Phodopus roborovskii (desert hamster): 127217225 Help Entry 127217225         CDS       T08852                                  Symbol Jak3 Name (RefSeq) tyrosine-protein kinase JAK3   KO K11218   Janus kinase 3 [EC:2.7.10.2] Organism prob  Phodopus roborovskii (desert hamster) Pathway prob04062   Chemokine signaling pathway prob04151   PI3K-Akt signaling pathway prob04217   Necroptosis prob04550   Signaling pathways regulating pluripotency of stem cells prob04630   JAK-STAT signaling pathway prob04658   Th1 and Th2 cell differentiation prob04659   Th17 cell differentiation prob05161   Hepatitis B prob05162   Measles prob05166   Human T-cell leukemia virus 1 infection prob05169   Epstein-Barr virus infection prob05200   Pathways in cancer prob05203   Viral carcinogenesis prob05223   Non-small cell lung cancer prob05340   Primary immunodeficiency Brite KEGG Orthology (KO) [BR:prob00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     127217225 (Jak3)    04151 PI3K-Akt signaling pathway     127217225 (Jak3)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     127217225 (Jak3)   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     127217225 (Jak3)  09150 Organismal Systems   09151 Immune system    04658 Th1 and Th2 cell differentiation     127217225 (Jak3)    04659 Th17 cell differentiation     127217225 (Jak3)    04062 Chemokine signaling pathway     127217225 (Jak3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     127217225 (Jak3)    05203 Viral carcinogenesis     127217225 (Jak3)   09162 Cancer: specific types    05223 Non-small cell lung cancer     127217225 (Jak3)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     127217225 (Jak3)    05161 Hepatitis B     127217225 (Jak3)    05162 Measles     127217225 (Jak3)    05169 Epstein-Barr virus infection     127217225 (Jak3)   09163 Immune disease    05340 Primary immunodeficiency     127217225 (Jak3)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:prob01001]     127217225 (Jak3) Enzymes [BR:prob01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      127217225 (Jak3) Protein kinases [BR:prob01001]  Non-receptor tyrosine kinases   JAK family [OT]    127217225 (Jak3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase FERM_F2 SH2_1 FERM_F1 Jak1_Phl ABC1 Kinase-like Haspin_kinase Motif Other DBs NCBI-GeneID:  127217225 NCBI-ProteinID:  XP_051034095 UniProt:  A0AAU9YWW8 LinkDB All DBs Position Unknown AA seq 1100 aa AA seqDB search MAPPSEETPLIPQRSCSLSSSEAGSLHVLLPPRGSGPPRRLSFSFGDYLAEDLCVQAAKA CGILPVYHPLFALATEDLSCWFPPSHIFSMEDMDTQVLVYRLRFYFPDWFGLETCHRFGR RKDLTSAILDLHVLEHLFAQHRSDLLSGRLSVGLSLKEQGECLSLAVLDLAQMAREQAQR PGELLKTVSYKACLPPGLRDLIQSMSFVTRRRIRRTVLQALRRVVACQADRYSLMAKYIL DLERLHPAATAETFRVGLPSAQEGAALLRVTGGSGIAWSSGDQEFFQTFCDFPEIVDVSI KQAPRVGPAGEHRLVTVTRMDSHILEAEFPGLPEALSFLALVDGYFRLVCDSRHFFCKEV APPRLLEEVAELCHGPITLDFAIYKLKAAGSLPGSYILRRSPQDYDSFLLTACVQTPLGP DYKGCLIRQDPTGAFSLVGLSQPHRSLRELLASCWHSGLHVDGAALNLTFCCTPRPKEKS NLIIVRRGCTPSPPPGRAPSCCALTQLTFHTISADSLEWHENLGHGSFTKIYRGRLLEVV DGETHDTEVLLKVMDARHQNCMESFLEAASLMSQVSYPHLVLLHGVCMAGDSIMVQEFVY LGAIDMYLRKCGHLVPASWKLQVIKQLAYALNYLEDKGLPHGNVSARKVLLAREGMDGSP PFIKLSDPGVSPTVLSLEMLTDRIPWVAPECLQEARTLGLEADKWGFGATVWEVFSGGPM HITSLEPAKKLKFYEDQGQLPAPKWTELAGLITQCMAYDRGQRPSFRAILRDLNGLITSD YELLSDPTPGSLSPRDELCSGAQLYACQDPTIFEERHLKYISLLGKGNFGSVELCRYDPL GDNTGPLVAVKQLQHSGPDQQRDFQREIQILKALHSDFIVKYRGVSYGPGRQTLRLVMEY LPSGCLRDFLQRHRARLHTGRLLLFAWQICKGMEYLGARRCVHRDLAARNILVESEAHVK IADFGLAKLLPLGKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSFGVVLYELFTYS DKSCSPSAEFLRMLGPERDGPALCRLLELLTEGCRLPPPPSCPIEVQELMQLCWAPSPQD RPAFSALSPQLDALWRGSPG NT seq 3303 nt NT seq  +upstreamnt  +downstreamnt atggcacctccaagtgaagagacacctctgatccctcagcgctcttgcagcctgtcatcc tcagaggcaggatccctgcatgtcctccttcctccccggggatctgggcctccccggaga ctgtcattctcctttggggactacttggcagaggatctgtgtgtgcaggcagccaaagcc tgtggcatcctgcctgtttatcatccgctctttgctctggccaccgaggacttgtcttgc tggttccccccaagccacatcttctccatggaggacatggacactcaagtcttggtctac aggctccgcttttatttccctgactggtttgggctggagacatgtcaccgctttgggcgg cgcaaagatttgaccagcgccattctcgacttacatgttttagaacacctctttgcccag catcgcagtgacttgctgagtggacgcctgtcagtgggcctcagcctgaaggagcaggga gaatgcctgagcctggccgttttagacctggctcagatggctcgtgagcaggcccagcgg ccaggtgagctgctgaagacagtcagttacaaggcctgcctgccacctggcctgcgcgac ctgatccagagtatgagcttcgtgacgcgcagacgcatccgcaggaccgtgctccaggct ctgcgtcgcgtggttgcctgccaggccgaccgctactctctcatggccaagtatatcctg gacctggagcggctgcacccagctgccaccgccgaaaccttccgcgtgggactcccgagt gcccaggagggagcagcgctcctgcgcgtgactgggggcagcggcatcgcctggagctcc ggggaccaggagtttttccagaccttctgtgactttcccgaaatcgtggatgtcagcatt aagcaggccccacgcgtgggtccagctggggagcaccggctggtcaccgtcaccaggatg gatagccacatcctggaagcagagttcccagggctgcccgaggcgctgtccttcctggcc ctcgtagatggttacttccgcctggtctgcgactccaggcacttcttctgcaaagaggtg gcgccgccaaggctgctggaggaagtggcagagctgtgccatggacccatcacgttagac ttcgccatctacaagctgaaggccgctggctcgctcccaggctcctacattctccgccgc agccctcaggactatgacagttttcttctcactgcctgcgtccagacgccccttggtccg gattacaagggctgcctcatccgccaggaccccacaggggccttctccctggttgggctc agccagccacaccgaagcctccgggagctccttgcatcttgctggcattctgggctgcat gtagatggtgctgccctgaacctcacattctgctgcacccccagacccaaggaaaagtcc aatttgatcatagtgagaaggggctgcaccccttccccaccccctggccgtgccccgtcc tgctgtgcgctgacccagctgaccttccacacaatctctgctgacagcctggagtggcat gagaacctgggccacggctctttcaccaagatataccggggccgtctgctggaggtcgtg gatggtgagacacatgacacagaagtcctcttgaaggtcatggatgccaggcaccaaaac tgcatggagtcctttctcgaagctgccagcttgatgagccaagtatcctacccgcacctg gtgttgctgcatggcgtctgcatggctggagacagcatcatggtgcaggaatttgtctac ctaggagcaattgacatgtaccttcgaaagtgtggccacctggtgccagccagctggaag ctgcaagtgatcaaacagctagcctatgccctcaactatttggaggacaaaggcctccct catggcaacgtgtcagcgcggaaagtgctcctggctcgtgaggggatggatgggagtcca cctttcatcaagctgagtgaccctggcgtcagccctacggtgctgagcctagaaatgctc accgacaggatcccctgggtggcccccgagtgtctgcaggaagcccggaccctgggcttg gaagctgacaagtggggcttcggcgccaccgtgtgggaggttttcagcggaggacccatg cacatcacttctctggagcctgccaagaaactgaagttttacgaggaccaggggcagcta ccggcccccaagtggaccgagctggcggggctcatcactcagtgcatggcgtatgaccgc ggccagcggccctccttccgtgccatcctcagggacctcaacggcctcattacgtcagat tatgagctcctctcagacccgacaccgggcagcctgagtccccgagatgagctgtgcagt ggcgcccaactctatgcctgccaggaccccaccatctttgaggaaaggcaccttaagtac atctctctgctgggcaagggcaactttggcagcgtggagctgtgccgctatgaccctctg ggggacaatacaggacccctggtggcggtgaaacagctacagcacagcgggccagaccag cagagggacttccagcgggagattcagatcctcaaggcgctgcacagcgacttcatcgtc aagtaccggggagtcagctacggtccgggtcgccagacccttcggctggttatggagtac ctacccagcggctgcctacgggatttcctgcagcgtcaccgcgcacgcctgcacaccggc cgcctgctgctgtttgcctggcagatctgcaagggcatggaatacctgggcgcgcgccgc tgcgtgcaccgcgacctggctgcgcgaaacatcctggttgagagcgaggcgcatgttaag atcgcggacttcggcctcgctaagctgctaccgctcggaaaggactattacgtggtccgc gagccgggccagagccccatcttctggtacgccccagaatccttgtctgacaacatcttc tcccgccaatctgacgtgtggagcttcggcgtggtgctgtacgagctcttcacctacagc gataagagctgcagcccatccgccgagttcctgcgcatgttagggccggagcgagatggg cctgctctctgccgcctcctggagctgctgactgagggctgccgcctcccgccacctcct tcttgccccatagaggttcaggagcttatgcagctgtgctgggctcccagcccgcaagac cggccggccttcagcgccctgagtccacagctggacgcgctgtggcgtggaagccctgga tag

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