Phocoena sinus (vaquita): 116757029 Help Entry 116757029         CDS       T07759                                  Symbol CASP8 Name (RefSeq) caspase-8 isoform X1   KO K04398   caspase 8 [EC:3.4.22.61] Organism psiu  Phocoena sinus (vaquita) Pathway psiu01524   Platinum drug resistance psiu04115   p53 signaling pathway psiu04210   Apoptosis psiu04215   Apoptosis - multiple species psiu04217   Necroptosis psiu04620   Toll-like receptor signaling pathway psiu04621   NOD-like receptor signaling pathway psiu04622   RIG-I-like receptor signaling pathway psiu04623   Cytosolic DNA-sensing pathway psiu04625   C-type lectin receptor signaling pathway psiu04657   IL-17 signaling pathway psiu04668   TNF signaling pathway psiu04932   Non-alcoholic fatty liver disease psiu04936   Alcoholic liver disease psiu05010   Alzheimer disease psiu05016   Huntington disease psiu05022   Pathways of neurodegeneration - multiple diseases psiu05132   Salmonella infection psiu05134   Legionellosis psiu05142   Chagas disease psiu05145   Toxoplasmosis psiu05152   Tuberculosis psiu05160   Hepatitis C psiu05161   Hepatitis B psiu05162   Measles psiu05163   Human cytomegalovirus infection psiu05164   Influenza A psiu05165   Human papillomavirus infection psiu05167   Kaposi sarcoma-associated herpesvirus infection psiu05168   Herpes simplex virus 1 infection psiu05169   Epstein-Barr virus infection psiu05170   Human immunodeficiency virus 1 infection psiu05200   Pathways in cancer psiu05203   Viral carcinogenesis psiu05416   Viral myocarditis psiu05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:psiu00001]  09130 Environmental Information Processing   09132 Signal transduction    04668 TNF signaling pathway     116757029 (CASP8)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     116757029 (CASP8)    04215 Apoptosis - multiple species     116757029 (CASP8)    04217 Necroptosis     116757029 (CASP8)    04115 p53 signaling pathway     116757029 (CASP8)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     116757029 (CASP8)    04621 NOD-like receptor signaling pathway     116757029 (CASP8)    04622 RIG-I-like receptor signaling pathway     116757029 (CASP8)    04623 Cytosolic DNA-sensing pathway     116757029 (CASP8)    04625 C-type lectin receptor signaling pathway     116757029 (CASP8)    04657 IL-17 signaling pathway     116757029 (CASP8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     116757029 (CASP8)    05203 Viral carcinogenesis     116757029 (CASP8)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     116757029 (CASP8)    05161 Hepatitis B     116757029 (CASP8)    05160 Hepatitis C     116757029 (CASP8)    05164 Influenza A     116757029 (CASP8)    05162 Measles     116757029 (CASP8)    05168 Herpes simplex virus 1 infection     116757029 (CASP8)    05163 Human cytomegalovirus infection     116757029 (CASP8)    05167 Kaposi sarcoma-associated herpesvirus infection     116757029 (CASP8)    05169 Epstein-Barr virus infection     116757029 (CASP8)    05165 Human papillomavirus infection     116757029 (CASP8)   09171 Infectious disease: bacterial    05132 Salmonella infection     116757029 (CASP8)    05134 Legionellosis     116757029 (CASP8)    05152 Tuberculosis     116757029 (CASP8)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     116757029 (CASP8)    05142 Chagas disease     116757029 (CASP8)   09164 Neurodegenerative disease    05010 Alzheimer disease     116757029 (CASP8)    05016 Huntington disease     116757029 (CASP8)    05022 Pathways of neurodegeneration - multiple diseases     116757029 (CASP8)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     116757029 (CASP8)    05416 Viral myocarditis     116757029 (CASP8)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     116757029 (CASP8)    04932 Non-alcoholic fatty liver disease     116757029 (CASP8)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     116757029 (CASP8)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:psiu01002]     116757029 (CASP8) Enzymes [BR:psiu01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.61  caspase-8      116757029 (CASP8) Peptidases and inhibitors [BR:psiu01002]  Cysteine peptidases   Family C14: caspase family    116757029 (CASP8) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Peptidase_C14 DED ERM_C Motif Other DBs NCBI-GeneID:  116757029 NCBI-ProteinID:  XP_032494184 Ensembl:  ENSPSNG00000017590 LinkDB All DBs Position 7:complement(34577339..34618105) Genome browser AA seq 497 aa AA seqDB search MNFNRCLYNIGEQLDSEDLAALKFLSLDYIPHRKQEPIKDALVLFQRLQEKRMLEESNLS FLKELLFRMKRLDLLLTYLDTSEEEMERELQMPGRAQISAYRVMLFQISEDVNKLELKDF KFFLSQEIAKCKLDDDMTLLDIFIEMEKRVILGERNLDTLKKICEQINKSLLKKINDYEE LSREQRMSLGRGPDEFSNDVSQLLIRGGSLEMLAMSDSPGEKDSESQGQLLGWIFVFQTS NTVYRMKSKPRGYCLIFNNYDFSIARKDVPKLHSIKDRNGTDLDAEALRKTFNELHFEIV HYKDYTAKKICEVLKSYQSMDHNNKDCFICCILSHGDKGIIYGSDGQEAPIYELTSYFTG SKCPSLLGKPKIFFIQACQGDNYQRGIAVETDSEQKETYLEMDSSLQKRYIPDEADFLLG MATVNNCVSYRSTMEGTWYIQTLCQSLRERCPRGEDILSILTKVNFEVSNKDDKKNMGKQ MPQPTFTLRKKLFFPLN NT seq 1494 nt NT seq  +upstreamnt  +downstreamnt atgaatttcaacagatgtctgtataatattggagaacagctggacagtgaagacctggct gccctcaagttcctgagcctggactacattccacataggaagcaggaacccatcaaggat gccttggtgctattccagaggctccaagaaaagagaatgttggaggaaagcaacctgtcc ttcttgaaggagctgcttttccgaatgaaaagactggatctgctgctcacctacctggac accagtgaggaggagatggagagggagcttcagatgccgggcagggcccagatctctgcc tatagggtcatgctttttcagatttcagaagatgtgaacaaactggaattgaaggacttc aagttttttttgagccaggagatcgccaaatgtaagctggatgatgacatgaccttgctt gatattttcatagagatggagaagagggtcatcctaggggaaagaaacttggacaccctg aaaaaaatctgtgagcaaatcaacaagagcttgctgaagaaaatcaacgattatgaagaa ctaagcagagagcaaagaatgagccttggaagaggtccagatgaattttcaaacgatgtg tcccaattgctcataagggggggctcccttgaaatgctggccatgtcggactctccagga gaaaaggacagtgagtcacagggtcagctcctgggttggatttttgttttccagacatcg aacacagtttaccgaatgaaaagcaaacctcggggatactgtttgatctttaacaattat gattttagcatagcaaggaaggatgtgcccaagcttcacagcattaaggataggaatgga acagacttggatgcagaggctttgagaaagacctttaatgagcttcattttgagatagtg cattacaaagactacactgcgaagaaaatctgtgaggttctgaaatcctaccaaagcatg gaccacaataacaaggactgcttcatctgctgcatcctctcccatggagacaaaggcatc atctatggctccgatgggcaggaagcccccatctatgagctgacctcttacttcactggt tcaaagtgcccttcccttcttggcaaacccaaaatcttttttattcaggcttgtcaaggg gataactaccagagaggtatagctgttgaaactgactcagaacagaaggaaacctattta gaaatggattcatcgcttcagaagagatatatcccagatgaggctgactttctgctggga atggccaccgtgaacaactgtgtttcctaccgaagcaccatggaggggacctggtatatc cagacactttgccagagcctgagagaaagatgtcctaggggtgaagatattctcagcatc ctcaccaaggtgaactttgaagtaagcaataaggatgacaagaaaaatatgggcaaacag atgccacaacctactttcacactgaggaaaaaactcttctttccccttaattga

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