Phocoena sinus (vaquita): 116748068
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Entry
116748068 CDS
T07759
Symbol
IRS4
Name
(RefSeq) insulin receptor substrate 4 isoform X1
KO
K17446
insulin receptor substrate 4
Organism
psiu
Phocoena sinus (vaquita)
Pathway
psiu04022
cGMP-PKG signaling pathway
psiu04068
FoxO signaling pathway
psiu04081
Hormone signaling
psiu04140
Autophagy - animal
psiu04152
AMPK signaling pathway
psiu04211
Longevity regulating pathway
psiu04213
Longevity regulating pathway - multiple species
psiu04910
Insulin signaling pathway
psiu04920
Adipocytokine signaling pathway
psiu04923
Regulation of lipolysis in adipocytes
psiu04930
Type II diabetes mellitus
psiu04935
Growth hormone synthesis, secretion and action
psiu05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
psiu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
116748068 (IRS4)
04022 cGMP-PKG signaling pathway
116748068 (IRS4)
04152 AMPK signaling pathway
116748068 (IRS4)
09133 Signaling molecules and interaction
04081 Hormone signaling
116748068 (IRS4)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
116748068 (IRS4)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
116748068 (IRS4)
04923 Regulation of lipolysis in adipocytes
116748068 (IRS4)
04920 Adipocytokine signaling pathway
116748068 (IRS4)
04935 Growth hormone synthesis, secretion and action
116748068 (IRS4)
09149 Aging
04211 Longevity regulating pathway
116748068 (IRS4)
04213 Longevity regulating pathway - multiple species
116748068 (IRS4)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
116748068 (IRS4)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
116748068 (IRS4)
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Motif
Pfam:
IRS
PH_11
PH_8
PH
Motif
Other DBs
NCBI-GeneID:
116748068
NCBI-ProteinID:
XP_032476791
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Position
X:complement(92908165..92912079)
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AA seq
1270 aa
AA seq
DB search
MASCSFARDQATRRLRAAAAATAAALAAVAPTPLLSSGTPTALIGTGSSCPGAMWLSTAT
GSRSDSESDEEDLPVGDEVCKRGYLRKQKHGHRRYFVLKLETADAPARLEYYENARKFRH
SVRAAAAAAAAAASGAAVPALIPPRRVITLYQCFSVSQRADARYRHLIALFTQDEYFAMV
AENESEQESWYLLLSRLILESKRRRCGTPGAQPDGEPAALAAAAAAEPPFYKDVWQVIVK
PRGLGHRKELSGVFRLCLTDEEVVFVRLNTEVASVVVQLLSIRRCGHSEQYFFLEVGRST
VIGPGELWMQVDDCVVAQNMHELFLEKMRALCADEYRARCRSYSISIGAHLLTLLSTRRH
LDMLPLEPGGWLRRSRFEQFCHLRAIGDGEDEMLLARRYITPSEPVPHSRRGRLHLPRAR
RSRRAISVPASFFRRVAPSPVRGPHPAEAPSEGACLSSEAPGPGSGNSGEEGNPQGKEDQ
EGNGGDYMPMNNWGSGNGQGSGGGQGSSGQGSSSQSSGGSQCSGRGHGSGGGQGSSGSQG
SSGQGSGGQGAGGNQCSGDGQGTSGGHGSGSGQGAGGGHGSGRGQGPGDGHGSGRGRNSG
GSKGPGSGKGSEGNGDHGKSLKKRSYFGKLTQSKQQQMPPPSPPPPPPAAATGGKGKSGG
RFRLYFCADRRATKERKEAKEVKDTETPEGAAWGPHRARAFDEDEDDPYVPMRPGVAAPL
PSSSDYMPMAPQNVSVSKKRHSRSPFEDSRGYMMMFPRVSPPPAPSPAKAPDPDKEDDSK
DNDSDSDYMFMAPGAGAIPKNPRNPQGGSSSKSWSSYFSLPNAFRSSPLGQSDHSEYVPM
LPGKFLGKGLDKEASSNRGPKDVTSKPSVEGSFSKPRDEGSPSKRSGDGPPKNKTKRPNR
LPFITKGNKIKPKPQKPIHEQKEADSTSGYIKIDFPKRGSNMPAPCIQRLPGLWGIIADP
RQFAFSNYVNVEFGVPFPNPANDLSDLLRAIPGANPFSLDGARWPLPPLPPSATGNSANE
EEGDYIEVIFNPAMTPAVPFADSAIRYDAETGRIYVVDPFSECCMDISLSPSRCSEPPPV
ARLLLEEELERRRPQSRSQSFFAAARAAVSAFPTDSLERDLSASLAAATAAAAAPTLAVS
RALAAASTLVAAPGSGAAAAGLEAAAGSDSASVRRFQPAANAAGAEAVRGAQDVAGGSNP
RAQNPSADLAGGDRAGGAAAAAAAPPPSPGRGRAPRPPEQEDSDDDDDTYVRMDFARPDN
EKFDSPQRGW
NT seq
3813 nt
NT seq
+upstream
nt +downstream
nt
atggcgagttgctccttcgctcgcgaccaagcgacaaggagactgcgagctgcagcagcg
gcaacagcggcagctctagctgcggtggcgcccaccccacttctttcctcgggaaccccg
accgcactcattgggaccgggtcgtcttgtccgggagccatgtggctctccacggccacc
ggctcccggtcagactccgagtccgatgaggaggacctccccgtcggggacgaagtctgc
aaacgcggctacctgcggaagcagaagcatggccacaggcgctacttcgtgctcaaactg
gagaccgccgacgccccagctcgactggaatactacgaaaatgccaggaagttccggcac
agtgtccgcgccgcggcggctgcagcagcggcggctgcctctggcgccgcggtccccgcg
ctcatcccaccgcggcgcgtgatcaccctgtaccagtgcttctcggtgagccagcgagcc
gacgcaaggtaccgacacctcatcgctcttttcacccaggacgagtacttcgcgatggtg
gccgagaacgagtcggagcaagagagctggtacttgctgctcagccgcctcatcctcgag
agcaagcgccgccgctgcggcacgcccggcgcgcagccggatggagagccggccgcactg
gcggctgcagcggcggcggagccacccttctacaaagatgtgtggcaggtaatagtcaaa
cccagggggctggggcacagaaaagagctgagcggcgtgttccggctctgtcttaccgac
gaggaggttgtgtttgtgaggctaaataccgaagtggccagcgtggtcgtccagctcctg
agcatccgtcgctgcgggcactcggagcagtatttcttcttggaagtcggcaggtccacc
gtcatcggtccgggggagctctggatgcaggtcgatgactgtgtggtggcccaaaacatg
cacgagctgtttttggagaagatgagagccttgtgtgcagacgaatacagagcccgctgc
cgcagctacagcatcagtatcggcgcccacctgttaaccctgctgtccactaggaggcac
ctggacatgctgccgctcgagcctggcggctggctcagaaggtcccgctttgagcagttt
tgccacctcagggccatcggtgatggggaagacgagatgctccttgccaggcgctacata
acacccagtgagcctgtgccccactccaggcgaggaagactgcacctgcccagagcgcgg
agatccaggagagcgatttcagtgccagccagcttttttcgccgtgtagcacccagcccc
gtgcgtggcccgcaccctgcagaagcccccagcgagggagcttgcctgtcttctgaagca
cctggtcccggctctggcaactctggggaagaaggcaatcctcagggaaaagaggatcag
gaaggaaacggaggcgactatatgcccatgaacaattggggctccggaaatggccagggc
tcaggaggtggacagggttcaagtggccaaggttccagtagccagagctctggaggaagc
cagtgctcgggcagggggcacggctccggaggtggccagggctcaagtggcagccagggc
tcaagtggccagggctccgggggccagggtgcaggaggaaaccagtgctcaggagatggc
cagggcacctcaggtgggcatggctcaggcagtggccagggagctggaggtgggcacggc
tcaggccgtggccaaggacccggagatggccatggctcaggcaggggcaggaactctgga
gggagcaaaggcccaggaagtgggaaaggctccgaaggcaatggtgatcatgggaaatct
ctgaagaaaagatcctactttggcaaattaactcaaagcaagcaacagcaaatgccacca
ccttcaccacctccacccccaccagctgcagcaactggtggaaaaggaaagtctggggga
aggttccgactttatttttgtgctgacagaagagccacaaaagaacgcaaagaagccaaa
gaagttaaagacacagagaccccagaaggtgcagcttggggtccccacagggccagagct
tttgatgaagatgaggatgacccatatgtgccaatgaggccaggggtggctgcccctctc
ccaagctccagcgattatatgccaatggctcctcaaaatgtctctgtgtcaaagaagcgc
cactctcgatcacctttcgaagattcaagagggtacatgatgatgtttcccagagtgagc
ccaccacctgcaccaagtcctgcaaaagcacctgatcctgacaaagaggatgactcaaag
gacaatgacagtgacagtgactacatgtttatggctcctggagctggtgcaattccaaaa
aaccccagaaatcctcagggaggctcttcctccaaaagttggagctcctacttctctctg
ccaaatgcttttcggagctccccattggggcagagtgaccacagtgagtatgtaccaatg
ttacctggaaaattcctggggaagggcctagacaaagaagcctcatctaacagaggcccc
aaagatgtaacttcaaagccttcagttgaggggtcattctcaaagcctagagatgaggga
tcaccttccaagcgttcaggtgatgggccccccaagaacaagactaagagacctaatcga
cttccttttattacaaaagggaataaaatcaagccaaaaccacaaaagcccatacatgag
cagaaagaagccgacagcactagtggctacatcaagattgacttccctaaaagaggtagc
aatatgccagctccctgtattcaaagactgccaggtttgtggggcataattgccgacccc
agacagttcgccttttcgaattatgtgaatgttgagttcggagtgccatttccaaatcca
gcaaacgacctctcagatcttttaagagctattccaggtgccaaccccttctctctggac
ggtgctaggtggccacttccgcctcttcctcccagtgctacaggtaacagtgctaatgag
gaagaaggtgactacattgaagtgattttcaacccagcaatgacaccagccgtgcctttt
gctgacagtgccattcgctacgacgctgaaacaggtcgcatctacgtggtcgacccattt
tctgagtgctgtatggacatttctctctcccccagccgctgctctgaaccaccacctgta
gcgaggctgctgctggaagaagagctcgagagaagacgcccacaaagccgttcgcaaagt
ttctttgcagctgccagagccgccgtctctgctttcccgaccgacagcctcgagagagac
ctctccgcctctttagccgcggccacggccgcggcagccgcgccaaccttagccgtgagc
cgggctttagccgccgcctccaccctggtcgctgccccgggcagcggcgctgccgccgcg
ggcctcgaggccgccgcgggatctgactccgcctccgtccgccggttccaacctgctgct
aatgctgctggtgccgaagcggtaagaggggcccaagacgttgcgggtggctcgaacccc
agagcccaaaacccatcggcagaccttgcgggaggtgacagggccggcggggctgccgct
gcagccgccgctccccctccatcacctggccgcggccgggcgccgagacccccagagcaa
gaagattctgacgacgacgacgacacgtacgtgagaatggactttgccagacctgacaac
gagaagttcgactctccccaaagaggttggtga
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