Phodopus roborovskii (desert hamster): 127233912 Help Entry 127233912         CDS       T08852                                  Symbol Adcy1 Name (RefSeq) adenylate cyclase type 1   KO K08041   adenylate cyclase 1 [EC:4.6.1.1] Organism prob  Phodopus roborovskii (desert hamster) Pathway prob00230   Purine metabolism prob01100   Metabolic pathways prob01522   Endocrine resistance prob04015   Rap1 signaling pathway prob04020   Calcium signaling pathway prob04022   cGMP-PKG signaling pathway prob04024   cAMP signaling pathway prob04062   Chemokine signaling pathway prob04072   Phospholipase D signaling pathway prob04081   Hormone signaling prob04082   Neuroactive ligand signaling prob04114   Oocyte meiosis prob04211   Longevity regulating pathway prob04213   Longevity regulating pathway - multiple species prob04261   Adrenergic signaling in cardiomyocytes prob04270   Vascular smooth muscle contraction prob04371   Apelin signaling pathway prob04540   Gap junction prob04611   Platelet activation prob04713   Circadian entrainment prob04714   Thermogenesis prob04720   Long-term potentiation prob04723   Retrograde endocannabinoid signaling prob04724   Glutamatergic synapse prob04725   Cholinergic synapse prob04727   GABAergic synapse prob04750   Inflammatory mediator regulation of TRP channels prob04911   Insulin secretion prob04912   GnRH signaling pathway prob04913   Ovarian steroidogenesis prob04914   Progesterone-mediated oocyte maturation prob04915   Estrogen signaling pathway prob04916   Melanogenesis prob04918   Thyroid hormone synthesis prob04921   Oxytocin signaling pathway prob04923   Regulation of lipolysis in adipocytes prob04925   Aldosterone synthesis and secretion prob04926   Relaxin signaling pathway prob04927   Cortisol synthesis and secretion prob04928   Parathyroid hormone synthesis, secretion and action prob04934   Cushing syndrome prob04935   Growth hormone synthesis, secretion and action prob04970   Salivary secretion prob04971   Gastric acid secretion prob04972   Pancreatic secretion prob04976   Bile secretion prob05032   Morphine addiction prob05142   Chagas disease prob05146   Amoebiasis prob05163   Human cytomegalovirus infection prob05166   Human T-cell leukemia virus 1 infection prob05200   Pathways in cancer prob05207   Chemical carcinogenesis - receptor activation prob05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:prob00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     127233912 (Adcy1)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     127233912 (Adcy1)    04371 Apelin signaling pathway     127233912 (Adcy1)    04020 Calcium signaling pathway     127233912 (Adcy1)    04072 Phospholipase D signaling pathway     127233912 (Adcy1)    04024 cAMP signaling pathway     127233912 (Adcy1)    04022 cGMP-PKG signaling pathway     127233912 (Adcy1)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     127233912 (Adcy1)    04081 Hormone signaling     127233912 (Adcy1)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     127233912 (Adcy1)   09144 Cellular community - eukaryotes    04540 Gap junction     127233912 (Adcy1)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     127233912 (Adcy1)    04062 Chemokine signaling pathway     127233912 (Adcy1)   09152 Endocrine system    04911 Insulin secretion     127233912 (Adcy1)    04923 Regulation of lipolysis in adipocytes     127233912 (Adcy1)    04912 GnRH signaling pathway     127233912 (Adcy1)    04913 Ovarian steroidogenesis     127233912 (Adcy1)    04915 Estrogen signaling pathway     127233912 (Adcy1)    04914 Progesterone-mediated oocyte maturation     127233912 (Adcy1)    04921 Oxytocin signaling pathway     127233912 (Adcy1)    04926 Relaxin signaling pathway     127233912 (Adcy1)    04935 Growth hormone synthesis, secretion and action     127233912 (Adcy1)    04918 Thyroid hormone synthesis     127233912 (Adcy1)    04928 Parathyroid hormone synthesis, secretion and action     127233912 (Adcy1)    04916 Melanogenesis     127233912 (Adcy1)    04925 Aldosterone synthesis and secretion     127233912 (Adcy1)    04927 Cortisol synthesis and secretion     127233912 (Adcy1)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     127233912 (Adcy1)    04270 Vascular smooth muscle contraction     127233912 (Adcy1)   09154 Digestive system    04970 Salivary secretion     127233912 (Adcy1)    04971 Gastric acid secretion     127233912 (Adcy1)    04972 Pancreatic secretion     127233912 (Adcy1)    04976 Bile secretion     127233912 (Adcy1)   09156 Nervous system    04724 Glutamatergic synapse     127233912 (Adcy1)    04727 GABAergic synapse     127233912 (Adcy1)    04725 Cholinergic synapse     127233912 (Adcy1)    04720 Long-term potentiation     127233912 (Adcy1)    04723 Retrograde endocannabinoid signaling     127233912 (Adcy1)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     127233912 (Adcy1)   09149 Aging    04211 Longevity regulating pathway     127233912 (Adcy1)    04213 Longevity regulating pathway - multiple species     127233912 (Adcy1)   09159 Environmental adaptation    04713 Circadian entrainment     127233912 (Adcy1)    04714 Thermogenesis     127233912 (Adcy1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     127233912 (Adcy1)    05207 Chemical carcinogenesis - receptor activation     127233912 (Adcy1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     127233912 (Adcy1)    05163 Human cytomegalovirus infection     127233912 (Adcy1)   09174 Infectious disease: parasitic    05146 Amoebiasis     127233912 (Adcy1)    05142 Chagas disease     127233912 (Adcy1)   09165 Substance dependence    05032 Morphine addiction     127233912 (Adcy1)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     127233912 (Adcy1)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     127233912 (Adcy1)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     127233912 (Adcy1) Enzymes [BR:prob01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      127233912 (Adcy1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N Adcy_cons_dom DUF6594 Motif Other DBs NCBI-GeneID:  127233912 NCBI-ProteinID:  XP_051056533 LinkDB All DBs Position Unknown AA seq 1118 aa AA seqDB search MAGAPRGQGGGGGAGEPGGAERAAGPGGRRGLRACGEEFACPELEALFRGYTLRLEQAAT LKALAVLSLLAGSLALAELLGAPGPAPGIAKGSHPVHCILFLALFVVTNVRSLQVPQLQQ VGQLALFFSLTFALLCCPFALGGPARGSVGGAVGSAVAEQGVWQLLLVTFVSYALLPVRS LLAIGFGLVVAASHLLVTAALVPAKRPRLWRTLGANALLFVGVNMYGVFVRILTERSQRK AFLQARSCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYIQRHDN VSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYCVSGLT QPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDVWSN DVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPGHGHERNTFLRTHNIETFFIVPSHR RKIFPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFSNVMTCEDDDKRRALRT ASEKLRNRSSFSTNVVYTTPGTRVNRYISRLLEARQTELEMADLNFFTLKYKHVEREQKY HQLQDEYFTSAVVLALILAALFGLVYLLIIPQSVAVLLLLVFSICFLVACILYLHITRVQ CFPGCLTIQIRTVLCIFIVILIYSVAQGCVVGCLPWAWSSQSNSSLVVLAAGGRRTVLPA LPCESAHHALLCCLVGTLPLAIFLRVSSLPKMILLSGLTTSYILVLELSGYTRVGGGALS GRSYEPIMAILLFSCTLALHARQVDVRLRLDYLWAAQAEEERDDMERVKLDNKRILFNLL PAHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFNDFYIELDGNNMGVECLRLLNEII ADFDELMDKDFYKDLEKIKTIGSTYMAAVGLAPTAGARAKKSISSHLSTLADFAIDMFEV LDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGRIQVT EEVHRLLKRCSYQFVCRGKVSVKGKGEMLTYFLEGRTDGNSSHGRSFRLERRMCPYGRGG GQARRPPLCPAAGPLIRPGLPPAPTSQYLPPTAAGKEA NT seq 3357 nt NT seq  +upstreamnt  +downstreamnt atggcgggggcgccgcgcggccaaggcggcggcggaggcgcgggcgagcccgggggcgca gagcgggcggccgggccgggcggtcggcgcgggctccgggcgtgtggcgaggagttcgcg tgccccgagctggaggcgctgttccgcggctacacgctgcggctggagcaagcggccacg ctgaaggcgctggcggtgcttagcctgttggcgggttccctggcgctggccgaactgctg ggcgcgccgggacccgcgcccggcatcgccaagggatctcacccggtgcactgcatcctc ttcctggcactgttcgtggtcaccaatgtccgatccctgcaggtgccccagctgcagcag gtcggtcagctggcgctgttcttcagcctcaccttcgcgctactctgctgccccttcgcg ctgggtggcccggcgaggggctccgttggaggcgcagtgggatccgcggttgctgagcag ggggtttggcaactccttttggtcaccttcgtgtcctatgccttgctgcccgtgcgcagc ctactggccatcggcttcgggctggtggtggctgcctctcacttactggtcacagccgcc ttggtccctgccaagcgcccacgtctctggaggacgcttggtgccaatgccctgctcttc gtgggagtgaacatgtatggcgtcttcgtgcggatcttgacagagcgctcacagaggaag gcctttttgcaggcccgaagctgcattgaggaccggctgcggctggaggatgagaacgag aagcaggagcggttgctcatgagcctcttgccccggaatgtcgccatggagatgaaggaa gatttcctgaagccccctgagaggattttccacaagatttacatccagaggcatgataac gtgagcatcctgtttgcagacatcgtgggtttcacaggtctggcatcccagtgcacggct caggagctggtgaaactgctcaatgaactctttggcaagtttgacgagttagccacggag aaccactgtcgccgcatcaagatcctgggggactgctactactgtgtgtcgggcctcacc cagcccaagacggaccacgcccattgctgtgtagagatggggcttgacatgatcgatacc atcacatccgtggctgaggctactgaagtagacctgaacatgcgtgtggggctacacacc ggcagggtcctctgtggtgtcctgggcctacgcaagtggcagtacgatgtatggtccaat gacgtgaccctggccaatgtcatggaggctgctggcttacctgggaaagttcacatcaca aaaacaaccctcgcgtgcttgaatggggactacgaagtggagccaggtcatggccatgag aggaacaccttcctgagaactcacaacatcgagaccttcttcattgtaccatcccatcgg agaaagatatttccaggcttgattctctccgatataaaaccagccaagaggatgaagttc aagactgtctgctacctgcttgtgcagctcatgcactgccggaaaatgttcaaagccgag atccctttctccaacgtaatgacctgtgaggatgacgacaagcggagggcattgagaaca gcctcggagaagctcagaaaccgctcatctttctctaccaatgtggtctacaccactccg ggcacacgtgtcaacaggtacatcagccgtcttcttgaagcccgccagacagagctggag atggcagatctgaacttctttaccctgaagtacaagcatgtcgaacgggagcaaaaatac caccagcttcaggatgagtacttcaccagcgctgttgtcctcgccctcatcctggctgcc ttatttgggcttgtctaccttctgataattccacagagtgtggctgtcctgctgctgctg gtgttttctatctgcttcttggtggcctgtatcctgtacctgcacatcacgcgggtccag tgttttccagggtgcctgacgatccagattcgcactgtgttgtgtatattcatagtgatc ttaatctactcagtagctcaaggatgtgtggtgggctgcctgccctgggcctggagctct cagtccaacagctccctagtggtccttgcagccggaggccggcgcactgtgctgcctgct ctgccctgtgagtctgcgcaccatgccctgctctgctgcctggtgggcaccctcccacta gccatattcctgcgggtgtcctccttgccaaagatgatcctgctgtctgggctgaccaca tcctacatcctcgttctggaactcagtggctataccagggttgggggcggtgccctctct gggcgcagctatgaaccaatcatggctatcctgctgttctcatgcacactggccctgcac gccaggcaagtggatgtcagactgcggctggactacctctgggcagcacaggcagaggag gagagggatgacatggagagagtgaagctggacaacaagaggatcctcttcaacctcctg ccagcccacgtcgcacagcacttcctcatgtccaatccgaggaacatggacctgtattac cagtcctactcccaggtgggcgtcatgttcgcctccatccccaacttcaatgacttctac atcgagctggatggcaacaacatgggggttgagtgtctacggctcctcaatgagatcatt gctgactttgatgagctcatggacaaggacttttacaaggacctggagaagattaagacc attgggagtacgtatatggccgccgtggggctggcgcccacagcaggagccagggctaag aagtcaatctcttcccacctgagcacactggcagactttgccatcgatatgtttgaagtc ctggatgaaatcaactaccagtcctacaacgactttgttctccgagtcggcatcaacgtt ggccctgtggtggctggagtgattggcgctcgcaggccccaatacgacatctggggaaac acagtcaatgtggccagtcgaatggacagcactggagtccagggaagaatccaggtgact gaggaggtccaccggttgctgaagaggtgctcataccagtttgtgtgcagaggcaaagtc agcgtcaagggcaagggagagatgctaacatactttctagaaggcaggactgatggaaac agttcccatggcaggtcttttcgcttggagcggagaatgtgtccttatgggagaggtgga ggccaggccagacggcccccactgtgtcctgcagctggacccctgatcaggccggggctc cccccagcccccactagccagtacctgccacccacagcagcagggaaggaagcctag

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