Phocoena sinus (vaquita): 116759447 Help Entry 116759447         CDS       T07759                                  Symbol LCK Name (RefSeq) tyrosine-protein kinase Lck   KO K05856   lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2] Organism psiu  Phocoena sinus (vaquita) Pathway psiu04064   NF-kappa B signaling pathway psiu04380   Osteoclast differentiation psiu04650   Natural killer cell mediated cytotoxicity psiu04658   Th1 and Th2 cell differentiation psiu04659   Th17 cell differentiation psiu04660   T cell receptor signaling pathway psiu05135   Yersinia infection psiu05166   Human T-cell leukemia virus 1 infection psiu05235   PD-L1 expression and PD-1 checkpoint pathway in cancer psiu05340   Primary immunodeficiency Brite KEGG Orthology (KO) [BR:psiu00001]  09130 Environmental Information Processing   09132 Signal transduction    04064 NF-kappa B signaling pathway     116759447 (LCK)  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     116759447 (LCK)    04660 T cell receptor signaling pathway     116759447 (LCK)    04658 Th1 and Th2 cell differentiation     116759447 (LCK)    04659 Th17 cell differentiation     116759447 (LCK)   09158 Development and regeneration    04380 Osteoclast differentiation     116759447 (LCK)  09160 Human Diseases   09161 Cancer: overview    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     116759447 (LCK)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     116759447 (LCK)   09171 Infectious disease: bacterial    05135 Yersinia infection     116759447 (LCK)   09163 Immune disease    05340 Primary immunodeficiency     116759447 (LCK)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:psiu01001]     116759447 (LCK)   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:psiu03036]     116759447 (LCK) Enzymes [BR:psiu01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      116759447 (LCK) Protein kinases [BR:psiu01001]  Non-receptor tyrosine kinases   SRC family    116759447 (LCK) Chromosome and associated proteins [BR:psiu03036]  Eukaryotic type   Centrosome formation proteins    Kinases and associated factors     116759447 (LCK) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase SH2 SH3_1 SH3_2 SH3_9 ABC1 SH2_1 SH3_16 Haspin_kinase Kdo SH3_3 DUF7063 Motif Other DBs NCBI-GeneID:  116759447 NCBI-ProteinID:  XP_032499128 Ensembl:  ENSPSNG00000012181 LinkDB All DBs Position 1:25735910..25755623 Genome browser AA seq 509 aa AA seqDB search MGCSCSSNPEDDWMENIDVCENCHYPIVPLEGKAMLSTWNGSEVRDPLVTYEGSNPPASP LQDNLVIALHSYEPSHDGDLGFEKGEQLRILEQNGEWWKAQSVTTGQEGYIPFNFVARAN SLEPEPWFFKTLTRKDAERQLLAPGNTHGSFLIRESESTTGSFSLSVRDFDQTQGEVVKH YKIRNLDKGGFYISPRITFPGLHELVRHYMNSSDGLCTRLSRPCQTQKPQKPWWEDEWEV PRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRL VRLYAVVTQEPIYIITEYMENGSLVDFLKTSTGIKLTINKLLDMAAQIAEGMAFIEERNY IHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIK SDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLEQGYRMVRPDNCPDELYQLMMLCWKEL PEDRPTFDYLRSVLEDFFTATEGQYQPQP NT seq 1530 nt NT seq  +upstreamnt  +downstreamnt atgggctgtagctgcagctcaaaccctgaagatgactggatggaaaacatcgatgtgtgt gagaactgccattaccccatagttccactggagggcaaggccatgctgtccacctggaat ggctctgaagtgcgggatccactggtcacctacgagggctccaaccccccagcttctcca ctgcaagacaacctggttatcgccctgcacagctatgagccttcccacgatggagatctg ggcttcgagaagggtgaacagctacgtatcctggagcagaacggcgagtggtggaaggcg cagtccgtgaccacgggccaggaaggttacatccccttcaactttgtggccagagcgaac agcctggagcccgaaccctggttcttcaagaccctgacccgcaaggacgcggagaggcag ctcctggcgcccgggaacacgcacggctccttcctgatccgagagagtgaaagcaccacg ggatcgttttcactgtccgtccgggacttcgaccagacccagggagaagtggtgaaacat tacaagatccgtaacctggacaaaggcggcttctacatctccccccgcatcacttttcct ggcttgcatgagctggtccgccattacatgaactcttcggacgggctgtgcacgaggttg agccgcccctgccagacccagaagccccagaagccctggtgggaggatgagtgggaggtt cccagggagacgctgaagctggtggagcggctgggggctggccagttcggagaggtgtgg atggggtactacaacgggcacacgaaggtggcagtgaagagcctgaagcagggcagcatg tctcccgatgccttcctggccgaggccaacctcatgaagcagctgcaacaccagcggctg gtccggctctacgcggtggtcacccaggagcccatctacatcatcacggaatacatggag aatgggagcctggtggattttctcaagacctccacaggcatcaagctgaccatcaacaaa ctcttggacatggcagcccaaattgcagagggcatggcattcattgaagagcggaattat atccaccgtgacttgagggccgccaacatcctggtgtctgataccctgagctgcaagatc gcagactttggcctagcacgcctcattgaggacaatgagtacacagccagggagggggcc aagtttcccattaagtggacagcaccagaagccattaactatgggacattcaccatcaag tcagacgtgtggtctttcgggatcctgctgacggagattgtcactcatggccgcatccct tacccagggatgaccaatcctgaggtgattcagaacctggagcaaggctaccgcatggta cgacctgacaactgtccagatgagttgtaccaacttatgatgctgtgctggaaggagctc ccggaggaccggcccacctttgactacctgcgcagtgtgctggaggacttcttcacagcc acagagggccagtaccagccgcagccctga

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