Phodopus roborovskii (desert hamster): 127223966
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Entry
127223966 CDS
T08852
Symbol
Hsd11b1
Name
(RefSeq) 11-beta-hydroxysteroid dehydrogenase 1
KO
K15680
corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:
1.1.1.146
]
Organism
prob
Phodopus roborovskii (desert hamster)
Pathway
prob00140
Steroid hormone biosynthesis
prob00980
Metabolism of xenobiotics by cytochrome P450
prob01100
Metabolic pathways
prob05204
Chemical carcinogenesis - DNA adducts
Module
prob_M00109
C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:
prob00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
127223966 (Hsd11b1)
09111 Xenobiotics biodegradation and metabolism
00980 Metabolism of xenobiotics by cytochrome P450
127223966 (Hsd11b1)
09160 Human Diseases
09161 Cancer: overview
05204 Chemical carcinogenesis - DNA adducts
127223966 (Hsd11b1)
Enzymes [BR:
prob01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.146 11beta-hydroxysteroid dehydrogenase
127223966 (Hsd11b1)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
adh_short
adh_short_C2
KR
DUF1776
THF_DHG_CYH_C
2-Hacid_dh_C
Motif
Other DBs
NCBI-GeneID:
127223966
NCBI-ProteinID:
XP_051042640
LinkDB
All DBs
Position
Unknown
AA seq
291 aa
AA seq
DB search
MAFMKKYLLPILVLFLAYYYSTKEEFRPEMLQGKKVIVTGASKGIGREMAYHLSEMGAHL
VLTARSEEGLQKVVSRCLELGAASAQYIAGTMEDMTFAEQFVLKAGKLMGGLDMLILNHI
TYTPMGFFHDDIHALRKAMEVNFISYVVMSVAALPMLKQNNGSIVVVSSMAGKMSHPLVA
PYSASKFALDGFFSSIRKEYGVTKVNVSITLCVLGLINTETALKATSGVFSAQASPKEEC
ALEIIKGAALRKDEVYYDSWSWTPILLANPGRKIMEFLSIKNFVFDKLVSS
NT seq
876 nt
NT seq
+upstream
nt +downstream
nt
atggcgtttatgaaaaaatacctcctccccattctggtgctcttcttggcctactactat
tctacaaaagaagagttcagaccagaaatgctccaagggaagaaagtgattgtcactggg
gccagcaaagggatcggaagagaaatggcgtatcatctgtcagaaatgggagcccatttg
gtattgactgcgaggtcagaggaaggtctccagaaggtggtatcccgctgccttgaactc
ggagcagcctctgctcagtacattgctggcaccatggaagatatgacatttgcagagcaa
tttgttctcaaagcaggaaagctcatgggcggcctggacatgctcattctcaaccacatc
acttatacccctatgggtttcttccatgatgatatccatgctttgcgcaaagccatggag
gtcaacttcatcagctacgtagttatgagtgtggctgccttgcccatgctgaagcagaac
aatggcagcattgtcgtcgtgtcttccatggctgggaaaatgtcccatcctctggttgct
ccctactctgcaagcaagtttgctctggatgggttcttctcttccattagaaaagaatat
ggagtaaccaaggtcaatgtgtccatcactctctgtgttcttggcctcataaacacagaa
acagccctgaaggcaacctctggggtgttctctgcccaagcctctcccaaggaggaatgt
gccctggagatcatcaaaggtgcggctctgagaaaagatgaggtgtactacgatagctgg
agctggacccctatcctcctggcgaacccaggaaggaagatcatggaatttctttcaata
aagaactttgtatttgacaaattagtcagcagctag
DBGET
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