KEGG   Podarcis raffonei (Aeolian wall lizard): 128412483
Entry
128412483         CDS       T09310                                 
Symbol
PAK1
Name
(RefSeq) serine/threonine-protein kinase PAK 1 isoform X1
  KO
K04409  p21-activated kinase 1 [EC:2.7.11.1]
Organism
praf  Podarcis raffonei (Aeolian wall lizard)
Pathway
praf04010  MAPK signaling pathway
praf04012  ErbB signaling pathway
praf04510  Focal adhesion
praf04625  C-type lectin receptor signaling pathway
praf04810  Regulation of actin cytoskeleton
praf05132  Salmonella infection
Brite
KEGG Orthology (KO) [BR:praf00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    128412483 (PAK1)
   04012 ErbB signaling pathway
    128412483 (PAK1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    128412483 (PAK1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    128412483 (PAK1)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    128412483 (PAK1)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    128412483 (PAK1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:praf01001]
    128412483 (PAK1)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:praf04131]
    128412483 (PAK1)
   03036 Chromosome and associated proteins [BR:praf03036]
    128412483 (PAK1)
Enzymes [BR:praf01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     128412483 (PAK1)
Protein kinases [BR:praf01001]
 Serine/threonine kinases: STE group
  STE20 family
   128412483 (PAK1)
Membrane trafficking [BR:praf04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    128412483 (PAK1)
 Endocytosis
  Macropinocytosis
   Kinases
    128412483 (PAK1)
Chromosome and associated proteins [BR:praf03036]
 Eukaryotic type
  Sister chromatid separation proteins
   Aurora kinases
    Regulators of Aurora kinases
     128412483 (PAK1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr PBD ABC1 Pkinase_fungal Kinase-like APH DSHCT
Other DBs
NCBI-GeneID: 128412483
NCBI-ProteinID: XP_053241419
LinkDB
Position
4:complement(11172113..11283465)
AA seq 545 aa
MSNNGLEAEDKPPAPPMRNTSTMIGSGNKEAGPLNHGSKPLPPNPEEKKKRDRFYRSILP
GDKTNKKKEKERPEISLPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTSNITKSEQKKN
PQAVLDVLEFYNSKKTSNSQKYMSFTDKSAEDYNSSNTLNVKAVSETPAVPPVSEDEDDE
DDAAPPPVIAPRPEHTKSIYTRSVIEPLPPAPTRDVATSPIPSPSENSTTPPDTLARSTE
KQKKKPKMTDEEILEKLRGIVSVGDPKKKYTSFEKIGQGASGTVYTAIDVATGQEVAIKQ
MNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETC
MDEGQIAAVCRECLQALEFLHANQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSK
RSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNG
TPELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHQFLKIAKPLSSLTPLIIAAKEA
AKNNH
NT seq 1638 nt   +upstreamnt  +downstreamnt
atgtccaataatggcctagaagcagaagacaagcccccggctcctccaatgaggaacacc
agcacgatgataggcagcgggaacaaagaggcgggacccttgaaccacggctccaaacct
ttgcctcctaatccggaagagaagaagaagagggaccgcttttaccgctccatcttaccg
ggagacaaaaccaacaagaagaaggagaaagagcgccctgagatctcactcccttccgac
tttgagcacacgattcacgttgggtttgatgctgtcacaggcgaattcacggggatgcct
gagcaatgggcccgcttgctgcaaacctccaacatcaccaaatcggagcagaagaagaac
cctcaggccgtgctcgacgtcctagagttctacaattccaaaaagacctccaatagccag
aagtatatgagcttcacagataaatctgcagaagactataactcctccaacacactgaat
gtgaaggcggtatctgagacccccgccgtcccccctgtgtcagaggacgaagatgatgaa
gacgatgctgcccctcccccggtcatcgctccccggcccgagcacacgaagtccatatac
acccggtcggtgatcgaaccccttcctccagccccgacccgagacgtggccacctctccg
atcccatcgccttccgaaaacagcacgacccctccagacacgttggcgaggagtacggag
aagcagaaaaagaaaccgaaaatgacagacgaggaaatcttggagaaattaagaggtatt
gtgagtgtgggtgaccccaagaagaaatatacaagttttgagaagatcgggcaaggagct
tcagggacagtttacacggcgatcgatgtagctacaggacaggaagttgcaattaagcag
atgaacttgcagcaacagcccaagaaggagctgataattaatgaaattctcgtcatgagg
gaaaacaagaaccccaacattgtcaactatctggacagttaccttgtgggggatgaattg
tgggtagtcatggagtatttggcaggcggttccttgacagacgtggtgacagagacctgc
atggatgaagggcagattgccgccgtgtgccgggagtgtctgcaggccttggaattcctc
catgccaaccaagtcatccacagggacatcaagagtgacaatatcttgctggggatggat
gggtctgtcaagctaaccgatttcggcttctgtgctcagatcactcccgagcaaagcaag
cgcagcaccatggttgggacgccatattggatggcgcccgaggtggtgacgagaaaagcc
tatgggcccaaagtggacatctggtctctggggataatggccattgaaatgatagagggg
gaacctccgtacctcaacgaaaatccactgagggctttatatcttattgctaccaacggg
acccccgagctgcagaacccagagaagctttcgcccatctttagagacttccttaatcgc
tgcctcgagatggatgtggagaagagggggtctgcgaaagagctcctccagcaccagttt
ctcaaaatcgccaagcccctctccagcctcactcctctgatcatcgcggcgaaggaggca
gcgaagaacaaccactga

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