Polypterus senegalus (gray bichir): 120522925
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Entry
120522925 CDS
T08668
Symbol
hsd3b1
Name
(RefSeq) hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 isoform X1
KO
K00070
3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:
1.1.1.145
5.3.3.1
]
Organism
psex
Polypterus senegalus (gray bichir)
Pathway
psex00140
Steroid hormone biosynthesis
psex01100
Metabolic pathways
Module
psex_M00107
Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
psex_M00110
C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
psex_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
psex00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
120522925 (hsd3b1)
Enzymes [BR:
psex01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
120522925 (hsd3b1)
5. Isomerases
5.3 Intramolecular oxidoreductases
5.3.3 Transposing C=C bonds
5.3.3.1 steroid Delta-isomerase
120522925 (hsd3b1)
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Gene cluster
GFIT
Motif
Pfam:
3Beta_HSD
Epimerase
NAD_binding_4
Polysacc_synt_2
GDP_Man_Dehyd
KR
NAD_binding_10
RmlD_sub_bind
Sacchrp_dh_NADP
NmrA
Ldh_1_N
adh_short
Motif
Other DBs
NCBI-GeneID:
120522925
NCBI-ProteinID:
XP_039599650
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Position
2:complement(54118979..54142715)
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AA seq
378 aa
AA seq
DB search
MSLIGDVCLITGACGFLGQKIIQLLIEENELAEIRLLDLNINPKLIESLEAIRGQTKITK
LEGDIRDIELLKKACQDVSLVIHTASVIDILGAVDKNEMTAVNVTGTQLLLETCLQKNVK
YFIYTSSLEVAGPNKMGDSIINGNEDTPPYSCCLKFTYSITKQKAEQITLQTNGKHLHNG
EQIVTCSLRPTYIYGEGSKFILQHFDTAIRNGNVLKRTSKKEALVNPVYVGNVAWAHILS
AKAMKDLHKVKQIGGHFFFISDDTPHMSYSDFNDVLLKPLGIIVPEKLELPMPLLFFLAF
LMEMLQFLLKPFVKYTPSMNRQLLIMLNTHFTFTYAKAQKAFGYTPRYRWTEAKTTTSEW
LSSVLSERCELVKKMKTH
NT seq
1137 nt
NT seq
+upstream
nt +downstream
nt
atgtctctcatcggagatgtttgcctaattacgggggcctgtggtttcttgggacaaaaa
atcatacaacttctgattgaggagaatgaactagcagaaatccgactgcttgacttgaac
attaatccaaaattgatagagtccttagaagcaattcgaggtcagacaaagatcaccaag
cttgagggggacatcagagacattgaattactgaagaaagcttgccaggatgtttccctt
gttattcatacagcttcagtcatcgatatattgggggcggtggacaaaaatgaaatgact
gctgttaatgtgacaggtacccagttgcttctggaaacatgccttcagaagaatgtaaag
tacttcatctacacaagcagccttgaggtggctggtccaaacaaaatgggggatagcatc
attaatggaaatgaagacaccccaccctactcatgctgcttaaagtttacatacagcatc
acaaagcaaaaagctgaacaaataacactgcaaacaaatggcaaacatctccacaacggt
gagcagattgtcacttgctccctgagacccacatatatttatggagaagggagtaaattc
attctgcaacattttgatacagccattagaaatggcaatgttctcaaacgaacctccaaa
aaggaagctttggtaaaccctgtgtatgtgggtaacgtggcatgggctcatattttgtca
gccaaggctatgaaagatttacacaaagtaaaacaaattggtggtcattttttttttatt
tctgatgacacaccacatatgagctactctgatttcaatgatgtgctgctaaagccactt
gggatcattgttccagagaaacttgaactaccaatgcccctgcttttttttcttgcattt
ttaatggaaatgttgcagtttttattgaaaccctttgtcaagtacactccatctatgaac
cggcagcttttaatcatgctcaacacacacttcaccttcacttatgcaaaggcacaaaag
gcttttggatacacaccaaggtacagatggactgaagccaaaacgacaacctctgagtgg
ctgtcatctgtgctgtcagagaggtgtgaacttgttaagaaaatgaaaactcactga
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