KEGG   Pseudonocardia sp. EC080625-04: FRP1_12315
Entry
FRP1_12315        CDS       T04054                                 
Symbol
metH
Name
(GenBank) B12-dependent methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
psee  Pseudonocardia sp. EC080625-04
Pathway
psee00270  Cysteine and methionine metabolism
psee00450  Selenocompound metabolism
psee00670  One carbon pool by folate
psee01100  Metabolic pathways
psee01110  Biosynthesis of secondary metabolites
psee01230  Biosynthesis of amino acids
psee04980  Cobalamin transport and metabolism
psee04981  Folate transport and metabolism
Module
psee_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:psee00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    FRP1_12315 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    FRP1_12315 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    FRP1_12315 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    FRP1_12315 (metH)
   04980 Cobalamin transport and metabolism
    FRP1_12315 (metH)
Enzymes [BR:psee01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     FRP1_12315 (metH)
SSDB
Motif
Pfam: Met_synt_B12 S-methyl_trans Pterin_bind B12-binding_2 B12-binding
Other DBs
NCBI-ProteinID: ALE76254
LinkDB
Position
complement(2645674..2649285)
AA seq 1203 aa
MRELLGSRIGVIDGAWGTVIQGLGLTADDYKAEWLEGHHKDTNGDPDLLNLTRPDLILDS
HRRYFTAGADLTTTNTFTATTIGQADYGLEDHVVAMNVEAAKLARQAADESEAETGEPKW
VAGSIGPLNVTLSLSPKVEDPAFRAVTYQEVYQSYAEQIAALDDGGVDLLLIETIFDTLN
SKAALHAAHDIAPHLPIWISVAIVDRSGRTLSGQTVDAFWTSIRHADPLVVGLNCSLGAE
DMRPHVVALSEISDTFTASYPNAGLPNAFGGYDETPDQTAALLREFAESGLVNIVGGCCG
TGHDHIREIAGAVKDVAPRTPVEPAHRTRFSGLERFDIVPDTGFVMIGERTNVTGSKRFR
RLIESKDYNGALDVALDMVRGGANMLDVNMDADLLESDEEMTTFLNLLATEPEIARLPIM
IDSSRWSVVEAGLRCVQGKGVVNSISLKEGEEPFLRQAATVRSYGAGVVVMAFDETGQAD
TADRKVEICGRAYDLLVEKAGLPPEDIIFDPNILAIATGMEEHNDYAKDFIEALPRIKER
CPGAHISGGVSNLSFAFRGNNVVREAMDSAFLFHAIQAGLDMGIVNAGQLAVYQDIPADL
LEMVEDVLFNRRPDATDRLVESADRFKGEGTQRKVDLSWRENDVRSRISHALVHGIVDYI
EEDTEEARAEADRPLHVIEGPLMDGMKVVGDLFGDGKMFLPQVVKSARVMKRAVAYLEPY
MEEEKEEARARGEIDDRGNGKVVMATVKGDVHDIGKNIVGVVLGCNSYEVVDLGVMVPAQ
TILDTAVAENADVIGLSGLITPSLDEMVGVAAEMERRGLKLPLLIGGATTSRQHTAVKIA
PAYDGNVLHVLDASRVVGVVSDLLDDDRAEALGKRNGEDQERLREQHANREAKPLLPFEE
AVANREQVTFDDLPAPEFTGVRECAPTIAELRELIDWQFLFLAWELKGKFPGILNSPVAK
ELYDDANAMLDEIIEGDRFTAKGVYGFWPAHAEGEDIVISPDAGDVRLPMLRQQTKKPEG
RANRSLADYVAPEGDHLGAFAVSIHGAEEMAKEYEDALDDYRAIMVKALVDRLAEAFAEY
AHLQARRQWFEPGAEQPLEELLGEKFRGIRPAFGYPACPDHTQKRPLFDLLGAEELGIEL
TESYAMTPAAAVSGMMFAHPDSRYFTVGRIGRDQVTDYAGRLGTEVDEVERWLRPNLGYN
PDA
NT seq 3612 nt   +upstreamnt  +downstreamnt
ctgcgggaactcctcggcagccggatcggtgtcatcgacggtgcctggggcaccgtcatc
cagggcctgggcctcaccgccgacgactacaaggcggagtggctggagggccaccacaag
gacaccaacggcgacccggacctgctgaacctgacccgtccggacctgatcctggacagt
caccggcgctacttcacggccggcgccgacctcacgacgacgaacaccttcaccgccacc
accatcggccaggccgactacggcctcgaggaccacgtggtggcgatgaacgtcgaggcc
gcgaagctggcccggcaggcggccgacgagtcggaggcggagaccggcgagcccaagtgg
gtcgcgggctccatcgggccgctgaacgtcaccctgtcgctgtcgccgaaggtcgaggac
ccggcgttccgcgcggtgacctaccaggaggtctaccagtcctacgccgagcagatcgcg
gcgctggacgacggcggtgtggacctgctgctgatcgagacgatcttcgacacgctgaac
tcgaaggccgccctgcacgccgcgcacgacatcgcgccgcacctgccgatctggatctcg
gtggcgatcgtcgaccggtcgggccggacgctgtccgggcagaccgtggacgccttctgg
acctcgatccggcacgccgacccgctggtcgtcggcctgaactgctcgctgggcgcggag
gacatgcgcccgcacgtcgtcgcgctgtccgagatcagcgacacgttcaccgcgagctac
ccgaacgccggcctgccgaacgccttcggcggctacgacgagaccccggaccagaccgcg
gccctgctccgcgagttcgccgagtccggcctggtgaacatcgtcggcgggtgctgcggc
accgggcacgaccacatccgcgagatcgcgggcgcggtcaaggacgtggccccgcggacc
cccgtggagcccgcccaccggacccggttctccgggctcgagcggttcgacatcgtcccg
gacaccggcttcgtgatgatcggtgagcggaccaacgtcaccgggtccaagcggttccgc
aggctcatcgagtcgaaggactacaacggcgcgctcgacgtcgcgctggacatggtccgc
ggcggcgcgaacatgctggacgtcaacatggacgccgacctcctcgagtccgacgaggag
atgacgaccttcctgaacctgctggccaccgagccggagatcgcccggctgccgatcatg
atcgacagctcgcggtggtcggtcgtcgaggccgggctgcggtgcgtgcagggcaagggc
gtcgtcaactcgatcagcctgaaggagggggaggagcccttcctccgccaggccgcgacg
gtccggtcctacggggcgggcgtcgtcgtcatggcgttcgacgagacgggccaggccgac
accgccgaccggaaggtcgagatctgcggacgggcctacgacctgctggtcgagaaggcg
ggcctcccgcccgaggacatcatcttcgacccgaacatcctcgccatcgccaccggcatg
gaggagcacaacgactacgcgaaggacttcatcgaggccctcccgcggatcaaggagcgc
tgcccgggcgcgcacatctccggtggcgtctcgaacctgtcgttcgccttccgtggcaac
aacgtcgtccgcgaggcgatggactcggcgttcctgttccacgccatccaggccggcctg
gacatgggcatcgtcaacgccggccagctcgcggtctaccaggacatcccggccgacctg
ctcgagatggtcgaggacgtcctgttcaaccggcgtcccgacgccaccgaccggctcgtc
gagagcgccgaccggttcaagggcgagggcacccagcgcaaggtcgacctcagctggcgg
gagaacgacgtccgctcgcggatctcgcacgccctggtgcacggcatcgtggactacatc
gaggaggacaccgaggaggcgcgcgccgaggccgaccggccgctgcacgtcatcgagggt
ccgctcatggacggcatgaaggtcgtcggcgacctgttcggcgacggcaagatgttcctc
ccgcaggtggtgaagtcggcgcgcgtgatgaagcgggcggtcgcctacctcgagccgtac
atggaggaggagaaggaggaggccagggcccgcggggagatcgacgaccgcggcaacggc
aaggtcgtcatggccacggtcaagggcgacgtccacgacatcggcaagaacatcgtcggt
gtggtgctcggctgcaacagctacgaggtcgtcgacctcggcgtgatggtgcccgcgcag
accatcctcgacaccgccgtcgcggagaacgccgacgtcatcggcctgtcgggtctcatc
accccgtcgctggacgagatggtcggcgtcgccgcggagatggagcgccgggggctcaag
ctgccgctgctcatcggtggggcgacgacctcgcgccagcacaccgcggtgaagatcgcg
cccgcctacgacggcaacgtgctccacgtgctcgacgcctcccgcgtcgtcggggtggtc
tccgacctgctcgacgacgaccgcgcggaggccctgggcaagcgcaacggcgaggaccag
gagcggctgcgcgagcagcacgcgaaccgggaggccaagccgctgctgccgttcgaggag
gcggtggccaaccgcgagcaggtcaccttcgacgacctgcccgcgccggagttcaccggg
gtccgcgagtgcgcgccgaccatcgcggagctgcgcgagctgatcgactggcagttcctg
ttcctggcctgggagctcaagggcaagttccccgggatcctgaactcgccggtggccaag
gagctctacgacgacgccaacgcgatgctcgacgagatcatcgagggcgaccgcttcacg
gcgaagggcgtctacgggttctggcccgcgcacgccgagggcgaggacatcgtcatctcg
ccggacgcgggtgacgtccggctgccgatgctgcgccagcagaccaagaagccggagggc
cgcgccaaccgcagcctcgccgactacgtggcgcccgagggcgaccacctcggcgccttc
gcggtctccatccacggtgcggaggagatggccaaggagtacgaggacgccctcgacgac
taccgggccatcatggtgaaggcgctggtcgaccggctcgcggaggcgttcgccgagtac
gcgcacctccaggcacgccggcagtggttcgagcccggtgccgagcagccgctcgaggag
ctcctcggcgagaagttccgcgggatccgtccggcgttcggctacccggcctgcccggac
cacacccagaagcgtccgctgttcgacctgctcggcgcggaggagctgggcatcgagctg
accgagtcgtacgcgatgaccccggcggccgccgtcagcggcatgatgttcgcccatccc
gactcccggtacttcaccgtgggccggatcgggcgcgaccaggtcaccgactacgcgggc
cggctcggcaccgaggtcgacgaggtcgagcggtggctgcggcccaacctcgggtacaac
cccgatgcctga

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