Phocoena sinus (vaquita): 116740798
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Entry
116740798 CDS
T07759
Symbol
ITCH
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog isoform X1
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
psiu
Phocoena sinus (vaquita)
Pathway
psiu04120
Ubiquitin mediated proteolysis
psiu04144
Endocytosis
psiu04330
Notch signaling pathway
psiu04668
TNF signaling pathway
psiu04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
psiu00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
116740798 (ITCH)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
116740798 (ITCH)
04668 TNF signaling pathway
116740798 (ITCH)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
116740798 (ITCH)
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
116740798 (ITCH)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
psiu04131
]
116740798 (ITCH)
04121 Ubiquitin system [BR:
psiu04121
]
116740798 (ITCH)
Enzymes [BR:
psiu01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
116740798 (ITCH)
Membrane trafficking [BR:
psiu04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
116740798 (ITCH)
Ubiquitin system [BR:
psiu04121
]
Ubiquitin ligases (E3)
HECT type E3
116740798 (ITCH)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
116740798
NCBI-ProteinID:
XP_032462625
Ensembl:
ENSPSNG00000013334
UniProt:
A0A8C9C1Z8
LinkDB
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Position
15:complement(24668507..24780420)
Genome browser
AA seq
891 aa
AA seq
DB search
MEECGASVETPEPRLLPLLSEPVCRPVGVMSDSGSQLGSMGSLTMKSQLQITVISAKLKE
NKKNWFGPSPYVEVTVDGQSKKTEKCNNTNSPKWKQPLTVIVTPVSKLHFRVWSHQTLKS
DVLLGTAALDIYETLKSNNMKLEEVVVTLQLVGDKEPTETIGDLSVCLDGLQLESEVIAN
GETTCSESASQNDDGSRPKDETRASTNGSDHPEDAGSGENRRVNGNNSPSLSNGGFKPSR
PPRPSRPPPPTPRRPASVNGSPSATSESDGSSTGSLPPTNTNSNTSEGATSGLIIPLTIS
GGSGPRPLNPVPQAPLPPGWEQRVDQHGRVYYVDHIEKRTTWDRPEPLPPGWERRVDNMG
RIYYVDHFTRTTTWQRPTLESVRNYEQWQLQRSQLQGAMQQFNQRFIYGNQDLFATSQNK
EFDPLGPLPPGWEKRTDNNGRVYFVNHNTRITQWEDPRNQGQLNEKPLPEGWEMRFTVDG
IPYFVDHNRRTTTYIDPRTGKSALDNGPQIAYVRDFKAKVQYFRFWCQQLAMPQHIKITV
TRKTLFEDSFQQIMSFSPQDLRRRLWVIFPGEEGLDYGGVAREWFFLLSHEVLNPMYCLF
EYAGKDNYCLQINPASYINPDHLKYFRFIGRFIAMALFHGKFIDTGFSLPFYKRILNKPV
GLKDLESIDPEFYNSLIWVKENNIEECGLEMYFSVDKEILGEIKSHDLKPNGGNILVTEE
NKEEYIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQYLQYFDAKELEVLLCGMQEIDLND
WQRHAIYRHYTRTSKQIMWFWQFVKEIDNEKRMRLLQFVTGTCRLPVGGFADLMGSNGPQ
KFCIEKVGKENWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETEGFGQE
NT seq
2676 nt
NT seq
+upstream
nt +downstream
nt
atggaggagtgcggcgcgtcagtcgagaccccagagccgcggctgcttcctcttctctca
gagccggtttgccgtcctgttggtgttatgtctgacagtggatcacagcttggttcaatg
ggtagcctgaccatgaaatcacaacttcagataactgtcatttctgcgaaacttaaagaa
aataaaaagaattggtttgggccaagtccttatgtggaagtcacagtagatggacagtca
aagaagacagaaaaatgcaacaatacgaacagtcccaaatggaagcaacctcttacagtt
atcgtcacccctgtgagtaaattacattttcgtgtgtggagtcaccagacattgaaatct
gatgttttgttgggaactgctgcattagatatctatgaaacattaaagtcaaacaatatg
aaacttgaggaagtagttgtgactttacagcttgtaggtgacaaagaaccaacagagaca
ataggagatttgtcagtttgtcttgatgggctgcagctagagtctgaagttattgctaat
ggtgaaactacatgttcagaaagtgcttcacagaatgatgatggctccagacccaaggat
gaaacaagagcgagcacaaatggatcagaccatcctgaggatgcagggtctggtgaaaat
aggagggtcaatgggaacaattctccatcactctcaaatggcggttttaaaccttctagg
cctccaagaccttcacgaccacctccacctaccccacgtagaccagcatctgtcaatggc
tcaccatctgccacttctgaaagtgatggctctagtacaggctctctcccaccaacgaat
acaaattcaaatacatctgaaggagcaacatctggattaataattcctcttactatatct
ggaggttcaggccctaggccattaaatcctgtacctcaagctcccctcccacccggttgg
gagcagagagtggaccagcatgggcgagtttactatgtagatcatattgaaaaaagaaca
acgtgggatagaccagaacctctacctcctggctgggaacggcgggttgacaacatggga
cgtatttattatgttgaccatttcacaagaacaacgacgtggcagaggccaacattggaa
tccgtccggaactatgaacagtggcagctccaacgtagtcagcttcaaggagctatgcag
cagtttaaccagaggttcatttatgggaatcaagacttgtttgctacatcacaaaataaa
gaatttgatcccctgggtcccctgccacctggatgggagaagagaacggacaacaatggt
agagtatattttgtcaaccacaatactcgtattacacagtgggaagaccccagaaatcaa
ggtcaattaaatgaaaagcccttacctgaaggctgggaaatgaggttcacagtagatgga
attccatattttgtggaccacaatagaagaacaaccacctatatagatccccgcactgga
aaatctgccttagacaatggaccccagatagcctatgtacgggacttcaaggcaaaggtt
cagtatttccggttctggtgtcagcaactggccatgccacagcacataaagattacagtg
acaagaaaaacattgtttgaggattcctttcagcagataatgagcttcagtccccaagat
ctgcgaagacgtttgtgggtgatttttccaggagaagaaggtttagattatggaggtgta
gcaagagaatggttctttcttttgtcacatgaggtgttgaacccaatgtattgcctgttt
gaatatgcagggaaggataattactgcttgcagataaaccccgcttcttacatcaatcca
gatcacctgaaatattttcgttttattggcaggtttattgctatggctctgttccatggg
aaattcatagacacaggtttttctttgccattctataagcgtatcttgaacaaaccagtt
ggtctcaaggatttagaatctattgatccagaattttacaattctctcatctgggttaaa
gaaaacaatattgaggaatgtggtttggaaatgtatttttccgtcgataaagaaatttta
ggtgaaatcaagagtcatgatttgaaacccaatggtggcaatattcttgtaacagaagaa
aataaagaggagtatatcagaatggtagctgaatggaggttgtctcgcggtgttgaagaa
cagacacaagctttctttgagggctttaatgaaattcttccccagcagtatttgcagtac
tttgatgcaaaggaattagaggttcttttatgtggaatgcaagagattgatttgaatgac
tggcaaagacatgccatctaccgtcattacactaggacaagcaaacaaatcatgtggttt
tggcagtttgttaaagaaatcgataatgagaagagaatgagacttttgcagtttgttact
ggaacctgccgattgccagttggcggatttgctgacctcatggggagcaatgggccacag
aaattctgcattgaaaaagttgggaaagaaaattggttgcctagaagtcatacctgtttt
aaccgcctggacctgccaccctacaagagctatgagcaactgaaggaaaagctgttattt
gctattgaagaaacagaaggatttggacaagagtga
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