KEGG   Poecilia reticulata (guppy): 103477979
Entry
103477979         CDS       T05149                                 
Name
(RefSeq) 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase-like
  KO
K00070  3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:1.1.1.145 5.3.3.1]
Organism
pret  Poecilia reticulata (guppy)
Pathway
pret00140  Steroid hormone biosynthesis
pret01100  Metabolic pathways
Module
pret_M00107  Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
pret_M00110  C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
pret_M00976  C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:pret00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    103477979
Enzymes [BR:pret01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.145  3beta-hydroxy-Delta5-steroid dehydrogenase
     103477979
 5. Isomerases
  5.3  Intramolecular oxidoreductases
   5.3.3  Transposing C=C bonds
    5.3.3.1  steroid Delta-isomerase
     103477979
SSDB
Motif
Pfam: 3Beta_HSD Epimerase GDP_Man_Dehyd NAD_binding_4 Polysacc_synt_2 NAD_binding_10 NmrA KR RmlD_sub_bind adh_short
Other DBs
NCBI-GeneID: 103477979
NCBI-ProteinID: XP_008429615
UniProt: A0A3P9MU19
LinkDB
Position
LG2:12627923..12638009
AA seq 374 aa
MSLRGDVCVVTGACGFLGKRLVRLLLEEEKASEIRLLDRDVQTQVLESLEDCRGETTLSV
FEGDIRDGDFLRKALRGASTVFHIASLIDVTESMEYSEMYGVNVKGTQLLLETCIQENVV
SFIYTSTVEVMGPNPRGEPIINGTEDTVYDTTLKFNYSKTKKEAEDRTLQADGETLQNGG
RLSTCALRPTYIYGDGCRFLLCHMGDGIRNKNVLFRMSVPEAHVNPVYVGNAAFAHLQAA
RSLKDPQKRNAVGGRFYYLSDDTPPMSYSDFNHVLMSPLGFSIQDKLVLPLRLFYILCFL
LEALCTILRPFVRIVPPMNRQLLTLLNTSFTFSYEKAKRDLGYVPRYSWEEARRRTTEWL
ASQLPAEREKIMSS
NT seq 1125 nt   +upstreamnt  +downstreamnt
atgtctctgagaggtgatgtttgcgtggtgacgggagcctgtggattcctggggaagagg
ctcgtccggctgctgctggaagaggagaaagcgtccgagatccggctgctggacagagac
gtgcagacgcaggttttggagagtctggaggactgcagaggcgagacaacactgagcgtc
ttcgagggggacatcagagacggggatttcttgagaaaagccttgcgtggcgcatcgacc
gtcttccacatcgcttccctcatcgacgttaccgagtcaatggagtacagtgagatgtac
ggagtcaacgtcaaaggaactcagctgcttttggagacgtgtatccaagagaacgtggtc
tccttcatctacaccagcacggtggaagtgatgggcccaaacccccgaggagagccgatc
atcaatggcaccgaggacacggtctacgacaccaccctgaagttcaactacagcaagacc
aaaaaggaggcggaggacagaacccttcaggccgacggtgagacgctccaaaacggaggc
cgcctctccacctgcgccctcaggcccacctacatctacggggacggctgccgcttcctg
ctgtgccacatgggcgacggcatacgaaacaagaacgtcctcttccgcatgtccgtgccg
gaggcccatgtgaacccggtctacgtgggcaacgcagcctttgctcacctccaggcggcc
cgcagcctcaaagatccacaaaaaagaaacgcggtcggagggaggttttactacctctcc
gacgacaccccgcctatgagttactcggacttcaaccacgttttgatgtctcccctcggc
ttcagcattcaggacaaactcgtgctgccgcttcgcctcttctacatcctgtgttttctc
ctggaggcgctctgcacgatcctgcgaccgtttgtccgcatcgtgccgccgatgaaccgg
cagctgctcaccttgttgaacacttcgttcaccttctcctacgagaaagccaagcgggac
ctgggctacgtcccccgctacagctgggaggaagcgcgccgacgcaccaccgaatggctc
gcctcacagctgccagcggagagggaaaaaattatgtccagctaa

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