Phodopus roborovskii (desert hamster): 127217141 Help Entry 127217141         CDS       T08852                                  Symbol Irs4 Name (RefSeq) insulin receptor substrate 4   KO K17446   insulin receptor substrate 4 Organism prob  Phodopus roborovskii (desert hamster) Pathway prob04022   cGMP-PKG signaling pathway prob04068   FoxO signaling pathway prob04081   Hormone signaling prob04140   Autophagy - animal prob04152   AMPK signaling pathway prob04211   Longevity regulating pathway prob04213   Longevity regulating pathway - multiple species prob04910   Insulin signaling pathway prob04920   Adipocytokine signaling pathway prob04923   Regulation of lipolysis in adipocytes prob04930   Type II diabetes mellitus prob04935   Growth hormone synthesis, secretion and action prob05010   Alzheimer disease Brite KEGG Orthology (KO) [BR:prob00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     127217141 (Irs4)    04022 cGMP-PKG signaling pathway     127217141 (Irs4)    04152 AMPK signaling pathway     127217141 (Irs4)   09133 Signaling molecules and interaction    04081 Hormone signaling     127217141 (Irs4)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     127217141 (Irs4)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     127217141 (Irs4)    04923 Regulation of lipolysis in adipocytes     127217141 (Irs4)    04920 Adipocytokine signaling pathway     127217141 (Irs4)    04935 Growth hormone synthesis, secretion and action     127217141 (Irs4)   09149 Aging    04211 Longevity regulating pathway     127217141 (Irs4)    04213 Longevity regulating pathway - multiple species     127217141 (Irs4)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     127217141 (Irs4)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     127217141 (Irs4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  IRS PH_11 PH_8 PH Motif Other DBs NCBI-GeneID:  127217141 NCBI-ProteinID:  XP_051033965 LinkDB All DBs Position Unknown AA seq 1243 aa AA seqDB search MASCSFAGDRALRRLRAAAAAASAALAAVATTPLLSSGTPTALIGTGSSCPGAMWLSTAT GSRSDSESEEEDLPVGDEVCKRGYLRKQKHGHRRYFVLKLETEDAPARLEYYENARKFRH SVRAAAAAAAAAASGAAVPALIPPRRVIILYQCFSVSQRADARYRHLIALFTQDEYFAMV AENESEQESWYLLLSRLILESKRRRCGTLGAQPDGEPAALAAAAAAEPPFYKDVWQVVIK PRGLGHRKELSGVFRLCLTDEEVVFVRLNTEVASVVVQLLSIRRCGHSEQYFFLEVGRST VIGPGELWMQVDDCVVAQNMHELFLEKMRALCADEYRARCRTYSISVGAHLLTLLSTRRH LGLLPVEPGGWLRRSRFEQFCHLRAIGEREEEMLLNRRFIPREPRPPSRRGRGHVPRARR ARRALSVPPSFSRRLAPSPPVRVSHPEEASNDRACEASGSNSGNSEEKDKEGEEGNEGDY MPMNNWGSGNGRGSGGGQGSSGQGSSSQSSGGNQCSGGRQGSGGGQGSGGQGSGGRGSGG QGAGGNQCSGNGQGTAGGHGSGGGQWPGGGHGSGGGRAPGDGHGSGGGKNSGGGKGSGSG KNSDDGDRGKSVKKRSYFGKFTHSKQQQTLPPPPPPPPPAGATGGKSKSGGRFRLYFCAD RGATKERKEAKEVRDRETPEGATRGSHRARAYDEDEDDPYVPMRPGVAAPLACSSDYMPM APQNSSATKKRHSRSPFEDSRGYMMMFPRVSPPPPAPSPPKAPDTNKEDDSKDNDSDSDY MFMAPGAGAIPKNPPNPQGGSSSKSWSSYFSLPSPFQSSPLGQSDHSEYVPMLPGKYLGR GLDKEASFSQDTKDVGSFSKPGDSGSPSKPSDDESPVNKAKRPNRLSFLAKGNKIKPKPV KPTQEQRGADSSRDYINIDFIKRERPVPAPSAQGLPDSWGLITDPRRTAFSGYLNIEIGV PFPNPAIRLSDLLRVLPGANSIYLAGARWPFRPFPGSATRRIVEEGEYIEVIFNPAMRPV VPFADSAIRFDVQTGQMYVVDPFSECCMDISLSPGRCSEPPPVARLLQEEVQERRRPQSR SQSLFANTRAAVSAFPTDSLDRDFPAASAGVVVPAGAPILAVSRALAVVSALAAAPGFGA IFAGFQATVRFDSASARRFQPVANALGAQAVRGAQDIAAGWNPEALNQAARGEELAARAA APPPPPRQRRVLRPPERADSEDNDEDDDEIYVRMDFARRDYKK NT seq 3732 nt NT seq  +upstreamnt  +downstreamnt atggcgagttgctccttcgctggcgaccgagcactaaggagactgagagctgcagcagca gcagcgtcagcagctctagcagcagtggcgaccaccccgcttctttcctcgggaaccccg accgcactcattgggaccgggtcgtcctgtccgggagccatgtggctctccacggccact ggctcccggtcagactctgagtccgaagaggaagacctccccgtcggggatgaagtctgc aaacgcggctacctgaggaagcagaagcatgggcacaggcgttacttcgtgctcaaactc gagaccgaagacgccccggctcggctggaatactatgaaaatgccaggaagttccggcac agtgtccgcgcagcggcggctgcggcagcggctgccgcctcgggtgctgcggtccccgcg ctcatcccaccgaggcgcgtgatcatcctgtaccagtgcttctccgtgagccaacgagct gatgccaggtaccgacaccttattgcccttttcacccaggacgagtacttcgcgatggtg gccgagaacgagtcggaacaagaaagctggtacttgctcctcagccgcctcatcctcgag agcaagcgccgccgctgcggcacgctaggcgcgcagccggacggagagccggcggccctg gcggcagcagcggcggcggagccacccttctacaaagatgtgtggcaggtagtaatcaaa cccagggggctggggcacagaaaagagctgagcggcgtgttccggctgtgtcttaccgac gaagaggttgtgtttgtaaggctcaatactgaagtggccagtgtggtcgtccagctcctg agtattcgtcgctgtgggcactcggagcagtactttttcttggaagtcggcaggtccacg gtcatcggtccaggggagctgtggatgcaggtagatgactgtgtggtggcccaaaatatg catgagctgtttttggagaagatgagagccttgtgcgcagatgaataccgagcccggtgc cgcacctacagcatcagtgttggcgcccacctgttaaccctgctgtccactaggaggcac ctgggcttgctccccgtggagcccggcggctggctccgaagatcccgctttgagcagttt tgccacctcagggctatcggagaaagggaagaggagatgctccttaacaggcgcttcata cccagggagcctcggcctccctccaggagaggaagggggcacgtgcccagagcccgcagg gccaggagagcgctttcagtaccacccagcttttcccgccgcttagcacctagcccgccg gtacgtgtctcacaccctgaagaagcctccaatgacagagcttgtgaagcctctggctcc aactctggcaactctgaagaaaaagacaaggaaggcgaggaaggaaacgaaggtgattac atgcccatgaacaactggggctcaggaaacggccggggctcaggaggtggacagggctca agtggccaaggctccagcagccagagctcaggagggaaccagtgctcaggtggcaggcag ggttctggaggtggccagggctcaggaggccagggctcaggaggccggggttcaggaggt cagggtgctggaggaaaccagtgttcaggaaatggccagggcacagcaggtggccatggc tcaggtggaggccagtggcctggcggtggccatggctcaggtggtggccgggcacctgga gatggtcacggctcaggtggtggcaagaactcaggaggaggcaagggttcaggaagtggc aaaaactccgatgatggtgaccgtgggaaatctgtgaagaaaagatcatactttggtaaa ttcactcacagcaagcaacagcaaacgctgcctccacctccacctccacccccgccagcc ggagcaactggtggtaaaagcaagtcggggggaagattccgactttatttctgtgcagac agaggagccacaaaagaacgcaaagaagccaaagaggtgagagatagggaaaccccagaa ggagcaacccgggggtcccaccgagccagagcttacgatgaagacgaggatgacccatat gtgccaatgaggccaggggtggctgcccctctcgcatgttccagtgactatatgccaatg gctcctcaaaattcctctgctaccaaaaagcgccactctaggtcaccattcgaagactcc agagggtacatgatgatgtttcccagagtgagtccaccaccacctgccccaagtcctcca aaagcaccggataccaataaagaggatgactctaaggacaatgacagtgacagtgactac atgtttatggctcctggagcaggtgcgattcctaaaaatcctcccaatcctcagggaggt tcttcctccaaaagttggagctcttacttctctctgccaagtccttttcagagttcaccc ttgggacagagcgaccatagtgaatatgttcccatgttgcctgggaagtacctggggagg ggtctagacaaagaagcctcctttagccaggacaccaaagatgtggggtcattctcaaaa cctggagatagcgggtcaccttcaaagccttcagatgatgagtccccagtgaacaaggct aagagacctaaccgactttcttttcttgcaaaaggaaacaaaatcaagcccaaaccagta aagcccacacaggagcagagaggagctgacagctctcgtgactatatcaacattgacttc attaaaagagagcgccctgtgccagctccctctgctcaaggactgccagattcttggggc ttaattactgaccccagacgcacagctttttccggttacctgaatattgaaatcggggtg ccctttccaaatccagcaatccgcctctcagatcttttaagagttctaccaggtgccaac tcgatctatctggccggtgctaggtggccctttcgtcctttcccaggcagtgctacaaga cgtattgtggaagagggtgaatacattgaagtaattttcaacccagccatgagaccagtc gtgccttttgctgacagtgccattcgctttgatgttcaaaccggtcaaatgtatgtagtc gacccattttctgagtgctgtatggacatttctctctctcctggtcgatgctctgaaccg ccacctgtagctaggctgctgcaggaggaagtgcaggagagaagacgcccacaaagccgc tcccaaagtttatttgctaacacccgagccgctgtctctgctttcccaactgacagcttg gacagagattttcccgccgcttctgccggggttgttgttccagctggggcgcccatcttg gcagtgagccgggctttagctgtggtctctgcgctcgcagcggcccccggttttggcgct atctttgccggcttccaggccactgtcagatttgactccgcctctgctcgccggttccaa cctgttgcgaatgctctcggtgcccaggctgtaagaggggcccaggacattgccgcaggc tggaatcctgaagcccttaaccaagctgccagaggtgaggaactggcggcccgcgcagca gctcccccaccgccacctcgccagcgacgggtgctgagacccccagagagagctgactct gaggacaacgacgaagatgacgacgagatttacgtgagaatggactttgccagacgtgac tacaagaagtga

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