcgccgttgtcctcaccctcatcctggct gccttatttggccttgtctaccttctaatattcccacagagtgtggccgtcctgctcctg ctagtattctgcatctgcttcctggtggcctgtgtcctgtacctgcacatcacccgggtc cagtgttttccagggtgcctgacgattcagattcgcactgtcctgtgtattttcatagtg gtcttaatctactcagtagcccaaggttgcgtggtgggctgcctgccttggtcctggagc tccaagcccaacagttccctggtggtcctttcatctgggggccagcgcacagccctgccc accctgccctgcgagtctactcaccatgccctgctctgctgcctggtgggcaccctcccg ctagccatatttttccgggtgtcctccttgccaaaaatgatcctgctctccgggctcacc acgtcctacatcctcgttctggagctcagtggatacaccaggactgggggtggtgccgtc tccgggcgcagctacgagccgattgtggccatcctgctcttctcctgtgcgctggccctg catgccaggcaggtggacatcaggctgaggctggactacctctgggccgcacaggcagag gaggagcgagaggacatggagaaggtgaagctggacaacaggcgcatcctcttcaacctc ctgccggcccacgtcgcccagcacttcctcatgtccaaccctcggaacatggacctctac taccagtcctactcccaggtgggcgtcatgttcgcctccatccccaacttcaacgacttc tacatcgagctggacggcaacaacatgggggtggagtgtctgcggcttctcaatgagatc atcgccgactttgacgagctcatggaaaaagacttttacaaggacatagagaagatcaag accatcgggagcacctacatggccgctgtggggctagcacccacctcggggaccaaagct aagaagtccatctcctcccacctgagcacactggcggactttgccattgagatgtttgac gttctagatgaaatcaactaccagtcttacaacgacttcgtcctccgagttggcatcaat gttggccccgtggtggctggagtgattggcgctcgcaggccccagtacgacatctgggga aacacagtcaacgtggccagtcggatggacagcacaggggtccagggcagaatccaggtg actgaggaagtccaccgtctgctgagaaggtgcccctaccactttgtgtgccgaggcaaa gtcagtgtcaagggcaaaggcgagatgttgacatattttctagaaggcaggactgatgga aacggctcccaaatcaggtccctgggcttggatcggaaaatgtgtccatatgggagagct ggccttcagggcagacgtcccccggtgtgccctatgcctggcgtctcagtcagggctggg ctccctccacactccccaggccagtacctgccctctgcagcagctgggaaggaggcttag

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