Phodopus roborovskii (desert hamster): 127226337 Help Entry 127226337         CDS       T08852                                  Symbol Casp8 Name (RefSeq) caspase-8   KO K04398   caspase 8 [EC:3.4.22.61] Organism prob  Phodopus roborovskii (desert hamster) Pathway prob01524   Platinum drug resistance prob04115   p53 signaling pathway prob04210   Apoptosis prob04215   Apoptosis - multiple species prob04217   Necroptosis prob04620   Toll-like receptor signaling pathway prob04621   NOD-like receptor signaling pathway prob04622   RIG-I-like receptor signaling pathway prob04623   Cytosolic DNA-sensing pathway prob04625   C-type lectin receptor signaling pathway prob04657   IL-17 signaling pathway prob04668   TNF signaling pathway prob04932   Non-alcoholic fatty liver disease prob04936   Alcoholic liver disease prob05010   Alzheimer disease prob05016   Huntington disease prob05022   Pathways of neurodegeneration - multiple diseases prob05132   Salmonella infection prob05134   Legionellosis prob05142   Chagas disease prob05145   Toxoplasmosis prob05152   Tuberculosis prob05160   Hepatitis C prob05161   Hepatitis B prob05162   Measles prob05163   Human cytomegalovirus infection prob05164   Influenza A prob05165   Human papillomavirus infection prob05167   Kaposi sarcoma-associated herpesvirus infection prob05168   Herpes simplex virus 1 infection prob05169   Epstein-Barr virus infection prob05170   Human immunodeficiency virus 1 infection prob05200   Pathways in cancer prob05203   Viral carcinogenesis prob05416   Viral myocarditis prob05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:prob00001]  09130 Environmental Information Processing   09132 Signal transduction    04668 TNF signaling pathway     127226337 (Casp8)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     127226337 (Casp8)    04215 Apoptosis - multiple species     127226337 (Casp8)    04217 Necroptosis     127226337 (Casp8)    04115 p53 signaling pathway     127226337 (Casp8)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     127226337 (Casp8)    04621 NOD-like receptor signaling pathway     127226337 (Casp8)    04622 RIG-I-like receptor signaling pathway     127226337 (Casp8)    04623 Cytosolic DNA-sensing pathway     127226337 (Casp8)    04625 C-type lectin receptor signaling pathway     127226337 (Casp8)    04657 IL-17 signaling pathway     127226337 (Casp8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     127226337 (Casp8)    05203 Viral carcinogenesis     127226337 (Casp8)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     127226337 (Casp8)    05161 Hepatitis B     127226337 (Casp8)    05160 Hepatitis C     127226337 (Casp8)    05164 Influenza A     127226337 (Casp8)    05162 Measles     127226337 (Casp8)    05168 Herpes simplex virus 1 infection     127226337 (Casp8)    05163 Human cytomegalovirus infection     127226337 (Casp8)    05167 Kaposi sarcoma-associated herpesvirus infection     127226337 (Casp8)    05169 Epstein-Barr virus infection     127226337 (Casp8)    05165 Human papillomavirus infection     127226337 (Casp8)   09171 Infectious disease: bacterial    05132 Salmonella infection     127226337 (Casp8)    05134 Legionellosis     127226337 (Casp8)    05152 Tuberculosis     127226337 (Casp8)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     127226337 (Casp8)    05142 Chagas disease     127226337 (Casp8)   09164 Neurodegenerative disease    05010 Alzheimer disease     127226337 (Casp8)    05016 Huntington disease     127226337 (Casp8)    05022 Pathways of neurodegeneration - multiple diseases     127226337 (Casp8)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     127226337 (Casp8)    05416 Viral myocarditis     127226337 (Casp8)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     127226337 (Casp8)    04932 Non-alcoholic fatty liver disease     127226337 (Casp8)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     127226337 (Casp8)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:prob01002]     127226337 (Casp8) Enzymes [BR:prob01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.61  caspase-8      127226337 (Casp8) Peptidases and inhibitors [BR:prob01002]  Cysteine peptidases   Family C14: caspase family    127226337 (Casp8) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Peptidase_C14 DED PYRIN Motif Other DBs NCBI-GeneID:  127226337 NCBI-ProteinID:  XP_051046228 UniProt:  A0AAU9ZGH4 LinkDB All DBs Position Unknown AA seq 482 aa AA seqDB search MDFRNCLYKIAECLVSDELAALKFLCLDHIAHKKQEPINDALVLFEVLQEKGLLEEGNLS FLKELLFLIKRLDLLANFLNSSKEEMVRELQVLDKAQVSPYRVMLFQLSEDVSTMELKSF KFFLNKEIPKCKLNDDNSSLLDIFVEMEKRLLLTENNLDILKLICEQVNKSLLEKIEGYE NSSRERRMSLEARTDSPVSFLDGESHFRMQEMWDSLQEQCSHSQVSDRIYQMKSKPRGYC LIFNNNDFSKARKDIPKLHKMKDRKGTNYDEEALTETFKELHFEVVPYRDCTASKIHDVL GSYQSMDHKNKDCFVCCILSHGDKGIIYGTDGKEASIYELTSYFTGSKCPSLAGKPKIFF IQACQGDNYQKAVLVETDLEEKDSFLDVDSSQKNYIPDEADFLLGMATVKNCVSYRDPTQ GTWYIQSLCQSLRERCPQGDDILSILTGVNYDVSNKDDRKNMGKQMPQPTFTLRKKLFFP PN NT seq 1449 nt NT seq  +upstreamnt  +downstreamnt atggatttcagaaactgtctttacaagattgctgaatgcctggtcagtgatgaactggct gccctcaagtttctgtgcttggaccacatcgcacacaagaagcaggaacccatcaacgac gccctggtactatttgaggtactacaggaaaagggactgttggaggaaggcaatctgtcc ttcctgaaggaactgcttttcctcatcaaacggctggacctgctggccaacttcctgaac agcagcaaggaggagatggtgagggagctgcaggttctagacaaagcccaggtttctcct tacagggtcatgctttttcagctctcagaagatgtaagcacgatggaattgaagtctttt aagttttttttgaataaagagatccccaaatgtaagctgaatgacgataactcgagcctg cttgatattttcgtggaaatggaaaagaggctccttctgacagaaaacaacttggacatc ctgaagttgatctgtgaacaggtcaacaagagcctgctggagaagattgagggttatgaa aattcaagcagagagagaagaatgagcctcgaagcaaggacagattcaccagtttcattt ttagatggggagagtcacttcagaatgcaggaaatgtgggactccctacaagaacaatgt agccactcacaggtatcagacagaatttaccaaatgaagagcaaacctcgaggatactgt ctgatcttcaacaataatgatttcagcaaggcgcggaaggacatacccaaactccacaaa atgaaggacaggaaaggaacaaactatgatgaagaggcgttgactgagacctttaaagag cttcattttgaggttgtgccttacagagactgcacggccagtaagatccatgacgttcta ggatcctaccaaagcatggaccacaagaacaaagactgcttcgtctgctgcatcctgtcc cacggagacaagggcatcatctacggcactgatgggaaggaagcctccatctatgaactg acatcttatttcactggttcaaagtgcccttccctggctggaaaacccaaaatctttttt attcaggcttgtcagggggataactaccagaaggctgtacttgttgagactgacttggaa gagaaggacagcttcttagatgtggactcatctcaaaagaactatattccagatgaggct gactttctgctgggaatggctactgtgaaaaactgcgtatcctaccgagatcccacacag ggaacttggtacatccagtcactttgccagagcctgagggaaagatgtcctcaaggcgac gatattctcagcatcctgactggtgtgaactatgatgtgagcaataaagacgacaggaag aacatggggaaacagatgcctcagcccaccttcacactacggaagaagttgttcttccct cctaactga

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