Promicromonospora sp. MS192: ACO229_16870
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Entry
ACO229_16870 CDS
T11467
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
proz Promicromonospora sp. MS192
Pathway
proz00020
Citrate cycle (TCA cycle)
proz00630
Glyoxylate and dicarboxylate metabolism
proz00785
Lipoic acid metabolism
proz01100
Metabolic pathways
proz01110
Biosynthesis of secondary metabolites
proz01120
Microbial metabolism in diverse environments
proz01200
Carbon metabolism
proz01210
2-Oxocarboxylic acid metabolism
Module
proz_M00009
Citrate cycle (TCA cycle, Krebs cycle)
proz_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
proz00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
ACO229_16870
00630 Glyoxylate and dicarboxylate metabolism
ACO229_16870
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
ACO229_16870
Enzymes [BR:
proz01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
ACO229_16870
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
ACO229_16870
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
ACO229_16870
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
ACO229_16870
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NCBI-ProteinID:
XRE12859
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Position
3748836..3752624
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AA seq
1262 aa
AA seq
DB search
MSPKAGSESISVASSSFGANEWLVDELYQQYLKDKNAVDPAWWDFFADYTPGENGSAKDG
GPAAPTATPEAAPAAPAEAAPAPAAPAQQAPVTGGTAASEAGQPVREKVLPADPKINPAN
PIATPPTTHYADTFERPVAHPDAVDDVQKLRGPAARVVTNMEASLEVPTATSVRAVPAKL
MVDNRIVINNHLKRGRGGKISFTHLIGFALVEALADMPVMNAHYEQVDGKPGVNQPAHVG
FGLAIDLAKPDGSRQLLVPSIKKAEELDFAEFWAAYEELVRKARGGKLGVPDFQGTTISL
TNPGGIGTVHSVPRLMQGQGTIVGVGAMDYPAEFAGASEEQLARMGVSKVMTLTSTYDHR
IIQGAQSGEFLKIIAEKLLGLDGFYDRVFAALRVPYEPVRWVRDNTVDADVEAAKPAKIA
EVVQAYRSRGHLMADTDPLAYRQRKHPDLDIQNHGLTLWDLDRTFPTAGFGTKPKATLRE
ILGLLRDSYCRTIGIEYMHIADPAQRKWLQERLEAGYAKTPREDQLRILRRLNSAEAFET
FLQTKFVGQKRFSLEGGESLIPLLDAILSKAAEGGLDEVGIGMAHRGRLNVLANIAGKSY
GQIFKEFEGQLDPKSVQGSGDVKYHLGTEGTFTSESGATTRVYLAANPSHLEAVDPVLEG
IVRAKQDRIDLGGDGFSVLPILVHGDAAFAGQGVVPEVLNLSQLRGYRTGGTIHVVVNNQ
VGFTTGPTASRSTTYATDVAKGYQVPVMHVNGDDPEAVVRTAELAFAFREQFGQDVIIDL
ICYRRRGHNEGDDPSMTQPLMYNLIETKRSVRKLYTENLVARGDITVEEAEGALQDYQSQ
LERVFTETKSGFTPAPQTEHLAGLERPESQREDAGTMVGWQTAISQELLQRVGDVHTTPP
EGFTVHPKLAQLLEKRQLMAKEGGIDWGFGELAAFGSLLVEGTPVRLAGQDSRRGTFVQR
HAVLHDRETGAEWTPLLYLSSDQAKFWVYDSSLSEYAALGFEYGYSVERPDALVLWEAQF
GDFVNGAQTVIDEFISSAEQKWGQSSSVVMLLPHGYEGQGPDHSSARIERFLQLCAENNI
TVAQPSTPASYFHLLRRQAYARPRRPLVVFTPKQLLRLKAAASAAEDFTEGTFREVLADT
TADPAKVDRVILCTGRVYYDLLAERTKRGDEGVALVRLEQLYPFPEEQIRAELAKYGDAE
VVWVQDEPQNQGAWGFIHLALPMDVPYVKVVSRPASASTAAGTAKLHQAQQKTLLEQAFA
RG
NT seq
3789 nt
NT seq
+upstream
nt +downstream
nt
gtgtcccctaaggctggttcagagtcgatcagcgtggcgagctcgtcattcggagccaac
gagtggcttgtggacgagctctaccagcagtacctgaaggacaagaacgcggtggacccc
gcgtggtgggacttcttcgccgactacaccccgggggagaacgggtccgccaaggacggc
ggtccagcggcccccaccgcgaccccggaggccgcccccgcggcacctgccgaggccgcc
cccgcgccggcagcacccgcgcagcaggccccggtcacgggcggcaccgccgcctcggag
gccggccagcccgtgcgcgagaaggtcctcccggccgacccgaagatcaacccggcgaac
cccatcgccaccccgcccaccacgcactacgcggacacgttcgagcgcccggtggcgcac
ccggacgccgtcgacgacgtccagaagctccgcggcccggccgcgcgcgtggtcacgaac
atggaggcctctctcgaggtccccaccgccacctcggtgcgcgccgtgcccgccaagctg
atggtcgacaaccgcatcgtcatcaacaaccacctcaagcgcggccgtggcggcaagatc
tcgttcacgcacctcatcggcttcgcgctggtcgaggcgctggcggacatgcccgtcatg
aacgcccactacgagcaggtggacggcaagccgggggtgaaccagcccgcgcacgtcggc
ttcggcctcgcgatcgacctggccaagcccgacggctcgcgccagctcctggtgcccagc
atcaagaaggccgaggagctcgacttcgccgagttctgggcggcctacgaggagctggtc
cgcaaggctcgcggcggcaagctcggcgtcccggacttccagggcaccacgatctcgctg
accaacccgggcggcatcggcaccgtgcactccgtgccgcggctcatgcagggtcagggc
accatcgtcggcgtcggagccatggactacccggccgagttcgccggtgcgtccgaggag
cagctcgcccggatgggcgtctcgaaggtcatgacgctcacgtcgacctacgaccaccgc
atcatccagggcgcgcagtccggcgagttcctcaagatcatcgcggagaagctgctcgga
ctggacggcttctacgaccgcgtcttcgcggccctgcgcgtgccgtacgagcccgtccgc
tgggtgcgcgacaacacggtcgacgccgacgtcgaggccgccaagccggccaagatcgcc
gaggtcgtgcaggcgtaccgctcgcgcggtcacctcatggcggacaccgacccgctcgcc
taccgccagcgcaagcaccccgacctggacatccagaaccacggcctgacgctgtgggac
ctggaccggaccttcccgacggcaggcttcggcaccaagccgaaggccacgctgcgcgag
atcctcggcctgctgcgcgactcgtactgccgcaccatcggcatcgagtacatgcacatc
gccgacccggcgcagcgcaagtggctccaggagcgcctggaggccggctacgccaagacg
ccgcgcgaggaccagctccgcatcctgcgccgcctgaactccgccgaggcgttcgagacg
ttcctgcagaccaagttcgtcgggcagaagcgcttctcgctggagggcggcgagtccctc
atcccgctgctcgacgcgatcctgtcgaaggccgccgagggtggcctcgacgaggtcggc
atcggcatggcccaccgcggccgcctcaacgtgctggcgaacatcgcgggcaagagctac
ggccagatcttcaaggagttcgagggccagctcgacccgaagagcgtccagggctccggt
gacgtcaagtaccacctcggcaccgagggcacgttcacctcggagtccggcgccaccacg
cgcgtctaccttgcggccaacccgtcgcacctggaggccgtggacccggtgctcgagggc
atcgtgcgcgccaagcaggaccgcatcgacctcggtggcgacggcttctccgtgctgccg
atcctggtgcacggcgacgccgccttcgcgggccagggcgtggtccccgaggtgctgaac
ctgtcgcagctgcgcgggtaccgcaccggcggcaccatccacgtggtcgtcaacaaccag
gtcggcttcaccaccggcccgacggcgtcccgctcgaccacctacgcgaccgacgtggcc
aagggctaccaggtcccggtcatgcacgtgaacggcgacgaccccgaggccgtcgtgcgc
accgccgagctggccttcgcgttccgcgagcagttcggccaggacgtcatcatcgacctc
atctgctaccgccgccgcgggcacaacgagggcgacgacccgtcgatgacgcagccgctc
atgtacaacctcatcgagaccaagcgctcggtgcgcaagctctacaccgagaacctggtc
gcgcgcggtgacatcaccgtcgaggaggccgagggcgcgctgcaggactaccagtcgcag
ctcgagcgggtgttcaccgagaccaagtccgggttcacgcccgcgccgcagaccgagcac
ctcgccggcctggagcggcccgagtcccagcgtgaggacgccgggacgatggtcggctgg
cagaccgcgatctcgcaggagctgctgcagcgcgtcggcgacgtgcacaccacgcccccc
gagggcttcacggtgcaccccaagctcgcgcagctcctcgagaagcgccagctcatggcg
aaggaaggcggcatcgactggggcttcggcgagctcgcggccttcggttcgctgctcgtg
gagggcaccccggtgcgcctcgccggccaggactcgcgccgcggcacgttcgtgcagcgc
cacgcggtgctgcacgaccgcgagaccggtgccgagtggaccccgctgctgtacctgtcg
agcgaccaggccaagttctgggtctacgactcctcgctgtcggagtacgcggcgctcggc
ttcgagtacggctactccgtggagcgcccggacgccctggtgctgtgggaggcgcagttc
ggcgacttcgtcaacggcgcccagacggtgatcgacgagttcatctcgtccgccgagcag
aagtggggccagtcgtcctcggtggtcatgctgctgccgcacgggtacgagggccagggg
cctgaccactcgtcggcccgcatcgagcggttcctgcagctgtgcgccgagaacaacatc
acggtcgcgcagccgtccacgccggcgtcgtacttccacctgctgcgccgtcaggcctac
gcccggccgcgccgtccgctcgtggtgttcacgcccaagcagctcctgcgcctcaaggcg
gcggcgtccgcagcggaggacttcaccgagggcacgttccgcgaggttctcgcggacacc
accgcggacccggcgaaggtggaccgcgtgatcctgtgcaccggccgcgtgtactacgac
ctgctcgccgagcgcaccaagcgcggcgacgagggcgtggcgctcgtccgcctggagcag
ctctacccgttcccggaggagcagatccgcgcggagctcgccaagtacggcgacgccgag
gtggtctgggtccaggacgagccgcagaaccagggcgcgtggggcttcatccacctggca
ctgccgatggacgtgccgtacgtcaaggtggtctcccgcccggcgtcggcctcgacggcg
gccggtacggccaagctgcaccaggcccagcagaagaccctgctggaacaggccttcgcg
cgcggctga
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