Pongo pygmaeus (Bornean orangutan): 129043107
Help
Entry
129043107 CDS
T10128
Symbol
PTK2
Name
(RefSeq) focal adhesion kinase 1 isoform X1
KO
K05725
focal adhesion kinase 1 [EC:
2.7.10.2
]
Organism
ppyg Pongo pygmaeus (Bornean orangutan)
Pathway
ppyg01522
Endocrine resistance
ppyg04012
ErbB signaling pathway
ppyg04062
Chemokine signaling pathway
ppyg04148
Efferocytosis
ppyg04151
PI3K-Akt signaling pathway
ppyg04360
Axon guidance
ppyg04370
VEGF signaling pathway
ppyg04510
Focal adhesion
ppyg04517
IgSF CAM signaling
ppyg04518
Integrin signaling
ppyg04670
Leukocyte transendothelial migration
ppyg04810
Regulation of actin cytoskeleton
ppyg04935
Growth hormone synthesis, secretion and action
ppyg05100
Bacterial invasion of epithelial cells
ppyg05135
Yersinia infection
ppyg05146
Amoebiasis
ppyg05163
Human cytomegalovirus infection
ppyg05165
Human papillomavirus infection
ppyg05170
Human immunodeficiency virus 1 infection
ppyg05200
Pathways in cancer
ppyg05202
Transcriptional misregulation in cancer
ppyg05205
Proteoglycans in cancer
ppyg05208
Chemical carcinogenesis - reactive oxygen species
ppyg05222
Small cell lung cancer
ppyg05417
Lipid and atherosclerosis
ppyg05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ppyg00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
129043107 (PTK2)
04370 VEGF signaling pathway
129043107 (PTK2)
04151 PI3K-Akt signaling pathway
129043107 (PTK2)
09133 Signaling molecules and interaction
04517 IgSF CAM signaling
129043107 (PTK2)
04518 Integrin signaling
129043107 (PTK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
129043107 (PTK2)
09144 Cellular community - eukaryotes
04510 Focal adhesion
129043107 (PTK2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
129043107 (PTK2)
09150 Organismal Systems
09151 Immune system
04670 Leukocyte transendothelial migration
129043107 (PTK2)
04062 Chemokine signaling pathway
129043107 (PTK2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
129043107 (PTK2)
09158 Development and regeneration
04360 Axon guidance
129043107 (PTK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
129043107 (PTK2)
05202 Transcriptional misregulation in cancer
129043107 (PTK2)
05205 Proteoglycans in cancer
129043107 (PTK2)
05208 Chemical carcinogenesis - reactive oxygen species
129043107 (PTK2)
09162 Cancer: specific types
05222 Small cell lung cancer
129043107 (PTK2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
129043107 (PTK2)
05163 Human cytomegalovirus infection
129043107 (PTK2)
05165 Human papillomavirus infection
129043107 (PTK2)
09171 Infectious disease: bacterial
05135 Yersinia infection
129043107 (PTK2)
05100 Bacterial invasion of epithelial cells
129043107 (PTK2)
09174 Infectious disease: parasitic
05146 Amoebiasis
129043107 (PTK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
129043107 (PTK2)
05418 Fluid shear stress and atherosclerosis
129043107 (PTK2)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
129043107 (PTK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ppyg01001
]
129043107 (PTK2)
01009 Protein phosphatases and associated proteins [BR:
ppyg01009
]
129043107 (PTK2)
Enzymes [BR:
ppyg01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
129043107 (PTK2)
Protein kinases [BR:
ppyg01001
]
Non-receptor tyrosine kinases
FAK family
129043107 (PTK2)
Protein phosphatases and associated proteins [BR:
ppyg01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
129043107 (PTK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Focal_AT
Pkinase
FERM_N_2
FERM_C_FAK1
FERM_M
Kinase-like
Haspin_kinase
FERM_F2
ABC1
Motif
Other DBs
NCBI-GeneID:
129043107
NCBI-ProteinID:
XP_063525187
LinkDB
All DBs
Position
7:complement(153553748..153903710)
Genome browser
AA seq
1116 aa
AA seq
DB search
MWNPLTWMADCIAELGLLCIFQLQIQCLLQFPQSSSRITEEYDRYLASSKIMAAAYLDPN
LNHTPNSSTKTHLGTGIERSPGAMERVLKVFHYFESNSEPTTWASIIRHGDATDVRGIIQ
KIVDSHKVKHVACYGFRLSHLRSEEVHWLHVDMGVSSVREKYELAHPPEEWKYELRIRYL
PKGFLNQFTEDKPTLNFFYQQVKSDYMLEIADQVDQEIALKLGCLEIRRSYWEMRGNALE
KKSNYEVLEKDVGLKRFFPKSLLDSVKAKTLRKLIQQTFRQFANLNREESILKFFEILSP
VYRFDKECFKCALGSSWIISVELAIGPEEGISYLTDKGCNPTHLADFTQVQTIQYSNSED
KDRKGMLQLKIAGAPEPLTVTAPSLTIAENMADLIDGYCRLVNGASQSFIIRPQKEGERA
LPSIPKLANSEKQGMRTHAVSVSDEISGDETDDYAEIIDEEDTYTMPSKSYGIDEARDYE
IQRERIELGRCIGEGQFGDVHQGVYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMR
QFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAY
LESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINF
RRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMT
KCWAYDPSRRPRFTELKAQLSTILEEEKAQQEERMRMESRRQATVSWDSGGSDEAPPKPS
RPGYPSPRSSEGFYPSPQHMVQTNHYQVSGYPGSHGITAMAGSIYPGQASLLDQTDSWNH
RPQEIAMWQPNVEDSTALDLRGIGQVLPTHLMEERLIRQQQEMEEDQRWLEKEERFLKPD
VRLSRGSIDREDGSLQGPIGNQHIYQPVGKPDPAAPPKKPPRPGAPGHLGSLASLSSPAD
SYNEGVKLQPQEISPPPTANLDRSNDKVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKE
VGLALRTLLATVDETIPLLPASTHREIEMAQKLLNSDLGELINKMKLAQQYVMTSLQQEY
KKQMLTAAHALAVDAKNLLDVIDQARLKMLGQTRPH
NT seq
3351 nt
NT seq
+upstream
nt +downstream
nt
atgtggaacccgctgacatggatggctgactgtattgcagaactggggctcctttgcatc
ttccagttacaaattcagtgccttctgcagtttccccagagctcctcaagaataacggaa
gaatatgacagatacctagcatctagcaaaataatggcagctgcttaccttgaccccaac
ttgaatcacacgccaaattcgagtactaagactcacctgggtactggtatagaacgttct
cctggtgcgatggagcgagtattaaaggtctttcattattttgaaagcaatagtgagcca
accacctgggccagtattatcaggcatggagatgctactgatgtcaggggcatcattcag
aagatagtggacagtcacaaagtaaagcatgtggcctgctatggattccgcctcagtcac
ctgcggtcagaggaggttcactggcttcacgtggatatgggcgtctccagtgtgagggag
aagtatgagcttgctcacccaccagaggagtggaaatatgaattgagaattcgttatttg
ccaaaaggatttctaaaccagtttactgaagataagccaactttgaatttcttctatcaa
caggtgaagagcgattatatgttagagatagctgatcaagtggaccaggaaattgctttg
aagttgggttgtctagaaatacggcgatcatactgggagatgcggggcaatgcactagaa
aagaagtctaactatgaagtattagaaaaagatgttggtttaaagcgattttttcctaag
agtttactggattctgtcaaggccaaaacactaagaaaactgatccaacaaacgtttaga
caattcgccaaccttaatagagaagaaagtattctgaaattctttgagatcctgtctcca
gtctacagatttgataaggaatgcttcaagtgtgctcttggttcaagctggattatttca
gtggaactggcaatcggcccagaagaagggatcagttacctaacggacaagggctgcaat
cccacacatcttgctgacttcactcaagtgcaaaccattcagtattcaaacagtgaagac
aaggacagaaaaggaatgctacaactaaaaatagcaggtgcacccgagcctctgacagtg
acggcaccatccctaaccattgcggagaatatggctgacctgatagatgggtactgccgg
ctggtgaatggagcctcacagtcatttatcatcagaccccagaaagaaggtgaacgggct
ttgccatcaataccaaagttggccaacagcgaaaagcaaggcatgcggacacacgccgtc
tctgtgtcagatgaaattagtggggacgaaacagatgattatgctgagattatagatgaa
gaagatacttacaccatgccctcaaaaagctatggaatagatgaagccagggattatgag
attcaaagagaaagaatagaacttggacgatgtattggagaaggccaatttggagatgta
catcaaggcgtttatatgagtccagagaatccagctttggcggttgcaattaaaacatgt
aaaaactgtacttcggacagcgtgagagagaaatttcttcaagaagccttaacaatgcgt
cagtttgaccatcctcatattgtgaagctgattggagtcatcacagagaatcctgtctgg
ataatcatggagctgtgcacacttggagagctgaggtcatttttgcaagtaaggaaatac
agtttggatctagcatctttgatcctgtatgcctatcagcttagtacagctcttgcatat
ctagagagcaaaagatttgtacacagggacattgctgctcggaatgttctggtgtcctca
aatgattgtgtaaaattaggagactttggattatcccgatatatggaagatagtacttac
tacaaagcttccaaaggaaaattgcctattaaatggatggctccagagtcaatcaatttt
cgacgttttacctcagctagtgacgtatggatgtttggtgtgtgtatgtgggagatactg
atgcatggtgtgaagccttttcaaggagtgaagaacaatgatgtaatcggtcgaattgaa
aatggggaaagattaccaatgcctccaaattgtcctcctaccctctacagccttatgacg
aaatgctgggcctatgaccccagcaggcggcccaggtttactgaacttaaagctcagctc
agcacaatcctggaggaagagaaggctcagcaagaagagcgcatgaggatggagtccaga
agacaggccacagtgtcctgggactccggagggtctgatgaagcgccgcccaagcccagc
agaccgggttatcctagtccgaggtccagtgaaggattttatcccagcccacagcacatg
gtacaaaccaatcattaccaggtttctggctaccctggttcacatggaatcacagccatg
gctggtagcatctatccaggtcaggcatctcttttggaccaaacagattcatggaatcat
agacctcaggagatagcaatgtggcagcccaatgtggaggactctacagcattggacctg
cgagggattgggcaagtgttgccaacccatctgatggaagagcggctaatccgacagcaa
caggaaatggaagaagatcagcgctggctggaaaaagaggaaagatttctgaaacctgat
gtgagactctctcgaggcagtattgacagggaggatggaagtcttcagggtccgattgga
aaccaacatatatatcagcctgtgggtaaaccagatcctgcagctccaccaaagaaaccg
cctcgccctggagctcccggtcatctgggaagccttgccagcctcagcagccctgctgac
agctacaacgagggtgtcaagcttcagccccaggaaatcagtccccctcctactgccaac
ctggaccggtcgaatgataaggtgtacgagaatgtgacgggcctggtgaaagctgtcatc
gagatgtccagtaaaatccagccagccccaccagaggagtatgtccctatggtgaaggaa
gtcggcttggccctgaggacgttattggccactgtggatgagaccattcccctcctacca
gccagcacccaccgagagattgagatggcacagaaactattgaactctgacctgggtgag
ctcatcaacaagatgaaactggcccagcagtatgtcatgaccagcctccagcaagagtac
aaaaagcaaatgctgactgctgctcacgccctggctgtggatgccaaaaacttactcgat
gtcattgaccaagcaagactgaaaatgcttgggcagacgagaccacactga
DBGET
integrated database retrieval system
